7N1R
 
 | | A novel and unique ATP hydrolysis to AMP by a human Hsp70 BiP | | 分子名称: | ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, Endoplasmic reticulum chaperone BiP, ... | | 著者 | Yang, J, Musayev, F, Liu, Q. | | 登録日 | 2021-05-28 | | 公開日 | 2022-01-12 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | A novel and unique ATP hydrolysis to AMP by a human Hsp70 Binding immunoglobin protein (BiP).
Protein Sci., 31, 2022
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4JLP
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4FF9
 | | Crystal Structure of cysteinylated WT SOD1. | | 分子名称: | COPPER (II) ION, CYSTEINE, Superoxide dismutase [Cu-Zn], ... | | 著者 | Auclair, J.R, Brodkin, H.R, D'Aquino, J.A, Ringe, D, Petsko, G.A, Agar, J.N. | | 登録日 | 2012-05-31 | | 公開日 | 2013-09-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5003 Å) | | 主引用文献 | Structural consequences of cysteinylation of cu/zn-superoxide dismutase.
Biochemistry, 52, 2013
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7N3M
 | | Co-complex CYP46A1 with 0431 (compound 17) | | 分子名称: | Cholesterol 24-hydroxylase, N,N-dimethyl-1-[4-(4-methyl-1H-pyrazol-1-yl)pyridin-3-yl]piperidine-4-carboxamide, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Lane, W, Yano, J. | | 登録日 | 2021-06-01 | | 公開日 | 2022-02-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | | 主引用文献 | Discovery of Novel 3-Piperidinyl Pyridine Derivatives as Highly Potent and Selective Cholesterol 24-Hydroxylase (CH24H) Inhibitors.
J.Med.Chem., 65, 2022
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4JL5
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7MPS
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7MQD
 | | Bartonella henselae NrnC complexed with pAGG. D4 symmetry. | | 分子名称: | NanoRNase C, RNA (5'-R(P*AP*GP*G)-3') | | 著者 | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | | 登録日 | 2021-05-05 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
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7MPR
 | | Brucella melitensis NrnC | | 分子名称: | NanoRNase C, SULFATE ION | | 著者 | Lormand, J.D, Sondermann, H. | | 登録日 | 2021-05-04 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
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7MQC
 | | Bartonella henselae NrnC bound to pGG. C1 reconstruction. | | 分子名称: | NanoRNase C, RNA (5'-R(P*GP*G)-3') | | 著者 | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | | 登録日 | 2021-05-05 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | | 主引用文献 | Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
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7MQI
 | | Bartonella henselae NrnC complexed with pAAAGG in the presence of Ca2+. C1 reconstruction. | | 分子名称: | NanoRNase C, RNA (5'-R(P*AP*AP*AP*GP*G)-3') | | 著者 | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | | 登録日 | 2021-05-05 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
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7MQF
 | | Bartonella henselae NrnC complexed with pAAAGG. D4 symmetry. | | 分子名称: | NanoRNase C, RNA (5'-R(P*AP*AP*AP*GP*G)-3') | | 著者 | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | | 登録日 | 2021-05-05 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | | 主引用文献 | Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
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7MQE
 | | Bartonella henselae NrnC complexed with pAGG. C1 reconstruction. | | 分子名称: | NanoRNase C, RNA (5'-R(P*AP*GP*G)-3') | | 著者 | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | | 登録日 | 2021-05-05 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.69 Å) | | 主引用文献 | Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
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7MQB
 | | Bartonella henselae NrnC bound to pGG. D4 Symmetry | | 分子名称: | NanoRNase C, RNA (5'-R(P*GP*G)-3') | | 著者 | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | | 登録日 | 2021-05-05 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
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7MQG
 | | Bartonella henselae NrnC complexed with pAAAGG. C1 reconstruction. | | 分子名称: | NanoRNase C, RNA (5'-R(P*AP*AP*AP*GP*G)-3') | | 著者 | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | | 登録日 | 2021-05-05 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
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7MQH
 | | Bartonella henselae NrnC complexed with pAAAGG in the presence of Ca2+. D4 Symmetry. | | 分子名称: | NanoRNase C, RNA (5'-R(P*AP*AP*AP*GP*G)-3') | | 著者 | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | | 登録日 | 2021-05-05 | | 公開日 | 2021-09-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
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7MKJ
 | | Cryo-EM structure of Escherichia coli RNA polymerase bound to T7A1 promoter DNA | | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Saecker, R.M, Darst, S.A, Chen, J. | | 登録日 | 2021-04-23 | | 公開日 | 2021-09-29 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7MKD
 | | Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 1) | | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Saecker, R.M, Darst, S.A, Chen, J. | | 登録日 | 2021-04-23 | | 公開日 | 2021-09-29 | | 最終更新日 | 2021-10-13 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7N3L
 | | Co-complex CYP46A1 with 0420 (compound 6) | | 分子名称: | 1,2-ETHANEDIOL, Cholesterol 24-hydroxylase, GLYCEROL, ... | | 著者 | Lane, W, Yano, J. | | 登録日 | 2021-06-01 | | 公開日 | 2022-02-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.631 Å) | | 主引用文献 | Discovery of Novel 3-Piperidinyl Pyridine Derivatives as Highly Potent and Selective Cholesterol 24-Hydroxylase (CH24H) Inhibitors.
