PDB: 30476 件ウェブページステータス検索Chemie searchBIRD

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5Z8R	BRD4 Bromodomain 1 with an inhibitor 分子名称: 1-ethyl-6-[(3S)-3-oxidanylpiperidin-1-yl]sulfonyl-benzo[cd]indol-2-one, Bromodomain-containing protein 4 著者 Xiao, S, Chen, S, Chen, H. 登録日 2018-02-01 公開日 2019-02-06 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 BRD4 Bromodomain 1 with an inhibitor To Be Published
4YOO	p107 pocket domain in complex with LIN52 P29A peptide 分子名称: LIN52 peptide, Retinoblastoma-like protein 1,Retinoblastoma-like protein 1, SULFATE ION 著者 Guiley, K.Z, Liban, T.J, Felthousen, J.G, Ramanan, P, Tripathi, S, Litovchick, L, Rubin, S.M. 登録日 2015-03-12 公開日 2015-05-13 最終更新日 2019-12-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural mechanisms of DREAM complex assembly and regulation. Genes Dev., 29, 2015
4YP0	Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with 5-aminoisoquinoline (Chem 79) 分子名称: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, HISTIDINE, ... 著者 Koh, C.-Y, Hol, W.G.J. 登録日 2015-03-12 公開日 2015-08-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
5ZEH	Crystal structure of Entamoeba histolytica Arginase in complex with L- Ornithine at 2.35 A 分子名称: 1,2-ETHANEDIOL, Arginase, L-ornithine, ... 著者 Malik, A, Dalal, V, Ankri, S, Tomar, S. 登録日 2018-02-27 公開日 2019-06-26 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Structural insights into Entamoeba histolytica arginase and structure-based identification of novel non-amino acid based inhibitors as potential antiamoebic molecules. Febs J., 286, 2019
4YAT	Crystal structure of TRIM24 PHD-bromodomain complexed with N-(1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl)-4-methoxybenzene-1-sulfonamide (5b) 分子名称: N-(1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-4-methoxybenzenesulfonamide, Transcription intermediary factor 1-alpha, ZINC ION 著者 Poncet-Montange, G, Palmer, W, Jones, P. 登録日 2015-02-17 公開日 2015-06-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor. J.Med.Chem., 59, 2016
4YB8	Ca. Korarchaeum cryptofilum dinucleotide forming Acetyl-coenzyme A synthetase 1 in complex with phosphate and ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Weisse, R.H.-J, Scheidig, A.J. 登録日 2015-02-18 公開日 2016-01-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of NDP-forming Acetyl-CoA synthetase ACD1 reveals a large rearrangement for phosphoryl transfer. Proc.Natl.Acad.Sci.USA, 113, 2016
4YC6	CDK1/CKS1 分子名称: Cyclin-dependent kinase 1, Cyclin-dependent kinases regulatory subunit 1 著者 Brown, N.R, Korolchuk, S, Martin, M.P, Stanley, W, Moukhametzianov, R, Noble, M.E.M, Endicott, J.A. 登録日 2015-02-19 公開日 2015-05-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 CDK1 structures reveal conserved and unique features of the essential cell cycle CDK. Nat Commun, 6, 2015
4YRE	Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with (2-bromophenyl)methanol (Chem 145) 分子名称: (2-bromophenyl)methanol, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... 著者 Koh, C.-Y, Hol, W.G.J. 登録日 2015-03-15 公開日 2015-08-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4YDD	Crystal structure of the perchlorate reductase PcrAB from Azospira suillum PS 分子名称: 1,2-ETHANEDIOL, 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, DI(HYDROXYETHYL)ETHER, ... 著者 Tsai, C.-L, Youngblut, M.D, Tainer, J.A. 登録日 2015-02-21 公開日 2016-03-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Perchlorate Reductase Is Distinguished by Active Site Aromatic Gate Residues. J.Biol.Chem., 291, 2016
5ZMI	Crystal structure of APRT from Y. pseudotuberculosis in complex with adenine. 分子名称: ADENINE, Adenine phosphoribosyltransferase, SODIUM ION 著者 Pavithra, G.C, Fox, G.C, Ramagopal, U.A. 登録日 2018-04-03 公開日 2019-04-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal structure of adenine phosphoribosyltransferase from Yersinia pseudotuberculosis To be published
5ZIC	Crystal structure of human GnT-V luminal domain in complex with acceptor sugar 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-6-thio-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose, Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A 著者 Nagae, M, Yamaguchi, Y. 登録日 2018-03-14 公開日 2018-08-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and mechanism of cancer-associated N-acetylglucosaminyltransferase-V. Nat Commun, 9, 2018
5YUM	Crystallographic structures of IlvN.Val/Ile complexes:Conformational selectivity for feedback inhibition of AHASs 分子名称: Acetolactate synthase isozyme 1 small subunit, COBALT (II) ION, ISOLEUCINE 著者 Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B. 登録日 2017-11-22 公開日 2018-09-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.432 Å) 主引用文献 Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases. Biochemistry, 58, 2019
4YLM	Structure of PvcB, an Fe, alpha-ketoglutarate dependent oxygenase from an isonitrile synthetic pathway 分子名称: GLYCEROL, Pyoverdine biosynthesis protein PvcB 著者 Zhu, J, Lippa, G.M, Gulick, A.M, Tipton, P.A. 登録日 2015-03-05 公開日 2015-04-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Examining Reaction Specificity in PvcB, a Source of Diversity in Isonitrile-Containing Natural Products. Biochemistry, 54, 2015
