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6UDM
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BU of 6udm by Molmil
Structure of Human Cytochrome P450 1A1 with Duocarmycin Prodrug (S) ICT-2726
分子名称: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Cytochrome P450 1A1, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Bart, A.G, Scott, E.E.
登録日2019-09-19
公開日2020-09-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.075 Å)
主引用文献Cytochrome P450 binding and bioactivation of tumor-targeted duocarmycin agents
Drug Metab.Dispos., 2021
1AY0
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BU of 1ay0 by Molmil
IDENTIFICATION OF CATALYTICALLY IMPORTANT RESIDUES IN YEAST TRANSKETOLASE
分子名称: CALCIUM ION, THIAMINE DIPHOSPHATE, TRANSKETOLASE
著者Wikner, C, Nilsson, U, Meshalkina, L, Udekwu, C, Lindqvist, Y, Schneider, G.
登録日1997-11-13
公開日1998-05-13
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Identification of catalytically important residues in yeast transketolase.
Biochemistry, 36, 1997
1AL9
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BU of 1al9 by Molmil
NMR STUDY OF DNA (5'-D(*AP*CP*GP*TP*AP*CP*GP*T)-3') SELF-COMPLEMENTARY DUPLEX COMPLEXED WITH A BIS-DAUNORUBICIN, MINIMIZED AVERAGE STRUCTURE
分子名称: 4-METHYLBENZYL-N-BIS[DAUNOMYCIN], DNA (5'-D(*AP*CP*GP*TP*AP*CP*GP*T)-3')
著者Robinson, H, Wang, A.H.-J.
登録日1997-06-12
公開日1997-09-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Binding of two novel bisdaunorubicins to DNA studied by NMR spectroscopy.
Biochemistry, 36, 1997
6GP2
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BU of 6gp2 by Molmil
Ribonucleotide Reductase class Ie R2 from Mesoplasma florum, DOPA-active form
分子名称: CALCIUM ION, Ribonucleoside-diphosphate reductase beta chain
著者Srinivas, V, Lebrette, H, Lundin, D, Kutin, Y, Sahlin, M, Lerche, M, Enrich, J, Branca, R.M.M, Cox, N, Sjoberg, B.M, Hogbom, M.
登録日2018-06-05
公開日2018-08-22
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Metal-free ribonucleotide reduction powered by a DOPA radical in Mycoplasma pathogens.
Nature, 563, 2018
7YLZ
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BU of 7ylz by Molmil
Unliganded form of hydroxyamidotransferase TsnB9
分子名称: SULFATE ION, hydroxyamidotransferase
著者Nagata, R, Nishiyama, M, Kuzuyama, T.
登録日2022-07-27
公開日2023-05-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Substrate Recognition Mechanism of a Trichostatin A-Forming Hydroxyamidotransferase.
Biochemistry, 62, 2023
7YFS
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BU of 7yfs by Molmil
The NMR structure of noursin, a tricyclic ribosomal peptide containing a histidine-to-butyrine crosslink
分子名称: noursin
著者Yao, H, Li, Y, Zhang, T, Gao, J, Wang, H.
登録日2022-07-09
公開日2023-05-31
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Discovery and biosynthesis of tricyclic copper-binding ribosomal peptides containing histidine-to-butyrine crosslinks.
Nat Commun, 14, 2023
3OEH
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BU of 3oeh by Molmil
Structure of four mutant forms of yeast F1 ATPase: beta-V279F
分子名称: ATP synthase subunit alpha, ATP synthase subunit beta, ATP synthase subunit delta, ...
著者Arsenieva, D, Symersky, J, Wang, Y, Pagadala, V, Mueller, D.M.
登録日2010-08-12
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of mutant forms of the yeast f1 ATPase reveal two modes of uncoupling.
J.Biol.Chem., 285, 2010
1JZY
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BU of 1jzy by Molmil
Structural Basis for the Interaction of Antibiotics with the Peptidyl Transferase Center in Eubacteria
分子名称: 23S rRNA, ERYTHROMYCIN A, MAGNESIUM ION, ...
著者Schluenzen, F, Zarivach, R, Harms, J, Bashan, A, Tocilj, A, Albrecht, R, Yonath, A, Franceschi, F.
登録日2001-09-17
公開日2001-10-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria.
