8Q4I
 
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6UXO
 | | Crystal structure of BAK core domain BH3-groove-dimer in complex with DDM | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Bcl-2 homologous antagonist/killer, ... | | 著者 | Cowan, A.D, Colman, P.M, Czabotar, P.E. | | 登録日 | 2019-11-07 | | 公開日 | 2020-09-02 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.799 Å) | | 主引用文献 | BAK core dimers bind lipids and can be bridged by them.
Nat.Struct.Mol.Biol., 27, 2020
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6UO8
 | | Human metabotropic GABA(B) receptor bound to agonist SKF97541 and positive allosteric modulator GS39783 | | 分子名称: | (R)-(3-aminopropyl)methylphosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Shaye, H, Han, G.W, Gati, C, Cherezov, V. | | 登録日 | 2019-10-14 | | 公開日 | 2020-06-10 | | 最終更新日 | 2020-08-26 | | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | | 主引用文献 | Structural basis of the activation of a metabotropic GABA receptor.
Nature, 584, 2020
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1C4T
 | | CATALYTIC DOMAIN FROM TRIMERIC DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE | | 分子名称: | PROTEIN (DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE), SULFATE ION | | 著者 | Knapp, J.E, Carroll, D, Lawson, J.E, Ernst, S.R, Reed, L.J, Hackert, M.L. | | 登録日 | 1999-09-22 | | 公開日 | 2000-02-18 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Expression, purification, and structural analysis of the trimeric form of the catalytic domain of the Escherichia coli dihydrolipoamide succinyltransferase.
Protein Sci., 9, 2000
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6VW1
 | | Structure of SARS-CoV-2 chimeric receptor-binding domain complexed with its receptor human ACE2 | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Shang, J, Ye, G, Shi, K, Wan, Y.S, Aihara, H, Li, F. | | 登録日 | 2020-02-18 | | 公開日 | 2020-03-04 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Structural basis of receptor recognition by SARS-CoV-2.
Nature, 581, 2020
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1N3J
 | | Structure and Substrate of a Histone H3 Lysine Methyltransferase from Paramecium Bursaria Chlorella Virus 1 | | 分子名称: | Histone H3 Lysine Methyltransferase | | 著者 | Manzur, K.L, Farooq, A, Zeng, L, Plotnikova, O, Sachchidanand, Koch, A.W, Zhou, M.-M. | | 登録日 | 2002-10-28 | | 公開日 | 2003-01-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A dimeric viral SET domain methyltransferase specific to Lys27 of histone H3.
Nat.Struct.Biol., 10, 2003
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8QOI
 | | Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNA | | 分子名称: | 18S rRNA (1740-MER), 28S rRNA (3773-MER), 40S ribosomal protein S10, ... | | 著者 | Holvec, S, Barchet, C, Frechin, L, Hazemann, I, von Loeffelholz, O, Klaholz, B.P. | | 登録日 | 2023-09-29 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (1.9 Å) | | 主引用文献 | The structure of the human 80S ribosome at 1.9 angstrom resolution reveals the molecular role of chemical modifications and ions in RNA.
Nat.Struct.Mol.Biol., 2024
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6TA7
 | | CRYSTAL STRUCTURE OF HUMAN G3BP1-NTF2 IN COMPLEX WITH HUMAN CAPRIN1-DERIVED SOLOMON MOTIF | | 分子名称: | CHLORIDE ION, Caprin-1, Ras GTPase-activating protein-binding protein 1, ... | | 著者 | Schulte, T, Achour, A, Panas, M.D, McInerney, G.M. | | 登録日 | 2019-10-29 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Caprin-1 binding to the critical stress granule protein G3BP1 is regulated by pH
Biorxiv, 2021
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1AD0
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3S8G
 | | 1.8 A structure of ba3 cytochrome c oxidase mutant (A120F) from Thermus thermophilus in lipid environment | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, COPPER (II) ION, Cytochrome c oxidase polypeptide 2A, ... | | 著者 | Tiefenbrunn, T, Liu, W, Chen, Y, Katritch, V, Stout, C.D, Fee, J.A, Cherezov, V. | | 登録日 | 2011-05-27 | | 公開日 | 2011-08-03 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | High resolution structure of the ba3 cytochrome c oxidase from Thermus thermophilus in a lipidic environment.
