PDB: 10970 件ウェブページステータス検索Chemie searchBIRD

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4QYA	Crystal structure of human transthyretin variant V30M in complex with luteolin 分子名称: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, SODIUM ION, Transthyretin 著者 Begum, A, Olofsson, A, Sauer-Eriksson, A.E. 登録日 2014-07-24 公開日 2015-06-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The flavonoid luteolin, but not luteolin-7-o-glucoside, prevents a transthyretin mediated toxic response. Plos One, 10, 2015
4JFF	Preservation of peptide specificity during TCR-MHC contact dominated affinity enhancement of a melanoma-specific TCR 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... 著者 Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K. 登録日 2013-02-28 公開日 2013-05-29 最終更新日 2014-04-02 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 T-cell receptor specificity maintained by altered thermodynamics. J.Biol.Chem., 288, 2013
4R3Z	Crystal structure of human ArgRS-GlnRS-AIMP1 complex 分子名称: Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Arginine--tRNA ligase, cytoplasmic, ... 著者 Fu, Y, Kim, Y, Cho, Y. 登録日 2014-08-18 公開日 2014-10-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (4.033 Å) 主引用文献 Structure of the ArgRS-GlnRS-AIMP1 complex and its implications for mammalian translation Proc.Natl.Acad.Sci.USA, 111, 2014
4NN5	Cytokine receptor complex - Crystal form 1A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Cytokine receptor-like factor 2, ... 著者 Verstraete, K, van Schie, L, Savvides, S.N. 登録日 2013-11-16 公開日 2014-03-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.898 Å) 主引用文献 Structural basis of the proinflammatory signaling complex mediated by TSLP. Nat.Struct.Mol.Biol., 21, 2014
4QX7	Crystal structure of histone demethylase kdm2a-h3k36me2 with alpha-kg 分子名称: 2-OXOGLUTARIC ACID, Histone H3.2, Lysine-specific demethylase 2A, ... 著者 Cheng, Z.J, Patel, D.J. 登録日 2014-07-18 公開日 2014-11-05 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36. Genes Dev., 28, 2014
6TT3	Crystal structure of 'Res_S2 mutant human Angiotensin-1 converting enzyme N-domain in complex with SG6. 分子名称: (2~{S})-1-[(2~{S})-2-[[(1~{S})-1-[(2~{S})-1-[(2~{S})-2-azanyl-4-oxidanyl-4-oxidanylidene-butanoyl]pyrrolidin-2-yl]-2-oxidanyl-2-oxidanylidene-ethyl]amino]propanoyl]pyrrolidine-2-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Cozier, G.E, Acharya, K.R. 登録日 2019-12-23 公開日 2020-04-01 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 ACE-domain selectivity extends beyond direct interacting residues at the active site. Biochem.J., 477, 2020
4NKB	Crystal Structure of the cryptic polo box (CPB)of ZYG-1 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, ... 著者 Shimanovskaya, E, Dong, G. 登録日 2013-11-12 公開日 2014-08-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of the C. elegans ZYG-1 Cryptic Polo Box Suggests a Conserved Mechanism for Centriolar Docking of Plk4 Kinases. Structure, 22, 2014
4R5L	Crystal structure of the DnaK C-terminus (Dnak-SBD-C) 分子名称: CALCIUM ION, Chaperone protein DnaK, PHOSPHATE ION, ... 著者 Leu, J.I, Zhang, P, Murphy, M.E, Marmorstein, R, George, D.L. 登録日 2014-08-21 公開日 2014-09-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9701 Å) 主引用文献 Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket. Acs Chem.Biol., 9, 2014
6HKA	The solution structure of the micelle-associated FATC domain of the human protein kinase ataxia telangiectasia mutated (ATM) 分子名称: Immunoglobulin G-binding protein G,Serine-protein kinase ATM 著者 Abd Rahim, M.S, Dames, S.A. 登録日 2018-09-06 公開日 2019-03-27 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR- and MD simulation-based structural characterization of the membrane-associating FATC domain of ataxia telangiectasia mutated. J.Biol.Chem., 294, 2019
4JNJ	Structure based engineering of streptavidin monomer with a reduced biotin dissociation rate 分子名称: BIOTIN, Streptavidin/Rhizavidin Hybrid, ZINC ION 著者 DeMonte, D, Drake, E.J, Hong Lim, K, Gulick, A.M, Park, S. 登録日 2013-03-15 公開日 2013-05-29 最終更新日 2013-11-13 実験手法 X-RAY DIFFRACTION (1.902 Å) 主引用文献 Structure-based engineering of streptavidin monomer with a reduced biotin dissociation rate. Proteins, 81, 2013
4JNY	Crystal structure of PutA86-630 mutant D370A complexed with L-Tetrahydro-2-furoic acid 分子名称: Bifunctional protein PutA, FLAVIN-ADENINE DINUCLEOTIDE, PENTAETHYLENE GLYCOL, ... 著者 Tanner, J.J. 登録日 2013-03-16 公開日 2013-08-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Involvement of the beta 3-alpha 3 Loop of the Proline Dehydrogenase Domain in Allosteric Regulation of Membrane Association of Proline Utilization A. Biochemistry, 52, 2013
4RAU	crystal structure of RTOFab in complex with human PF4 分子名称: Platelet factor 4, RTOFab heavy chain, RTOFab light chain 著者 Cai, Z, Zhu, Z, Liu, Q, Greene, M.I. 登録日 2014-09-11 公開日 2016-03-16 実験手法 X-RAY DIFFRACTION (3.74 Å) 主引用文献 crystal structure of RTOFab in complex with platelet factor 4 To be Published
