PDB: 2461 件ウェブページステータス検索Chemie searchBIRD

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5NZV	The structure of the COPI coat linkage IV 分子名称: ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ... 著者 Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G. 登録日 2017-05-15 公開日 2017-06-28 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (17.299999 Å) 主引用文献 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. Elife, 6, 2017
5NZS	The structure of the COPI coat leaf in complex with the ArfGAP2 uncoating factor 分子名称: ADP-ribosylation factor 1, ADP-ribosylation factor GTPase-activating protein 2, Coatomer subunit alpha, ... 著者 Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G. 登録日 2017-05-15 公開日 2017-06-28 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (10.1 Å) 主引用文献 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. Elife, 6, 2017
5NZR	The structure of the COPI coat leaf 分子名称: ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ... 著者 Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G. 登録日 2017-05-15 公開日 2017-06-28 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (9.2 Å) 主引用文献 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. Elife, 6, 2017
5OA3	Human 40S-eIF2D-re-initiation complex 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Weisser, M, Schaefer, T, Leibundgut, M, Boehringer, D, Aylett, C.H.S, Ban, N. 登録日 2017-06-20 公開日 2017-08-09 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural and Functional Insights into Human Re-initiation Complexes. Mol. Cell, 67, 2017
3DXK	Structure of Bos Taurus Arp2/3 Complex with Bound Inhibitor CK0944636 分子名称: Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, Actin-related protein 2/3 complex subunit 2, ... 著者 Nolen, B.J, Tomasevic, N, Russell, A, Pierce, D.W, Jia, Z, Hartman, J, Sakowicz, R, Pollard, T.D. 登録日 2008-07-24 公開日 2009-07-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Characterization of two classes of small molecule inhibitors of Arp2/3 complex Nature, 460, 2009
3DWL	Crystal Structure of Fission Yeast Arp2/3 Complex Lacking the Arp2 Subunit 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2/3 complex subunit 1, Actin-related protein 2/3 complex subunit 2, ... 著者 Nolen, B.J, Pollard, T.D. 登録日 2008-07-22 公開日 2008-08-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.78 Å) 主引用文献 Structure and biochemical properties of fission yeast arp2/3 complex lacking the arp2 subunit. J.Biol.Chem., 283, 2008
5NZU	The structure of the COPI coat linkage II 分子名称: ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ... 著者 Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G. 登録日 2017-05-15 公開日 2017-06-28 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (15 Å) 主引用文献 9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. Elife, 6, 2017
3DXM	Structure of Bos taurus Arp2/3 Complex with Bound Inhibitor CK0993548 分子名称: (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ... 著者 Nolen, B.J, Tomasevic, N, Russell, A, Pierce, D.W, Jia, Z, Hartman, J, Sakowicz, R, Pollard, T.D. 登録日 2008-07-24 公開日 2009-07-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Characterization of two classes of small molecule inhibitors of Arp2/3 complex Nature, 460, 2009
3RSE	Structural and biochemical characterization of two binding sites for nucleation promoting factor WASp-VCA on Arp2/3 complex 分子名称: Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, Actin-related protein 2/3 complex subunit 2, ... 著者 Pollard, T.D, Jurgenson, C.T, Ti, S, Nolen, B.J. 登録日 2011-05-02 公開日 2011-06-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural and biochemical characterization of two binding sites for nucleation-promoting factor WASp-VCA on Arp2/3 complex. Proc.Natl.Acad.Sci.USA, 108, 2011
3SN6	Crystal structure of the beta2 adrenergic receptor-Gs protein complex 分子名称: 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Camelid antibody VHH fragment, Endolysin,Beta-2 adrenergic receptor, ... 著者 Rasmussen, S.G.F, DeVree, B.T, Zou, Y, Kruse, A.C, Chung, K.Y, Kobilka, T.S, Thian, F.S, Chae, P.S, Pardon, E, Calinski, D, Mathiesen, J.M, Shah, S.T.A, Lyons, J.A, Caffrey, M, Gellman, S.H, Steyaert, J, Skiniotis, G, Weis, W.I, Sunahara, R.K, Kobilka, B.K. 登録日 2011-06-28 公開日 2011-07-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structure of the beta2 adrenergic receptor-Gs protein complex Nature, 477, 2011
