PDB: 41454 件ウェブページステータス検索Chemie searchBIRD

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1KF9	PHAGE DISPLAY DERIVED VARIANT OF HUMAN GROWTH HORMONE COMPLEXED WITH TWO COPIES OF THE EXTRACELLULAR DOMAIN OF ITS RECEPTOR 分子名称: EXTRACELLULAR DOMAIN HUMAN GROWTH HORMONE RECEPTOR (1-238), PHAGE DISPLAY DERIVED VARIANT HUMAN GROWTH HORMONE 著者 Schiffer, C.A, Ultsch, M, Walsh, S, Somers, W, De Vos, A.M, Kossiakoff, A.A. 登録日 2001-11-19 公開日 2002-11-20 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of a Phage Display Derived Variant of Human Growth Hormone Complexed to Two Copies of the Extracellular Domain of its Receptor: Evidence for Strong Structural Coupling between Receptor Binding Sites J.Mol.Biol., 316, 2002
8IDQ	Crystal structure of reducing-end xylose-releasing exoxylanase in GH30 from Talaromyces cellulolyticus with xylose 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... 著者 Nakamichi, Y, Watanabe, M, Fujii, T, Inoue, H, Morita, T. 登録日 2023-02-14 公開日 2023-05-17 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of reducing-end xylose-releasing exoxylanase in subfamily 7 of glycoside hydrolase family 30. Proteins, 91, 2023
8IDP	Crystal structure of reducing-end xylose-releasing exoxylanase in GH30 from Talaromyces cellulolyticus 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... 著者 Nakamichi, Y, Watanabe, M, Fujii, T, Inoue, H, Morita, T. 登録日 2023-02-14 公開日 2023-05-17 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of reducing-end xylose-releasing exoxylanase in subfamily 7 of glycoside hydrolase family 30. Proteins, 91, 2023
7UOM	Endogenous dihydrolipoamide acetyltransferase (E2) core of pyruvate dehydrogenase complex from bovine kidney 分子名称: Acetyltransferase component of pyruvate dehydrogenase complex 著者 Liu, S, Xia, X, Zhen, J, Li, Z.H, Zhou, Z.H. 登録日 2022-04-13 公開日 2022-11-30 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structures and comparison of endogenous 2-oxoglutarate and pyruvate dehydrogenase complexes from bovine kidney. Cell Discov, 8, 2022
7UOL	Endogenous dihydrolipoamide succinyltransferase (E2) core of 2-oxoglutarate dehydrogenase complex from bovine kidney 分子名称: Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial 著者 Liu, S, Xia, X, Zhen, J, Li, Z.H, Zhou, Z.H. 登録日 2022-04-13 公開日 2022-11-30 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structures and comparison of endogenous 2-oxoglutarate and pyruvate dehydrogenase complexes from bovine kidney. Cell Discov, 8, 2022
6MXR	Crystal structure of the dimeric bH1-Fab variant [HC-Y33W,HC-D98M,HC-G99M] 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ... 著者 Shi, R. 登録日 2018-10-31 公開日 2019-07-31 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Binding symmetry and surface flexibility mediate antibody self-association. Mabs, 11, 2019
8FY2	E3:PROTAC:target ternary complex structure (VCB/WH244/BCL-2) 分子名称: Apoptosis regulator Bcl-2, Elongin-B, Elongin-C, ... 著者 Nayak, D, Lv, D, Yuan, Y, Zhang, P, Hu, W, Ruben, E, Lv, Z, Sung, P, Hromas, R, Zheng, G, Zhou, D, Olsen, S.K. 登録日 2023-01-25 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL. Nat Commun, 15, 2024
8FY1	E3:PROTAC:target ternary complex structure (VCB/753b/BCL-2) 分子名称: Apoptosis regulator Bcl-2, Elongin-B, Elongin-C, ... 著者 Nayak, D, Lv, D, Yuan, Y, Zhang, P, Hu, W, Lv, Z, Sung, P, Hromas, R, Zheng, G, Zhou, D, Olsen, S.K. 登録日 2023-01-25 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL. Nat Commun, 15, 2024
8FY0	E3:PROTAC:target ternary complex structure (VCB/753b/BCL-xL) 分子名称: Bcl-2-like protein 1, CACODYLIC ACID, Elongin-B, ... 著者 Olsen, S.K, Nayak, D, Lv, D, Yuan, Y, Zhang, P, Hu, W, Lv, Z, Sung, P, Hromas, R, Zheng, G, Zhou, D. 登録日 2023-01-25 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.94 Å) 主引用文献 Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL. Nat Commun, 15, 2024
7WLC	SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv282 分子名称: Heavy chain of XGv282, Light chain of XGv282, Spike protein S1 著者 Wang, X, Wang, L. 登録日 2022-01-13 公開日 2022-04-13 最終更新日 2022-05-04 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants. Nature, 603, 2022
6MPN	Racemic M2-TM I42E crystallized from racemic detergent 分子名称: Matrix protein 2, octyl beta-D-glucopyranoside 著者 Kreitler, D.F, Yao, Z, Mortenson, D.E, Forest, K.T, Gellman, S.H. 登録日 2018-10-07 公開日 2019-01-30 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation. J. Am. Chem. Soc., 141, 2019