4JPO	5A resolution structure of Proteasome Assembly Chaperone Hsm3 in complex with a C-terminal fragment of Rpt1 分子名称: 26S protease regulatory subunit 7 homolog, DNA mismatch repair protein HSM3 著者 Lovell, S, Battaile, K.P, Singh, R, Roelofs, J. 登録日 2013-03-19 公開日 2013-04-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (5 Å) 主引用文献 Reconfiguration of the proteasome during chaperone-mediated assembly. Nature, 497, 2013
6TRO	Crystal structure of the T-cell receptor GVY01 bound to HLA A2*01-GVYDGREHTV 分子名称: Beta-2-microglobulin, MAGE-A4 peptide (amino acids 230-239), MHC class I antigen, ... 著者 Coles, C.H, McMurran, C, Lloyd, A, Hibbert, L, Lupardus, P.J, Cole, D.K, Harper, S. 登録日 2019-12-19 公開日 2020-06-24 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4. J.Biol.Chem., 295, 2020
6HRR	Structure of the TRPML2 ELD at pH 6.5 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, GLYCEROL, ... 著者 Bader, N, Viet, K.K, Wagner, A, Hellmich, U.A. 登録日 2018-09-28 公開日 2019-06-19 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of the Human TRPML2 Ion Channel Extracytosolic/Lumenal Domain. Structure, 27, 2019
4JM0	Structure of Human Cytomegalovirus Immune Modulator UL141 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein UL141 著者 Nemcovicova, I, Zajonc, D.M. 登録日 2013-03-13 公開日 2014-02-26 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 The structure of cytomegalovirus immune modulator UL141 highlights structural Ig-fold versatility for receptor binding. Acta Crystallogr.,Sect.D, 70, 2014
6TT1	Crystal structure of 'Res_S2 mutant human Angiotensin-1 converting enzyme N-domain in complex with 33RE. 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Cozier, G.E, Acharya, K.R. 登録日 2019-12-23 公開日 2020-04-01 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 ACE-domain selectivity extends beyond direct interacting residues at the active site. Biochem.J., 477, 2020
4JF3	Crystal structure of the mpmv tm retroviral fusion core 分子名称: CHLORIDE ION, Envelope glycoprotein 著者 Cook, J.D, Aydin, H, Lee, J.E. 登録日 2013-02-27 公開日 2013-10-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structures of Beta- and gammaretrovirus fusion proteins reveal a role for electrostatic stapling in viral entry. J.Virol., 88, 2014
4NJP	Proteolysis inside the membrane is a rate-governed reaction not Driven by substrate affinity 分子名称: Rhomboid protease GlpG 著者 Dickey, S.W, Baker, R.P, Cho, S, Urban, S. 登録日 2013-11-11 公開日 2013-12-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Proteolysis inside the Membrane Is a Rate-Governed Reaction Not Driven by Substrate Affinity. Cell(Cambridge,Mass.), 155, 2013
6TRN	Crystal structure of HLA A2*01-AVYDGREHTV 分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, MAGE-A4 peptide (amino acids 230-239) variant, ... 著者 Coles, C.H, McMurran, C, Lloyd, A, Hibbert, L, Lupardus, P.J, Cole, D.K, Harper, S. 登録日 2019-12-19 公開日 2020-06-24 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4. J.Biol.Chem., 295, 2020
6TT4	Crystal structure of 'Res_S2 mutant human Angiotensin-1 converting enzyme N-domain in complex with omapatrilat. 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Cozier, G.E, Acharya, K.R. 登録日 2019-12-23 公開日 2020-04-01 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 ACE-domain selectivity extends beyond direct interacting residues at the active site. Biochem.J., 477, 2020
6I09	Crystal structure of RlpA SPOR domain from Pseudomonas aeruginosa in complex with denuded glycan obtained by soaking 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-beta-muramic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-methyl 2-acetamido-3-O-[(1R)-1-carboxyethyl]-2-deoxy-beta-D-glucopyranoside, Endolytic peptidoglycan transglycosylase RlpA 著者 Alcorlo, M, Hermoso, J.A. 登録日 2018-10-25 公開日 2019-11-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Structural basis of denuded glycan recognition by SPOR domains in bacterial cell division. Nat Commun, 10, 2019
4MFJ	The crystal structure of acyltransferase 分子名称: Putative uncharacterized protein tcp24 著者 Lyu, S.Y, Liu, Y.C, Chang, C.Y, Huang, C.J, Li, T.L. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus J.Am.Chem.Soc., 136, 2014
4MFL	The crystal structure of acyltransferase in complex with decanoyl-CoA and Tei pseudoaglycone 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose, Putative uncharacterized protein tcp24, ... 著者 Lyu, S.Y, Liu, Y.C, Chang, C.Y, Huang, C.J, Li, T.L. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus J.Am.Chem.Soc., 136, 2014
6I0A	Crystal structure of RlpA SPOR domain from Pseudomonas aeruginosa in complex with nuded glycan obtained by co-crystallization 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-beta-muramic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-methyl 2-acetamido-3-O-[(1R)-1-carboxyethyl]-2-deoxy-beta-D-glucopyranoside, Endolytic peptidoglycan transglycosylase RlpA 著者 Alcorlo, M, Hermoso, J.A. 登録日 2018-10-25 公開日 2019-11-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structural basis of denuded glycan recognition by SPOR domains in bacterial cell division. Nat Commun, 10, 2019

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