2CC1
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2BLS
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2BLM
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2B5R
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![BU of 2b5r by Molmil](/molmil-images/mine/2b5r) | 1B Lactamase / B Lactamase Inhibitor | 分子名称: | Beta-lactamase TEM, Beta-lactamase inhibitory protein | 著者 | Rahat, O, Albeck, S, Meged, R, Dym, O, Screiber, G, Israel Structural Proteomics Center (ISPC) | 登録日 | 2005-09-29 | 公開日 | 2006-04-11 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Binding Hot Spots in the TEM1-BLIP Interface in Light of its Modular Architecture. J.Mol.Biol., 102, 2006
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2A49
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![BU of 2a49 by Molmil](/molmil-images/mine/2a49) | Crystal structure of clavulanic acid bound to E166A variant of SHV-1 beta-lactamase | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, ... | 著者 | Padayatti, P.S, Helfand, M.S, Totir, M.A, Carey, M.P, Carey, P.R, Bonomo, R.A, van den Akker, F. | 登録日 | 2005-06-28 | 公開日 | 2005-08-02 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | High Resolution Crystal Structures of the trans-Enamine Intermediates Formed by Sulbactam and Clavulanic Acid and E166A SHV-1 {beta}-Lactamase. J.Biol.Chem., 280, 2005
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2A3U
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![BU of 2a3u by Molmil](/molmil-images/mine/2a3u) | Crystal structure of sulbactam bound to E166A variant of SHV-1 beta-lactamase | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, ... | 著者 | Padayatti, P.S, Helfand, M.S, Totir, M.A, Carey, M.P, Carey, P.R, Bonomo, R.A, van den Akker, F. | 登録日 | 2005-06-27 | 公開日 | 2005-08-02 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | High Resolution Crystal Structures of the trans-Enamine Intermediates Formed by Sulbactam and Clavulanic Acid and E166A SHV-1 {beta}-Lactamase. J.Biol.Chem., 280, 2005
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1ZKJ
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![BU of 1zkj by Molmil](/molmil-images/mine/1zkj) | Structural Basis for the Extended Substrate Spectrum of CMY-10, a Plasmid-Encoded Class C beta-lactamase | 分子名称: | ACETIC ACID, ZINC ION, extended-spectrum beta-lactamase | 著者 | Cha, S.S, Jung, H.I, An, Y.J, Lee, S.H. | 登録日 | 2005-05-03 | 公開日 | 2006-04-18 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural basis for the extended substrate spectrum of CMY-10, a plasmid-encoded class C beta-lactamase. Mol.Microbiol., 60, 2006
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1ZG6
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![BU of 1zg6 by Molmil](/molmil-images/mine/1zg6) | TEM1 beta lactamase mutant S70G | 分子名称: | Beta-lactamase TEM | 著者 | Stec, B, Holtz, K.M, Wojciechowski, C.L, Kantrowitz, E.R. | 登録日 | 2005-04-20 | 公開日 | 2005-05-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of the wild-type TEM-1 beta-lactamase at 1.55 A and the mutant enzyme Ser70Ala at 2.1 A suggest the mode of noncovalent catalysis for the mutant enzyme. Acta Crystallogr.,Sect.D, 61, 2005
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1ZG4
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![BU of 1zg4 by Molmil](/molmil-images/mine/1zg4) | TEM1 beta lactamase | 分子名称: | Beta-lactamase TEM | 著者 | Stec, B, Holtz, K.M, Wojciechowski, C.L, Kantrowitz, E.R. | 登録日 | 2005-04-20 | 公開日 | 2005-05-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structure of the wild-type TEM-1 beta-lactamase at 1.55 A and the mutant enzyme Ser70Ala at 2.1 A suggest the mode of noncovalent catalysis for the mutant enzyme. Acta Crystallogr.,Sect.D, 61, 2005
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1ZC2
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![BU of 1zc2 by Molmil](/molmil-images/mine/1zc2) | Crystal Structure of plasmid-encoded class C beta-lactamase CMY-2 complexed with citrate molecule | 分子名称: | CITRIC ACID, beta-lactamase class C | 著者 | Bauvois, C, Jacquamet, L, Fieulaine, S, Frere, J.-M, Galleni, M, Ferrer, J.-L. | 登録日 | 2005-04-10 | 公開日 | 2006-04-25 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Crystallographic structure of plasmid-encoded CMY-2 beta-lactamase revealed citrate molecule in the active site. To be Published
