6ZJF
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![BU of 6zjf by Molmil](/molmil-images/mine/6zjf) | Crystal structure of STK17B (DRAK2) in complex with AP-229 | 分子名称: | 1,2-ETHANEDIOL, 2-[6-(4-cyclopropylphenyl)thieno[3,2-d]pyrimidin-4-yl]sulfanylethanoic acid, Serine/threonine-protein kinase 17B | 著者 | Chaikuad, A, Picado, A, Willson, T, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2020-06-28 | 公開日 | 2020-07-29 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | A Chemical Probe for Dark Kinase STK17B Derives Its Potency and High Selectivity through a Unique P-Loop Conformation. J.Med.Chem., 63, 2020
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6XKV
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![BU of 6xkv by Molmil](/molmil-images/mine/6xkv) | R. capsulatus cyt bc1 with both FeS proteins in b position (CIII2 b-b) | 分子名称: | Cytochrome b, Cytochrome c1, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Steimle, S, Van Eeuwen, T, Ozturk, Y, Kim, H.J, Braitbard, M, Selamoglu, N, Garcia, B.A, Schneidman-Duhovny, D, Murakami, K, Daldal, F. | 登録日 | 2020-06-27 | 公開日 | 2020-12-30 | 最終更新日 | 2021-07-14 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structures of engineered active bc 1 -cbb 3 type CIII 2 CIV super-complexes and electronic communication between the complexes. Nat Commun, 12, 2021
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6XKT
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![BU of 6xkt by Molmil](/molmil-images/mine/6xkt) | R. capsulatus cyt bc1 with both FeS proteins in c position (CIII2 c-c) | 分子名称: | Cytochrome b, Cytochrome c1, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Steimle, S, Van Eeuwen, T, Ozturk, Y, Kim, H.J, Braitbard, M, Selamoglu, N, Garcia, B.A, Schneidman-Duhovny, D, Murakami, K, Daldal, F. | 登録日 | 2020-06-27 | 公開日 | 2020-12-30 | 最終更新日 | 2021-03-03 | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | 主引用文献 | Cryo-EM structures of engineered active bc 1 -cbb 3 type CIII 2 CIV super-complexes and electronic communication between the complexes. Nat Commun, 12, 2021
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6XKU
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![BU of 6xku by Molmil](/molmil-images/mine/6xku) | R. capsulatus cyt bc1 with one FeS protein in b position and one in c position (CIII2 b-c) | 分子名称: | Cytochrome b, Cytochrome c1, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Steimle, S, Van Eeuwen, T, Ozturk, Y, Kim, H.J, Braitbard, M, Selamoglu, N, Garcia, B.A, Schneidman-Duhovny, D, Murakami, K, Daldal, F. | 登録日 | 2020-06-27 | 公開日 | 2020-12-30 | 最終更新日 | 2021-03-03 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Cryo-EM structures of engineered active bc 1 -cbb 3 type CIII 2 CIV super-complexes and electronic communication between the complexes. Nat Commun, 12, 2021
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6XKZ
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![BU of 6xkz by Molmil](/molmil-images/mine/6xkz) | R. capsulatus CIII2CIV tripartite super-complex, conformation B (SC-1B) | 分子名称: | COPPER (II) ION, Cbb3-type cytochrome c oxidase subunit CcoP,Cytochrome c-type cyt cy, Cytochrome b, ... | 著者 | Steimle, S, Van Eeuwen, T, Ozturk, Y, Kim, H.J, Braitbard, M, Selamoglu, N, Garcia, B.A, Schneidman-Duhovny, D, Murakami, K, Daldal, F. | 登録日 | 2020-06-27 | 公開日 | 2020-12-30 | 最終更新日 | 2021-03-03 | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | 主引用文献 | Cryo-EM structures of engineered active bc 1 -cbb 3 type CIII 2 CIV super-complexes and electronic communication between the complexes. Nat Commun, 12, 2021
