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5GAH
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BU of 5gah by Molmil
RNC in complex with SRP with detached NG domain
分子名称: 1A9L SS, 23S rRNA, 50S ribosomal protein L10, ...
著者Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N.
登録日2015-11-26
公開日2016-01-27
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon.
Nat Commun, 7, 2016
4WXG
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BU of 4wxg by Molmil
Crystal structure of L-Serine Hydroxymethyltransferase in complex with a mixture of L-Threonine and Glycine
分子名称: GLYCEROL, N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-threonine, SODIUM ION, ...
著者Hernandez, K, Zelen, I, Petrillo, G, Uson, I, Wandtke, C, Bujons, J, Joglar, J, Parella, T, Clapes, P.
登録日2014-11-13
公開日2015-02-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Engineered L-Serine Hydroxymethyltransferase from Streptococcus thermophilus for the Synthesis of alpha , alpha-Dialkyl-alpha-Amino Acids.
Angew.Chem.Int.Ed.Engl., 54, 2015
7P6X
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BU of 7p6x by Molmil
Cryo-Em structure of the hexameric RUVBL1-RUVBL2 in complex with ZNHIT2
分子名称: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2
著者Llorca, O, Serna, M, Fernandez-Leiro, R.
登録日2021-07-18
公開日2021-12-15
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献CryoEM of RUVBL1-RUVBL2-ZNHIT2, a complex that interacts with pre-mRNA-processing-splicing factor 8.
Nucleic Acids Res., 50, 2022
5H2F
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BU of 5h2f by Molmil
Crystal structure of the PsbM-deletion mutant of photosystem II
分子名称: (3R)-beta,beta-caroten-3-ol, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ...
著者Uto, S, Kawakami, K, Umena, Y, Iwai, M, Ikeuchi, M, Shen, J.R, Kamiya, N.
登録日2016-10-15
公開日2017-03-22
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Mutual relationships between structural and functional changes in a PsbM-deletion mutant of photosystem II.
Faraday Discuss., 198, 2017
4X1D
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BU of 4x1d by Molmil
Ytterbium-bound human serum transferrin
分子名称: GLYCEROL, MALONATE ION, Serotransferrin, ...
著者Wang, M, Zhang, H, Sun, H.
登録日2014-11-24
公開日2015-04-08
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献"Anion clamp" allows flexible protein to impose coordination geometry on metal ions
Chem.Commun.(Camb.), 51, 2015
4X6C
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BU of 4x6c by Molmil
CD1a ternary complex with lysophosphatidylcholine and BK6 TCR
分子名称: (4R,7R,18Z)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
著者Birkinshaw, R.W, Rossjohn, J.
登録日2014-12-08
公開日2015-01-28
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献alpha beta T cell antigen receptor recognition of CD1a presenting self lipid ligands.
Nat.Immunol., 16, 2015
5XZ2
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BU of 5xz2 by Molmil
Crystal structure of adenylate kinase
分子名称: Adenylate kinase isoenzyme 1, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, SULFATE ION
著者Moon, S, Bae, E, Kim, J.
登録日2017-07-11
公開日2018-07-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural analyses of adenylate kinases from Antarctic and tropical fishes for understanding cold adaptation of enzymes
Sci Rep, 7, 2017
4X60
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BU of 4x60 by Molmil
Crystal structure of PRMT5:MEP50 with EPZ015666 and sinefungin
分子名称: GLYCEROL, Methylosome protein 50, N-[(2S)-3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl]-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide, ...
著者Boriack-Sjodin, P.A.
登録日2014-12-06
公開日2015-04-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models.
Nat.Chem.Biol., 11, 2015
4X61
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BU of 4x61 by Molmil
Crystal structure of PRMT5:MEP50 with EPZ015666 and SAM
分子名称: GLYCEROL, Methylosome protein 50, N-[(2S)-3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl]-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide, ...
著者Boriack-Sjodin, P.A.
登録日2014-12-06
公開日2015-04-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models.
