PDB: 1697 件ウェブページステータス検索Chemie searchBIRD

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6RT0	cryo-em structure of alpha-synuclein fibril polymorph 2A 分子名称: Alpha-synuclein 著者 Guerrero-Ferreira, R, Taylor, N.M.I, Arteni, A.A, Melki, R, Meier, B.H, Bockmann, A, Bousset, L, Stahlberg, H. 登録日 2019-05-22 公開日 2019-06-26 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy. Elife, 8, 2019
7VPR	Crystal structure of the ligand-binding domain of C. glabrata Upc2 in complex with ergosterol 分子名称: ERGOSTEROL, Sterol uptake control protein 2 (Upc2) 著者 Tan, L, Im, Y.J. 登録日 2021-10-17 公開日 2022-09-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Structural basis for activation of fungal sterol receptor Upc2 and azole resistance. Nat.Chem.Biol., 18, 2022
6SST	cryo-em structure of alpha-synuclein fibril polymorph 2B 分子名称: Alpha-synuclein 著者 Guerrero-Ferreira, R, Taylor, N.M.I, Arteni, A.A, Melki, R, Meier, B.H, Bockmann, A, Bousset, L, Stahlberg, H. 登録日 2019-09-09 公開日 2019-12-18 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy. Elife, 8, 2019
6SSX	cryo-em structure of alpha-synuclein fibril polymorph 2A 分子名称: Alpha-synuclein 著者 Guerrero-Ferreira, R, Taylor, N.M.I, Arteni, A.A, Melki, R, Meier, B.H, Bockmann, A, Bousset, L, Stahlberg, H. 登録日 2019-09-09 公開日 2019-12-18 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.98 Å) 主引用文献 Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy. Elife, 8, 2019
1XKA	FACTOR XA COMPLEXED WITH A SYNTHETIC INHIBITOR FX-2212A,(2S)-(3'-AMIDINO-3-BIPHENYLYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID 分子名称: (2S)-(3'-AMIDINO-3-BIPHENYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID, BLOOD COAGULATION FACTOR XA, CALCIUM ION 著者 Kamata, K, Kim, S.H. 登録日 1998-03-19 公開日 1999-03-23 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for chemical inhibition of human blood coagulation factor Xa. Proc.Natl.Acad.Sci.USA, 95, 1998
1XKB	FACTOR XA COMPLEXED WITH A SYNTHETIC INHIBITOR FX-2212A,(2S)-(3'-AMIDINO-3-BIPHENYLYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID 分子名称: (2S)-(3'-AMIDINO-3-BIPHENYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID, BLOOD COAGULATION FACTOR XA, CALCIUM ION 著者 Kamata, K, Kim, S.H. 登録日 1998-03-19 公開日 1999-03-23 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for chemical inhibition of human blood coagulation factor Xa. Proc.Natl.Acad.Sci.USA, 95, 1998
6CIL	PRE-REACTION COMPLEX, RAG1(E962Q)/2-INTACT/INTACT 12/23RSS COMPLEX IN MN2+ 分子名称: High mobility group protein B1, Intact 12RSS substrate forward strand, Intact 12RSS substrate reverse strand, ... 著者 Chuenchor, W, Chen, X, Kim, M.S, Gellert, M, Yang, W. 登録日 2018-02-24 公開日 2018-04-25 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (4.15 Å) 主引用文献 Cracking the DNA Code for V(D)J Recombination. Mol. Cell, 70, 2018
5D2I	4-oxalocrotonate decarboxylase from Pseudomonas putida G7 - complexed with calcium and acetate 分子名称: 1,2-ETHANEDIOL, 4-oxalocrotonate decarboxylase NahK, ACETATE ION, ... 著者 Guimaraes, S.L, Nagem, R.A.P. 登録日 2015-08-05 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Crystal Structures of Apo and Liganded 4-Oxalocrotonate Decarboxylase Uncover a Structural Basis for the Metal-Assisted Decarboxylation of a Vinylogous beta-Keto Acid. Biochemistry, 55, 2016