6B29	Crystal structure of the second SH3 domain of STAC3 (309-364) 分子名称: SH3 and cysteine-rich domain-containing protein 3 著者 Wong King Yuen, S.M, Van Petegem, F. 登録日 2017-09-19 公開日 2017-10-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structural insights into binding of STAC proteins to voltage-gated calcium channels. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7WED	SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv347 分子名称: Spike protein S1, The heavy chain of Fab XGv347, The light chain of Fab XGv347 著者 Wang, X, Wang, L. 登録日 2021-12-23 公開日 2022-04-13 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants. Nature, 603, 2022
6MPM	Racemic M2-TM I42A crystallized from racemic detergent 分子名称: Matrix protein 2, octyl beta-D-glucopyranoside 著者 Kreitler, D.F, Yao, Z, Mortenson, D.E, Forest, K.T, Gellman, S.H. 登録日 2018-10-07 公開日 2019-01-30 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation. J. Am. Chem. Soc., 141, 2019
6XTX	CryoEM structure of human CMG bound to ATPgammaS and DNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45 homolog, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ... 著者 Rzechorzek, N.J, Pellegrini, L. 登録日 2020-01-16 公開日 2020-05-27 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.29 Å) 主引用文献 CryoEM structures of human CMG-ATP gamma S-DNA and CMG-AND-1 complexes. Nucleic Acids Res., 48, 2020
6XW5	Crystal structure of murine norovirus P domain in complex with Nanobody NB-5820 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Capsid protein, ... 著者 Kilic, T, Sabin, C, Hansman, G. 登録日 2020-01-23 公開日 2020-04-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Nanobody-Mediated Neutralization Reveals an Achilles Heel for Norovirus. J.Virol., 94, 2020
5M3X	Crystal structure of human angiotensin I-deleted angiotensinogen 分子名称: Angiotensinogen 著者 Yan, Y, Read, R.J. 登録日 2016-10-17 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Structural basis for the specificity of renin-mediated angiotensinogen cleavage. J. Biol. Chem., 294, 2019
7WEA	SARS-CoV-2 Omicron variant spike protein in complex with two XGv347 binding to one close state RBD and one open state RBD 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... 著者 Wang, X, Wang, L. 登録日 2021-12-23 公開日 2022-05-04 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants. Nature, 603, 2022
7WEC	SARS-CoV-2 Omicron variant spike protein with three XGv347 Fabs binding to three closed state RBDs 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... 著者 Wang, X, Wang, L. 登録日 2021-12-23 公開日 2022-05-04 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants. Nature, 603, 2022
3N0P	A mutant human Prolactin receptor antagonist H30A in complex with the extracellular domain of the human prolactin receptor 分子名称: CHLORIDE ION, Prolactin, Prolactin receptor, ... 著者 Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E. 登録日 2010-05-14 公開日 2010-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation. J.Biol.Chem., 285, 2010
7WE8	SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv265 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 265, ... 著者 Wang, X, Wang, L. 登録日 2021-12-23 公開日 2022-05-04 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants. Nature, 603, 2022
6SHX	DNA mismatch repair proteins MLH1 and MLH3 分子名称: DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION 著者 Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B. 登録日 2019-08-08 公開日 2021-05-19 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation. Proc.Natl.Acad.Sci.USA, 118, 2021
6SNS	DNA mismatch repair proteins MLH1 and MLH3 分子名称: DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION 著者 Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B. 登録日 2019-08-27 公開日 2021-05-19 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation. Proc.Natl.Acad.Sci.USA, 118, 2021
6SNV	DNA mismatch repair proteins MLH1 and MLH3 分子名称: DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION 著者 Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B. 登録日 2019-08-27 公開日 2021-05-19 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation. Proc.Natl.Acad.Sci.USA, 118, 2021
7WE7	SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv282 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 282, ... 著者 Wang, X, Wang, L. 登録日 2021-12-23 公開日 2022-05-04 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants. Nature, 603, 2022

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