Nat.Chem.Biol., 11, 2015
6LQG
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BU of 6lqg by Molmil
Human gamma-secretase in complex with small molecule Avagacestat
分子名称: (2R)-2-[(4-chlorophenyl)sulfonyl-[[2-fluoranyl-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-tris(fluoranyl)pentanamide, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yang, G, Zhou, R, Guo, X, Lei, J, Shi, Y.
登録日2020-01-13
公開日2021-01-27
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of gamma-secretase inhibition and modulation by small molecule drugs.
Cell, 184, 2021
4WZS
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BU of 4wzs by Molmil
Crystal structure of the Mot1 N-terminal domain in complex with TBP and NC2 bound to a promoter DNA fragment
分子名称: DNA (5'-D(P*CP*CP*AP*CP*CP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*CP*CP*T)-3'), DNA (5'-D(P*GP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*GP*GP*TP*GP*G)-3'), ECU04_1440 protein, ...
著者Butryn, A, Hopfner, K.-P.
登録日2014-11-20
公開日2015-08-26
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.78 Å)
主引用文献Structural basis for recognition and remodeling of the TBP:DNA:NC2 complex by Mot1.
Elife, 4, 2015
6PFY
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BU of 6pfy by Molmil
Membrane Protein Megahertz Crystallography at the European XFEL, Photosystem I at synchrotron to 2.9 A
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ...
著者Fromme, R.
登録日2019-06-23
公開日2019-11-20
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Membrane protein megahertz crystallography at the European XFEL.
Nat Commun, 10, 2019
4WXF
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BU of 4wxf by Molmil
Crystal structure of L-Serine Hydroxymethyltransferase in complex with glycine
分子名称: GLYCEROL, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], Serine hydroxymethyltransferase
著者Hernandez, K, Zelen, I, Petrillo, G, Uson, I, Wadtke, C, Bujons, J, Joglar, J, Parella, T, Clapes, P.
登録日2014-11-13
公開日2015-02-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Engineered L-Serine Hydroxymethyltransferase from Streptococcus thermophilus for the Synthesis of alpha , alpha-Dialkyl-alpha-Amino Acids.
Angew.Chem.Int.Ed.Engl., 54, 2015
5GXG
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BU of 5gxg by Molmil
High-resolution crystal structure of the electron transfer complex of cytochrome p450cam with putidaredoxin
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Camphor 5-monooxygenase, FE2/S2 (INORGANIC) CLUSTER, ...
著者Kikui, Y, Hiruma, Y, Ubbink, M, Nojiri, M.
登録日2016-09-17
公開日2017-01-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Identification of productive and futile encounters in an electron transfer protein complex
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4X6D
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BU of 4x6d by Molmil
CD1a ternary complex with endogenous lipids and BK6 TCR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, OLEIC ACID, ...
著者Birkinshaw, R.W, Rossjohn, J.
登録日2014-12-08
公開日2015-01-28
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献alpha beta T cell antigen receptor recognition of CD1a presenting self lipid ligands.
Nat.Immunol., 16, 2015
6QXZ
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BU of 6qxz by Molmil
Solution structure of the ASHH2 CW domain with the N-terminal histone H3 tail mimicking peptide monomethylated on lysine 4
分子名称: ALA-ARG-THR-MLZ-GLN-THR-ALA-ARG-TYR, Histone-lysine N-methyltransferase ASHH2, ZINC ION
著者Dobrovolska, O, Madeleine, N, Teigen, K, Halskau, O, Bril'kov, M.
登録日2019-03-08
公開日2019-12-04
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Arabidopsis (ASHH2) CW domain binds monomethylated K4 of the histone H3 tail through conformational selection.
Febs J., 287, 2020
4Y2D
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BU of 4y2d by Molmil
Crystal structure of the mCD1d/7DW8-5/iNKTCR ternary complex
分子名称: 11-(4-fluorophenyl)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]undecanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zajonc, D.M, Yu, E.D.