3UKU	Structure of Arp2/3 complex with bound inhibitor CK-869 分子名称: (2S)-2-(3-bromophenyl)-3-(2,4-dimethoxyphenyl)-1,3-thiazolidin-4-one, ACTIN-LIKE PROTEIN 2, ACTIN-LIKE PROTEIN 3, ... 著者 Nolen, B.J, Han, M. 登録日 2011-11-09 公開日 2013-02-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structure of Arp2/3 complex with bound inhibitor CK-869 To be Published
3V5W	Human G Protein-Coupled Receptor Kinase 2 in Complex with Soluble Gbetagamma Subunits and Paroxetine 分子名称: G-protein coupled receptor kinase 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Thal, D.M, Tesmer, J.J.G. 登録日 2011-12-17 公開日 2012-09-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Paroxetine is a direct inhibitor of g protein-coupled receptor kinase 2 and increases myocardial contractility. Acs Chem.Biol., 7, 2012
3ULE	Structure of Bos taurus Arp2/3 complex with bound inhibitor CK-869 and ATP 分子名称: (2S)-2-(3-bromophenyl)-3-(2,4-dimethoxyphenyl)-1,3-thiazolidin-4-one, ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, ... 著者 Nolen, B.J, Han, M. 登録日 2011-11-10 公開日 2013-02-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of Bos taurus Arp2/3 complex with bound inhibitor CK-869 and ATP To be Published
3UKR	Crystal structure of Bos taurus Arp2/3 complex with bound inhibitor CK-666 分子名称: 2-fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ... 著者 Nolen, B.J, Han, M. 登録日 2011-11-09 公開日 2013-02-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Structural characterization and computer-aided optimization of a small-molecule inhibitor of the Arp2/3 complex, a key regulator of the actin cytoskeleton. Chemmedchem, 7, 2012
3UZS	Structure of the C13.28 RNA Aptamer Bound to the G Protein-Coupled Receptor Kinase 2-Heterotrimeric G Protein Beta 1 and Gamma 2 Subunit Complex 分子名称: Beta-adrenergic receptor kinase 1, C13.28 RNA Aptamer, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Tesmer, J.J.G, Tesmer, V.M. 登録日 2011-12-07 公開日 2012-07-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (4.52 Å) 主引用文献 Molecular mechanism for inhibition of g protein-coupled receptor kinase 2 by a selective RNA aptamer. Structure, 20, 2012
4U50	Crystal structure of Verrucarin bound to the yeast 80S ribosome 分子名称: (4S,5R,10E,12Z,16R,16aS,17S,18R,19aR,23aR)-4-hydroxy-5,16a,21-trimethyl-4,5,6,7,16,16a,22,23-octahydro-3H,18H,19aH-spiro[16,18-methano[1,6,12]trioxacyclooctadecino[3,4-d]chromene-17,2'-oxirane]-3,9,14-trione, 18S ribosomal RNA, 25S ribosomal RNA, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U56	Crystal structure of Blasticidin S bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U4Y	Crystal structure of Pactamycin bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U52	Crystal structure of Nagilactone C bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U51	Crystal structure of Narciclasine bound to the yeast 80S ribosome 分子名称: (2S,3R,4S,4aR)-2,3,4,7-tetrahydroxy-3,4,4a,5-tetrahydro[1,3]dioxolo[4,5-j]phenanthridin-6(2H)-one, 18S ribosomal RNA, 25S ribosomal RNA, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U53	Crystal structure of Deoxynivalenol bound to the yeast 80S ribosome 分子名称: (3beta,7alpha)-3,7,15-trihydroxy-12,13-epoxytrichothec-9-en-8-one, 18S ribosomal RNA, 25S ribosomal RNA, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U4R	Crystal structure of Lactimidomycin bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 4-{(2R,5S,6E)-2-hydroxy-5-methyl-7-[(2R,3S,4E,6Z,10E)-3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl]-4-oxooct-6-en-1-yl}piperidine-2,6-dione, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.801 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U55	Crystal structure of Cryptopleurine bound to the yeast 80S ribosome 分子名称: (14aR)-2,3,6-trimethoxy-11,12,13,14,14a,15-hexahydro-9H-dibenzo[f,h]pyrido[1,2-b]isoquinoline, 18S ribosomal RNA, 25S ribosomal RNA, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U4Q	Crystal structure of Homoharringtonine bound to the yeast 80S ribosome 分子名称: (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 18S ribosomal RNA, 25S ribosomal RNA, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U4O	Crystal structure of Geneticin bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014

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