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7CFM
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![BU of 7cfm by Molmil](/molmil-images/mine/7cfm) | Cryo-EM structure of the P395-bound GPBAR-Gs complex | 分子名称: | 2-(ethylamino)-6-[3-(4-propan-2-ylphenyl)propanoyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide, CHOLESTEROL, G-protein coupled bile acid receptor 1, ... | 著者 | Yang, F, Mao, C, Guo, L, Lin, J, Ming, Q, Xiao, P, Wu, X, Shen, Q, Guo, S, Shen, D, Lu, R, Zhang, L, Huang, S, Ping, Y, Zhang, C, Ma, C, Zhang, K, Liang, X, Shen, Y, Nan, F, Yi, F, Luca, V, Zhou, J, Jiang, C, Sun, J, Xie, X, Yu, X, Zhang, Y. | 登録日 | 2020-06-27 | 公開日 | 2020-09-09 | 最終更新日 | 2020-12-02 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis of GPBAR activation and bile acid recognition. Nature, 587, 2020
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7CFN
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![BU of 7cfn by Molmil](/molmil-images/mine/7cfn) | Cryo-EM structure of the INT-777-bound GPBAR-Gs complex | 分子名称: | (2S,4R)-4-[(3R,5S,6R,7R,8R,9S,10S,12S,13R,14S,17R)-6-ethyl-10,13-dimethyl-3,7,12-tris(oxidanyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-pentanoic acid, CHOLESTEROL, G-protein coupled bile acid receptor 1, ... | 著者 | Yang, F, Mao, C, Guo, L, Lin, J, Ming, Q, Xiao, P, Wu, X, Shen, Q, Guo, S, Shen, D, Lu, R, Zhang, L, Huang, S, Ping, Y, Zhang, C, Ma, C, Zhang, K, Liang, X, Shen, Y, Nan, F, Yi, F, Luca, V, Zhou, J, Jiang, C, Sun, J, Xie, X, Yu, X, Zhang, Y. | 登録日 | 2020-06-27 | 公開日 | 2020-09-09 | 最終更新日 | 2021-04-07 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis of GPBAR activation and bile acid recognition. Nature, 587, 2020
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6XKW
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![BU of 6xkw by Molmil](/molmil-images/mine/6xkw) | R. capsulatus CIII2CIV bipartite super-complex (SC-2A) with CcoH/cy | 分子名称: | COPPER (II) ION, Cbb3-type cytochrome c oxidase subunit CcoP, Cytochrome b, ... | 著者 | Steimle, S, Van Eeuwen, T, Ozturk, Y, Kim, H.J, Braitbard, M, Selamoglu, N, Garcia, B.A, Schneidman-Duhovny, D, Murakami, K, Daldal, F. | 登録日 | 2020-06-27 | 公開日 | 2020-12-30 | 最終更新日 | 2021-03-03 | 実験手法 | ELECTRON MICROSCOPY (5.2 Å) | 主引用文献 | Cryo-EM structures of engineered active bc 1 -cbb 3 type CIII 2 CIV super-complexes and electronic communication between the complexes. Nat Commun, 12, 2021
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6XKX
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![BU of 6xkx by Molmil](/molmil-images/mine/6xkx) | R. capsulatus CIII2CIV tripartite super-complex, conformation A (SC-1A) | 分子名称: | COPPER (II) ION, Cbb3-type cytochrome c oxidase subunit CcoP,Cytochrome c-type cyt cy, Cytochrome b, ... | 著者 | Steimle, S, Van Eeuwen, T, Ozturk, Y, Kim, H.J, Braitbard, M, Selamoglu, N, Garcia, B.A, Schneidman-Duhovny, D, Murakami, K, Daldal, F. | 登録日 | 2020-06-27 | 公開日 | 2020-12-30 | 最終更新日 | 2021-03-03 | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | 主引用文献 | Cryo-EM structures of engineered active bc 1 -cbb 3 type CIII 2 CIV super-complexes and electronic communication between the complexes. Nat Commun, 12, 2021
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6ZJ2