7AHU	Anti-FX Fab of mim8 in complex with human FXa 分子名称: Anti-FX Fab of mim8 heavy chain, Anti-FX Fab of mim8 light chain, CALCIUM ION, ... 著者 Johansson, E. 登録日 2020-09-25 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A factor VIIIa-mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice. Blood, 138, 2021
7AHV	Anti-FIXa Fab of mim8 in complex with human FIXa 分子名称: CALCIUM ION, Coagulation factor IX, L-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamide, ... 著者 Johansson, E. 登録日 2020-09-25 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 A factor VIIIa-mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice. Blood, 138, 2021
4W8L	Structure of GH10 from Paenibacillus barcinonensis 分子名称: CALCIUM ION, Endo-1,4-beta-xylanase C, GLYCEROL 著者 Sainz-Polo, M.A, Sanz-Aparicio, J. 登録日 2014-08-25 公開日 2015-06-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Exploring Multimodularity in Plant Cell Wall Deconstruction: STRUCTURAL AND FUNCTIONAL ANALYSIS OF Xyn10C CONTAINING THE CBM22-1-CBM22-2 TANDEM. J.Biol.Chem., 290, 2015
6CIK	Pre-Reaction Complex, RAG1(E962Q)/2-intact/nicked 12/23RSS complex in Mn2+ 分子名称: DNA (5'-D(*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3'), High mobility group protein B1, Intact 12RSS substrate forward strand, ... 著者 Chuenchor, W, Chen, X, Kim, M.S, Gellert, M, Yang, W. 登録日 2018-02-24 公開日 2018-04-25 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Cracking the DNA Code for V(D)J Recombination. Mol. Cell, 70, 2018
6CRM	Crystal Structure of RecQ catalytic core from C. sakazakii bound to an unfolded G-quadruplex 分子名称: DNA (5'-D(P*GP*GP*GP*TP*CP*GP*GP*TP*GP*CP*CP*TP*TP*A)-3'), RecQ, ZINC ION 著者 Voter, A.F, Keck, J.L. 登録日 2018-03-19 公開日 2018-10-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.19286251 Å) 主引用文献 A guanine-flipping and sequestration mechanism for G-quadruplex unwinding by RecQ helicases. Nat Commun, 9, 2018
5D2G	4-oxalocrotonate decarboxylase from Pseudomonas putida G7 - complexed with magnesium 分子名称: 1,2-ETHANEDIOL, 4-oxalocrotonate decarboxylase NahK, ACETATE ION, ... 著者 Guimaraes, S.L, Nagem, R.A.P. 登録日 2015-08-05 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.897 Å) 主引用文献 Crystal Structures of Apo and Liganded 4-Oxalocrotonate Decarboxylase Uncover a Structural Basis for the Metal-Assisted Decarboxylation of a Vinylogous beta-Keto Acid. Biochemistry, 55, 2016
5DBQ	Crystal structure of insect thioredoxin at 1.95 Angstroms 分子名称: Thioredoxin 著者 Klinke, S, Tejedor, M.D, Cerutti, M.L, Giacometti, R, Otero, L.H, Goldbaum, F.A, Zavala, J.A, Wolosiuk, R.A, Pagano, E.A. 登録日 2015-08-21 公開日 2016-08-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of insect thioredoxin at 1.95 Angstroms To Be Published
5DAE	Kazal type inhibitor from salivary glands of Aedes aegypti mosquito 分子名称: AAEL006007-PA 著者 Torquato, R.J.S, Pereira, P.J.B, Tanaka, A.S. 登録日 2015-08-19 公開日 2016-09-07 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 High-resolution structure of a Kazal-type serine protease inhibitor from the dengue vector Aedes aegypti. Acta Crystallogr F Struct Biol Commun, 73, 2017
