PDB: 120 件ウェブページステータス検索Chemie searchBIRD

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5M8N	Crystal structure of human tyrosinase related protein 1 in complex with mimosine 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Lai, X, Soler-Lopez, M, Wichers, H.J, Dijkstra, B.W. 登録日 2016-10-29 公開日 2017-07-12 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis. Angew. Chem. Int. Ed. Engl., 56, 2017
5M8R	Crystal structure of human tyrosinase related protein 1 (T391V-R374S-Y362F) in complex with mimosine 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Lai, X, Soler-Lopez, M, Wichers, H.J, Dijkstra, B.W. 登録日 2016-10-29 公開日 2017-07-12 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis. Angew. Chem. Int. Ed. Engl., 56, 2017
5OAE	Crystal Structure of tyrosinase from Bacillus megaterium with SVF inhibitor in the active site 分子名称: 1-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]ethanone, COPPER (II) ION, Tyrosinase 著者 Deri, B, Gitto, R, Pazy Benhar, Y, Fishman, A. 登録日 2017-06-21 公開日 2018-04-25 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Targeting Tyrosinase: Development and Structural Insights of Novel Inhibitors Bearing Arylpiperidine and Arylpiperazine Fragments. J. Med. Chem., 61, 2018
5OR4	Crystal structure of Aspergillus oryzae catechol oxidase in deoxy-form 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ... 著者 Hakulinen, N, Penttinen, L, Rutanen, C, Rouvinen, J. 登録日 2017-08-15 公開日 2018-05-09 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.445 Å) 主引用文献 A new crystal form of Aspergillus oryzae catechol oxidase and evaluation of copper site structures in coupled binuclear copper enzymes. PLoS ONE, 13, 2018
5OR3	Crystal structure of Aspergillus oryzae catechol oxidase in met/deoxy-form 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Hakulinen, N, Penttinen, L, Rutanen, C, Rouvinen, J. 登録日 2017-08-15 公開日 2018-05-09 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.795 Å) 主引用文献 A new crystal form of Aspergillus oryzae catechol oxidase and evaluation of copper site structures in coupled binuclear copper enzymes. PLoS ONE, 13, 2018
6EI4	Crystal Structure of tyrosinase from Bacillus megaterium with B5N inhibitor in the active site 分子名称: COPPER (II) ION, Tyrosinase, [4-[(4-fluorophenyl)methyl]piperazin-1-yl]-(2-methylphenyl)methanone 著者 Deri, B, Gitto, R, Pazy Benhar, Y, Fishman, A. 登録日 2017-09-17 公開日 2018-04-25 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Targeting Tyrosinase: Development and Structural Insights of Novel Inhibitors Bearing Arylpiperidine and Arylpiperazine Fragments. J. Med. Chem., 61, 2018
6ELS	Structure of latent apple tyrosinase (MdPPO1) 分子名称: COPPER (II) ION, OXYGEN ATOM, Polyphenol oxidase, ... 著者 Kampatsikas, I, Bijelic, A, Pretzler, M, Rompel, A. 登録日 2017-09-29 公開日 2019-03-20 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.346 Å) 主引用文献 A Peptide-Induced Self-Cleavage Reaction Initiates the Activation of Tyrosinase. Angew.Chem.Int.Ed.Engl., 58, 2019
5Z0E	Crystal structure of copper-bound tyrosinase from Streptomyces castaneoglobisporus in complex with the Y98F mutant of the caddie protein obtained by soaking in the hydroxylamine-containing solution for 2 h at 298 K 分子名称: COPPER (II) ION, MelC, NITRATE ION, ... 著者 Matoba, Y, Sugiyama, M. 登録日 2017-12-19 公開日 2018-12-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.16 Å) 主引用文献 Catalytic mechanism of tyrosinase implied from the quinone formation on the Tyr98 residue of the caddie protein To Be Published
5Z0L	Crystal structure of copper-bound tyrosinase from Streptomyces castaneoglobisporus in complex with the caddie protein obtained by soaking in the hydroxylamine-containing solution for 9 h at 277 K 分子名称: COPPER (II) ION, MelC, NITRATE ION, ... 著者 Matoba, Y, Sugiyama, M. 登録日 2017-12-19 公開日 2018-12-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.17 Å) 主引用文献 Catalytic mechanism of tyrosinase implied from the quinone formation on the Tyr98 residue of the caddie protein To Be Published
