PDB: 10970 件ウェブページステータス検索Chemie searchBIRD

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5CVN	WDR48 (2-580):USP46~ubiquitin ternary complex 分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, WD repeat-containing protein 48, ... 著者 Harris, S.F, Yin, J. 登録日 2015-07-27 公開日 2015-10-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.36 Å) 主引用文献 Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46. Structure, 23, 2015
6NK0	EphA2 LBD in complex with bA-WLA-Yam peptide 分子名称: 1,2-ETHANEDIOL, 6-AMINOHEXANOIC ACID, DI(HYDROXYETHYL)ETHER, ... 著者 Lechtenberg, B.C, Pasquale, E.B. 登録日 2019-01-04 公開日 2019-05-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling. J.Biol.Chem., 294, 2019
3K9Q	Crystal structure of C151G mutant of Glyceraldehyde 3-phosphate dehydrogenase 1 from Methicillin resistant Staphylococcus aureus (MRSA252) at 2.5 angstrom resolution 分子名称: CHLORIDE ION, GLYCEROL, Glyceraldehyde-3-phosphate dehydrogenase 1, ... 著者 Mukherjee, S, Dutta, D, Saha, B, Das, A.K. 登録日 2009-10-16 公開日 2010-08-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of glyceraldehyde-3-phosphate dehydrogenase 1 from methicillin-resistant Staphylococcus aureus MRSA252 provides novel insights into substrate binding and catalytic mechanism. J.Mol.Biol., 401, 2010
6NAG	X-ray structure of a secreted C11 cysteine protease from Bacteroides thetaiotaomicron "iotapain 分子名称: Clostripain-related protein, PROLINE 著者 Wolan, D.W, Gonzalez-Paez, G.E, Roncase, E.J. 登録日 2018-12-05 公開日 2019-12-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.683 Å) 主引用文献 X-ray Structures of Two Bacteroides thetaiotaomicron C11 Proteases in Complex with Peptide-Based Inhibitors. Biochemistry, 58, 2019
5MIO	KIF2C-DARPIN FUSION PROTEIN BOUND TO TUBULIN 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF2C,KIF2C FUSED TO A DARPIN,KIF2C FUSED TO A DARPIN, ... 著者 Wang, W, Gigant, B. 登録日 2016-11-28 公開日 2017-07-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 Insight into microtubule disassembly by kinesin-13s from the structure of Kif2C bound to tubulin. Nat Commun, 8, 2017
5DAH	Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide 分子名称: Histone H3 peptide, Protein AF-10, SULFATE ION, ... 著者 Chen, S, Patel, D.J. 登録日 2015-08-19 公開日 2015-10-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.611 Å) 主引用文献 The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79. Mol.Cell, 60, 2015
5D93	Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from a Mouse QSOX1-Specific Antibody 分子名称: Heavy Chain of Fab Fragment from a Mouse QSOX1-Specific Antibody, Light Chain of Fab Fragment from a Mouse QSOX1-Specific Antibody, Sulfhydryl oxidase 1 著者 Grossman, I, Fass, D. 登録日 2015-08-18 公開日 2016-02-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.201 Å) 主引用文献 Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma. Protein Eng.Des.Sel., 29, 2016
5NQW	IgE-Fc in complex with single domain antibody 026 分子名称: 026, GLYCEROL, Immunoglobulin heavy constant epsilon, ... 著者 Laursen, N.S, Jabs, F, Spillner, E, Andersen, G.R. 登録日 2017-04-21 公開日 2018-01-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts Fc epsilon RI interaction. Nat Commun, 9, 2018
6D38	Photodissociable dimeric Dronpa green fluorescent protein variant M (pdDronpaM) 分子名称: Fluorescent protein Dronpa, SULFATE ION 著者 Zhou, X, Fan, L, Lin, M. 登録日 2018-04-14 公開日 2018-05-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Optical control of cell signaling by single-chain photoswitchable kinases. Science, 355, 2017