Nature, 413, 2001
3OE7
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BU of 3oe7 by Molmil
Structure of four mutant forms of yeast f1 ATPase: gamma-I270T
分子名称: ATP synthase subunit alpha, ATP synthase subunit beta, ATP synthase subunit delta, ...
著者Arsenieva, D, Symersky, J, Wang, Y, Pagadala, V, Mueller, D.M.
登録日2010-08-12
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Crystal structures of mutant forms of the yeast f1 ATPase reveal two modes of uncoupling.
J.Biol.Chem., 285, 2010
1FH7
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CRYSTAL STRUCTURE OF THE XYLANASE CEX WITH XYLOBIOSE-DERIVED INHIBITOR DEOXYNOJIRIMYCIN
分子名称: BETA-1,4-XYLANASE, PIPERIDINE-3,4,5-TRIOL, beta-D-xylopyranose
著者Notenboom, V, Williams, S.J, Hoos, R, Withers, S.G, Rose, D.R.
登録日2000-07-31
公開日2000-08-23
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Detailed structural analysis of glycosidase/inhibitor interactions: complexes of Cex from Cellulomonas fimi with xylobiose-derived aza-sugars.
Biochemistry, 39, 2000
3OEE
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BU of 3oee by Molmil
Structure of four mutant forms of yeast F1 ATPase: alpha-F405S
分子名称: ATP synthase subunit alpha, ATP synthase subunit beta, ATP synthase subunit delta, ...
著者Arsenieva, D, Symersky, J, Wang, Y, Pagadala, V, Mueller, D.M.
登録日2010-08-12
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Structure of four mutant forms of yeast F1 ATPase: alpha-F405S
To be Published
3OFN
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BU of 3ofn by Molmil
Structure of four mutant forms of yeast F1 ATPase: alpha-N67I
分子名称: ATP synthase subunit alpha, ATP synthase subunit beta, ATP synthase subunit delta, ...
著者Arsenieva, D, Symersky, J, Wang, Y, Pagadala, V, Mueller, D.M.
登録日2010-08-15
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structures of mutant forms of the yeast f1 ATPase reveal two modes of uncoupling.
J.Biol.Chem., 285, 2010
6HWE
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BU of 6hwe by Molmil
Yeast 20S proteasome beta2-G45A mutant in complex with carfilzomib
分子名称: (2~{S})-~{N}-[(2~{S})-1-[[(3~{R},4~{S})-2,6-dimethyl-2,3-bis(oxidanyl)heptan-4-yl]amino]-1-oxidanylidene-3-phenyl-propan-2-yl]-4-methyl-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)-4-phenyl-butanoyl]amino]pentanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ...
著者Huber, E.M, Groll, M.
登録日2018-10-11
公開日2019-01-30
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
4INQ
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BU of 4inq by Molmil
Crystal structure of Osh3 ORD in complex with PI(4)P from Saccharomyces cerevisiae
分子名称: (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, Oxysterol-binding protein homolog 3
著者Tong, J, Im, Y.J.
登録日2013-01-05
公開日2013-07-31
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of osh3 reveals a conserved mode of phosphoinositide binding in oxysterol-binding proteins
Structure, 21, 2013
7UUM
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BU of 7uum by Molmil
Crystal structure of aminoglycoside resistance enzyme ApmA, complex with paromomycin and coenzyme A
分子名称: Aminocyclitol acetyltransferase ApmA, COENZYME A, GLYCEROL, ...
著者Stogios, P.J, Evdokimova, E, Osipiuk, J, Di Leo, R, Bordeleau, E, Wright, G.D, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
登録日2022-04-28
公開日2022-11-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Mechanistic plasticity in ApmA enables aminoglycoside promiscuity for resistance.
Nat.Chem.Biol., 20, 2024
6GP3
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BU of 6gp3 by Molmil
Ribonucleotide Reductase class Ie R2 from Mesoplasma florum, inactive form
分子名称: CALCIUM ION, Ribonucleoside-diphosphate reductase beta chain
著者Srinivas, V, Lebrette, H, Lundin, D, Kutin, Y, Sahlin, M, Lerche, M, Enrich, J, Branca, R.M.M, Cox, N, Sjoberg, B.M, Hogbom, M.
登録日2018-06-05
公開日2018-08-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Metal-free ribonucleotide reduction powered by a DOPA radical in Mycoplasma pathogens.
