2RBX
| Cytochrome C Peroxidase W191G in complex with pyrimidine-2,4,6-triamine. | 分子名称: | Cytochrome C Peroxidase, PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Graves, A.P, Boyce, S.E, Shoichet, B.K. | 登録日 | 2007-09-19 | 公開日 | 2008-04-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Rescoring docking hit lists for model cavity sites: predictions and experimental testing. J.Mol.Biol., 377, 2008
|
|
4F1S
| Crystal structure of human PI3K-gamma in complex with a pyridyl-triazine-sulfonamide inhibitor | 分子名称: | N-(5-{[3-(4-amino-6-methyl-1,3,5-triazin-2-yl)-5-(tetrahydro-2H-pyran-4-yl)pyridin-2-yl]amino}-2-chloropyridin-3-yl)methanesulfonamide, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION | 著者 | Whittington, D.A, Tang, J, Yakowec, P. | 登録日 | 2012-05-07 | 公開日 | 2012-08-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Synthesis and structure-activity relationships of dual PI3K/mTOR inhibitors based on a 4-amino-6-methyl-1,3,5-triazine sulfonamide scaffold. Bioorg.Med.Chem.Lett., 22, 2012
|
|
4F2K
| Macrophage Migration Inhibitory Factor covalently complexed with phenethylisothiocyanate | 分子名称: | ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, N-(2-phenylethyl)thioformamide, ... | 著者 | Tyndall, J.D.A, Bernhagen, J, Hampton, M.B, Wilbanks, S.M, Rutledge, M.T. | 登録日 | 2012-05-08 | 公開日 | 2012-06-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Macrophage migration inhibitory factor covalently complexed with phenethyl isothiocyanate Acta Crystallogr.,Sect.F, 68, 2012
|
|
2RDE
| Crystal structure of VCA0042 complexed with c-di-GMP | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Uncharacterized protein VCA0042 | 著者 | Benach, J, Swaminathan, S.S, Tamayo, R, Seetharaman, J, Handelman, S, Forouhar, F, Neely, H, Camilli, A, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2007-09-22 | 公開日 | 2007-10-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | The structural basis of cyclic diguanylate signal transduction by PilZ domains. Embo J., 26, 2007
|
|
2IA1
| Crystal structure of protein BH3703 from Bacillus halodurans, Pfam DUF600 | 分子名称: | BH3703 protein, GLYCEROL, SULFATE ION | 著者 | Ramagopal, U.A, Russell, M, Toro, R, Freeman, J.C, Reyes, C, Gheyi, T, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2006-09-06 | 公開日 | 2006-10-03 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Structure of hypothetical protein BH3703 from Bacillus halodurans To be Published
|
|
4F3M
| Crystal structure of CRISPR-associated protein | 分子名称: | 1,2-ETHANEDIOL, BH0337 protein, SULFATE ION | 著者 | Ke, A, Nam, K.H. | 登録日 | 2012-05-09 | 公開日 | 2012-08-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Cas5d Protein Processes Pre-crRNA and Assembles into a Cascade-like Interference Complex in Subtype I-C/Dvulg CRISPR-Cas System. Structure, 20, 2012
|
|
3OTC
| |
4EZ5
| CDK6 (monomeric) in complex with inhibitor | 分子名称: | Cyclin-dependent kinase 6, {5-[4-(dimethylamino)piperidin-1-yl]-1H-imidazo[4,5-b]pyridin-2-yl}[2-(isoquinolin-4-yl)pyridin-4-yl]methanone | 著者 | Chopra, R, Xu, M. | 登録日 | 2012-05-02 | 公開日 | 2013-02-06 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Fragment-Based Discovery of 7-Azabenzimidazoles as Potent, Highly Selective, and Orally Active CDK4/6 Inhibitors. ACS Med Chem Lett, 3, 2012
|
|
2RJZ
| Crystal structure of the type 4 fimbrial biogenesis protein PilO from Pseudomonas aeruginosa | 分子名称: | PilO protein, SULFATE ION | 著者 | Bonanno, J.B, Freeman, J, Bain, K.T, Chang, S, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2007-10-16 | 公開日 | 2007-11-06 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Periplasmic domains of Pseudomonas aeruginosa PilN and PilO form a stable heterodimeric complex. J.Mol.Biol., 394, 2009
|
|
2I5K
| Crystal structure of Ugp1p | 分子名称: | UTP--glucose-1-phosphate uridylyltransferase | 著者 | Roeben, A, Plitzko, J.M, Koerner, R, Boettcher, U.M.K, Siegers, K, Hayer-Hartl, M, Bracher, A. | 登録日 | 2006-08-25 | 公開日 | 2006-11-28 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural Basis for Subunit Assembly in UDP-glucose Pyrophosphorylase from Saccharomyces cerevisiae J.Mol.Biol., 364, 2006
|
|
3OW6