7Y0D	Cryo-EM structure of the Mycobacterium smegmatis DNA integrity scanning protein (MsDisA). 分子名称: DNA integrity scanning protein DisA 著者 Gautam, S, Vinothkumar, K.R, Chatterji, D. 登録日 2022-06-04 公開日 2023-02-08 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Regulatory mechanisms of c-di-AMP synthase (MsDisA) protein from Mycobacterium smegmatis revealed by a structure - function analysis. Protein Sci., 32, 2023
5DE1	Crystal structure of human IDH1 in complex with GSK321A 分子名称: (7R)-1-(4-fluorobenzyl)-N-{3-[(1S)-1-hydroxyethyl]phenyl}-7-methyl-5-(1H-pyrrol-2-ylcarbonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxamide, Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Concha, N.O, Smallwood, A, Qi, H. 登録日 2015-08-25 公開日 2015-10-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 New IDH1 mutant inhibitors for treatment of acute myeloid leukemia. Nat.Chem.Biol., 11, 2015
5DEP	Structure of Pseudomonas aeruginosa LpxA in complex with UDP-GlcNAc 分子名称: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, PHOSPHATE ION, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE 著者 Smith, E.W, Chen, Y. 登録日 2015-08-25 公開日 2015-09-16 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Structures of Pseudomonas aeruginosa LpxA Reveal the Basis for Its Substrate Selectivity. Biochemistry, 54, 2015
3KRG	Structural insights into substrate specificity and the anti beta-elimination mechanism of pectate lyase 分子名称: COBALT (II) ION, GLYCEROL, Pectate lyase, ... 著者 Pickersgill, R.W, To, T.T. 登録日 2009-11-18 公開日 2010-02-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural insights into substrate specificity and the anti beta-elimination mechanism of pectate lyase Biochemistry, 49, 2010
6OJ1	Crystal Structure of Aspergillus fumigatus Ega3 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Bamford, N.C, Subramanian, A.S, Millan, C, Uson, I, Howell, P.L. 登録日 2019-04-10 公開日 2019-08-14 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Ega3 from the fungal pathogenAspergillus fumigatusis an endo-alpha-1,4-galactosaminidase that disrupts microbial biofilms. J.Biol.Chem., 294, 2019
5DAP	Fe(II)/(alpha)ketoglutarate-dependent dioxygenase AsqJ 分子名称: 2-OXOGLUTARIC ACID, NICKEL (II) ION, Phytanoyl-CoA dioxygenase family protein (AFU_orthologue AFUA_8G00230) 著者 Groll, M, Braeuer, A. 登録日 2015-08-20 公開日 2015-11-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure of the Dioxygenase AsqJ: Mechanistic Insights into a One-Pot Multistep Quinolone Antibiotic Biosynthesis. Angew.Chem.Int.Ed.Engl., 55, 2016
5DAW	Fe(II)/(alpha)ketoglutarate-dependent dioxygenase AsqJ in complex with cyclopeptin 分子名称: 2-OXOGLUTARIC ACID, NICKEL (II) ION, Phytanoyl-CoA dioxygenase family protein (AFU_orthologue AFUA_8G00230), ... 著者 Groll, M, Braeuer, A. 登録日 2015-08-20 公開日 2015-11-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of the Dioxygenase AsqJ: Mechanistic Insights into a One-Pot Multistep Quinolone Antibiotic Biosynthesis. Angew.Chem.Int.Ed.Engl., 55, 2016
5DAG	Crystal structure of PZP domain of human AF10 protein 分子名称: Protein AF-10, ZINC ION 著者 Chen, S, Patel, D.J. 登録日 2015-08-19 公開日 2015-10-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79. Mol.Cell, 60, 2015