Plos One, 6, 2011
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8OL9
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6TUL
 | | Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0021177 | | 分子名称: | D-MALATE, Fab C0021177 heavy chain (IgG1), Fab C0021177 light chain (IgG1), ... | | 著者 | Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M. | | 登録日 | 2020-01-07 | | 公開日 | 2020-06-10 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
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6HYX
 | | THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Y197F-P250C | | 分子名称: | CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Proton-gated ion channel, ... | | 著者 | Hu, H.D, Delarue, M. | | 登録日 | 2018-10-22 | | 公開日 | 2018-12-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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2WPT
 | | The crystal structure of Im2 in complex with colicin E9 DNase | | 分子名称: | COLICIN-E2 IMMUNITY PROTEIN, COLICIN-E9, GLYCEROL, ... | | 著者 | Meenan, N.A, Sharma, A, Fleishman, S.J, Macdonald, C.J, Boetzel, R, Moore, G.R, Baker, D, Kleanthous, C. | | 登録日 | 2009-08-10 | | 公開日 | 2010-06-02 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | The Structural and Energetic Basis for High Selectivity in a High-Affinity Protein-Protein Interaction.
Proc.Natl.Acad.Sci.USA, 107, 2010
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3S8F
 | | 1.8 A structure of ba3 cytochrome c oxidase from Thermus thermophilus in lipid environment | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, COPPER (II) ION, Cytochrome c oxidase polypeptide 2A, ... | | 著者 | Tiefenbrunn, T, Liu, W, Chen, Y, Katritch, V, Stout, C.D, Fee, J.A, Cherezov, V. | | 登録日 | 2011-05-27 | | 公開日 | 2011-08-03 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | High resolution structure of the ba3 cytochrome c oxidase from Thermus thermophilus in a lipidic environment.
Plos One, 6, 2011
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8OID
 | | Cryo-EM structure of ADP-bound, filamentous beta-actin harboring the N111S mutation | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | 著者 | Oosterheert, W, Blanc, F.E.C, Roy, A, Belyy, A, Hofnagel, O, Hummer, G, Bieling, P, Raunser, S. | | 登録日 | 2023-03-22 | | 公開日 | 2023-08-09 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Molecular mechanisms of inorganic-phosphate release from the core and barbed end of actin filaments.
Nat.Struct.Mol.Biol., 30, 2023
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8Q1K
 | | Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ... | | 著者 | Roske, Y, Daumke, O, Damme, M. | | 登録日 | 2023-07-31 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation.
Nucleic Acids Res., 52, 2024
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1CCZ
 | | CRYSTAL STRUCTURE OF THE CD2-BINDING DOMAIN OF CD58 (LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3) AT 1.8-A RESOLUTION | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (CD58) | | 著者 | Ikemizu, S, Sparks, L.M, Van Der Merwe, P.A, Harlos, K, Stuart, D.I, Jones, E.Y, Davis, S.J. | | 登録日 | 1999-03-02 | | 公開日 | 1999-04-05 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of the CD2-binding domain of CD58 (lymphocyte function-associated antigen 3) at 1.8-A resolution.
Proc.Natl.Acad.Sci.USA, 96, 1999
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6HYA
 | | THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Q193L | | 分子名称: | CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Proton-gated ion channel | | 著者 | Hu, H.D, Delarue, M. | | 登録日 | 2018-10-19 | | 公開日 | 2018-12-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (3.39 Å) | | 主引用文献 | Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6HYZ
 | | THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT K248C | | 分子名称: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | | 著者 | Hu, H.D, Delarue, M. | | 登録日 | 2018-10-22 | | 公開日 | 2018-12-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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8Q1X
 | | Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ... | | 著者 | Roske, Y, Daumke, O, Damme, M. | | 登録日 | 2023-08-01 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation.
Nucleic Acids Res., 52, 2024
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5GTU
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5G1R
 | | Open conformation of Francisella tularensis ClpP at 1.9 A | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ... | | 著者 | Diaz-Saez, L, Hunter, W.N. | | 登録日 | 2016-03-29 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Open and compressed conformations of Francisella tularensis ClpP.
Proteins, 85, 2017
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4BM7
 | | Crystal Structure of IgG Fc F241A mutant with native glycosylation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, IG GAMMA-1 CHAIN C REGION | | 著者 | Yu, X, Baruah, K, Harvey, D.J, Vasiljevic, S, Alonzi, D.S, Song, B, Higgins, M.K, Bowden, T.A, Crispin, M, Scanlan, C.N. | | 登録日 | 2013-05-07 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Engineering Hydrophobic Protein-Carbohydrate Interactions to Fine-Tune Monoclonal Antibodies.
J.Am.Chem.Soc., 135, 2013
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7OJD
 | | SaFtsZ(D46A) complexed with GDP | | 分子名称: | 1,2-ETHANEDIOL, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M. | | 登録日 | 2021-05-14 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
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