| Crystal Structure of HSP90 with N-Aryl-benzimidazolone I | 分子名称: | 1-(2,4-dihydroxyphenyl)-1,3-dihydro-2H-benzimidazol-2-one, Heat shock protein HSP 90-alpha | 著者 | Park, C.H. | 登録日 | 2010-09-17 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | N-aryl-benzimidazolones as novel small molecule HSP90 inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
|
|
4F8R
| |
3OWF
| Crystal structure of Staphylococcal nuclease variant Delta+PHS V66R at cryogenic temperature | 分子名称: | CALCIUM ION, PHOSPHATE ION, THYMIDINE-3',5'-DIPHOSPHATE, ... | 著者 | Schlessman, J.L, Khangulov, V, Heroux, A, Garcia-Moreno E, B. | 登録日 | 2010-09-17 | 公開日 | 2010-10-20 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Domain swapping promoted by a single mutation that introduces an ionizable group into the hydrophobic core of a protein To be Published
|
|
3P1C
| Crystal structure of the bromodomain of human CREBBP in complex with acetylated lysine | 分子名称: | CREB-binding protein, N(6)-ACETYLLYSINE, POTASSIUM ION, ... | 著者 | Filippakopoulos, P, Picaud, S, Feletar, I, Fedorov, O, Muniz, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2010-09-30 | 公開日 | 2010-11-24 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
|
|
2I7Q
| Crystal structure of Human Choline Kinase A | 分子名称: | CHLORIDE ION, Choline kinase alpha, UNKNOWN ATOM OR ION | 著者 | Rabeh, W.M, Tempel, W, Nedyalkova, L, Wasney, G, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2006-08-31 | 公開日 | 2006-09-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of Human Choline Kinase A To be Published
|
|
2R5F
| Putative sugar-binding domain of transcriptional regulator DeoR from Pseudomonas syringae pv. tomato | 分子名称: | SULFATE ION, Transcriptional regulator, putative | 著者 | Cuff, M.E, Duggan, E, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2007-09-03 | 公開日 | 2007-09-18 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Putative sugar-binding domain of trancsriptional regulator DeoR from Pseudomonas syringae pv. tomato. TO BE PUBLISHED
|
|
2I99
| Crystal structure of human Mu_crystallin at 2.6 Angstrom | 分子名称: | Mu-crystallin homolog, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Cheng, Z, Sun, L, He, J, Gong, W. | 登録日 | 2006-09-05 | 公開日 | 2007-02-27 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of human {micro}-crystallin complexed with NADPH Protein Sci., 16, 2007
|
|
3P0F
| Structure of hUPP2 in an inactive conformation with bound 5-benzylacyclouridine | 分子名称: | 1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE, COBALT (II) ION, MAGNESIUM ION, ... | 著者 | Roosild, T.P, Castronovo, S, Villoso, A. | 登録日 | 2010-09-28 | 公開日 | 2011-09-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | A novel structural mechanism for redox regulation of uridine phosphorylase 2 activity. J.Struct.Biol., 176, 2011
|
|
3P1U
| |
3P6C
| |
3P6K
| |
4EZD
| Crystal Structure of the UT-B Urea Transporter from Bos Taurus Bound to Selenourea | 分子名称: | OCTANOIC ACID (2-HYDROXY-1-HYDROXYMETHYL-HEPTADEC-3-ENYL)-AMIDE, Urea transporter 1, beta-D-glucopyranose, ... | 著者 | Cao, Y, Levin, E.J, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS) | 登録日 | 2012-05-02 | 公開日 | 2012-06-27 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure and permeation mechanism of a mammalian urea transporter. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
2I2O
| Crystal Structure of an eIF4G-like Protein from Danio rerio | 分子名称: | NICKEL (II) ION, eIF4G-like protein | 著者 | Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Mccoy, J.G, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2006-08-16 | 公開日 | 2006-08-29 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Crystal structure of an eIF4G-like protein from Danio rerio. Proteins, 78, 2010
|
|
2I3P
| K28R mutant of Homing Endonuclease I-CreI | 分子名称: | 5'-D(*CP*GP*AP*AP*AP*TP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*AP*TP*TP*TP*GP*C)-3', 5'-D(*GP*CP*AP*AP*AP*TP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*AP*TP*TP*TP*CP*G)-3', CALCIUM ION, ... | 著者 | Sussman, D, Rosen, L. | 登録日 | 2006-08-20 | 公開日 | 2006-09-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Homing endonuclease I-CreI derivatives with novel DNA target specificities. Nucleic Acids Res., 34, 2006
|
|
3P7P
| |