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![BU of 6zj2 by Molmil](/molmil-images/mine/6zj2) | Structure of RcsB from Salmonella enterica serovar Typhimurium bound to promoter rprA in the presence of phosphomimetic BeF3- | 分子名称: | BERYLLIUM TRIFLUORIDE ION, DNA (5'-D(P*CP*CP*GP*AP*TP*CP*AP*GP*AP*TP*TP*CP*GP*TP*CP*TP*CP*AP*AP*TP*AP*GP*G)-3'), MAGNESIUM ION, ... | 著者 | Huesa, J, Marina, A, Casino, P. | 登録日 | 2020-06-27 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.38 Å) | 主引用文献 | Structure-based analyses of Salmonella RcsB variants unravel new features of the Rcs regulon. Nucleic Acids Res., 49, 2021
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6XKA
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6ZIQ
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![BU of 6ziq by Molmil](/molmil-images/mine/6ziq) | bovine ATP synthase stator domain, state 1 | 分子名称: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C1, ... | 著者 | Spikes, T.E, Montgomery, M.G, Walker, J.E. | 登録日 | 2020-06-26 | 公開日 | 2020-09-09 | 最終更新日 | 2020-09-30 | 実験手法 | ELECTRON MICROSCOPY (4.33 Å) | 主引用文献 | Structure of the dimeric ATP synthase from bovine mitochondria. Proc.Natl.Acad.Sci.USA, 117, 2020
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6ZIO
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6ZIZ
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![BU of 6ziz by Molmil](/molmil-images/mine/6ziz) | CRYSTAL STRUCTURE OF NRAS Q61R IN COMPLEX WITH GTP AND COMPOUND 18 | 分子名称: | (3~{S})-3-[2-[(dimethylamino)methyl]-1~{H}-indol-3-yl]-5-oxidanyl-2,3-dihydroisoindol-1-one, GTPase NRas, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Kessler, D, Fischer, G, Boettcher, J. | 登録日 | 2020-06-26 | 公開日 | 2020-08-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.785 Å) | 主引用文献 | Drugging all RAS isoforms with one pocket. Future Med Chem, 12, 2020
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6ZIY
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![BU of 6ziy by Molmil](/molmil-images/mine/6ziy) | Respiratory complex I from Thermus thermophilus, NADH dataset, major state | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... | 著者 | Kaszuba, K, Tambalo, M, Gallagher, G.T, Sazanov, L.A. | 登録日 | 2020-06-26 | 公開日 | 2020-09-02 | 実験手法 | ELECTRON MICROSCOPY (4.25 Å) | 主引用文献 | Key role of quinone in the mechanism of respiratory complex I. Nat Commun, 11, 2020
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6ZIT
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![BU of 6zit by Molmil](/molmil-images/mine/6zit) | bovine ATP synthase Stator domain, state 2 | 分子名称: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C2, ... | 著者 | Spikes, T.E, Montgomery, M.G, Walker, J.E. | 登録日 | 2020-06-26 | 公開日 | 2020-09-09 | 最終更新日 | 2020-09-30 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | Structure of the dimeric ATP synthase from bovine mitochondria. Proc.Natl.Acad.Sci.USA, 117, 2020
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6ZIR
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![BU of 6zir by Molmil](/molmil-images/mine/6zir) | CRYSTAL STRUCTURE OF NRAS (C118S) IN COMPLEX WITH GDP AND COMPOUND 18 | 分子名称: | (3~{S})-3-[2-[(dimethylamino)methyl]-1~{H}-indol-3-yl]-5-oxidanyl-2,3-dihydroisoindol-1-one, GTPase NRas, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Kessler, D, Fischer, G, Boettcher, J. | 登録日 | 2020-06-26 | 公開日 | 2020-08-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Drugging all RAS isoforms with one pocket. Future Med Chem, 12, 2020
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6ZIW
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![BU of 6ziw by Molmil](/molmil-images/mine/6ziw) | The IRAK3 Pseudokinase Domain Bound To ATPgammaS | 分子名称: | Interleukin-1 receptor-associated kinase 3, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, SULFATE ION | 著者 | Mathea, S, Chatterjee, D, Preuss, F, Kraemer, A, Knapp, S. | 登録日 | 2020-06-26 | 公開日 | 2020-07-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | The IRAK3 Pseudokinase Domain Bound To ATPgammaS To Be Published
