PDB: 2624 件ウェブページステータス検索Chemie searchBIRD

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6FKO	Deoxyguanylosuccinate synthase (DgsS) quaternary structure with ATP, dGMP, hadacidin at 2.1 Angstrom resolution 分子名称: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Adenylosuccinate synthetase, ... 著者 Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A. 登録日 2018-01-24 公開日 2019-06-26 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Deoxyguanylosuccinate synthase (DgsS) quaternary structure with ATP, dGMP, HAdacidin at 2.1 Angstrom resolution To Be Published
2HRY	T. maritima PurL complexed with AMPPCP 分子名称: MAGNESIUM ION, PHOSPHATE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... 著者 Ealick, S.E, Morar, M. 登録日 2006-07-20 公開日 2007-01-09 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily Biochemistry, 45, 2006
1M0T	Yeast Glutathione Synthase 分子名称: SULFATE ION, glutathione synthetase 著者 Gogos, A, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2002-06-14 公開日 2002-12-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Large Conformational Changes in the Catalytic Cycle of Glutathione Synthase Structure, 10, 2002
3E60	Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase II from Bartonella henselae 分子名称: 3-oxoacyl-[acyl-carrier-protein ] synthase II, POTASSIUM ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2008-08-14 公開日 2008-08-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase II from Bartonella henselae To be Published
2HS4	T. maritima PurL complexed with FGAR and AMPPCP 分子名称: MAGNESIUM ION, N-(N-FORMYLGLYCYL)-5-O-PHOSPHONO-BETA-D-RIBOFURANOSYLAMINE, PHOSPHATE ION, ... 著者 Ealick, S.E, Morar, M. 登録日 2006-07-21 公開日 2007-01-09 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily Biochemistry, 45, 2006
2HS3	T. maritima PurL complexed with FGAR 分子名称: N-(N-FORMYLGLYCYL)-5-O-PHOSPHONO-BETA-D-RIBOFURANOSYLAMINE, PHOSPHATE ION, Phosphoribosylformylglycinamidine synthase II 著者 Ealick, S.E, Morar, M. 登録日 2006-07-21 公開日 2007-01-09 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily Biochemistry, 45, 2006
2HRU	T. maritima PurL complexed with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Phosphoribosylformylglycinamidine synthase II 著者 Ealick, S.E, Morar, M. 登録日 2006-07-20 公開日 2007-01-09 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily Biochemistry, 45, 2006
6NOP	Structure of Cyanothece McdA(D38A)-ATP complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cobyrinic acid ac-diamide synthase, MAGNESIUM ION 著者 Schumacher, M.A. 登録日 2019-01-16 公開日 2019-04-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structures of maintenance of carboxysome distribution Walker-box McdA and McdB adaptor homologs. Nucleic Acids Res., 47, 2019
5T8T	Crystal Structure of a S-adenosylmethionine Synthase from Neisseria gonorrhoeae with bound AMP and Magnesium 分子名称: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, S-adenosylmethionine synthase 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-09-08 公開日 2016-09-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of a S-adenosylmethionine Synthase from Neisseria gonorrhoeae with bound AMP and Magnesium to be published
6K5V	Structure of CSY4 Apo-form 分子名称: CHLORIDE ION, Citrate synthase 4, mitochondrial 著者 Nishio, K, Mizushima, T. 登録日 2019-05-31 公開日 2020-03-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Structural and biochemical characterization of mitochondrial citrate synthase 4 from Arabidopsis thaliana. Acta Crystallogr.,Sect.F, 76, 2020
4ACD	GSK3b in complex with inhibitor 分子名称: 3-AMINO-6-{4-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-N-PYRIDIN-3-YLPYRAZINE-2-CARBOXAMIDE, GLYCOGEN SYNTHASE KINASE-3 BETA 著者 Xue, Y, Ormo, M. 登録日 2011-12-15 公開日 2012-05-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines. J. Med. Chem., 55, 2012
4ACH	GSK3b in complex with inhibitor 分子名称: 3-AMINO-N-(3-METHOXYPROPYL)-6-{4-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}PYRAZINE-2-CARBOXAMIDE, GLYCOGEN SYNTHASE KINASE-3 BETA 著者 Xue, Y, Ormo, M. 登録日 2011-12-15 公開日 2012-05-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines. J. Med. Chem., 55, 2012
5HLP	X-RAY CRYSTAL STRUCTURE OF GSK3B IN COMPLEX WITH BRD3937 分子名称: 4-(2-methoxyphenyl)-3,7,7-trimethyl-1,6,7,8-tetrahydro-5H-pyrazolo[3,4-b]quinolin-5-one, Glycogen synthase kinase-3 beta 著者 White, A, Lakshminarasimhan, D, Nadupalli, A, Suto, R.K. 登録日 2016-01-15 公開日 2016-05-25 最終更新日 2016-07-27 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects. Acs Chem.Biol., 11, 2016
4ACG	GSK3b in complex with inhibitor 分子名称: 2-AMINO-5-{4-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-N-[4-(PYRROLIDIN-1-YLMETHYL)PYRIDIN-3-YL]PYRIDINE-3-CARBOXAMIDE, GLYCOGEN SYNTHASE KINASE-3 BETA 著者 Xue, Y, Ormo, M. 登録日 2011-12-15 公開日 2012-05-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines. J. Med. Chem., 55, 2012
