2VCY

Crystal Structure of 2-Enoyl Thioester Reductase of Human FAS II

Summary for 2VCY

• Entry DOI: 10.2210/pdb2vcy/pdb
• Related: 1ZSY
• Descriptor: TRANS-2-ENOYL-COA REDUCTASE, SULFATE ION (3 entities in total)
• Functional Keywords: nadp, polymorphism, mitochondrion, oxidoreductase, fatty acid biosynthesis, enoyl thioester reductase, lipid synthesis, transit peptide
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 2
• Total formula weight: 75500.41

Authors

Haapalainen, A.M.,Pudas, R.,Smart, O.S.,Wierenga, R.K. (deposition date: 2007-09-28, release date: 2008-06-03, Last modification date: 2023-12-13)

• Primary citation: Chen, Z.J.,Pudas, R.,Sharma, S.,Smart, O.S.,Juffer, A.H.,Hiltunen, J.K.,Wierenga, R.K.,Haapalainen, A.M.; Structural Enzymological Studies of 2-Enoyl Thioester Reductase of the Human Mitochondrial Fas II Pathway: New Insights Into its Substrate Recognition Properties.; J.Mol.Biol., 379:830-, 2008; PubMed: 18479707; DOI: 10.1016/J.JMB.2008.04.041

Experimental method

X-RAY DIFFRACTION (2.41 Å)