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6ZJ0
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![BU of 6zj0 by Molmil](/molmil-images/mine/6zj0) | CRYSTAL STRUCTURE OF HRAS-G12D IN COMPLEX WITH GCP AND COMPOUND 18 | 分子名称: | (3~{S})-3-[2-[(dimethylamino)methyl]-1~{H}-indol-3-yl]-5-oxidanyl-2,3-dihydroisoindol-1-one, GTPase HRas, MAGNESIUM ION, ... | 著者 | Kessler, D, Fischer, G, Boettcher, J. | 登録日 | 2020-06-26 | 公開日 | 2020-08-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.763 Å) | 主引用文献 | Drugging all RAS isoforms with one pocket. Future Med Chem, 12, 2020
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6ZIU
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![BU of 6ziu by Molmil](/molmil-images/mine/6ziu) | bovine ATP synthase stator domain, state 3 | 分子名称: | ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase protein 8, ... | 著者 | Spikes, T.E, Montgomery, M.G, Walker, J.E. | 登録日 | 2020-06-26 | 公開日 | 2020-09-09 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (6.02 Å) | 主引用文献 | Structure of the dimeric ATP synthase from bovine mitochondria. Proc.Natl.Acad.Sci.USA, 117, 2020
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6ZIN
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![BU of 6zin by Molmil](/molmil-images/mine/6zin) | Crystal structure of the neurotensin receptor 1 in complex with the small molecule inverse agonist SR48692 | 分子名称: | 2-[[1-(7-chloranylquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazol-3-yl]carbonylamino]adamantane-2-carboxylic acid, Neurotensin receptor type 1,DARPin,HRV 3C protease recognition sequence | 著者 | Deluigi, M, Klipp, A, Hilge, M, Merklinger, L, Klenk, C, Plueckthun, A. | 登録日 | 2020-06-26 | 公開日 | 2021-02-10 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.639 Å) | 主引用文献 | Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism. Sci Adv, 7, 2021
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6ZIX
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![BU of 6zix by Molmil](/molmil-images/mine/6zix) | Structure of RcsB from Salmonella enterica serovar Typhimurium bound to promoter P1flhDC in the presence of phosphomimetic BeF3- | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, P1flhDC promoter sequence of 23 bp, ... | 著者 | Huesa, J, Marina, A, Casino, P. | 登録日 | 2020-06-26 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structure-based analyses of Salmonella RcsB variants unravel new features of the Rcs regulon. Nucleic Acids Res., 49, 2021
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6ZIL
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6ZII
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6ZI7
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![BU of 6zi7 by Molmil](/molmil-images/mine/6zi7) | Crystal structure of OleP-oleandolide(DEO) bound to L-rhamnose | 分子名称: | (3~{R},4~{S},5~{R},6~{S},7~{S},9~{S},11~{R},12~{S},13~{R},14~{R})-3,5,7,9,11,13,14-heptamethyl-4,6,12-tris(oxidanyl)-1-oxacyclotetradecane-2,10-dione, Cytochrome P-450, FORMIC ACID, ... | 著者 | Montemiglio, L.C, Savino, C, Vallone, B, Parisi, G, Freda, I. | 登録日 | 2020-06-25 | 公開日 | 2020-10-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Dissecting the Cytochrome P450 OleP Substrate Specificity: Evidence for a Preferential Substrate. Biomolecules, 10, 2020
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