4ACC	GSK3b in complex with inhibitor 分子名称: 3-AMINO-6-(4-{[2-(DIMETHYLAMINO)ETHYL]SULFAMOYL}PHENYL)-N-PYRIDIN-3-YLPYRAZINE-2-CARBOXAMIDE, DIMETHYL SULFOXIDE, GLYCOGEN SYNTHASE KINASE-3 BETA 著者 Xue, Y, Ormo, M. 登録日 2011-12-14 公開日 2012-05-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines. J. Med. Chem., 55, 2012
5HLN	X-RAY CRYSTAL STRUCTURE OF GSK3B IN COMPLEX WITH CHIR99021 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHIR99021, Glycogen synthase kinase-3 beta, ... 著者 White, A, Lakshminarasimhan, D, Nadupalli, A, Suto, R.K. 登録日 2016-01-15 公開日 2016-05-25 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects. Acs Chem.Biol., 11, 2016
6PK4	cryoEM structure of the substrate-bound human CTP synthase 2 filament 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CTP synthase 2, URIDINE 5'-TRIPHOSPHATE 著者 Lynch, E.M, Kollman, J.M. 登録日 2019-06-28 公開日 2019-12-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Coupled structural transitions enable highly cooperative regulation of human CTPS2 filaments. Nat.Struct.Mol.Biol., 27, 2020
3ETH	Crystal structure of E. coli Purk in complex with MgATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Phosphoribosylaminoimidazole carboxylase ATPase subunit 著者 Holden, H.M, Thoden, J.B. 登録日 2008-10-08 公開日 2008-10-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural analysis of the active site geometry of N(5)-Carboxyaminoimidazole ribonucleotide synthetase from Escherichia coli. Biochemistry, 47, 2008
3SAY	Crystal structure of human glycogen synthase kinase 3 beta (GSK3b) in complex with inhibitor 142 分子名称: (3Z)-N,N-diethyl-3-[(3E)-3-(hydroxyimino)-1,3-dihydro-2H-indol-2-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide, (4S)-2-METHYL-2,4-PENTANEDIOL, FORMIC ACID, ... 著者 Mazanetz, M.P, Cheng, R.K.Y, Rowan, F, Laughton, C.A, Barker, J.J, Fischer, P.M. 登録日 2011-06-03 公開日 2012-06-13 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.231 Å) 主引用文献 Crystal structure of human glycogen synthase kinase 3 beta (GSK3b) in complex with inhibitor 142 To be Published
7UTT	Structure of Non-hydrolyzable ATP (ApCpp) binds to Cyclic GMP AMP synthase (cGAS) through Mn coordination 分子名称: Cyclic GMP-AMP synthase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MANGANESE (II) ION, ... 著者 Wu, S, Gabelli, S.B, Sohn, J. 登録日 2022-04-27 公開日 2023-05-03 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structure of Non-hydrolyzable ATP (ApCpp) binds to Cyclic GMP AMP synthase (cGAS) through Mn coordination To Be Published
7WAF	Trichodesmium erythraeum cyanophycin synthetase 1 (TeCphA1) with ATPgammaS and 4x(beta-Asp-Arg) 分子名称: 4x(beta-Asp-Arg), ARGININE, Cyanophycin synthase, ... 著者 Miyakawa, T, Yang, J, Kawasaki, M, Adachi, N, Fujii, A, Miyauchi, Y, Muramatsu, T, Moriya, T, Senda, T, Tanokura, M. 登録日 2021-12-14 公開日 2022-09-07 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (2.52 Å) 主引用文献 Structural bases for aspartate recognition and polymerization efficiency of cyanobacterial cyanophycin synthetase. Nat Commun, 13, 2022
7WAD	Trichodesmium erythraeum cyanophycin synthetase 1 (TeCphA1) with ATPgammaS 分子名称: Cyanophycin synthase, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER 著者 Kawasaki, M, Miyakawa, T, Yang, J, Adachi, N, Fujii, A, Miyauchi, Y, Muramatsu, T, Moriya, T, Senda, T, Tanokura, M. 登録日 2021-12-14 公開日 2022-09-07 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (2.96 Å) 主引用文献 Structural bases for aspartate recognition and polymerization efficiency of cyanobacterial cyanophycin synthetase. Nat Commun, 13, 2022
7WAE	Trichodesmium erythraeum cyanophycin synthetase 1 (TeCphA1) with ATPgammaS, 4x(beta-Asp-Arg), and aspartate 分子名称: 4x(beta-Asp-Arg), ARGININE, ASPARTIC ACID, ... 著者 Miyakawa, T, Yang, J, Kawasaki, M, Adachi, N, Fujii, A, Miyauchi, Y, Muramatsu, T, Moriya, T, Senda, T, Tanokura, M. 登録日 2021-12-14 公開日 2022-09-07 最終更新日 2022-09-14 実験手法 ELECTRON MICROSCOPY (2.64 Å) 主引用文献 Structural bases for aspartate recognition and polymerization efficiency of cyanobacterial cyanophycin synthetase. Nat Commun, 13, 2022
3GB2	GSK3beta inhibitor complex 分子名称: 2-methyl-5-(3-{4-[(S)-methylsulfinyl]phenyl}-1-benzofuran-5-yl)-1,3,4-oxadiazole, Glycogen synthase kinase-3 beta 著者 Mol, C.D. 登録日 2009-02-18 公開日 2010-03-02 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 2-{3-[4-(Alkylsulfinyl)phenyl]-1-benzofuran-5-yl}-5-methyl-1,3,4-oxadiazole derivatives as novel inhibitors of glycogen synthase kinase-3beta with good brain permeability. J.Med.Chem., 52, 2009
4M9U	The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 分子名称: ACETATE ION, CHLORIDE ION, FORMIC ACID, ... 著者 Tan, K, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2013-08-15 公開日 2013-08-28 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.599 Å) 主引用文献 The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 To be Published

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