8TSS
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![BU of 8tss by Molmil](/molmil-images/mine/8tss) | Open, inward-facing MsbA structure (OIF3) | 分子名称: | ATP-binding transport protein MsbA | 著者 | Yang, B, Zhang, T, Lyu, J, Laganowsky, A.D, Zhao, M. | 登録日 | 2023-08-11 | 公開日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Native mass spectrometry captures snapshots of the MsbA transport cycle To Be Published
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8TSQ
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![BU of 8tsq by Molmil](/molmil-images/mine/8tsq) | Open, inward-facing MsbA structure (OIF2) | 分子名称: | ATP-binding transport protein MsbA | 著者 | Yang, B, Zhang, T, Lyu, J, Laganowsky, A.D, Zhao, M. | 登録日 | 2023-08-11 | 公開日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Native mass spectrometry captures snapshots of the MsbA transport cycle To Be Published
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8T4H
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![BU of 8t4h by Molmil](/molmil-images/mine/8t4h) | |
8T4E
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![BU of 8t4e by Molmil](/molmil-images/mine/8t4e) | |
8TSO
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![BU of 8tso by Molmil](/molmil-images/mine/8tso) | KDL bound, nucleotide-free MsbA in open, outward-facing conformation | 分子名称: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]-5-oxidanyl-oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, ATP-binding transport protein MsbA, PENTAETHYLENE GLYCOL MONODECYL ETHER | 著者 | Yang, B, Zhang, T, Lyu, J, Laganowsky, A.D, Zhao, M. | 登録日 | 2023-08-11 | 公開日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | 主引用文献 | Native mass spectrometry captures snapshots of the MsbA transport cycle To Be Published
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8GLS
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![BU of 8gls by Molmil](/molmil-images/mine/8gls) | |
8WI2
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![BU of 8wi2 by Molmil](/molmil-images/mine/8wi2) | RD-hMRP5-inward open | 分子名称: | ATP-binding cassette sub-family C member 5, CYS-GLN-ASP-ALA-LEU-GLU-THR-ALA-ALA-ARG-ALA-GLU-GLY-LEU-SER-LEU-ASP-ALA-SER | 著者 | Liu, Z.M, Huang, Y. | 登録日 | 2023-09-24 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (4.06 Å) | 主引用文献 | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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8WI3
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![BU of 8wi3 by Molmil](/molmil-images/mine/8wi3) | ND-hMRP5-inward open | 分子名称: | ATP-binding cassette sub-family C member 5 | 著者 | Liu, Z.M, Huang, Y. | 登録日 | 2023-09-24 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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8WI0
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![BU of 8wi0 by Molmil](/molmil-images/mine/8wi0) | wt-hMRP5 inward-open | 分子名称: | ATP-binding cassette sub-family C member 5 | 著者 | Liu, Z.M, Huang, Y. | 登録日 | 2023-09-24 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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8WI5
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![BU of 8wi5 by Molmil](/molmil-images/mine/8wi5) | M5PI-bound hMRP5 | 分子名称: | ATP-binding cassette sub-family C member 5 | 著者 | Liu, Z.M, Huang, Y. | 登録日 | 2023-09-24 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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8WI4
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![BU of 8wi4 by Molmil](/molmil-images/mine/8wi4) | m6-hMRP5 inward open | 分子名称: | ATP-binding cassette sub-family C member 5 | 著者 | Liu, Z.M, Huang, Y. | 登録日 | 2023-09-24 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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8KCI
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![BU of 8kci by Molmil](/molmil-images/mine/8kci) | ATP-bound hMRP5 outward-open | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 5, MAGNESIUM ION | 著者 | Liu, Z.M, Huang, Y. | 登録日 | 2023-08-07 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.94 Å) | 主引用文献 | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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8XOL
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![BU of 8xol by Molmil](/molmil-images/mine/8xol) | Cryo-EM structure of human ABCC4 with ANP bound in NBD1 | 分子名称: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, MAGNESIUM ION, ... | 著者 | Zhang, P.F, Liu, Z. | 登録日 | 2024-01-01 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport. Febs Lett., 2024
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8XOM
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![BU of 8xom by Molmil](/molmil-images/mine/8xom) | Cryo-EM structure of human ABCC4 in complex with ANP-bound in NBD1 and METHOTREXATE | 分子名称: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, MAGNESIUM ION, ... | 著者 | Zhang, P.F, Liu, Z. | 登録日 | 2024-01-01 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport. Febs Lett., 2024
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8V81
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![BU of 8v81 by Molmil](/molmil-images/mine/8v81) | Phosphorylated, ATP-bound, inhibitor 172-bound E1371Q human cystic fibrosis transmembrane conductance regulator | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 4-[(Z)-{(3M)-4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Gao, X, Hwang, T. | 登録日 | 2023-12-04 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Allosteric inhibition of CFTR gating by CFTRinh-172 binding in the pore Nat Commun, 2024
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8V7Z
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![BU of 8v7z by Molmil](/molmil-images/mine/8v7z) | |
8K0X
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![BU of 8k0x by Molmil](/molmil-images/mine/8k0x) | ABCG25 Wild Type purified with DDM in the ABA-bound state | 分子名称: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, ABC transporter G family member 25 | 著者 | Sun, L, Liu, X, Ying, W, Liao, L, Wei, H. | 登録日 | 2023-07-10 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | ABCG25 Wild Type purified with DDM in the ABA-bound state To Be Published
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8K0Z
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![BU of 8k0z by Molmil](/molmil-images/mine/8k0z) | |
8K1O
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![BU of 8k1o by Molmil](/molmil-images/mine/8k1o) | mycobacterial efflux pump, AMPPNP bound state | 分子名称: | CARDIOLIPIN, MAGNESIUM ION, Multidrug efflux system ATP-binding protein Rv1218c, ... | 著者 | Wang, Y, Wu, F, Zhang, L, Rao, Z. | 登録日 | 2023-07-11 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | mycobacterial efflux pump, AMPPNP bound state To Be Published
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8K1N
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![BU of 8k1n by Molmil](/molmil-images/mine/8k1n) | mycobacterial efflux pump, substrate-bound state | 分子名称: | CARDIOLIPIN, Multidrug efflux system ATP-binding protein Rv1218c, Multidrug efflux system permease protein Rv1217c, ... | 著者 | Wang, Y, Wu, F, Zhang, L, Rao, Z. | 登録日 | 2023-07-11 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | mycobacterial efflux pump, substrate-bound state To Be Published
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8K1M
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![BU of 8k1m by Molmil](/molmil-images/mine/8k1m) | mycobacterial efflux pump, apo state | 分子名称: | (1S)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CARDIOLIPIN, Multidrug efflux system ATP-binding protein Rv1218c, ... | 著者 | Wang, Y, Wu, F, Zhang, L, Rao, Z. | 登録日 | 2023-07-11 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | mycobacterial efflux pump, apo state To Be Published
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8K1P
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![BU of 8k1p by Molmil](/molmil-images/mine/8k1p) | mycobacterial efflux pump, ADP+vanadate bound state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CARDIOLIPIN, ... | 著者 | Wang, Y, Wu, F, Zhang, L, Rao, Z. | 登録日 | 2023-07-11 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | mycobacterial efflux pump, ADP+vanadate bound state To Be Published
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8XOK
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![BU of 8xok by Molmil](/molmil-images/mine/8xok) | Cryo-EM structure of human ABCC4 | 分子名称: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, PALMITIC ACID | 著者 | Zhang, P.F, Liu, Z. | 登録日 | 2024-01-01 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | 主引用文献 | The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport. Febs Lett., 2024
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