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7XJ3
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Structure of human TRPV3
分子名称: [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate, fusion of transient receptor potential cation channel subfamily V member 3 and 3C-GFP
著者Fan, J, Yue, Z, Jiang, D, Lei, X.
登録日2022-04-14
公開日2022-11-09
最終更新日2023-01-11
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Structural basis of TRPV3 inhibition by an antagonist.
Nat.Chem.Biol., 19, 2023
7XJ1
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Structure of human TRPV3_G573S in complex with Trpvicin in C2 symmetry
分子名称: Fusion protein of Transient receptor potential cation channel subfamily V member 3 and 3C-GFP, N-[5-[2-(2-cyanopropan-2-yl)pyridin-4-yl]-4-(trifluoromethyl)-1,3-thiazol-2-yl]-4,6-dimethoxy-pyrimidine-5-carboxamide, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate
著者Fan, J, Yue, Z, Jiang, D, Lei, X.
登録日2022-04-14
公開日2022-11-09
最終更新日2023-01-11
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Structural basis of TRPV3 inhibition by an antagonist.
Nat.Chem.Biol., 19, 2023
7XJ0
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Structure of human TRPV3 in complex with Trpvicin
分子名称: Fusion protein of Transient receptor potential cation channel subfamily V member 3 and 3C-GFP, N-[5-[2-(2-cyanopropan-2-yl)pyridin-4-yl]-4-(trifluoromethyl)-1,3-thiazol-2-yl]-4,6-dimethoxy-pyrimidine-5-carboxamide, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate
著者Fan, J, Yue, Z, Jiang, D, Lei, X.
登録日2022-04-14
公開日2022-11-09
最終更新日2023-01-11
実験手法ELECTRON MICROSCOPY (2.53 Å)
主引用文献Structural basis of TRPV3 inhibition by an antagonist.
Nat.Chem.Biol., 19, 2023
7UGG
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Cryo-EM structure of TRPV3 in complex with the anesthetic dyclonine
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Dyclonine, SODIUM ION, ...
著者Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I.
登録日2022-03-24
公開日2022-06-08
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Structural mechanism of TRPV3 channel inhibition by the anesthetic dyclonine.
Nat Commun, 13, 2022
7XCE
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Crystal structure of Ankyrin G in complex with neurofascin
分子名称: GLYCEROL, Neurofascin,Ankyrin-3, SULFATE ION
著者He, L, Li, J, Wang, C.
登録日2022-03-24
公開日2022-09-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of Ankyrin-G in complex with a fragment of Neurofascin reveals binding mechanisms required for integrity of the axon initial segment.
J.Biol.Chem., 298, 2022
7X6I
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Cryo-EM structure of the human TRPC5 ion channel in complex with G alpha i3 subunits, class1
分子名称: (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ...
著者Won, J, Jeong, H, Lee, H.H.
登録日2022-03-07
公開日2023-04-26
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (3.93 Å)
主引用文献Molecular architecture of the G alpha i -bound TRPC5 ion channel.
Nat Commun, 14, 2023
7X6C
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Cryo-EM structure of the human TRPC5 ion channel in lipid nanodiscs, class1
分子名称: (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, ...
著者Won, J, Jeong, H, Lee, H.H.
登録日2022-03-07
公開日2023-05-24
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Molecular architecture of the G alpha i -bound TRPC5 ion channel.
Nat Commun, 14, 2023
7TW3
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Cryo-EM structure of human ankyrin complex (B2P1A1) from red blood cell
分子名称: Ankyrin-1, Band 3 anion transport protein, Protein 4.2
著者Xia, X, Liu, S.H, Zhou, Z.H.
登録日2022-02-06
公開日2022-06-08
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structure, dynamics and assembly of the ankyrin complex on human red blood cell membrane.
Nat.Struct.Mol.Biol., 29, 2022
7TW5
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Cryo-EM structure of human ankyrin complex (B2P1A2) from red blood cell
分子名称: Ankyrin-1, Band 3 anion transport protein, Protein 4.2
著者Xia, X, Liu, S.H, Zhou, Z.H.
登録日2022-02-06
公開日2022-06-08
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Structure, dynamics and assembly of the ankyrin complex on human red blood cell membrane.