Nature, 563, 2018
1OIN
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BU of 1oin by Molmil
Family 1 b-glucosidase from Thermotoga maritima
分子名称: 2-deoxy-2-fluoro-alpha-D-glucopyranose, BETA-GLUCOSIDASE A
著者Gloster, T, Zechel, D.L, Boraston, A.B, Boraston, C.M, Macdonald, J.M, Tilbrook, D.M, Stick, R.V, Davies, G.J.
登録日2003-06-19
公開日2003-11-25
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Iminosugar Glycosidase Inhibitors: Structural and Thermodynamic Dissection of the Binding of Isofagomine and 1-Deoxynojirimycin to Beta-Glucosidases
J.Am.Chem.Soc., 125, 2003
6HV9
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BU of 6hv9 by Molmil
S. cerevisiae CMG-Pol epsilon-DNA
分子名称: Cell division control protein 45, DNA (5'-D(*GP*CP*AP*GP*CP*CP*AP*CP*GP*CP*TP*GP*GP*CP*CP*GP*TP*TP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*AP*AP*CP*GP*GP*CP*CP*AP*GP*CP*GP*TP*GP*GP*CP*TP*GP*C)-3'), ...
著者Abid Ali, F, Purkiss, A.G, Cheung, A, Costa, A.
登録日2018-10-10
公開日2018-12-12
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (4.98 Å)
主引用文献Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome.
Nat Commun, 9, 2018
1OA4
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BU of 1oa4 by Molmil
Comparison of Family 12 Glycoside Hydrolases and Recruited Substitutions Important for Thermal Stability
分子名称: ENDO-BETA-1,4-GLUCANASE
著者Sandgren, M, Gualfetti, P.J, Shaw, A, Gross, L.S, Saldajeno, M, Day, A.G, Jones, T.A, Mitchinson, C.
登録日2002-12-28
公開日2003-03-27
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Comparison of Family 12 Glycoside Hydrolases and Recruited Substitutions Important for Thermal Stability
Protein Sci., 12, 2003
1Q82
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BU of 1q82 by Molmil
Crystal Structure of CC-Puromycin bound to the A-site of the 50S ribosomal subunit
分子名称: 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ...
著者Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A.
登録日2003-08-20
公開日2003-10-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Structural Insights Into Peptide Bond Formation
Proc.Natl.Acad.Sci.USA, 99, 2002
1JZZ
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BU of 1jzz by Molmil
Structural Basis for the Interaction of Antibiotics with the Peptidyl Transferase Center in Eubacteria
分子名称: 23S rRNA, MAGNESIUM ION, ROXITHROMYCIN, ...
著者Schluenzen, F, Zarivach, R, Harms, J, Bashan, A, Tocilj, A, Albrecht, R, Yonath, A, Franceschi, F.
登録日2001-09-17
公開日2001-10-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria.
Nature, 413, 2001
1Q7Y
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BU of 1q7y by Molmil
Crystal Structure of CCdAP-Puromycin bound at the Peptidyl transferase center of the 50S ribosomal subunit
分子名称: 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ...
著者Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A.
登録日2003-08-20
公開日2003-10-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Insights Into Peptide Bond Formation
Proc.Natl.Acad.Sci.USA, 99, 2002
3OSP
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BU of 3osp by Molmil
Structure of rev1
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*(DOC))-3', 5'-D(*TP*AP*AP*(3DR)P*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*AP*T)-3', ...
著者Nair, D.T, Aggarwal, A.K.
登録日2010-09-09
公開日2011-04-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献DNA synthesis across an abasic lesion by yeast REV1 DNA polymerase.
J.Mol.Biol., 406, 2011
1Q81
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Crystal Structure of minihelix with 3' puromycin bound to A-site of the 50S ribosomal subunit.
分子名称: 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ...
著者Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A.
登録日2003-08-20
公開日2003-10-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural Insights into Peptide Bond Formation
Proc.Natl.Acad.Sci.USA, 99, 2002
2XJR
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BU of 2xjr by Molmil
X-ray structure of the N-terminal domain of the flocculin Flo5 from Saccharomyces cerevisiae in complex with calcium and Man5(D2-D3)
分子名称: CALCIUM ION, CHLORIDE ION, FLOCCULATION PROTEIN FLO5, ...
著者Veelders, M, Brueckner, S, Ott, D, Unverzagt, C, Moesch, H.-U, Essen, L.-O.
登録日2010-07-06
公開日2010-12-15
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structural Basis of Flocculin-Mediated Social Behavior in Yeast
Proc.Natl.Acad.Sci.USA, 107, 2010

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