J.Med.Chem., 65, 2022
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8RDZ
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3J9U
 | | Yeast V-ATPase state 2 | | 分子名称: | V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | | 著者 | Zhao, J, Benlekbir, S, Rubinstein, J.L. | | 登録日 | 2015-02-23 | | 公開日 | 2015-05-13 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | | 主引用文献 | Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase.
Nature, 521, 2015
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4PL4
 | | Crystal structure of murine IRE1 in complex with OICR464 inhibitor | | 分子名称: | 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, 2-methoxy-6-methyl-4-(4-methyl-3,4-dihydro-2H-1,4-benzoxazin-7-yl)phenol, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Sanches, M, Duffy, N, Talukdar, M, Thevakumaran, N, Chiovitti, D, Al-awar, R, Patterson, J.B, Sicheri, F. | | 登録日 | 2014-05-16 | | 公開日 | 2014-09-03 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure and mechanism of action of the hydroxy-aryl-aldehyde class of IRE1 endoribonuclease inhibitors.
Nat Commun, 5, 2014
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4PO2
 | | Crystal Structure of the Stress-Inducible Human Heat Shock Protein HSP70 Substrate-Binding Domain in Complex with Peptide Substrate | | 分子名称: | HSP70 substrate peptide, Heat shock 70 kDa protein 1A/1B, PHOSPHATE ION, ... | | 著者 | Zhang, P, Leu, J.I, Murphy, M.E, George, D.L, Marmorstein, R. | | 登録日 | 2014-02-24 | | 公開日 | 2014-08-20 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the stress-inducible human heat shock protein 70 substrate-binding domain in complex with Peptide substrate.
Plos One, 9, 2014
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7N4E
 | | Escherichia coli sigma 70-dependent paused transcription elongation complex | | 分子名称: | 5'-R(*UP*UP*CP*GP*GP*AP*GP*AP*GP*GP*UP*A)-3', DNA (61-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Molodtsov, V, Su, M, Ebright, R.H. | | 登録日 | 2021-06-04 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural and mechanistic basis of sigma-dependent transcriptional pausing.
Proc.Natl.Acad.Sci.USA, 119, 2022
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8Y0W
 | | dormant ribosome with eIF5A, eEF2 and SERBP1 | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | 著者 | Du, M, Zeng, F. | | 登録日 | 2024-01-23 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-08-21 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Implication of Stm1 in the protection of eIF5A, eEF2 and tRNA through dormant ribosomes.
Front Mol Biosci, 11, 2024
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4PPR
 | | Crystal structure of Mycobacterium tuberculosis D,D-peptidase Rv3330 in complex with meropenem | | 分子名称: | (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid, Penicillin-binding protein DacB1 | | 著者 | Prigozhin, D.M, Huizar, J.P, Mavrici, D, Alber, T, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2014-02-27 | | 公開日 | 2014-11-05 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Subfamily-specific adaptations in the structures of two penicillin-binding proteins from Mycobacterium tuberculosis.
Plos One, 9, 2014
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