Nat.Struct.Mol.Biol., 29, 2022
7TW6
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Cryo-EM structure of human ankyrin complex (B4P1A1) from red blood cell
分子名称: Ankyrin-1, Band 3 anion transport protein, Protein 4.2
著者Xia, X, Liu, S.H, Zhou, Z.H.
登録日2022-02-06
公開日2022-06-08
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献Structure, dynamics and assembly of the ankyrin complex on human red blood cell membrane.
Nat.Struct.Mol.Biol., 29, 2022
7WSW
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BU of 7wsw by Molmil
Cryo-EM structure of the Potassium channel AKT1 from Arabidopsis thaliana
分子名称: PHOSPHATIDYLETHANOLAMINE, POTASSIUM ION, Potassium channel AKT1
著者Yang, G.H, Lu, Y.M, Zhang, Y.M, Jia, Y.T, Li, X.M, Lei, J.L.
登録日2022-02-02
公開日2022-11-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for the activity regulation of a potassium channel AKT1 from Arabidopsis.
Nat Commun, 13, 2022
7WM1
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Cryo-EM structure of AKT1-AtKC1
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium channel AKT1, ...
著者Dongliang, L, Zijie, Z, Yannan, Q, Yuyue, T, Huaizong, S.
登録日2022-01-14
公開日2023-01-25
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for the regulation mechanism of a hyper polarization-activated K+ channel AKT1 by AtKC1
To Be Published
7WM2
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Cryo-EM structure of AKT1
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium channel AKT1
著者Dongliang, L, Zijie, Z, Yannan, Q, Yuyue, T, Huaizong, S.
登録日2022-01-14
公開日2023-01-25
実験手法ELECTRON MICROSCOPY (2.69 Å)
主引用文献Structural basis for the regulation mechanism of a hyperpolarization-activated K+ channel AKT1 by AtKC1
To Be Published
7WDB
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Human TRPC5 channel in complex with riluzole
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine, CALCIUM ION, ...
著者Chen, L, Wei, M, Yang, Y.
登録日2021-12-21
公開日2022-04-13
最終更新日2022-08-03
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Structural identification of riluzole-binding site on human TRPC5.
Cell Discov, 8, 2022
7T6O
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BU of 7t6o by Molmil
Cryo-EM structure of TRPV5 in nanodiscs at pH6 state 3
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6Q
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BU of 7t6q by Molmil
Cryo-EM structure of TRPV5 T709D with PI(4,5)P2 in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6M
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BU of 7t6m by Molmil
Cryo-EM structure of TRPV5 in nanodiscs with PI(4,5)P2 at pH6 state 1
分子名称: Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6N
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BU of 7t6n by Molmil
Cryo-EM structure of TRPV5 in nanodiscs at pH6 state 2
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6K
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BU of 7t6k by Molmil
Cryo-EM structure of TRPV5 at pH6 in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6J
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BU of 7t6j by Molmil
Cryo-EM structure of TRPV5 at pH8 in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6L
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BU of 7t6l by Molmil
Cryo-EM structure of TRPV5 at pH5 in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6R
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BU of 7t6r by Molmil
Cryo-EM structure of TRPV5 T709D in nanodiscs in the presence of Calmodulin
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6P
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BU of 7t6p by Molmil
Cryo-EM structure of TRPV5 T709D in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T4X
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AKT1 K+ channel from A. thaliana in MSP2N2 lipid nanodisc
分子名称: PHOSPHATIDYLETHANOLAMINE, POTASSIUM ION, Potassium channel AKT1
著者Dickinson, M.S, Pourmal, S.
登録日2021-12-10
公開日2021-12-22
最終更新日2022-10-26
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Symmetry Reduction in a Hyperpolarization-Activated Homotetrameric Ion Channel.
Biochemistry, 61, 2022
7PTY
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Delta-latroinsectotoxin dimer
分子名称: Delta-latroinsectotoxin-Lt1a
著者Chen, M, Gatsogiannis, C.
登録日2021-09-27
公開日2021-12-08
実験手法ELECTRON MICROSCOPY (4.63 Å)
主引用文献Molecular architecture of black widow spider neurotoxins.
Nat Commun, 12, 2021

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件を2024-06-12に公開中

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