PDB: 5653 件ウェブページステータス検索Chemie searchBIRD

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6UU4	E. coli sigma-S transcription initiation complex with a 3-nt RNA ("old" crystal soaked with GTP and dinucleotide GpA for 30 minutes) 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Zuo, Y, De, S, Steitz, T.A. 登録日 2019-10-30 公開日 2020-08-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.305 Å) 主引用文献 Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UU7	E. coli sigma-S transcription initiation complex with a 6-nt RNA and an NTP ("Old" crystal soaked with UTP, CTP, ddGTP, and dinucleotide ApG for 30 minutes) 分子名称: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Zuo, Y, De, S, Steitz, T.A. 登録日 2019-10-30 公開日 2020-08-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.4 Å) 主引用文献 Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UUC	E. coli sigma-S transcription initiation complex with a 3-nt RNA and a mismatching ATP ("Fresh" crystal soaked with ATP for 2 hours) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Zuo, Y, De, S, Steitz, T.A. 登録日 2019-10-30 公開日 2020-08-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.096 Å) 主引用文献 Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UU5	E. coli sigma-S transcription initiation complex with a 6-nt RNA ("Old" crystal soaked with GTP, UTP, CTP, and dinucleotide GpA for 30 minutes) 分子名称: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Zuo, Y, De, S, Steitz, T.A. 登録日 2019-10-30 公開日 2020-08-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (5.403 Å) 主引用文献 Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
8AP1	Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with two GTP molecules poised for de novo initiation (IC2) 分子名称: DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Goovaerts, Q, Shen, J, Patel, S.S, Das, K. 登録日 2022-08-09 公開日 2023-08-23 最終更新日 2023-11-01 実験手法 ELECTRON MICROSCOPY (3.47 Å) 主引用文献 Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622, 2023
6KOS	Crystal structure of SUWA (Super WA20), a hyper-stable de novo protein with a dimeric bisecting topology 分子名称: SUWA (Super WA20) 著者 Kimura, N, Arai, R. 登録日 2019-08-13 公開日 2020-01-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 HyperstableDe NovoProtein with a Dimeric Bisecting Topology. Acs Synth Biol, 9, 2020
6EGM	Crystal Structure of a de novo Three-stranded Coiled Coil Peptide Containing D-Leu in a d-site Position of a Tris-thiolate Binding Site 分子名称: Apo-(GRAND CoilSerL16CL19(DLE))3, ZINC ION 著者 Ruckthong, L, Stuckey, J.A, Pecoraro, V.L. 登録日 2018-08-20 公開日 2019-04-03 最終更新日 2019-12-18 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 How Outer Coordination Sphere Modifications Can Impact Metal Structures in Proteins: A Crystallographic Evaluation. Chemistry, 25, 2019
7N1J	Crystal structure of FGFR4 domain 3 in complex with a de novo-designed mini-binder 分子名称: Binder, Fibroblast growth factor receptor 4 著者 Park, J.S, Lee, S. 登録日 2021-05-27 公開日 2022-04-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Design of protein-binding proteins from the target structure alone. Nature, 605, 2022
6GFW	Cryo-EM structure of bacterial RNA polymerase-sigma54 holoenzyme initial transcribing complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Glyde, R, Ye, F.Z, Zhang, X.D. 登録日 2018-05-02 公開日 2018-07-04 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structures of Bacterial RNA Polymerase Complexes Reveal the Mechanism of DNA Loading and Transcription Initiation. Mol. Cell, 70, 2018
1HQJ	CRYSTAL STRUCTURE OF A DE NOVO DESIGNED TRIMERIC COILED-COIL PEPTIDE 分子名称: LEAD (II) ION, SULFATE ION, ZJU-GLU-LEU-GLU-ALA-ARG-ILE-ARG-GLU-LEU-GLU-ALA-ARG-ILE-LYS-NH2 著者 Burkhard, P, Meier, M, Lustig, A. 登録日 2000-12-18 公開日 2001-03-14 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Design of a minimal protein oligomerization domain by a structural approach. Protein Sci., 9, 2000
6TMS	Crystal structure of a de novo designed hexameric helical-bundle protein 分子名称: SULFATE ION, a novel designed pore protein, affinity purification tag 著者 Xu, C, Pei, X.Y, Luisi, B.F, Baker, D. 登録日 2019-12-05 公開日 2020-04-29 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Computational design of transmembrane pores. Nature, 585, 2020
4GVW	Three-dimensional structure of the de novo designed serine hydrolase 2bfq_3, Northeast Structural Genomics Consortium (NESG) Target OR248 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETIC ACID, De novo designed serine hydrolase, ... 著者 Kuzin, A, Lew, S, Seetharaman, J, Rajagopalan, S, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) 登録日 2012-08-31 公開日 2012-09-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.113 Å) 主引用文献 Northeast Structural Genomics Consortium Target OR248 To be Published
8QNJ	Folded alpha helical de novo proteins from Apilactobacillus kunkeei 分子名称: Lenovo Protein 著者 Celestine, C. 登録日 2023-09-26 公開日 2024-02-21 最終更新日 2024-05-08 実験手法 SOLUTION NMR 主引用文献 Folded Alpha Helical Putative New Proteins from Apilactobacillus kunkeei. J.Mol.Biol., 436, 2024