5LRG	Crystal structure of the porcine carboxypeptidase B - Anabaenopeptin B complex 分子名称: Anabaenopeptin B, Carboxypeptidase B, ZINC ION 著者 Schreuder, H, Liesum, A, Loenze, P. 登録日 2016-08-19 公開日 2016-09-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Isolation, Co-Crystallization and Structure-Based Characterization of Anabaenopeptins as Highly Potent Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFIa). Sci Rep, 6, 2016
5LT8	Structure of the Epigenetic Oncogene MMSET and inhibition by N-Alkyl Sinefungin Derivatives 分子名称: Histone-lysine N-methyltransferase SETD2, SINEFUNGIN, ZINC ION 著者 Tisi, D, Pathuri, P, Heightman, T. 登録日 2016-09-06 公開日 2016-10-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin Derivatives. ACS Chem. Biol., 11, 2016
3KSD	Crystal Structure of C151S+H178N mutant of Glyceraldehyde-3-phosphate dehydrogenase 1 (GAPDH1) from Staphylococcus aureus MRSA252 complexed with NAD at 2.2 angstrom resolution 分子名称: Glyceraldehyde-3-phosphate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Mukherjee, S, Dutta, D, Saha, B, Das, A.K. 登録日 2009-11-22 公開日 2010-08-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of glyceraldehyde-3-phosphate dehydrogenase 1 from methicillin-resistant Staphylococcus aureus MRSA252 provides novel insights into substrate binding and catalytic mechanism. J.Mol.Biol., 401, 2010
3KV3	Crystal structure of C151S mutant of Glyceraldehyde-3-phosphate dehydrogenase 1 (GAPDH 1)from methicillin resistant Staphylococcus aureus MRSA252 complexed with NAD and G3P 分子名称: 3-PHOSPHOGLYCERIC ACID, GAPDH, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Mukherjee, S, Dutta, D, Saha, B, Das, A.K. 登録日 2009-11-29 公開日 2010-08-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of glyceraldehyde-3-phosphate dehydrogenase 1 from methicillin-resistant Staphylococcus aureus MRSA252 provides novel insights into substrate binding and catalytic mechanism. J.Mol.Biol., 401, 2010
5M55	Nek2 bound to arylaminopurine 71 分子名称: 6-[(~{Z})-2-(diethylamino)ethenyl]-~{N}-phenyl-7~{H}-purin-2-amine, CHLORIDE ION, SULFATE ION, ... 著者 Bayliss, R. 登録日 2016-10-20 公開日 2016-11-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-guided design of purine-based probes for selective Nek2 inhibition. Oncotarget, 8, 2017
5D79	Structure of BBE-like #28 from Arabidopsis thaliana 分子名称: Berberine bridge enzyme-like protein, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Daniel, B, Kumar, P, Gruber, K. 登録日 2015-08-13 公開日 2016-06-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.849 Å) 主引用文献 Structure of a Berberine Bridge Enzyme-Like Enzyme with an Active Site Specific to the Plant Family Brassicaceae. Plos One, 11, 2016
6BMX	Non-receptor Protein Tyrosine Phosphatase SHP2 in Complex with Allosteric Inhibitor SHP844 分子名称: 1-(3-chloro-4-{[1-(2-hydroxy-3-methoxyphenyl)-5-oxo[1,2,4]triazolo[4,3-a]quinazolin-4(5H)-yl]methyl}benzene-1-carbonyl)-L-proline, GLYCEROL, PHOSPHATE ION, ... 著者 Stams, T, Fodor, M. 登録日 2017-11-15 公開日 2018-01-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.424 Å) 主引用文献 Dual Allosteric Inhibition of SHP2 Phosphatase. ACS Chem. Biol., 13, 2018
3L1O	Crystal structure of monoclonal antibody MN423 Fab fragment with free combining site, crystallized in the presence of zinc 分子名称: IMIDAZOLE, MONOCLONAL ANTIBODY FAB FRAGMENT MN423 H CHAIN, MONOCLONAL ANTIBODY FAB FRAGMENT MN423 L CHAIN, ... 著者 Skrabana, R, Sevcik, J. 登録日 2009-12-14 公開日 2010-03-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Monoclonal antibody MN423 as a stable mold facilitates structure determination of disordered tau protein J.Struct.Biol., 171, 2010

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