5Z0F	Crystal structure of copper-bound tyrosinase from Streptomyces castaneoglobisporus in complex with the caddie protein obtained by soaking in the hydroxylamine-containing solution for 10 min at 298 K 分子名称: COPPER (II) ION, MelC, NITRATE ION, ... 著者 Matoba, Y, Sugiyama, M. 登録日 2017-12-19 公開日 2018-12-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.16 Å) 主引用文献 Catalytic mechanism of tyrosinase implied from the quinone formation on the Tyr98 residue of the caddie protein To Be Published
5Z0M	Crystal structure of copper-bound H63F-mutated tyrosinase from Streptomyces castaneoglobisporus in complex with the caddie protein obtained by soaking in the hydroxylamine-containing solution for 12 h at 298 K 分子名称: COPPER (II) ION, MelC, NITRATE ION, ... 著者 Matoba, Y, Sugiyama, M. 登録日 2017-12-19 公開日 2018-12-26 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Catalytic mechanism of tyrosinase implied from the quinone formation on the Tyr98 residue of the caddie protein To Be Published
5Z0K	Crystal structure of copper-bound tyrosinase from Streptomyces castaneoglobisporus in complex with the caddie protein obtained by soaking in the hydroxylamine-containing solution for 4 h at 277 K 分子名称: COPPER (II) ION, MelC, NITRATE ION, ... 著者 Matoba, Y, Sugiyama, M. 登録日 2017-12-19 公開日 2018-12-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Catalytic mechanism of tyrosinase implied from the quinone formation on the Tyr98 residue of the caddie protein To Be Published
5Z0D	1.16 A-resolution crystal structure of the deoxy-form tyrosinase from Streptomyces castaneoglobisporus in complex with the caddie protein 分子名称: COPPER (II) ION, MelC, NITRATE ION, ... 著者 Matoba, Y, Sugiyama, M. 登録日 2017-12-19 公開日 2018-12-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.16 Å) 主引用文献 Catalytic mechanism of tyrosinase implied from the quinone formation on the Tyr98 residue of the caddie protein To Be Published
5Z0J	Crystal structure of copper-bound tyrosinase from Streptomyces castaneoglobisporus in complex with the caddie protein obtained by soaking in the hydroxylamine-containing solution for 2 h at 277 K 分子名称: COPPER (II) ION, MelC, NITRATE ION, ... 著者 Matoba, Y, Sugiyama, M. 登録日 2017-12-19 公開日 2018-12-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Catalytic mechanism of tyrosinase implied from the quinone formation on the Tyr98 residue of the caddie protein To Be Published
5Z0I	Crystal structure of copper-bound tyrosinase from Streptomyces castaneoglobisporus in complex with the caddie protein obtained by soaking in the hydroxylamine-containing solution for 1 h at 277 K 分子名称: COPPER (II) ION, MelC, NITRATE ION, ... 著者 Matoba, Y, Sugiyama, M. 登録日 2017-12-19 公開日 2018-12-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 Catalytic mechanism of tyrosinase implied from the quinone formation on the Tyr98 residue of the caddie protein To Be Published
5Z0H	Crystal structure of copper-bound tyrosinase from Streptomyces castaneoglobisporus in complex with the caddie protein obtained by soaking in the hydroxylamine-containing solution for 2 h at 298 K 分子名称: COPPER (II) ION, MelC, NITRATE ION, ... 著者 Matoba, Y, Sugiyama, M. 登録日 2017-12-19 公開日 2018-12-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.18 Å) 主引用文献 Catalytic mechanism of tyrosinase implied from the quinone formation on the Tyr98 residue of the caddie protein To Be Published