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1YT4
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![BU of 1yt4 by Molmil](/molmil-images/mine/1yt4) | Crystal structure of TEM-76 beta-lactamase at 1.4 Angstrom resolution | 分子名称: | Beta-lactamase TEM | 著者 | Thomas, V.L, Golemi-Kotra, D, Kim, C, Vakulenko, S.B, Mobashery, S, Shoichet, B.K. | 登録日 | 2005-02-09 | 公開日 | 2005-07-12 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural Consequences of the Inhibitor-Resistant Ser130Gly Substitution in TEM beta-Lactamase. Biochemistry, 44, 2005
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1YQS
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![BU of 1yqs by Molmil](/molmil-images/mine/1yqs) | Inhibition of the R61 DD-Peptidase by N-benzoyl-beta-sultam | 分子名称: | 2-(BENZOYLAMINO)ETHANESULFONIC ACID, D-alanyl-D-alanine carboxypeptidase, GLYCEROL | 著者 | Ahmed, N, Cordaro, M, Laws, A.P, Delmarcelle, M, Silvaggi, N.R, Kelly, J.A, Page, M.I. | 登録日 | 2005-02-02 | 公開日 | 2005-06-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | Inactivation of Bacterial dd-Peptidase by beta-Sultams. Biochemistry, 44, 2005
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1YMX
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![BU of 1ymx by Molmil](/molmil-images/mine/1ymx) | X-ray crystallographic structure of CTX-M-9 beta-lactamase covalently linked to cefoxitin | 分子名称: | (2R)-5-[(carbamoyloxy)methyl]-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, beta-lactamase CTX-M-9 | 著者 | Chen, Y, Shoichet, B, Bonnet, R. | 登録日 | 2005-01-21 | 公開日 | 2005-04-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases. J.Am.Chem.Soc., 127, 2005
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1YMS
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![BU of 1yms by Molmil](/molmil-images/mine/1yms) | X-ray crystallographic structure of CTX-M-9 beta-lactamase complexed with nafcinin-like boronic acid inhibitor | 分子名称: | [(2-ETHOXY-1-NAPHTHOYL)AMINO]METHYLBORONIC ACID, beta-lactamase CTX-M-9 | 著者 | Chen, Y, Shoichet, B, Bonnet, R. | 登録日 | 2005-01-21 | 公開日 | 2005-04-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases. J.Am.Chem.Soc., 127, 2005
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1YM1
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![BU of 1ym1 by Molmil](/molmil-images/mine/1ym1) | X-ray crystallographic structure of CTX-M-9 beta-lactamase complexed with a boronic acid inhibitor (SM2) | 分子名称: | (1R)-1-(2-THIENYLACETYLAMINO)-1-(3-CARBOXYPHENYL)METHYLBORONIC ACID, PHOSPHATE ION, beta-lactamase CTX-M-9a | 著者 | Chen, Y, Shoichet, B, Bonnet, R. | 登録日 | 2005-01-20 | 公開日 | 2005-04-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases. J.Am.Chem.Soc., 127, 2005
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1YLZ
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![BU of 1ylz by Molmil](/molmil-images/mine/1ylz) | X-ray crystallographic structure of CTX-M-14 beta-lactamase complexed with ceftazidime-like boronic acid | 分子名称: | BETA-LACTAMASE CTX-M-14, PHOSPHATE ION, PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE | 著者 | Chen, Y, Shoichet, B, Bonnet, R. | 登録日 | 2005-01-19 | 公開日 | 2005-04-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases. J.Am.Chem.Soc., 127, 2005
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1YLY
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![BU of 1yly by Molmil](/molmil-images/mine/1yly) | X-ray crystallographic structure of CTX-M-9 beta-lactamase complexed with ceftazidime-like boronic acid | 分子名称: | PHOSPHATE ION, PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE, beta-lactamase CTX-M-9 | 著者 | Chen, Y, Shoichet, B, Bonnet, R. | 登録日 | 2005-01-19 | 公開日 | 2005-04-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases. J.Am.Chem.Soc., 127, 2005
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1YLW
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![BU of 1ylw by Molmil](/molmil-images/mine/1ylw) | X-ray structure of CTX-M-16 beta-lactamase | 分子名称: | CTX-M-16 beta-lactamase, SULFATE ION | 著者 | Chen, Y, Delmas, J, Sirot, J, Shoichet, B, Bonnet, R. | 登録日 | 2005-01-19 | 公開日 | 2005-04-19 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Atomic Resolution Structures of CTX-M beta-Lactamases: Extended Spectrum Activities from Increased Mobility and Decreased Stability. J.Mol.Biol., 348, 2005