4QBQ	Crystal structure of DNMT3a ADD domain bound to H3 peptide 分子名称: DNA (cytosine-5)-methyltransferase 3A, Histone H3, ZINC ION 著者 Li, H, Patel, D.J. 登録日 2014-05-08 公開日 2015-05-13 実験手法 X-RAY DIFFRACTION (2.406 Å) 主引用文献 Engineering of a histone-recognition domain in a de novo DNA methyltransferase alters the epigenetic landscape of ESCs To be Published
4QBS	Crystal structure of DNMT3a ADD domain E545R mutant bound to H3T3ph peptide 分子名称: DNA (cytosine-5)-methyltransferase 3A, Histone H3, SULFATE ION, ... 著者 Wang, H, Li, H. 登録日 2014-05-08 公開日 2015-05-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Engineering of a histone-recognition domain in a de novo DNA methyltransferase alters the epigenetic landscape of ESCs To be Published
4QBR	Crystal structure of DNMT3a ADD domain G550D mutant bound to H3 peptide 分子名称: DNA (cytosine-5)-methyltransferase 3A, Histone H3, ZINC ION 著者 Wang, H, Li, H. 登録日 2014-05-08 公開日 2015-05-13 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.902 Å) 主引用文献 Engineering of a histone-recognition domain in a de novo DNA methyltransferase alters the epigenetic landscape of ESCs To be Published
7BG1	Structure of anti-FLAG M2 Fab domain remodeled based on proteomic sequencing 分子名称: CHLORIDE ION, SULFATE ION, anti-FLAG M2 heavy chain, ... 著者 Pronker, M.F, Snijder, J. 登録日 2021-01-05 公開日 2021-07-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Mass Spectrometry-Based De Novo Sequencing of Monoclonal Antibodies Using Multiple Proteases and a Dual Fragmentation Scheme. J.Proteome Res., 20, 2021
3Q7W	Crystal structure of Symfoil-4P/PV1: de novo designed beta-trefoil architecture with symmetric primary structure, primitive version 1 分子名称: SULFATE ION, de novo designed beta-trefoil architecture with symmetric primary structure 著者 Blaber, M, Lee, J. 登録日 2011-01-05 公開日 2012-01-11 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Simplified protein design biased for prebiotic amino acids yields a foldable, halophilic protein. Proc.Natl.Acad.Sci.USA, 110, 2013
3O4C	Crystal structure of Symfoil-4V: de novo designed beta-trefoil architecture with symmetric primary structure 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, SULFATE ION, ... 著者 Lee, J, Blaber, M. 登録日 2010-07-26 公開日 2010-12-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Experimental support for the evolution of symmetric protein architecture from a simple peptide motif. Proc.Natl.Acad.Sci.USA, 108, 2011
3O4B	Crystal structure of Symfoil-4T: de novo designed beta-trefoil architecture with symmetric primary structure 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, SULFATE ION, ... 著者 Lee, J, Blaber, M. 登録日 2010-07-26 公開日 2010-12-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Experimental support for the evolution of symmetric protein architecture from a simple peptide motif. Proc.Natl.Acad.Sci.USA, 108, 2011
3O4A	Crystal structure of Symfoil-2: de novo designed beta-trefoil architecture with symmetric primary structure 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, de novo designed beta-trefoil architecture with symmetric primary structure 著者 Lee, J, Blaber, M. 登録日 2010-07-26 公開日 2010-12-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Experimental support for the evolution of symmetric protein architecture from a simple peptide motif. Proc.Natl.Acad.Sci.USA, 108, 2011
3O49	Crystal structure of Symfoil-1: de novo designed beta-trefoil architecture with symmetric primary structure 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, de novo designed beta-trefoil architecture with symmetric primary structure 著者 Lee, J, Blaber, M. 登録日 2010-07-26 公開日 2010-12-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Experimental support for the evolution of symmetric protein architecture from a simple peptide motif. Proc.Natl.Acad.Sci.USA, 108, 2011
3OL0	Crystal structure of Monofoil-4P homo-trimer: de novo designed monomer trefoil-fold sub-domain which forms homo-trimer assembly 分子名称: SULFATE ION, de novo designed monomer trefoil-fold sub-domain which forms homo-trimer assembly 著者 Lee, J, Blaber, M. 登録日 2010-08-25 公開日 2010-12-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.483 Å) 主引用文献 Experimental support for the evolution of symmetric protein architecture from a simple peptide motif. Proc.Natl.Acad.Sci.USA, 108, 2011
3OGF	Crystal structure of Difoil-4P homo-trimer: de novo designed dimeric trefoil-fold sub-domain which forms homo-trimer assembly 分子名称: SULFATE ION, de novo designed dimeric trefoil-fold sub-domain which forms homo-trimer assembly 著者 Lee, J, Blaber, M. 登録日 2010-08-16 公開日 2010-12-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.864 Å) 主引用文献 Experimental support for the evolution of symmetric protein architecture from a simple peptide motif. Proc.Natl.Acad.Sci.USA, 108, 2011
3O4D	Crystal structure of Symfoil-4P: de novo designed beta-trefoil architecture with symmetric primary structure 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, SULFATE ION, ... 著者 Lee, J, Blaber, M. 登録日 2010-07-26 公開日 2010-12-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Experimental support for the evolution of symmetric protein architecture from a simple peptide motif. Proc.Natl.Acad.Sci.USA, 108, 2011

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