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5EMK
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BU of 5emk by Molmil
Crystal structure of PRMT5:MEP50 with Compound 9 and sinefungin
分子名称: GLYCEROL, Methylosome protein 50, Protein arginine N-methyltransferase 5, ...
著者Boriack-Sjodin, P.A, Jin, L.
登録日2015-11-06
公開日2016-02-24
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666.
ACS Med Chem Lett, 7, 2016
6C9S
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BU of 6c9s by Molmil
Mycobacterium tuberculosis adenosine kinase bound to (2R,3R,4S,5R)-2-(6-([1,1'-biphenyl]-4-ylethynyl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
分子名称: 6-[([1,1'-biphenyl]-4-yl)ethynyl]-9-beta-D-ribofuranosyl-9H-purine, Adenosine kinase, SODIUM ION, ...
著者Crespo, R.A, TB Structural Genomics Consortium (TBSGC)
登録日2018-01-28
公開日2019-05-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase.
J.Med.Chem., 62, 2019
6C9Q
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BU of 6c9q by Molmil
Mycobacterium tuberculosis adenosine kinase bound to 5'-aminoadenosine
分子名称: 5'-amino-5'-deoxyadenosine, Adenosine kinase
著者Crespo, R.A, TB Structural Genomics Consortium (TBSGC)
登録日2018-01-28
公開日2019-05-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase.
J.Med.Chem., 62, 2019
5EMB
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BU of 5emb by Molmil
Crystal structure of the SNX27 PDZ domain bound to the C-terminal phosphorylated PTHR PDZ binding motif
分子名称: GLU-GLU-TRP-SEP-THR-VAL-MET, Sorting nexin-27
著者Collins, B.M, Clairfeuille, T.
登録日2015-11-06
公開日2016-09-07
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (0.85 Å)
主引用文献A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex.
Nat.Struct.Mol.Biol., 23, 2016
5EML
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BU of 5eml by Molmil
Crystal structure of PRMT5:MEP50 with Compound 10 and SAM
分子名称: GLYCEROL, Methylosome protein 50, Protein arginine N-methyltransferase 5, ...
著者Boriack-Sjodin, P.A, Jin, L.
登録日2015-11-06
公開日2016-02-24
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666.
ACS Med Chem Lett, 7, 2016
5EMJ
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BU of 5emj by Molmil
Crystal structure of PRMT5:MEP50 with Compound 8 and sinefungin
分子名称: (2~{S})-1-(3,4-dihydro-1~{H}-isoquinolin-2-yl)-3-[[4-(3-methylbenzimidazol-5-yl)pyridin-2-yl]amino]propan-2-ol, GLYCEROL, Methylosome protein 50, ...
著者Boriack-Sjodin, P.A, Jin, L.
登録日2015-11-06
公開日2016-02-24
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.273 Å)
主引用文献Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666.
ACS Med Chem Lett, 7, 2016
5EO1
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BU of 5eo1 by Molmil
Crystal Structure of HLA-B0702-RL9
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ...
著者Josephs, T.M, Gras, S, Rossjohn, J.
登録日2015-11-10
公開日2016-02-24
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection.
J Immunol., 196, 2016
6C9V
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BU of 6c9v by Molmil
Mycobacterium tuberculosis adenosine kinase bound to (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(4-phenylpiperazin-1-yl)-9H-purin-9-yl)tetrahydrofuran-3,4-diol
分子名称: (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(4-phenylpiperazin-1-yl)-9H-purin-9-yl]tetrahydrofuran-3,4-diol, Adenosine kinase, GLYCEROL, ...
著者Crespo, R.A, TB Structural Genomics Consortium (TBSGC)
登録日2018-01-28
公開日2019-05-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase.
J.Med.Chem., 62, 2019
5ENW
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BU of 5enw by Molmil
Structure of HLA-A2:01 with peptide G9L
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Remesh, S.G, Zajonc, D.M.
登録日2015-11-09
公開日2016-11-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT.
J. Biol. Chem., 292, 2017
5EO0
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BU of 5eo0 by Molmil
Crystal Structure of HLA-B0702-RFL9
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ...
著者Josephs, T.M, Gras, S, Rossjohn, J.
登録日2015-11-10
公開日2016-02-24
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection.
J Immunol., 196, 2016
4DR6
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BU of 4dr6 by Molmil
Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with codon, near-cognate transfer RNA anticodon stem-loop mismatched at the first codon position and streptomycin bound
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G.
登録日2012-02-16
公開日2012-11-14
最終更新日2025-02-19
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A structural basis for streptomycin-induced misreading of the genetic code.
Nat Commun, 4, 2013
5EL2
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BU of 5el2 by Molmil
Crystal structure of Odorant Binding Protein 1 from Anopheles gambiae (AgamOBP1) with Icaridin (butan-2-yl 2-(2-hydroxyethyl)piperidine-1-carboxylate)
分子名称: AGAP003309-PA, Icaridin, MAGNESIUM ION
著者Drakou, C.E, Tsitsanou, K.E, Zographos, S.E.