登録日2015-02-09
公開日2015-05-27
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural modifications of alphaGalCer in both lipid and carbohydrate moiety influence activation of murine and human iNKT cells
To Be Published
4XCS
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BU of 4xcs by Molmil
Human peroxiredoxin-1 C83S mutant
分子名称: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, GLYCEROL, Peroxiredoxin-1
著者Cho, K.J, Lee, J.-H, Khan, T.G, Park, Y, Cho, A, Chang, T.-S, Kim, K.H.
登録日2014-12-18
公開日2016-01-13
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of Dimeric Human Peroxiredoxin-1 C83S Mutant
Bull.Korean Chem.Soc., 36, 2015
4XJC
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BU of 4xjc by Molmil
dCTP deaminase-dUTPase from Bacillus halodurans
分子名称: DI(HYDROXYETHYL)ETHER, Deoxycytidine triphosphate deaminase, MAGNESIUM ION, ...
著者Oehlenschlaeger, C, Loevgreen, M, Willemoes, M, Harris, P.
登録日2015-01-08
公開日2015-03-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Bacillus halodurans Strain C125 Encodes and Synthesizes Enzymes from Both Known Pathways To Form dUMP Directly from Cytosine Deoxyribonucleotides.
Appl.Environ.Microbiol., 81, 2015
5HL7
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BU of 5hl7 by Molmil
The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with lefamulin
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 23S ribosomal RNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Eyal, Z, Matzov, D, Krupkin, M, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A.
登録日2016-01-14
公開日2016-12-21
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (3.55 Å)
主引用文献A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism.
Sci Rep, 6, 2016
7QJ9
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BU of 7qj9 by Molmil
Structure of recombinant human gamma-Tubulin Ring Complex 10-spoked assembly intermediate (spokes 3-12, homogeneous dataset)
分子名称: Gamma-tubulin complex component 2, Gamma-tubulin complex component 3, Gamma-tubulin complex component 4, ...
著者Zupa, E, Pfeffer, S.
登録日2021-12-16
公開日2022-01-26
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (8.1 Å)
主引用文献Modular assembly of the principal microtubule nucleator gamma-TuRC.
Nat Commun, 13, 2022
7QJ6
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BU of 7qj6 by Molmil
Structure of recombinant human gamma-Tubulin Ring Complex 10-spoked assembly intermediate (spokes 3-12, substoichiometric spokes 13-14)
分子名称: Gamma-tubulin complex component 2, Gamma-tubulin complex component 3, Gamma-tubulin complex component 4, ...
著者Zupa, E, Pfeffer, S.
登録日2021-12-16
公開日2022-01-26
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (7.8 Å)
主引用文献Modular assembly of the principal microtubule nucleator gamma-TuRC.
Nat Commun, 13, 2022
6PGK
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BU of 6pgk by Molmil
Membrane Protein Megahertz Crystallography at the European XFEL, Photosystem I XFEL at 2.9 A
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ...
著者Fromme, R, Gisriel, C, Fromme, P.
登録日2019-06-24
公開日2019-11-27
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Membrane protein megahertz crystallography at the European XFEL.
Nat Commun, 10, 2019
5HKV
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BU of 5hkv by Molmil
The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with lincomycin
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 23s ribosomal RNA, 50S ribosomal protein L13, ...
著者Yonath, A, Matzov, D, Eyal, Z, Ben Hamou, R, Zimmerman, E, Rozenberg, H, Bashan, A, Fridman, M.
登録日2016-01-14
公開日2017-05-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.66 Å)
主引用文献Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus.
Nucleic Acids Res., 45, 2017
7M3X
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BU of 7m3x by Molmil
Crystal Structure of the Apo Form of Human RBBP7
分子名称: Histone-binding protein RBBP7, UNKNOWN ATOM OR ION
著者Righetto, G.L, Dong, A, Li, Y, Hutchinson, A, Seitova, A, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC)
登録日2021-03-19
公開日2021-05-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Crystal Structure of the Apo Form of Human RBBP7
To Be Published

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件を2025-07-09に公開中

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