1LGQ
 
 | | Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein | | 分子名称: | cell cycle checkpoint protein CHFR | | 著者 | Stavridi, E.S, Huyen, Y, Loreto, I.R, Scolnick, D.M, Halazonetis, T.D, Pavletich, N.P, Jeffrey, P.D. | | 登録日 | 2002-04-16 | | 公開日 | 2002-05-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein and its complex with tungstate.
Structure, 10, 2002
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1LGP
 | | Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein complexed with tungstate | | 分子名称: | TUNGSTATE(VI)ION, cell cycle checkpoint protein CHFR | | 著者 | Stavridi, E.S, Huyen, Y, Loreto, I.R, Scolnick, D.M, Halazonetis, T.D, Pavletich, N.P, Jeffrey, P.D. | | 登録日 | 2002-04-16 | | 公開日 | 2002-05-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein and its complex with tungstate.
Structure, 10, 2002
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1J4O
 | | REFINED NMR STRUCTURE OF THE FHA1 DOMAIN OF YEAST RAD53 | | 分子名称: | PROTEIN KINASE SPK1 | | 著者 | Yuan, C, Yongkiettrakul, S, Byeon, I.-J.L, Zhou, S, Tsai, M.-D. | | 登録日 | 2001-10-03 | | 公開日 | 2001-12-05 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of two FHA1-phosphothreonine peptide complexes provide insight into the structural basis of the ligand specificity of FHA1 from yeast Rad53.
J.Mol.Biol., 314, 2001
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1K2M
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5DJO
 | | Crystal structure of the CC1-FHA tandem of Kinesin-3 KIF13A | | 分子名称: | ACETIC ACID, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ... | | 著者 | Ren, J.Q, Li, W, Huo, L, Feng, W. | | 登録日 | 2015-09-02 | | 公開日 | 2015-12-30 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Structural Correlation of the Neck Coil with the Coiled-coil (CC1)-Forkhead-associated (FHA) Tandem for Active Kinesin-3 KIF13A
J.Biol.Chem., 291, 2016
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2AFF
 | | The solution structure of the Ki67FHA/hNIFK(226-269)3P complex | | 分子名称: | Antigen KI-67, MKI67 FHA domain interacting nucleolar phosphoprotein | | 著者 | Byeon, I.-J.L, Li, H, Song, H, Gronenborn, A.M, Tsai, M.D. | | 登録日 | 2005-07-25 | | 公開日 | 2005-10-25 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Sequential phosphorylation and multisite interactions characterize specific target recognition by the FHA domain of Ki67.
Nat.Struct.Mol.Biol., 12, 2005
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4EGX
 | | Crystal structure of KIF1A CC1-FHA tandem | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Kinesin-like protein KIF1A | | 著者 | Yu, J, Huo, L, Yue, Y, Xu, T, Zhang, M, Feng, W. | | 登録日 | 2012-04-02 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | The CC1-FHA Tandem as a Central Hub for Controlling the Dimerization and Activation of Kinesin-3 KIF1A
Structure, 20, 2012
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4EJQ
 | | Crystal structure of KIF1A C-CC1-FHA | | 分子名称: | Kinesin-like protein KIF1A | | 著者 | Huo, L, Yue, Y, Ren, J, Yu, J, Liu, J, Yu, Y, Ye, F, Xu, T, Zhang, M, Feng, W. | | 登録日 | 2012-04-06 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.893 Å) | | 主引用文献 | The CC1-FHA Tandem as a Central Hub for Controlling the Dimerization and Activation of Kinesin-3 KIF1A
Structure, 20, 2012
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5A8I
 | | Crystal structure of the FHA domain of ArnA from Sulfolobus acidocaldarius | | 分子名称: | ARNA, GLYCEROL, SULFATE ION | | 著者 | Hoffmann, L, Anders, K, Reimann, J, Linne, U, Essen, L.-O, Albers, S.-V. | | 登録日 | 2015-07-16 | | 公開日 | 2016-06-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Phosphorylation-Dependent Interaction between an Archaeal Von Willebrand and Fha Domain Recruits Arna-Arnb Complex to DNA for Repression of Motility
To be Published
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6HBZ
 | | Bdellovibrio bacteriovorus DgcB Full-length | | 分子名称: | 1,2-ETHANEDIOL, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CHLORIDE ION, ... | | 著者 | Lovering, A.L, Meek, R.W. | | 登録日 | 2018-08-13 | | 公開日 | 2019-08-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Structural basis for activation of a diguanylate cyclase required for bacterial predation in Bdellovibrio.
Nat Commun, 10, 2019
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6I2R
 | | Crystal structure of the SucA domain of Mycobacterium smegmatis KGD (alpha-ketoglutarate decarboxylase), mutant R802A, in complex with GarA | | 分子名称: | CALCIUM ION, Glycogen accumulation regulator GarA, MAGNESIUM ION, ... | | 著者 | Wagner, T, Bellinzoni, M, Alzari, P.M. | | 登録日 | 2018-11-01 | | 公開日 | 2019-05-22 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling.
Sci.Signal., 12, 2019
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6I2S
 | | Crystal structure of the SucA domain of Mycobacterium smegmatis KGD (R802A) in complex with GarA, following 2-oxoglutarate soak | | 分子名称: | (4S)-4-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3lambda~5~-thiazol-2-yl}-4-hydroxybutanoic acid, CALCIUM ION, Glycogen accumulation regulator GarA, ... | | 著者 | Wagner, T, Bellinzoni, M, Alzari, P.M. | | 登録日 | 2018-11-01 | | 公開日 | 2019-05-22 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling.
