PDB: 1013 件ウェブページステータス検索Chemie searchBIRD

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8IWV	Crystal structure of BlaA-1 APO 分子名称: Beta-lactamase, PHOSPHATE ION 著者 Bhattacharya, S, Hazra, S. 登録日 2023-03-31 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of BlaA-1 APO To be published
8IY4	Crystal structure of Class A beta-lactamase BlaA WT - complex with Meropenem 分子名称: (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase, PHOSPHATE ION 著者 Bhattacharya, S, Hazra, S. 登録日 2023-04-03 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of Class A beta-lactamase BlaA WT - complex with Meropenem To be published
8IX8	Crystal structure of Class A beta-lactamase BlaA WT - complex with Tebipenem 分子名称: (4R,5S)-3-(1-(4,5-dihydrothiazol-2-yl)azetidin-3-ylthio)-5-((2S,3R)-3-hydroxy-1-oxobutan-2-yl)-4-methyl-4,5- dihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase, PHOSPHATE ION 著者 Bhattacharya, S, Hazra, S. 登録日 2023-03-31 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of Class A beta-lactamase BlaA WT - complex with Tebipenem To be published
8IXX	Crystal structure of Class A beta-lactamase BlaA WT - complex with Ertapenem 分子名称: (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase, PHOSPHATE ION 著者 Bhattacharya, S, Hazra, S. 登録日 2023-04-03 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of Class A beta-lactamase BlaA WT - complex with Ertapenem To be published
8J6Y	Crystal structure of class A beta-lactamase PSE-4 WT- Apo state 分子名称: Beta-lactamase PSE-4, SULFATE ION 著者 Sarkar, M, Bhattacharya, S, Hazra, S. 登録日 2023-04-26 公開日 2024-05-01 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of class A beta-lactamase PSE-4 WT- Apo state To be published
8JK3	Crystal Structure of Bel-1 Extended Spectrum Beta-lactamase in Hexagonal Form 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Beta-lactamase, ... 著者 Dhankhar, K, Hazra, S. 登録日 2023-05-31 公開日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of Bel-1 ESBL in Hexagonal Form To Be Published
5FAP	CTX-M-15 in complex with FPI-1602 分子名称: Beta-lactamase, [[(3~{R},6~{S})-6-[(azetidin-3-ylcarbonylamino)carbamoyl]-1-methanoyl-piperidin-3-yl]amino] hydrogen sulfate 著者 King, A.M, King, D.T, French, S, Brouillette, E, Asli, A, Alexander, A.N, Vuckovic, M, Maiti, S.N, Parr, T.R, Brown, E.D, Malouin, F, Strynadka, N.C.J, Wright, G.D. 登録日 2015-12-11 公開日 2016-01-20 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-beta-Lactamases and Penicillin-Binding Proteins. Acs Chem.Biol., 11, 2016
8OE5	Structure of P167S BlaC from Mycobacterium tuberculosis at pH 6.3 分子名称: Beta-lactamase, CITRATE ANION, GLYCEROL 著者 Sun, J, Chikunova, A, Ubbink, M. 登録日 2023-03-10 公開日 2023-08-23 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Enhanced activity against a third-generation cephalosporin by destabilization of the active site of a class A beta-lactamase. Int.J.Biol.Macromol., 250, 2023
8OE1	Structure of P167S BlaC from Mycobacterium tuberculosis at pH 5 分子名称: Beta-lactamase, GLYCEROL 著者 Sun, J, Chikunova, A, Ubbink, M. 登録日 2023-03-10 公開日 2023-08-23 最終更新日 2024-10-02 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Enhanced activity against a third-generation cephalosporin by destabilization of the active site of a class A beta-lactamase. Int.J.Biol.Macromol., 250, 2023
5G18	Direct Observation of Active-site Protonation States in a Class A beta lactamase with a monobactam substrate 分子名称: 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-oxo-2-{[(2S,3S)-1-oxo-3-(sulfoamino)butan-2-yl]amino}ethylidene]amino}oxy)-2-methylpropanoic acid, BETA-LACTAMASE CTX-M-97, SULFATE ION 著者 Vandavasi, V.G, Weiss, K.L, Parks, J.M, Cooper, J.B, Ginell, S.L, Coates, L. 登録日 2016-03-23 公開日 2016-11-09 最終更新日 2019-10-23 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Active-Site Protonation States in an Acyl-Enzyme Intermediate of a Class A beta-Lactamase with a Monobactam Substrate. Antimicrob. Agents Chemother., 61, 2017
5GLC	Crystal structure of the class A beta-lactamase PenL-tTR11 containing 20 residues insertion in omega-loop 分子名称: Beta-lactamase 著者 Choi, J.M, Yi, H, Kim, H.S, Lee, S.H. 登録日 2016-07-10 公開日 2017-02-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.601 Å) 主引用文献 High adaptability of the omega loop underlies the substrate-spectrum-extension evolution of a class A beta-lactamase, PenL Sci Rep, 6, 2016