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1YLT
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![BU of 1ylt by Molmil](/molmil-images/mine/1ylt) | Atomic resolution structure of CTX-M-14 beta-lactamase | 分子名称: | SULFATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, beta-lactamase CTX-M-14 | 著者 | Chen, Y, Delmas, J, Sirot, J, Shoichet, B, Bonnet, R. | 登録日 | 2005-01-19 | 公開日 | 2005-04-19 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Atomic Resolution Structures of CTX-M beta-Lactamases: Extended Spectrum Activities from Increased Mobility and Decreased Stability. J.Mol.Biol., 348, 2005
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1YLP
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![BU of 1ylp by Molmil](/molmil-images/mine/1ylp) | Atomic resolution structure of CTX-M-27 beta-lactamase | 分子名称: | SULFATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, beta-lactamase CTX-M-27 | 著者 | Chen, Y, Delmas, J, Sirot, J, Shoichet, B, Bonnet, R. | 登録日 | 2005-01-19 | 公開日 | 2005-04-19 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Atomic Resolution Structures of CTX-M beta-Lactamases: Extended Spectrum Activities from Increased Mobility and Decreased Stability. J.Mol.Biol., 348, 2005
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1YLJ
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![BU of 1ylj by Molmil](/molmil-images/mine/1ylj) | Atomic resolution structure of CTX-M-9 beta-lactamase | 分子名称: | SULFATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, beta-lactamase CTX-M-9a | 著者 | Chen, Y, Delmas, J, Sirot, J, Shoichet, B, Bonnet, R. | 登録日 | 2005-01-19 | 公開日 | 2005-04-19 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (0.98 Å) | 主引用文献 | Atomic Resolution Structures of CTX-M beta-Lactamases: Extended Spectrum Activities from Increased Mobility and Decreased Stability. J.Mol.Biol., 348, 2005
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1Y54
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![BU of 1y54 by Molmil](/molmil-images/mine/1y54) | Crystal structure of the native class C beta-lactamase from Enterobacter cloacae 908R complexed with BRL42715 | 分子名称: | (7R)-6-FORMYL-7-(1-METHYL-1H-1,2,3-TRIAZOL-4-YL)-4,7-DIHYDRO-1,4-THIAZEPINE-3-CARBOXYLIC ACID, Beta-lactamase | 著者 | Michaux, C, Charlier, P, Frere, J.-M, Wouters, J. | 登録日 | 2004-12-02 | 公開日 | 2005-03-29 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of BRL 42715, C6-(N1-Methyl-1,2,3-triazolylmethylene)penem, in Complex with Enterobactercloacae 908R beta-Lactamase: Evidence for a Stereoselective Mechanism from Docking Studies J.Am.Chem.Soc., 127, 2005
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1XXM
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![BU of 1xxm by Molmil](/molmil-images/mine/1xxm) | The modular architecture of protein-protein binding site | 分子名称: | Beta-lactamase TEM, Beta-lactamase inhibitory protein, CALCIUM ION | 著者 | Reichmann, D, Rahat, O, Albeck, S, Meged, R, Dym, O, Schreiber, G, Israel Structural Proteomics Center (ISPC) | 登録日 | 2004-11-07 | 公開日 | 2005-01-18 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The modular architecture of protein-protein binding interfaces Proc.Natl.Acad.Sci.USA, 102, 2005
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1XX2
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![BU of 1xx2 by Molmil](/molmil-images/mine/1xx2) | Refinement of P99 beta-lactamase from Enterobacter cloacae | 分子名称: | Beta-lactamase | 著者 | Knox, J.R, Sun, T. | 登録日 | 2004-11-03 | 公開日 | 2004-11-23 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Crystallographic structure of a phosphonate derivative of the Enterobacter cloacae P99 cephalosporinase: mechanistic interpretation of a beta-lactamase transition-state analog. Biochemistry, 33, 1994
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1XPB
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![BU of 1xpb by Molmil](/molmil-images/mine/1xpb) | STRUCTURE OF BETA-LACTAMASE TEM1 | 分子名称: | BETA-LACTAMASE, SULFATE ION | 著者 | Fonze, E, Charlier, P. | 登録日 | 1997-01-10 | 公開日 | 1997-04-01 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | TEM1 beta-lactamase structure solved by molecular replacement and refined structure of the S235A mutant. Acta Crystallogr.,Sect.D, 51, 1995
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