Sci.Signal., 12, 2019
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6I2Q
 | | Crystal structure of the wild-type SucA domain of Mycobacterium smegmatis KGD (alpha-ketoglutarate decarboxylase), in complex with GarA | | 分子名称: | CALCIUM ION, Glycogen accumulation regulator GarA, MAGNESIUM ION, ... | | 著者 | Wagner, T, Bellinzoni, M, Alzari, P.M. | | 登録日 | 2018-11-01 | | 公開日 | 2019-05-22 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling.
Sci.Signal., 12, 2019
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7WRG
 | | Crystal structure of full-length kinesin-3 KLP-6 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein, MAGNESIUM ION | | 著者 | Wang, W.J, Ren, J.Q, Song, W.Y, Feng, W. | | 登録日 | 2022-01-26 | | 公開日 | 2022-08-10 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.16 Å) | | 主引用文献 | The architecture of kinesin-3 KLP-6 reveals a multilevel-lockdown mechanism for autoinhibition.
Nat Commun, 13, 2022
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6FF7
 | | human Bact spliceosome core structure | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ... | | 著者 | Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. | | 登録日 | 2018-01-03 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
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5GM6
 | | Cryo-EM structure of the activated spliceosome (Bact complex) at 3.5 angstrom resolution | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cold sensitive U2 snRNA suppressor 1, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Yan, C, Wan, R, Bai, R, Huang, G, Shi, Y. | | 登録日 | 2016-07-12 | | 公開日 | 2016-09-21 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure of a yeast activated spliceosome at 3.5 angstrom resolution
Science, 353, 2016
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5LQW
 | | yeast activated spliceosome | | 分子名称: | Pre-mRNA leakage protein 1, Pre-mRNA-processing protein 45, Pre-mRNA-splicing factor 8, ... | | 著者 | Rauhut, R, Luehrmann, R. | | 登録日 | 2016-08-17 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | | 主引用文献 | Molecular architecture of the Saccharomyces cerevisiae activated spliceosome
Science, 6306, 2016
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7ZR1
 | | Chaetomium thermophilum Mre11-Rad50-Nbs1 complex bound to ATPyS (composite structure) | | 分子名称: | DH domain-containing protein, Double-strand break repair protein, FHA domain-containing protein, ... | | 著者 | Bartho, J.D, Rotheneder, M, Stakyte, K, Lammens, K, Hopfner, K.P. | | 登録日 | 2022-05-03 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions.
Mol.Cell, 83, 2023
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7DVQ
 | | Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex) | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'-O-[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(methoxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]guanosine, Armadillo repeat-containing protein 7, ... | | 著者 | Bai, R, Wan, R, Wang, L, Xu, K, Zhang, Q, Lei, J, Shi, Y. | | 登録日 | 2021-01-14 | | 公開日 | 2021-03-31 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Structure of the activated human minor spliceosome.
Science, 371, 2021
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8BAH
 | | Human Mre11-Nbs1 complex | | 分子名称: | Double-strand break repair protein MRE11, MANGANESE (II) ION, Nibrin | | 著者 | Bartho, J.D, Rotheneder, M, Stakyte, K, Lammens, K, Hopfner, K.P. | | 登録日 | 2022-10-11 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (4.13 Å) | | 主引用文献 | Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions.
Mol.Cell, 83, 2023
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8P5R
 | | Crystal structure of full-length, homohexameric 2-oxoglutarate dehydrogenase KGD from Mycobacterium smegmatis in complex with GarA | | 分子名称: | CALCIUM ION, Glycogen accumulation regulator GarA, MAGNESIUM ION, ... | | 著者 | Wagner, T, Mechaly, A.M, Alzari, P.M, Bellinzoni, M. | | 登録日 | 2023-05-24 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (4.562 Å) | | 主引用文献 | High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase.
Nat Commun, 14, 2023
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8P5X
 | | Single particle cryo-EM structure of the complex between Corynebacterium glutamicum homohexameric 2-oxoglutarate dehydrogenase OdhA and the FHA-protein inhibitor OdhI | | 分子名称: | 2-oxoglutarate dehydrogenase E1/E2 component, MAGNESIUM ION, Oxoglutarate dehydrogenase inhibitor, ... | | 著者 | Yang, L, Mechaly, A.M, Bellinzoni, M. | | 登録日 | 2023-05-24 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (2.29 Å) | | 主引用文献 | High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase.
Nat Commun, 14, 2023
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7DCO
 | | Cryo-EM structure of the activated spliceosome (Bact complex) at an atomic resolution of 2.5 angstrom | | 分子名称: | BJ4_G0014900.mRNA.1.CDS.1, BJ4_G0027490.mRNA.1.CDS.1, BJ4_G0037700.mRNA.1.CDS.1, ... | | 著者 | Bai, R, Wan, R, Yan, C, Qi, J, Zhang, P, Lei, J, Shi, Y. | | 登録日 | 2020-10-26 | | 公開日 | 2021-03-17 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2.
Science, 371, 2021
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3MDB
 | | Crystal structure of the ternary complex of full length centaurin alpha-1, KIF13B FHA domain, and IP4 | | 分子名称: | (2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dioctanoate, Arf-GAP with dual PH domain-containing protein 1, Kinesin-like protein KIF13B, ... | | 著者 | Shen, L, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2010-03-30 | | 公開日 | 2010-08-04 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.952 Å) | | 主引用文献 | Crystal structure of the ternary complex of full length centaurin alpha-1, KIF13B FHA domain, and IP4
to be published
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7ABG
 | | Human pre-Bact-1 spliceosome | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cell division cycle 5-like protein, ... | | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | | 登録日 | 2020-09-07 | | 公開日 | 2020-12-23 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
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