PDB: 974 件ウェブページステータス検索Chemie searchBIRD

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3C5A	Crystal structure of the C-terminal deleted mutant of the class A carbapenemase KPC-2 at 1.23 angstrom 分子名称: CITRIC ACID, Class A carbapenemase KPC-2 著者 Petrella, S, Ziental-Gelus, N, Mayer, C, Jarlier, V, Sougakoff, W. 登録日 2008-01-31 公開日 2008-08-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 Genetic and structural insights into the dissemination potential of the extremely-broad-spectrum class A {beta}-lactamase (EBSBL) KPC-2 identified in two strains of Escherichia coli and Enterobacter cloacae isolated from the same patient in France ANTIMICROB.AGENTS CHEMOTHER., 2008
4MEZ	Crystal structure of M68L/M69T double mutant TEM-1 分子名称: Beta-lactamase TEM, CHLORIDE ION, GLYCEROL, ... 著者 Park, J, Gobeil, S, Pelletier, J.N, Berghuis, A.M. 登録日 2013-08-27 公開日 2014-10-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.047 Å) 主引用文献 The Structural Dynamics of Engineered beta-Lactamases Vary Broadly on Three Timescales yet Sustain Native Function. Sci Rep, 9, 2019
1LHY	Crystal structure of TEM-30 beta-Lactamase at 2.0 Angstrom 分子名称: Class A beta-Lactamase- TEM 30, PHOSPHATE ION 著者 Wang, X, Minasov, G, Shoichet, B.K. 登録日 2002-04-17 公開日 2002-09-11 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The structural bases of antibiotic resistance in the clinically derived mutant beta-lactamases TEM-30, TEM-32, and TEM-34. J.Biol.Chem., 277, 2002
3BFE	Crystal Structure of the Class A beta-lactamase SED-1 from Citrobacter sedlakii 分子名称: Class A beta-lactamase Sed1, THIOCYANATE ION 著者 Pernot, L, Petrella, S, Sougakoff, W. 登録日 2007-11-21 公開日 2007-12-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 acyl-intermediate structures of the class A beta-lactamase SED-G238C To be Published
3BFD	Crystal Structure of the Class A beta-lactamase SED-G238C mutant from Citrobacter sedlakii 分子名称: CACODYLATE ION, Class A beta-lactamase Sed1 著者 Pernot, L, Petrella, S, Sougakoff, W. 登録日 2007-11-21 公開日 2007-12-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 acyl-intermediate structures of the class A beta-lactamase SED-G238C To be Published
2ZQ8	Apo structure of class a beta-lactamase Toho-1 R274N/R276N double mutant 分子名称: Beta-lactamase Toho-1, SULFATE ION 著者 Shimamura, T, Nitanai, Y, Uchiyama, T, Ago, H, Matsuzawa, H, Miyano, M. 登録日 2008-08-07 公開日 2009-07-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.03 Å) 主引用文献 Improvement of crystal quality by surface mutations of beta-lactamase Toho-1 Acta Crystallogr.,Sect.F, 65, 2009
1M40	ULTRA HIGH RESOLUTION CRYSTAL STRUCTURE OF TEM-1 分子名称: BETA-LACTAMASE TEM, PHOSPHATE ION, PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE, ... 著者 Minasov, G, Wang, X, Shoichet, B.K. 登録日 2002-07-01 公開日 2002-07-17 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (0.85 Å) 主引用文献 An ultrahigh resolution structure of TEM-1 beta-lactamase suggests a role for Glu166 as the general base in acylation. J.Am.Chem.Soc., 124, 2002
4MBH	Penam sulfone PSR-3-226 bound to E166A variant of SHV-1 beta-lactamase 分子名称: 3-(formylamino)-L-alanine, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase SHV-1, ... 著者 Rodkey, E.A, van den Akker, F. 登録日 2013-08-19 公開日 2014-07-30 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 Penam sulfones and beta-lactamase inhibition: SA2-13 and the importance of the C2 side chain length and composition. Plos One, 9, 2014
2ZQ7	Apo structure of Class A beta-lactamase Toho-1 E166A/R274N/R276N triple mutant 分子名称: Beta-lactamase Toho-1, SULFATE ION 著者 Shimamura, T, Nitanai, Y, Uchiyama, T, Ago, H, Matsuzawa, H, Miyano, M. 登録日 2008-08-07 公開日 2009-07-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (0.94 Å) 主引用文献 Improvement of the Crystal Quality by the Surface Mutations on a Beta-Lactamase Toho-1 To be Published
2ZQA	Cefotaxime acyl-intermediate structure of class a beta-lacta Toho-1 E166A/R274N/R276N triple mutant 分子名称: Beta-lactamase Toho-1, CEFOTAXIME, C3' cleaved, ... 著者 Nitanai, Y, Shimamura, T, Uchiyama, T, Ishii, Y, Takehira, M, Yutani, K, Matsuzawa, H, Miyano, M. 登録日 2008-08-07 公開日 2009-07-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 Structural Basis of Extend Spectrum Beta-Lactamase in Correlation of Enzymatic Kinetics and Thermal Stability of Acyl-Intermediates To be Published
4MBF	Crystal structure of Penam sulfone PSR-4-157 bound to SHV-1 beta-lactamase 分子名称: 6-({(2R,3S)-3-carboxy-2-methyl-3-[(3-oxopropyl)amino]-2-sulfinopropyl}oxy)-6-oxohexanoic acid, Beta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE 著者 Rodkey, E.A, van den Akker, F. 登録日 2013-08-19 公開日 2014-07-30 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Penam sulfones and beta-lactamase inhibition: SA2-13 and the importance of the C2 side chain length and composition. Plos One, 9, 2014
