6DNE
 
 | | Crystal structure of human Bromodomain-containing protein 4 (BRD4) bromodomain with MS660 | | 分子名称: | Bromodomain-containing protein 4, N,N'-[ethane-1,2-diylbis(oxyethane-2,1-diyl)]bis{2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetamide} | | 著者 | Ren, C, Zhou, M.M. | | 登録日 | 2018-06-06 | | 公開日 | 2018-07-18 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.958 Å) | | 主引用文献 | Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6R1E
 | | Structure of dodecin from Streptomyces coelicolor | | 分子名称: | CHLORIDE ION, COENZYME A, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Essen, L.-O, Sander, B. | | 登録日 | 2019-03-14 | | 公開日 | 2019-03-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Comparative biochemical and structural analysis of the flavin-binding dodecins fromStreptomyces davaonensisandStreptomyces coelicolorreveals striking differences with regard to multimerization.
Microbiology (Reading, Engl.), 165, 2019
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6D7K
 | | Complex structure of Methane monooxygenase hydroxylase in complex with inhibitory subunit | | 分子名称: | FE (III) ION, FORMIC ACID, HEXANE-1,6-DIOL, ... | | 著者 | Kim, H, Lee, S.J, Cho, U.-S. | | 登録日 | 2018-04-24 | | 公開日 | 2019-06-26 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | MMOD-induced structural changes of hydroxylase in soluble methane monooxygenase.
Sci Adv, 5, 2019
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6D8D
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3LMU
 | | Crystal structure of DTD from Plasmodium falciparum | | 分子名称: | D-tyrosyl-tRNA(Tyr) deacylase, IODIDE ION | | 著者 | Manickam, Y, Bhatt, T.K, Khan, S, Sharma, A. | | 登録日 | 2010-02-01 | | 公開日 | 2010-03-02 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of D-tyrosyl-tRNATyr deacylase using home-source Cu Kalpha and moderate-quality iodide-SAD data: structural polymorphism and HEPES-bound enzyme states
Acta Crystallogr.,Sect.D, 66, 2010
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6R40
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3L9B
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6R41
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6DND
 | | Crystal structure of wild-type (WT) human Glutamate oxaloacetate transaminase 1 (GOT1) | | 分子名称: | Aspartate aminotransferase, cytoplasmic, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Assar, Z, Holt, M.C, Stein, A.J, Lairson, L, Lyssiotis, C.A. | | 登録日 | 2018-06-06 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Biochemical Characterization and Structure-Based Mutational Analysis Provide Insight into the Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors.
Biochemistry, 57, 2018
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3LJ9
 | | X-ray structure of the iron superoxide dismutase from pseudoalteromonas haloplanktis in complex with sodium azide | | 分子名称: | AZIDE ION, FE (III) ION, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, ... | | 著者 | Merlino, A, Russo Krauss, I, Rossi, B, Conte, M, Vergara, A, Sica, F. | | 登録日 | 2010-01-26 | | 公開日 | 2010-09-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure and flexibility in cold-adapted iron superoxide dismutases: the case of the enzyme isolated from Pseudoalteromonas haloplanktis.
J.Struct.Biol., 172, 2010
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5I1E
 | | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-53/IGKV1-39 | | 分子名称: | FAB HEAVY CHAIN, FAB LIGHT CHAIN, GLYCEROL, ... | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | | 登録日 | 2016-02-05 | | 公開日 | 2016-06-08 | | 最終更新日 | 2016-08-03 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural diversity in a human antibody germline library.
Mabs, 8, 2016
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3V9P
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5I1H
 | | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-53/IGKV3-20 | | 分子名称: | FAB HEAVY CHAIN, FAB LIGHT CHAIN, SULFATE ION | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | | 登録日 | 2016-02-05 | | 公開日 | 2016-06-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.222 Å) | | 主引用文献 | Structural diversity in a human antibody germline library.