5GLD	Crystal structure of the class A beta-lactamase PenL-tTR11 in complex with CBA 分子名称: Beta-lactamase, PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE 著者 Choi, J.M, Yi, H, Kim, H.S, Lee, S.H. 登録日 2016-07-10 公開日 2017-02-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 High adaptability of the omega loop underlies the substrate-spectrum-extension evolution of a class A beta-lactamase, PenL Sci Rep, 6, 2016
5GL9	Crystal structure of the class A beta-lactamase PenL 分子名称: Beta-lactamase, GLYCEROL 著者 Choi, J.M, Yi, H, Kim, H.S, Lee, S.H. 登録日 2016-07-10 公開日 2017-02-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 High adaptability of the omega loop underlies the substrate-spectrum-extension evolution of a class A beta-lactamase, PenL Sci Rep, 6, 2016
5GLA	Crystal structure of the class A beta-lactamase PenL-tTR10 containing 10 residues insertion in omega-loop 分子名称: Beta-lactamase 著者 Choi, J.M, Yi, H, Kim, H.S, Lee, S.H. 登録日 2016-07-10 公開日 2017-02-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 High adaptability of the omega loop underlies the substrate-spectrum-extension evolution of a class A beta-lactamase, PenL Sci Rep, 6, 2016
8JOI	Crystal Structure of Bel-1 E166A Mutant. 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BROMIDE ION, Beta-lactamase, ... 著者 Dhankhar, K, Hazra, S. 登録日 2023-06-07 公開日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of Bel-1 E166A Mutant To Be Published
5GLB	Crystal structure of the class A beta-lactamase PenL-tTR10 in complex with CBA 分子名称: Beta-lactamase, PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE 著者 Choi, J.M, Yi, H, Kim, H.S, Lee, S.H. 登録日 2016-07-10 公開日 2017-02-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 High adaptability of the omega loop underlies the substrate-spectrum-extension evolution of a class A beta-lactamase, PenL Sci Rep, 6, 2016
5FA7	CTX-M-15 in complex with FPI-1523 分子名称: Beta-lactamase, [[(3~{R},6~{S})-6-(acetamidocarbamoyl)-1-methanoyl-piperidin-3-yl]amino] hydrogen sulfate 著者 King, A.M, King, D.T, French, S, Brouillette, E, Asli, A, Alexander, A.N, Vuckovic, M, Maiti, S.N, Parr, T.R, Brown, E.D, Malouin, F, Strynadka, N.C.J, Wright, G.D. 登録日 2015-12-11 公開日 2016-01-20 最終更新日 2019-11-20 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-beta-Lactamases and Penicillin-Binding Proteins. Acs Chem.Biol., 11, 2016
5HW3	Crystal structure of a beta lactamase from Burkholderia vietnamiensis 分子名称: ACETATE ION, Beta-lactamase, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-01-29 公開日 2016-02-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal structure of a beta lactamase from Burkholderia vietnamiensis to be published
5F83	Imipenem complex of the GES-5 C69G mutant 分子名称: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase 著者 Smith, C.A, Vakulenko, S.B. 登録日 2015-12-09 公開日 2016-09-07 最終更新日 2019-12-11 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Role of the Conserved Disulfide Bridge in Class A Carbapenemases. J.Biol.Chem., 291, 2016
8PCD	Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 150 ms 分子名称: BORATE ION, Beta-lactamase, SULFATE ION 著者 Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. 登録日 2023-06-11 公開日 2024-06-26 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
8PCF	Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 500 ms 分子名称: BORATE ION, Beta-lactamase, SULFATE ION 著者 Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. 登録日 2023-06-11 公開日 2024-06-26 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
8PCK	Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 0 ms 分子名称: BORATE ION, Beta-lactamase, SULFATE ION 著者 Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. 登録日 2023-06-11 公開日 2024-06-26 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
8PCJ	Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid, 10000 ms 分子名称: BORATE ION, Beta-lactamase, SULFATE ION 著者 Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. 登録日 2023-06-11 公開日 2024-06-26 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
8PCL	Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 50 ms 分子名称: BORATE ION, Beta-lactamase, SULFATE ION, ... 著者 Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. 登録日 2023-06-11 公開日 2024-06-26 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
8PCR	Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 750 ms 分子名称: BORATE ION, Beta-lactamase, SULFATE ION, ... 著者 Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. 登録日 2023-06-11 公開日 2024-06-26 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024

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