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2VR6
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BU of 2vr6 by Molmil
Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.3 A resolution
分子名称: COPPER (II) ION, SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ...
著者Antonyuk, S, Cao, X, Seetharaman, S.V, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Selverstone Valentine, J, Hasnain, S.S, Hart, P.J.
登録日2008-03-28
公開日2008-04-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structures of the G85R Variant of Sod1 in Familial Amyotrophic Lateral Sclerosis.
J.Biol.Chem., 283, 2008
1KNY
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BU of 1kny by Molmil
KANAMYCIN NUCLEOTIDYLTRANSFERASE
分子名称: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, KANAMYCIN A, KANAMYCIN NUCLEOTIDYLTRANSFERASE, ...
著者Pedersen, L.C, Benning, M.M, Holden, H.M.
登録日1995-07-07
公開日1996-08-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural investigation of the antibiotic and ATP-binding sites in kanamycin nucleotidyltransferase.
Biochemistry, 34, 1995
2VEZ
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BU of 2vez by Molmil
AfGNA1 crystal structure complexed with Acetyl-CoA and Glucose-6P gives new insights into catalysis
分子名称: 6-O-phosphono-alpha-D-glucopyranose, ACETYL COENZYME *A, PHOSPHATE ION, ...
著者Hurtado-Guerrero, R, Raimi, O, Shepherd, S, van Aalten, D.M.F.
登録日2007-10-27
公開日2009-03-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Glucose-6-Phosphate as a Probe for the Glucosamine- 6-Phosphate N-Acetyltransferase Michaelis Complex.
FEBS Lett., 581, 2007
4W7I
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BU of 4w7i by Molmil
Crystal structure of DEH reductase A1-R' mutant
分子名称: 4-deoxy-L-erythro-5-hexoseulose uronate reductase A1-R'
著者Takase, R, Mikami, B, Kawai, S, Murata, K, Hashimoto, W.
登録日2014-08-22
公開日2014-09-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structure-based Conversion of the Coenzyme Requirement of a Short-chain Dehydrogenase/Reductase Involved in Bacterial Alginate Metabolism.
J.Biol.Chem., 289, 2014
2V82
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BU of 2v82 by Molmil
KDPGal complexed to KDPGal
分子名称: 2-DEHYDRO-3-DEOXY-6-PHOSPHOGALACTONATE ALDOLASE, 2-KETO-DEOXY-GALACTOSE
著者Naismith, J.H.
登録日2007-08-02
公開日2007-08-14
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Characterization and crystal structure of Escherichia coli KDPGal aldolase.
Bioorg. Med. Chem., 16, 2008
1KAN
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BU of 1kan by Molmil
MOLECULAR STRUCTURE OF KANAMYCIN NUCLEOTIDYLTRANSFERASE DETERMINED TO 3.0-ANGSTROMS RESOLUTION
分子名称: KANAMYCIN NUCLEOTIDYLTRANSFERASE
著者Holden, H.M, Rayment, I, Sakon, J.
登録日1993-08-13
公開日1994-08-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular structure of kanamycin nucleotidyltransferase determined to 3.0-A resolution.
Biochemistry, 32, 1993
2V4Y
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BU of 2v4y by Molmil
THE STRUCTURE OF E. COLI UMP KINASE IN COMPLEX WITH ITS ALLOSTERIC REGULATOR GTP
分子名称: GUANOSINE-5'-TRIPHOSPHATE, URIDYLATE KINASE
著者Meyer, P, Evrin, C, Briozzo, P, Joly, N, Barzu, O, Gilles, A.M.
登録日2008-09-30
公開日2008-10-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and Functional Characterization of Escherichia Coli Ump Kinase in Complex with its Allosteric Regulator GTP.
J.Biol.Chem., 283, 2008
4W90
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BU of 4w90 by Molmil
Crystal structure of Bacillus subtilis cyclic-di-AMP riboswitch ydaO
分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A, ...
著者Jones, C.P, Ferre-D'Amare, A.R.
登録日2014-08-26
公開日2014-10-15
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.118 Å)
主引用文献Crystal structure of a c-di-AMP riboswitch reveals an internally pseudo-dimeric RNA.