4YLT	Crystal structure of beta-ketoacyl-ACP synthase III (FabH) from Yersinia pestis 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 3 著者 Nanson, J.D, Forwood, J.K. 登録日 2015-03-05 公開日 2015-04-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Characterisation of the Beta-Ketoacyl-Acyl Carrier Protein Synthases, FabF and FabH, of Yersinia pestis. Sci Rep, 5, 2015
4YM1	Crystal structure of the human galectin-4 C-terminal carbohydrate recognition domain in complex with 2'-fucosyllactose 分子名称: Galectin-4, SULFATE ION, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose 著者 Bum-Erdene, K, Blanchard, H. 登録日 2015-03-06 公開日 2015-07-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural characterization of human galectin-4 C-terminal domain: elucidating the molecular basis for recognition of glycosphingolipids, sulfated saccharides and blood group antigens. Febs J., 282, 2015
5ZB0	Crystal structure of thymidylate kinase in complex with ADP and TDP from thermus thermophilus HB8 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... 著者 Chaudhary, S.K, Jeyakanthan, J, Sekar, K. 登録日 2018-02-09 公開日 2018-12-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.19 Å) 主引用文献 Insights into product release dynamics through structural analyses of thymidylate kinase. Int. J. Biol. Macromol., 123, 2018
5ZBU	Crystal Structure of PA-TM-RING E3 ligase RNF13 RING domain in complex with E2~Ub 分子名称: E3 ubiquitin-protein ligase RNF13, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2, ... 著者 Datta, A.B, Sarkar, S. 登録日 2018-02-12 公開日 2019-02-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal Structure of PA-TM-RING E3 ligase RNF13 RING domain in complex with E2~Ub To Be Published
4YPQ	Crystal structure of the ROR(gamma)t ligand binding domain in complex with 4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-1H-indazol-3-yl)benzoic acid 分子名称: 4-{1-[2-chloro-6-(trifluoromethyl)benzoyl]-1H-indazol-3-yl}benzoic acid, MAGNESIUM ION, Nuclear receptor ROR-gamma 著者 Leysen, S, Scheepstra, M, van Almen, G.C, Ottmann, C, Brunsveld, L. 登録日 2015-03-13 公開日 2015-12-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Identification of an allosteric binding site for ROR gamma t inhibition. Nat Commun, 6, 2015
4Z3P	MATE transporter ClbM in complex with Rb+ 分子名称: CACODYLATE ION, Putative drug/sodium antiporter, RUBIDIUM ION 著者 Mousa, J.J, Bruner, S.D. 登録日 2015-03-31 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 MATE transport of the E. coli-derived genotoxin colibactin. Nat Microbiol, 1, 2016
4Z47	Structure of the enzyme-product complex resulting from TDG action on a GU mismatch in the presence of excess base 分子名称: 1,2-ETHANEDIOL, ACETIC ACID, DNA, ... 著者 Pozharski, E, Malik, S.S, Drohat, A.C. 登録日 2015-04-01 公開日 2015-09-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA. Nucleic Acids Res., 43, 2015
5ZJN	Structure of N-acetylmannosamine-6-phosphate-2-epimerase from Vibrio cholerae with N-acetylmannosamine-6-phosphate 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, N-acetylmannosamine-6-phosphate, ... 著者 Manjunath, L, Guntupalli, S. 登録日 2018-03-21 公開日 2018-09-19 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Crystal structures and kinetic analyses of N-acetylmannosamine-6-phosphate 2-epimerases from Fusobacterium nucleatum and Vibrio cholerae Acta Crystallogr F Struct Biol Commun, 74, 2018
4Z7H	Crystal structure of human IRE1 cytoplasmic kinase-RNase region - complex with imidazopyridine compound 3 分子名称: 2-methoxy-4-[6-(propan-2-ylamino)imidazo[1,2-b]pyridazin-3-yl]benzamide, SULFATE ION, Serine/threonine-protein kinase/endoribonuclease IRE1 著者 Joshi, A, Bayliss, R. 登録日 2015-04-07 公開日 2015-05-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Molecular mechanisms of human IRE1 activation through dimerization and ligand binding. Oncotarget, 6, 2015
4Z4L	Crystal Structure of cellobiose 2-epimerase from Caldicellulosiruptor saccharolyticus DSM 8903 分子名称: 1,2-ETHANEDIOL, Cellobiose 2-epimerase 著者 Shen, Q.Y, Zhang, Y.Z. 登録日 2015-04-02 公開日 2016-04-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.671 Å) 主引用文献 Crystal Structure of cellobiose 2-epimerase from Caldicellulosiruptor saccharolyticus DSM 8903 to be published
4YXA	Complex of SpaO(SPOA1,2 SeMet) and OrgB(APAR)::T4lysozyme fusion protein 分子名称: Oxygen-regulated invasion protein OrgB,Endolysin, Surface presentation of antigens protein SpaO 著者 Notti, R.Q, Stebbins, C.E. 登録日 2015-03-22 公開日 2015-06-03 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 A common assembly module in injectisome and flagellar type III secretion sorting platforms. Nat Commun, 6, 2015
4YXT	PksG, a HMG-CoA Synthase from Bacillus subtilus 分子名称: Polyketide biosynthesis 3-hydroxy-3-methylglutaryl-ACP synthase PksG 著者 Till, M, Nair, A.V, Robson, A, Race, P.R. 登録日 2015-03-23 公開日 2016-06-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 PksG, a HMG-CoA Synthase from Bacillus subtilus To Be Published

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