8X1H
 
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8W0C
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9BUN
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8YA1
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8TX5
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8WRA
 | | The Crystal Structure of CASP1 from Biortus | | 分子名称: | 1,2-ETHANEDIOL, Caspase-1 | | 著者 | Wang, F, Cheng, W, Yuan, Z, Lin, D, Guo, S. | | 登録日 | 2023-10-13 | | 公開日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | The Crystal Structure of CASP1 from Biortus.
To Be Published
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8UAS
 | | Rhodococcus ruber Alcohol Dehydrogenase NADH Biomimetic Complex - Compound 1a | | 分子名称: | 1-[3-[~{tert}-butyl(dimethyl)silyl]oxypropyl]pyridine-3-carboxamide, CITRIC ACID, ISOPROPYL ALCOHOL, ... | | 著者 | Wilson, L.A, Guddat, L.W, Schenk, G, Scott, C. | | 登録日 | 2023-09-22 | | 公開日 | 2024-07-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Characterization of Enzymatic Interactions with Functional Nicotinamide Cofactor Biomimetics
Catalysts, 14, 2024
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9FEB
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8X2S
 | | The Crystal Structure of BPGM from Biortus | | 分子名称: | 1,2-ETHANEDIOL, Bisphosphoglycerate mutase | | 著者 | Wang, F, Cheng, W, Yuan, Z, Qi, J, Li, J. | | 登録日 | 2023-11-10 | | 公開日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Crystal Structure of BPGM from Biortus
To Be Published
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8UAJ
 | | Succinate Bound Crystal Structure of Thermus scotoductus SA-01 Ene-reductase | | 分子名称: | FLAVIN MONONUCLEOTIDE, NADPH dehydrogenase, SUCCINIC ACID | | 著者 | Wilson, L.A, Guddat, L, Schenk, G, Scott, C. | | 登録日 | 2023-09-21 | | 公開日 | 2024-07-03 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Structural Characterization of Enzymatic Interactions with Functional Nicotinamide Cofactor Biomimetics
Catalysts, 14, 2024
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8VJ2
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9EU6
 | | The FK1 domain of FKBP51 in complex with SAFit-analog 23j | | 分子名称: | (1,5-dimethylpyrazol-4-yl)methyl (2~{S})-1-[(2~{S})-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)ethanoyl]piperidine-2-carboxylate, Peptidyl-prolyl cis-trans isomerase FKBP5 | | 著者 | Meyners, C, Buffa, V, Hausch, F. | | 登録日 | 2024-03-27 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | 1,4-Pyrazolyl-containing SAFit-analogues are selective FKBP51 inhibitors with improved ligand efficiency and drug-like profile.
Chemmedchem, 2024
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8XE7
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8YQ4
 | | Structure of mBaoJin2 | | 分子名称: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | | 著者 | Boyko, K.M, Nikolaeva, A.Y, Minyaev, M.E, Kuzmicheva, T.P, Vlaskina, A.V, Popov, V.O, Pyatkevich, K.D, Subach, F.V. | | 登録日 | 2024-03-19 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of mBaoJin2
To Be Published
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9EU7
 | | The FK1 domain of FKBP51 in complex with SAFit-analog 15b | | 分子名称: | (2-methyl-1,3-thiazol-5-yl)methyl (2S)-1-[(2S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)ethanoyl]piperidine-2-carboxylate, Peptidyl-prolyl cis-trans isomerase FKBP5 | | 著者 | Meyners, C, Buffa, V, Hausch, F. | | 登録日 | 2024-03-27 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | 1,4-Pyrazolyl-containing SAFit-analogues are selective FKBP51 inhibitors with improved ligand efficiency and drug-like profile.
Chemmedchem, 2024
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8ZN3
 | | Structure of Phosphopantetheine adenylyltransferase (PPAT) from Enterobacter sp. with the expression tag bound in the substrate binding site of a neighbouring molecule at 2.41 A resolution. | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, PHOSPHONOACETIC ACID, ... | | 著者 | Ahmad, N, Sharma, P, Bhushan, A, Sharma, S, Singh, T.P. | | 登録日 | 2024-05-25 | | 公開日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Structure of Phosphopantetheine adenylyltransferase (PPAT) from Enterobacter sp. with the expression tag bound in the substrate binding site of a neighbouring molecule at 2.41 A resolution.
To Be Published
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8WAB
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8UKV
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8UVL
 | | Crystal structure of selective IRE1a inhibitor 29 at the enzyme active site | | 分子名称: | 1,2-ETHANEDIOL, 1-phenyl-N-(2,3,6-trifluoro-4-{[(3M)-3-(2-{[(3R,5R)-5-fluoropiperidin-3-yl]amino}pyrimidin-4-yl)pyridin-2-yl]oxy}phenyl)methanesulfonamide, Serine/threonine-protein kinase/endoribonuclease IRE1 | | 著者 | Kiefer, J.R, Wallweber, H.A, Braun, M.-G, Wei, W, Jiang, F, Wang, W, Rudolph, J, Ashkenazi, A. | | 登録日 | 2023-11-03 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | Discovery of Potent, Selective, and Orally Available IRE1 alpha Inhibitors Demonstrating Comparable PD Modulation to IRE1 Knockdown in a Multiple Myeloma Model.
J.Med.Chem., 67, 2024
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8VEX
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8YYR
 | | Structure of the HitB T293G mutant | | 分子名称: | Putative ATP-dependent b-aminoacyl-ACP synthetase, [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-[(3~{S})-3-azanyl-3-(2-bromophenyl)propanoyl]sulfamate | | 著者 | Wang, D, Miyanaga, A, Chisuga, T, Kudo, F, Eguchi, T. | | 登録日 | 2024-04-04 | | 公開日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Engineering the Substrate Specificity of (S)-beta-Phenylalanine Adenylation Enzyme HitB.
Chembiochem, 2024
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8Y33
 | | A near-infrared fluorescent protein of de novo backbone design | | 分子名称: | 3-[5-[(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-2-[[5-[(3-ethyl-4-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, near-infrared fluorescent protein | | 著者 | Hu, X, Xu, Y. | | 登録日 | 2024-01-28 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Using Protein Design and Directed Evolution to Monomerize a Bright Near-Infrared Fluorescent Protein.
Acs Synth Biol, 13, 2024
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8VEY
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8X2R
 | | The Crystal Structure of HSP 90-alpha from Biortus. | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Heat shock protein HSP 90-alpha | | 著者 | Wang, F, Cheng, W, Lv, Z, Meng, Q, Lu, Y. | | 登録日 | 2023-11-10 | | 公開日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | The Crystal Structure of HSP 90-alpha from Biortus.
To Be Published
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9BJL
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