Embo J., 33, 2014
4LJZ
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BU of 4ljz by Molmil
Crystal Structure Analysis of the E.coli holoenzyme
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Bae, B, Darst, S.A.
登録日2013-07-05
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.5871 Å)
主引用文献Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
2UW3
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BU of 2uw3 by Molmil
Structure of PKA-PKB chimera complexed with 5-methyl-4-phenyl-1H- pyrazole
分子名称: 3-METHYL-4-PHENYL-1H-PYRAZOLE, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA, CAMP-DEPENDENT PROTEIN KINASE, ...
著者Davies, T.G, Saxty, G, Woodhead, S.J, Berdini, V, Verdonk, M.L, Wyatt, P.G, Boyle, R.G, Barford, D, Downham, R, Garrett, M.D, Carr, R.A.
登録日2007-03-19
公開日2007-05-08
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Identification of Inhibitors of Protein Kinase B Using Fragment-Based Lead Discovery
J.Med.Chem., 50, 2007
2I9H
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BU of 2i9h by Molmil
NMR solution structure of the reduced form of thioredoxin 1 from yeast (Trx1)
分子名称: Thioredoxin I
著者Pinheiro, A.S, Amorim, G.C, Almeida, F.C.L, Valente, A.P.
登録日2006-09-05
公開日2007-07-17
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献NMR solution structure of the reduced form of thioredoxin 1 from Sacharomyces cerevisiae
Proteins, 70, 2008
4LK9
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BU of 4lk9 by Molmil
Crystal Structure of MOZ double PHD finger histone H3 tail complex
分子名称: Histone H3.1, Histone acetyltransferase KAT6A, ZINC ION
著者Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M.
登録日2013-07-07
公開日2013-10-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.
Nucleic Acids Res., 42, 2014
4UZ5
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BU of 4uz5 by Molmil
STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM IV - 2.1A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, NOTUM
著者Zebisch, M, Jones, E.Y.
登録日2014-09-04
公開日2015-02-25
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
4WE1
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BU of 4we1 by Molmil
Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)-2-naphthonitrile (JLJ600)
分子名称: 5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}naphthalene-2-carbonitrile, Gag-Pol polyprotein, MAGNESIUM ION, ...
著者Frey, K.M, Anderson, K.S.
登録日2014-09-09
公開日2014-12-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.491 Å)
主引用文献Picomolar Inhibitors of HIV-1 Reverse Transcriptase: Design and Crystallography of Naphthyl Phenyl Ethers.
Acs Med.Chem.Lett., 5, 2014
4LKT
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BU of 4lkt by Molmil
Crystal Structure of Human Epidermal Fatty Acid Binding Protein (FABP5) in Complex with Linoleic Acid
分子名称: AMMONIUM ION, CHLORIDE ION, CITRIC ACID, ...
著者Armstrong, E.H, Ortlund, E.A.
登録日2013-07-08
公開日2014-03-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor beta / delta (FABP5-PPAR beta / delta ) signaling pathway.
J.Biol.Chem., 289, 2014
2VCY
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BU of 2vcy by Molmil
Crystal Structure of 2-Enoyl Thioester Reductase of Human FAS II
分子名称: SULFATE ION, TRANS-2-ENOYL-COA REDUCTASE
著者Haapalainen, A.M, Pudas, R, Smart, O.S, Wierenga, R.K.
登録日2007-09-28
公開日2008-06-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Structural Enzymological Studies of 2-Enoyl Thioester Reductase of the Human Mitochondrial Fas II Pathway: New Insights Into its Substrate Recognition Properties.
J.Mol.Biol., 379, 2008
2V9W
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BU of 2v9w by Molmil
Complex structure of Sulfolobus solfataricus DPO4 and DNA duplex containing a hydrophobic thymine isostere 2,4-difluorotoluene nucleotide in the template strand
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *CP*TP*G)-3', 5'-D(*TP*TP*CP*AP*GP*DFTP*AP*GP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ...
著者Irimia, A, Pallan, P.S, Egli, M.
登録日2007-08-27
公開日2007-10-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and Activity of Y-Class DNA Polymerase Dpo4 from Sulfolobus Solfataricus with Templates Containing the Hydrophobic Thymine Analog 2,4-Difluorotoluene.