登録日2015-11-04
公開日2016-08-31
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The crystal structure of the AgamOBP1Icaridin complex reveals alternative binding modes and stereo-selective repellent recognition.
Cell. Mol. Life Sci., 74, 2017
5ET6
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BU of 5et6 by Molmil
Human muscle fructose-1,6-bisphosphatase in inactive T-state in complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase isozyme 2
著者Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D.
登録日2015-11-17
公開日2016-04-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.845 Å)
主引用文献T-to-R switch of muscle fructose-1,6-bisphosphatase involves fundamental changes of secondary and quaternary structure.
Acta Crystallogr D Struct Biol, 72, 2016
4ID5
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BU of 4id5 by Molmil
HIV-1 reverse transcriptase with bound fragment at the RNase H primer grip site
分子名称: 1-methyl-5-phenyl-1H-pyrazole-4-carboxylic acid, 4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, DIMETHYL SULFOXIDE, ...
著者Bauman, J.D, Patel, D, Arnold, E.
登録日2012-12-11
公開日2013-02-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Detecting Allosteric Sites of HIV-1 Reverse Transcriptase by X-ray Crystallographic Fragment Screening.
J.Med.Chem., 56, 2013
5ET7
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BU of 5et7 by Molmil
Human muscle fructose-1,6-bisphosphatase in inactive T-state
分子名称: Fructose-1,6-bisphosphatase isozyme 2
著者Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D.
登録日2015-11-17
公開日2016-04-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.989 Å)
主引用文献T-to-R switch of muscle fructose-1,6-bisphosphatase involves fundamental changes of secondary and quaternary structure.
Acta Crystallogr D Struct Biol, 72, 2016
5EUB
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BU of 5eub by Molmil
Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with 2-amino-MTA and sulfate
分子名称: (2~{R},3~{R},4~{S},5~{S})-2-[2,6-bis(azanyl)purin-9-yl]-5-(methylsulfanylmethyl)oxolane-3,4-diol, CHLORIDE ION, GLYCEROL, ...
著者Cameron, S.A, Firestone, R.S, Schramm, V.L, Almo, S.C.
登録日2015-11-18
公開日2016-12-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with 2-amino-MTA and sulfate
To be published
5EU5
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BU of 5eu5 by Molmil
HLA Class I antigen
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K.
登録日2015-11-18
公開日2016-03-02
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
5EU6
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BU of 5eu6 by Molmil
HLA Class I antigen
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K.
登録日2015-11-18
公開日2016-03-02
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
5EU4
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BU of 5eu4 by Molmil
HLA Class I antigen
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K.
登録日2015-11-18
公開日2016-03-02
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
4N0A
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BU of 4n0a by Molmil
Crystal structure of Lsm2-3-Pat1C complex from Saccharomyces cerevisiae
分子名称: DNA topoisomerase 2-associated protein PAT1, U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3
著者Wu, D.H.
登録日2013-10-01
公開日2013-12-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Lsm2 and Lsm3 bridge the interaction of the Lsm1-7 complex with Pat1 for decapping activation
Cell Res., 24, 2014
5EU3
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BU of 5eu3 by Molmil
HLA Class I antigen
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K.
登録日2015-11-18
公開日2016-03-02
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
5EUO
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BU of 5euo by Molmil
PF6-M1-HLA-A2
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Yang, X.
登録日2015-11-18
公開日2016-11-23
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of PF6-M1-HLA-A2 complex
To Be Published
4DR4
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BU of 4dr4 by Molmil
Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with codon, cognate transfer RNA anticodon stem-loop and multiple copies of paromomycin molecules bound
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G.
登録日2012-02-16
公開日2012-11-14
最終更新日2025-02-19
実験手法X-RAY DIFFRACTION (3.969 Å)
主引用文献A structural basis for streptomycin-induced misreading of the genetic code.
Nat Commun, 4, 2013
5EYT
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BU of 5eyt by Molmil
Crystal Structure of Adenylosuccinate Lyase from Schistosoma mansoni in complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, Adenylosuccinate lyase
著者Romanello, L, Torini, J.R, Bird, L, Nettleship, J, Owens, R, Reddivari, Y, Brandao-Neto, J, Pereira, H.M.
登録日2015-11-25
公開日2016-11-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3649 Å)
主引用文献Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL).
Mol. Biochem. Parasitol., 214, 2017
6Y5V
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Structure of Human Potassium Chloride Transporter KCC3b (S45D/T940D/T997D) in KCl
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 12 member 6, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Chi, G, Man, H, Ebenhoch, R, Reggiano, G, Pike, A.C.W, Wang, D, McKinley, G, Mukhopadhyay, S.M.M, MacLean, E.M, Chalk, R, Moreau, C, Snee, M, Bohstedt, T, Singh, N.K, Abrusci, P, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Marsden, B.D, Burgess-Brown, N.A, DiMaio, F, Duerr, K.L.
登録日2020-02-25
公開日2020-07-15
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (4.08 Å)
主引用文献Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters.
Embo J., 40, 2021

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件を2025-07-09に公開中

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