5D2H	4-oxalocrotonate decarboxylase from Pseudomonas putida G7 - complexed with magnesium and alpha-ketoglutarate 分子名称: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, 4-oxalocrotonate decarboxylase NahK, ... 著者 Guimaraes, S.L, Nagem, R.A.P. 登録日 2015-08-05 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.936 Å) 主引用文献 Crystal Structures of Apo and Liganded 4-Oxalocrotonate Decarboxylase Uncover a Structural Basis for the Metal-Assisted Decarboxylation of a Vinylogous beta-Keto Acid. Biochemistry, 55, 2016
4YMQ	X-ray co-structure of nuclear receptor ROR-GAMMAT + SRC2 peptide with a benzothiadiazole dioxide inverse agonist 分子名称: 4-{3-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)benzyl]-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl}-N-[(2R)-4-hydroxybutan-2-yl]-N-methylbutanamide, GLYCEROL, Nuclear receptor ROR-gamma, ... 著者 li, X. 登録日 2015-03-07 公開日 2015-04-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of 1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxide analogs as new RORC modulators. Bioorg.Med.Chem.Lett., 25, 2015
2V95	Structure of Corticosteroid-Binding Globulin in complex with Cortisol 分子名称: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN 著者 Klieber, M.A, Muller, Y.A. 登録日 2007-08-21 公開日 2007-09-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Corticosteroid-Binding Globulin: Structural Basis for Steroid Transport and Proteinase-Triggered Release J.Biol.Chem., 282, 2007
8ADW	Lipidic alpha-synuclein fibril - polymorph L1C 分子名称: Alpha-synuclein 著者 Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. 登録日 2022-07-11 公開日 2022-10-12 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.95 Å) 主引用文献 The 3D structure of lipidic fibrils of alpha-synuclein. Nat Commun, 13, 2022
8ADU	Lipidic alpha-synuclein fibril - polymorph L1A 分子名称: Alpha-synuclein 著者 Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. 登録日 2022-07-11 公開日 2022-10-12 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.24 Å) 主引用文献 The 3D structure of lipidic fibrils of alpha-synuclein. Nat Commun, 13, 2022
8AEX	Lipidic alpha-synuclein fibril - polymorph L3A 分子名称: Alpha-synuclein 著者 Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. 登録日 2022-07-14 公開日 2022-10-12 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 The 3D structure of lipidic fibrils of alpha-synuclein. Nat Commun, 13, 2022
8ADV	Lipidic alpha-synuclein fibril - polymorph L1B 分子名称: Alpha-synuclein 著者 Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. 登録日 2022-07-11 公開日 2022-10-12 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.98 Å) 主引用文献 The 3D structure of lipidic fibrils of alpha-synuclein. Nat Commun, 13, 2022
9EUU	Structure of recombinant alpha-synuclein fibrils 1B capable of seeding GCIs in vivo 分子名称: Alpha-synuclein 著者 Burger, D, Kashyrina, M, Lewis, A, De Nuccio, F, Mohammed, I, de La Seigliere, H, van den Heuvel, L, Feuillie, C, Verchere, J, Berbon, M, Arotcarena, M, Retailleau, A, Bezard, E, Laferriere, F, Loquet, A, Bousset, L, Baron, T, Lofrumento, D.D, De Giorgi, F, Stahlberg, H, Ichas, F. 登録日 2024-03-28 公開日 2024-06-05 実験手法 ELECTRON MICROSCOPY (1.93 Å) 主引用文献 Multiple System Atrophy: Insights from aSyn Fibril Structure To Be Published
8ADS	Lipidic alpha-synuclein fibril - polymorph L2B 分子名称: Alpha-synuclein 著者 Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. 登録日 2022-07-11 公開日 2022-10-12 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.05 Å) 主引用文献 The 3D structure of lipidic fibrils of alpha-synuclein. Nat Commun, 13, 2022

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