5Z0G	Crystal structure of copper-bound tyrosinase from Streptomyces castaneoglobisporus in complex with the caddie protein obtained by soaking in the hydroxylamine-containing solution for 20 min at 298 K 分子名称: COPPER (II) ION, MelC, NITRATE ION, ... 著者 Matoba, Y, Sugiyama, M. 登録日 2017-12-19 公開日 2018-12-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 Catalytic mechanism of tyrosinase implied from the quinone formation on the Tyr98 residue of the caddie protein To Be Published
5ZRD	Tyrosinase from Burkholderia thailandensis (BtTYR) at low pH condition 分子名称: CITRIC ACID, COPPER (II) ION, GLYCEROL, ... 著者 Lee, S, Son, H.-F, Kim, K.-J. 登録日 2018-04-24 公開日 2018-10-31 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Basis for Highly Efficient Production of Catechol Derivatives at Acidic pH by Tyrosinase from Burkholderia thailandensis Acs Catalysis, 8, 2018
5ZRE	Tyrosinase from Burkholderia thailandensis (BtTYR) at high pH condition 分子名称: COPPER (II) ION, GLYCEROL, OXYGEN ATOM, ... 著者 Lee, S, Son, H.-F, Kim, K.-J. 登録日 2018-04-24 公開日 2018-10-31 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Basis for Highly Efficient Production of Catechol Derivatives at Acidic pH by Tyrosinase from Burkholderia thailandensis Acs Catalysis, 8, 2018
6GSG	Crystal structure of Aspergillus oryzae catechol oxidase complexed with resorcinol 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, Catechol oxidase, ... 著者 Penttinen, L, Hakulinen, N, Rouvinen, J. 登録日 2018-06-14 公開日 2018-09-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.192 Å) 主引用文献 Unraveling Substrate Specificity and Catalytic Promiscuity of Aspergillus oryzae Catechol Oxidase. Chembiochem, 19, 2018
6HQI	holo-form of polyphenol oxidase from Solanum lycopersicum 分子名称: COPPER (II) ION, OXYGEN ATOM, Polyphenol oxidase A, ... 著者 Kampatsikas, I, Bijelic, A, Rompel, A. 登録日 2018-09-25 公開日 2019-03-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Biochemical and structural characterization of tomato polyphenol oxidases provide novel insights into their substrate specificity. Sci Rep, 9, 2019
6HQJ	apo-form of polyphenol oxidase from Solanum lycopersicum 分子名称: Polyphenol oxidase A, chloroplastic 著者 Kampatsikas, I, Bijelic, A, Rompel, A. 登録日 2018-09-25 公開日 2019-03-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.802 Å) 主引用文献 Biochemical and structural characterization of tomato polyphenol oxidases provide novel insights into their substrate specificity. Sci Rep, 9, 2019
6J2U	Crystal structure of Tyrosinase caddy protein(MelC1)with Tyrosinase (MelC2)from Streptomyces avermitilis in complex with Zinc ion 分子名称: Tyrosinase, Tyrosinase co-factor protein, ZINC ION 著者 Lee, S.-H, Hong, H, Kim, K.-J. 登録日 2019-01-03 公開日 2020-02-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal structure of Tyrosinase caddy protein(MelC1)with tyrosinase (MelC2)from Streptomyces avermitilis in complex with Zinc ion To Be Published
6QXD	Crystal Structure of tyrosinase from Bacillus megaterium with JKB inhibitor in the active site. 分子名称: (2,4-dinitrophenyl)-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]methanone, COPPER (II) ION, Tyrosinase 著者 Deri Zenaty, B, Gitto, R, Pazy, Y, Fishman, A. 登録日 2019-03-07 公開日 2019-06-19 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.317 Å) 主引用文献 Exploiting the 1-(4-fluorobenzyl)piperazine fragment for the development of novel tyrosinase inhibitors as anti-melanogenic agents: Design, synthesis, structural insights and biological profile. Eur.J.Med.Chem., 178, 2019
6R83	CryoEM structure and molecular model of squid hemocyanin (Todarodes pacificus , TpH) 分子名称: Hemocyanin subunit 1 著者 Tanaka, Y, Kato, S, Stabrin, M, Raunser, S, Matsui, T, Gatsogiannis, C. 登録日 2019-03-31 公開日 2019-05-08 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (5.1 Å) 主引用文献 Cryo-EM reveals the asymmetric assembly of squid hemocyanin. Iucrj, 6, 2019

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