PDB: 8861 件ウェブページステータス検索Chemie searchBIRD

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1VSH	ASV INTEGRASE CORE DOMAIN WITH ZN(II) COFACTORS 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, INTEGRASE, ZINC ION 著者 Bujacz, G, Alexandratos, J, Wlodawer, A. 登録日 1997-03-04 公開日 1997-05-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Binding of different divalent cations to the active site of avian sarcoma virus integrase and their effects on enzymatic activity. J.Biol.Chem., 272, 1997
1VSJ	ASV INTEGRASE CORE DOMAIN WITH CD(II) COFACTORS 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CADMIUM ION, INTEGRASE 著者 Bujacz, G, Alexandratos, J, Wlodawer, A. 登録日 1997-03-04 公開日 1997-05-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Binding of different divalent cations to the active site of avian sarcoma virus integrase and their effects on enzymatic activity. J.Biol.Chem., 272, 1997
1VSI	ASV INTEGRASE CORE DOMAIN WITH CA(II) COFACTOR 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, INTEGRASE 著者 Bujacz, G, Alexandratos, J, Wlodawer, A. 登録日 1997-03-04 公開日 1997-05-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Binding of different divalent cations to the active site of avian sarcoma virus integrase and their effects on enzymatic activity. J.Biol.Chem., 272, 1997
8SF7	48-nm doublet microtubule from Tetrahymena thermophila strain MEC17 分子名称: CFAM166A, CFAM166B, CFAM166C, ... 著者 Black, C.S, Kubo, S, Yang, S.K, Bui, K.H. 登録日 2023-04-10 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Effect of alpha-tubulin acetylation on the doublet microtubule structure. Elife, 12, 2024
8FS4	Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 2 (open 9-1-1 ring and flexibly bound chamber DNA) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ... 著者 Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. 登録日 2023-01-09 公開日 2023-06-14 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology. Biorxiv, 2023
3ST1	Crystal structure of Necrosis and Ethylene inducing Protein 2 from the causal agent of cocoa's Witches Broom disease 分子名称: Necrosis-and ethylene-inducing protein, SODIUM ION, ZINC ION 著者 Oliveira, J.F, Zaparoli, G, Barsottini, M.R.O, Ambrosio, A.L.B, Pereira, G.A.G, Dias, S.M.G. 登録日 2011-07-08 公開日 2011-11-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Crystal Structure of Necrosis- and Ethylene-Inducing Protein 2 from the Causal Agent of Cacao's Witches' Broom Disease Reveals Key Elements for Its Activity. Biochemistry, 50, 2011
1DXP	Inhibition of the Hepatitis C Virus NS3/4A Protease. The Crystal Structures of Two Protease-Inhibitor Complexes (apo structure) 分子名称: GLYCEROL, NONSTRUCTURAL PROTEIN NS4A (P4), PROTEASE/HELICASE NS3 (P70), ... 著者 Di Marco, S, Rizzi, M, Volpari, C, Walsh, M, Narjes, F, Colarusso, S, De Francesco, R, Matassa, V.G, Sollazzo, M. 登録日 2000-01-13 公開日 2001-01-12 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Inhibition of the Hepatitis C Virus Ns3/4A Protease the Crystal Structures of Two Protease-Inhibitor Complexes J.Biol.Chem., 275, 2000
8FS3	Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 1 (open 9-1-1 and shoulder bound DNA only) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ... 著者 Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. 登録日 2023-01-09 公開日 2023-06-14 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.93 Å) 主引用文献 Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology. Biorxiv, 2023
1CYN	CYCLOPHILIN B COMPLEXED WITH [D-(CHOLINYLESTER)SER8]-CYCLOSPORIN 分子名称: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE B 著者 Mikol, V, Kallen, J, Walkinshaw, M.D. 登録日 1995-05-22 公開日 1996-01-29 最終更新日 2018-09-12 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 X-Ray Structure of a Cyclophilin B/Cyclosporin Complex: Comparison with Cyclophilin a and Delineation of its Calcineurin-Binding Domain. Proc.Natl.Acad.Sci.USA, 91, 1994
1VOK	ARABIDOPSIS THALIANA TBP (DIMER) 分子名称: SULFATE ION, TATA-BOX-BINDING PROTEIN 著者 Nikolov, D.B, Burley, S.K. 登録日 1996-04-29 公開日 1996-11-08 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 2.1 A resolution refined structure of a TATA box-binding protein (TBP). Nat.Struct.Biol., 1, 1994
4BFP	Crystal structure of human tankyrase 2 in complex with WIKI4 分子名称: 2-[3-[[4-(4-methoxyphenyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]propyl]benzo[de]isoquinoline-1,3-dione, SULFATE ION, TANKYRASE-2, ... 著者 Haikarainen, T, Narwal, M, Lehtio, L. 登録日 2013-03-21 公開日 2013-06-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Basis and Selectivity of Tankyrase Inhibition by a Wnt Signaling Inhibitor Wiki4 Plos One, 8, 2013
3MHK	Human tankyrase 2 - catalytic PARP domain in complex with 2-(2-pyridyl)-7,8-dihydro-5h-thiino[4,3-d]pyrimidin-4-ol 分子名称: 2-pyridin-2-yl-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-4-ol, GLYCEROL, Tankyrase-2, ... 著者 Karlberg, T, Schutz, P, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Kotenyova, T, Markova, N, Moche, M, Nordlund, P, Nyman, T, Persson, C, Siponen, M.I, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC) 登録日 2010-04-08 公開日 2010-05-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors Nat.Biotechnol., 30, 2012