J.Biol.Chem., 282, 2007
2IJ9
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BU of 2ij9 by Molmil
Crystal Structure of Uridylate Kinase from Archaeoglobus Fulgidus
分子名称: SULFATE ION, Uridylate kinase
著者Patskovsky, Y, Chen, R, Keefe, L.J, Sauder, J.M, Dickey, M, Adams, J.M, Ozyurt, S, Wasserman, S.R, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2006-09-29
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structure of Uridylate Kinase from Archaeoglobus Fulgidus
To be Published
8DEA
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BU of 8dea by Molmil
Scaffold Hopping via Ring Opening Enables Identification of Acyclic Compounds as New Complement Factor D Inhibitors
分子名称: 1-[(3-acetylphenyl)acetyl]-N-(6-bromopyridin-2-yl)-L-prolinamide, Complement factor D, GLYCEROL
著者Raman, K, Babu, Y.S.
登録日2022-06-20
公開日2022-11-02
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.214 Å)
主引用文献Scaffold hopping via ring opening enables identification of acyclic compounds as new complement Factor D inhibitors.
Bioorg.Med.Chem., 74, 2022
2IPA
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BU of 2ipa by Molmil
solution structure of Trx-ArsC complex
分子名称: Protein arsC, Thioredoxin
著者Jin, C, Hu, Y, Li, Y, Zhang, X.
登録日2006-10-12
公開日2007-02-13
最終更新日2024-11-13
実験手法SOLUTION NMR
主引用文献Conformational fluctuations coupled to the thiol-disulfide transfer between thioredoxin and arsenate reductase in Bacillus subtilis.
J.Biol.Chem., 282, 2007
2V2S
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BU of 2v2s by Molmil
Mutant R59M recombinant horse spleen apoferritin crystallized in acidic conditions
分子名称: CADMIUM ION, FERRITIN LIGHT CHAIN, GLYCEROL, ...
著者De Val, N, Declercq, J.P.
登録日2007-06-06
公開日2008-06-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Structural Analysis of Haemin Demetallation by L-Chain Apoferritins
J.Inorg.Biochem., 112, 2012
1LIF
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BU of 1lif by Molmil
THE ADIPOCYTE LIPID-BINDING PROTEIN AT 1.6 ANGSTROMS RESOLUTION: CRYSTAL STRUCTURES OF THE APOPROTEIN AND WITH BOUND SATURATED AND UNSATURATED FATTY ACIDS
分子名称: ADIPOCYTE LIPID-BINDING PROTEIN, STEARIC ACID
著者Zu, Z, Bernlohr, D.A, Banaszak, L.J.
登録日1993-12-21
公開日1994-04-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The adipocyte lipid-binding protein at 1.6-A resolution. Crystal structures of the apoprotein and with bound saturated and unsaturated fatty acids.
J.Biol.Chem., 268, 1993
4LG4
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BU of 4lg4 by Molmil
Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5
分子名称: GLYCEROL, Serine/threonine-protein kinase 3
著者Luo, X, Ni, L, Tomchick, D.R.
登録日2013-06-27
公開日2013-09-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5.
Structure, 21, 2013
2V2O
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Mutant R59M recombinant horse spleen apoferritin cocrystallized with haemin in basic conditions
分子名称: CADMIUM ION, FERRITIN LIGHT CHAIN, GLYCEROL, ...
著者De Val, N, Declercq, J.P.
登録日2007-06-06
公開日2008-06-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural Analysis of Haemin Demetallation by L-Chain Apoferritins
J.Inorg.Biochem., 112, 2012
2V32
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Crystal Structure of the C45S mutant of the Peroxiredoxin 6 of Arenicola Marina. Monoclinic form 2
分子名称: BENZOIC ACID, PEROXIREDOXIN 6
著者Smeets, A, Declercq, J.P.
登録日2007-06-11
公開日2008-04-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Crystal Structure of the C45S Mutant of Annelid Arenicola Marina Peroxiredoxin 6 Supports its Assignment to the Mechanistically Typical 2-Cys Subfamily without Any Formation of Toroid-Shaped Decamers.
Protein Sci., 17, 2008

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