Mabs, 8, 2016
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2ZO6
 | | Crystal Structure of Kusabira-Cyan (KCY), a Cyan-Emitting GFP-Like Protein | | 分子名称: | CYAN-EMITTING GFP-LIKE PROTEIN, KUSABIRA-CYAN (KCY) | | 著者 | Kikuchi, A, Fukumura, E, Karasawa, S, Miyawaki, A, Shiro, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2008-05-06 | | 公開日 | 2009-05-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal structure of a new cyan fluorescent protein and its hue-shifted variants
Biochemistry, 48, 2009
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5I18
 | | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV1-69/IGKV4-1 | | 分子名称: | FAB HEAVY CHAIN, FAB LIGHT CHAIN, GLYCEROL | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | | 登録日 | 2016-02-05 | | 公開日 | 2016-02-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Structural diversity in a human antibody germline library.
Mabs, 8, 2016
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5I1K
 | | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV5-51/IGKV3-20 | | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, FAB HEAVY CHAIN, FAB LIGHT CHAIN, ... | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | | 登録日 | 2016-02-05 | | 公開日 | 2016-06-08 | | 最終更新日 | 2016-08-03 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural diversity in a human antibody germline library.
Mabs, 8, 2016
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5I1G
 | | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-53/IGKV3-11 | | 分子名称: | FAB HEAVY CHAIN, FAB LIGHT CHAIN, SULFATE ION | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | | 登録日 | 2016-02-05 | | 公開日 | 2016-06-08 | | 最終更新日 | 2016-08-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural diversity in a human antibody germline library.
Mabs, 8, 2016
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5I19
 | | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-23/IGKV1-39 | | 分子名称: | FAB HEAVY CHAIN, FAB LIGHT CHAIN | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | | 登録日 | 2016-02-05 | | 公開日 | 2016-06-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural diversity in a human antibody germline library.
Mabs, 8, 2016
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5I1J
 | | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV5-51/IGKV3-11 | | 分子名称: | FAB HEAVY CHAIN, FAB LIGHT CHAIN, GLYCEROL | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | | 登録日 | 2016-02-05 | | 公開日 | 2016-06-08 | | 最終更新日 | 2016-08-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural diversity in a human antibody germline library.
Mabs, 8, 2016
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5ID1
 | | Cetuximab Fab in complex with MPT-Cys meditope | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab heavy chain, Cetuximab Fab light chain, ... | | 著者 | Bzymek, K.P, Williams, J.C. | | 登録日 | 2016-02-23 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
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5ICX
 | | Cetuximab Fab in complex with CQFDLSTRRLRCGGSK meditope | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab heavy chain, Cetuximab Fab light chain, ... | | 著者 | Bzymek, K.P, Williams, J.C. | | 登録日 | 2016-02-23 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
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4HUP
 | | Structure of ricin A chain bound with N-(N-(pterin-7-yl)carbonylglycyl)-L-phenylalanyl)-L-phenylalanine | | 分子名称: | (2S)-2-[[(2S)-2-[2-[(2-azanyl-4-oxidanylidene-1H-pteridin-7-yl)carbonylamino]ethanoylamino]-3-phenyl-propanoyl]amino]-3-phenyl-propanoic acid, MALONIC ACID, Ricin, ... | | 著者 | Jasheway, K.R, Monzingo, A.F, Saito, R, Pruet, J.M, Manzano, L.A, Wiget, P.A, Anslyn, E.V, Robertus, J.D. | | 登録日 | 2012-11-02 | | 公開日 | 2012-12-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.699 Å) | | 主引用文献 | Peptide-conjugated pterins as inhibitors of ricin toxin A.
J.Med.Chem., 56, 2013
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5I1I
 | | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-53/IGKV4-1 | | 分子名称: | FAB HEAVY CHAIN, FAB LIGHT CHAIN | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | | 登録日 | 2016-02-05 | | 公開日 | 2016-06-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural diversity in a human antibody germline library.
Mabs, 8, 2016
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5ID0
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5I1L
 | | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV5-51/IGKV4-1 | | 分子名称: | FAB HEAVY CHAIN, FAB LIGHT CHAIN, GLYCEROL | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | | 登録日 | 2016-02-05 | | 公開日 | 2016-06-08 | | 最終更新日 | 2016-08-03 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural diversity in a human antibody germline library.
Mabs, 8, 2016
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