3MHJ	Human tankyrase 2 - catalytic PARP domain in complex with 1-methyl-3-(trifluoromethyl)-5h-benzo[c][1,8]naphtyridine-6-one 分子名称: 1-methyl-3-(trifluoromethyl)benzo[c][1,8]naphthyridin-6(5H)-one, SULFATE ION, Tankyrase-2, ... 著者 Karlberg, T, Schutz, P, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Kotenyova, T, Markova, N, Moche, M, Nordlund, P, Nyman, T, Persson, C, Siponen, M.I, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC) 登録日 2010-04-08 公開日 2010-05-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors Nat.Biotechnol., 30, 2012
4J1Z	Tankyrase 2 in complex with 4-chloro-1,2-dihydrophatalzin-one 分子名称: 4-chlorophthalazin-1(2H)-one, SULFATE ION, Tankyrase-2, ... 著者 Jansson, A.E. 登録日 2013-02-03 公開日 2013-07-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Fragment-based ligand design of novel potent inhibitors of tankyrases. J.Med.Chem., 56, 2013
1CKI	RECOMBINANT CASEIN KINASE I DELTA TRUNCATION MUTANT CONTAINING RESIDUES 1-317 分子名称: CASEIN KINASE I DELTA 著者 Longenecker, K.L, Roach, P.J, Hurley, T.D. 登録日 1995-08-25 公開日 1995-12-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Three-dimensional structure of mammalian casein kinase I: molecular basis for phosphate recognition. J.Mol.Biol., 257, 1996
2JX3	NMR solution structure of the N-terminal domain of DEK 分子名称: Protein DEK 著者 Matsuo, H, Devany, M. 登録日 2007-11-02 公開日 2008-02-12 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution NMR structure of the N-terminal domain of the human DEK protein Protein Sci., 17, 2008
7KRD	Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 4-(3-chloro-5-cyanophenoxy)-3-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenyl sulfurofluoridate (JLJ702) 分子名称: 4-(3-chloro-5-cyanophenoxy)-3-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenyl sulfurofluoridate, HIV-1 REVERSE TRANSCRIPTASE, P51 SUBUNIT, ... 著者 Bertoletti, N, Ippolito, J.A, Jorgensen, W.L, Anderson, K.S. 登録日 2020-11-19 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Covalent Inhibition of Wild-Type HIV-1 Reverse Transcriptase Using a Fluorosulfate Warhead. Acs Med.Chem.Lett., 12, 2021
8JND	The cryo-EM structure of the nonameric RAD51 ring bound to the nucleosome with the linker DNA binding 分子名称: DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ... 著者 Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H. 登録日 2023-06-06 公開日 2024-03-27 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.66 Å) 主引用文献 Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site. Nature, 628, 2024
8JNE	The cryo-EM structure of the decameric RAD51 ring bound to the nucleosome without the linker DNA binding 分子名称: DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ... 著者 Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H. 登録日 2023-06-06 公開日 2024-03-27 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (4.68 Å) 主引用文献 Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site. Nature, 628, 2024
8JNF	The cryo-EM structure of the RAD51 filament bound to the nucleosome 分子名称: DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ... 著者 Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H. 登録日 2023-06-06 公開日 2024-03-27 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (6.91 Å) 主引用文献 Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site. Nature, 628, 2024
8XBU	The cryo-EM structure of the decameric RAD51 ring bound to the nucleosome with the linker DNA binding 分子名称: DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ... 著者 Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H. 登録日 2023-12-07 公開日 2024-03-27 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (4.24 Å) 主引用文献 Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site. Nature, 628, 2024
8XBT	The cryo-EM structure of the octameric RAD51 ring bound to the nucleosome with the linker DNA binding 分子名称: DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ... 著者 Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H. 登録日 2023-12-07 公開日 2024-03-27 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (4.12 Å) 主引用文献 Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site. Nature, 628, 2024
7U5Z	Crystal Structure of HIV-1 Reverse Transcriptase in Complex with JLJ353 分子名称: 2-chloro-4-({5-[(2,6-difluorophenyl)methyl]-1,3-oxazol-2-yl}amino)benzonitrile, Reverse transcriptase/ribonuclease H, p51 RT 著者 Hollander, K, Carter, Z, Jorgensen, W.L, Anderson, K.S. 登録日 2022-03-03 公開日 2023-03-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Design, synthesis, and biological testing of biphenylmethyloxazole inhibitors targeting HIV-1 reverse transcriptase. Bioorg.Med.Chem.Lett., 84, 2023
6WPH	Structure of HIV-1 Reverse Transcriptase (RT) in complex with dsDNA and (-)-FTC 分子名称: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, DNA Primer 21-mer, DNA template 27-mer, ... 著者 Bertoletti, N, Anderson, K.S. 登録日 2020-04-27 公開日 2020-11-04 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Post-Catalytic Complexes with Emtricitabine or Stavudine and HIV-1 Reverse Transcriptase Reveal New Mechanistic Insights for Nucleotide Incorporation and Drug Resistance. Molecules, 25, 2020
8XBW	The cryo-EM structure of the RAD51 N-terminal lobe domain bound to the histone H4 tail of the nucleosome 分子名称: DNA (5'-D(P*AP*CP*CP*GP*CP*TP*TP*AP*AP*AP*CP*GP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*TP*AP*CP*GP*TP*GP*CP*GP*TP*TP*TP*AP*AP*GP*CP*GP*GP*T)-3'), DNA repair protein RAD51 homolog 1, ... 著者 Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H. 登録日 2023-12-07 公開日 2024-03-27 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site. Nature, 628, 2024

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