3BYD	Crystal structure of beta-lactamase OXY-1-1 from Klebsiella oxytoca 分子名称: ACETATE ION, Beta-lactamase OXY-1, SULFATE ION 著者 Liang, Y.-H, Wu, S.W, Su, X.-D. 登録日 2008-01-15 公開日 2009-01-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structural insights into the broadened substrate profile of the extended-spectrum beta-lactamase OXY-1-1 from Klebsiella oxytoca Acta Crystallogr.,Sect.D, 68, 2012
3C7U	Structural Insight into the Kinetics and Cp of interactions between TEM-1-Lactamase and BLIP 分子名称: Beta-lactamase, Beta-lactamase inhibitory protein 著者 Wang, J, Chow, D.-C. 登録日 2008-02-08 公開日 2008-10-07 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural insight into the kinetics and DeltaCp of interactions between TEM-1 beta-lactamase and beta-lactamase inhibitory protein (BLIP) J.Biol.Chem., 284, 2009
3BFC	class A beta-lactamase SED-G238C complexed with imipenem 分子名称: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, Class A beta-lactamase Sed1 著者 Pernot, L, Petrella, S, Sougakoff, W. 登録日 2007-11-21 公開日 2007-12-18 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Acyl-intermediate structures of the class A beta-lactamase SED-G238C To be Published
4OPR	Crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying G238S mutation 分子名称: CALCIUM ION, SULFATE ION, TEM-94 ES-beta-lactamase, ... 著者 Dellus-Gur, E, Elias, M, Fraser, J.S, Tawfik, D.S. 登録日 2014-02-06 公開日 2015-05-20 最終更新日 2018-01-17 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Negative Epistasis and Evolvability in TEM-1 beta-Lactamase--The Thin Line between an Enzyme's Conformational Freedom and Disorder. J. Mol. Biol., 427, 2015
4OQ0	Crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying R164S/G238S mutation in complex with boron-based inhibitor EC25 分子名称: 1,2-ETHANEDIOL, 3-[(2R)-2-{[(2R)-2-amino-2-phenylacetyl]amino}-2-(dihydroxyboranyl)ethyl]benzoic acid, CALCIUM ION, ... 著者 Dellus-Gur, E, Elias, M, Fraser, J.S, Tawfik, D.S. 登録日 2014-02-07 公開日 2015-05-20 最終更新日 2018-01-17 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Negative Epistasis and Evolvability in TEM-1 beta-Lactamase--The Thin Line between an Enzyme's Conformational Freedom and Disorder. J. Mol. Biol., 427, 2015
4OQG	Crystal structure of TEM-1 beta-lactamase in complex with boron-based inhibitor EC25 分子名称: 3-[(2R)-2-{[(2R)-2-amino-2-phenylacetyl]amino}-2-(dihydroxyboranyl)ethyl]benzoic acid, Ampicillin resistance protein, ZINC ION 著者 Dellus-Gur, E, Elias, M, Fraser, J.S, Tawfik, D.S. 登録日 2014-02-09 公開日 2015-05-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Negative Epistasis and Evolvability in TEM-1 beta-Lactamase--The Thin Line between an Enzyme's Conformational Freedom and Disorder. J. Mol. Biol., 427, 2015
3BLM	REFINED CRYSTAL STRUCTURE OF BETA-LACTAMASE FROM STAPHYLOCOCCUS AUREUS PC1 AT 2.0 分子名称: BETA-LACTAMASE 著者 Herzberg, O, Moult, J. 登録日 1990-12-03 公開日 1991-01-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Refined crystal structure of beta-lactamase from Staphylococcus aureus PC1 at 2.0 A resolution. J.Mol.Biol., 217, 1991
3CG5	Crystal Structure of the Covalent Adduct Formed between TB B-lactamase and Clavulanate 分子名称: (2E)-3-[(4-hydroxy-2-oxobutyl)amino]prop-2-enal, Beta-lactamase, PHOSPHATE ION 著者 Tremblay, L.W, Hugonnet, J.E, Blanchard, J.S. 登録日 2008-03-04 公開日 2008-05-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure of the covalent adduct formed between Mycobacterium tuberculosis beta-lactamase and clavulanate. Biochemistry, 47, 2008
4OP8	Room temperature crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying G238S mutation 分子名称: CALCIUM ION, SULFATE ION, TEM-94 ES-beta-lactamase, ... 著者 Dellus-Gur, E, Elias, M, Fraser, J.S, Tawfik, D.S. 登録日 2014-02-05 公開日 2015-05-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Negative Epistasis and Evolvability in TEM-1 beta-Lactamase--The Thin Line between an Enzyme's Conformational Freedom and Disorder. J. Mol. Biol., 427, 2015
4OPQ	Room temperature crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying R164S/G238S mutations 分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... 著者 Dellus-Gur, E, Elias, M, Fraser, J.S, Tawfik, D.S. 登録日 2014-02-06 公開日 2015-05-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Negative Epistasis and Evolvability in TEM-1 beta-Lactamase--The Thin Line between an Enzyme's Conformational Freedom and Disorder. J. Mol. Biol., 427, 2015
4OPZ	Crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying G238S mutation in complex with boron-based inhibitor EC25 分子名称: 1,2-ETHANEDIOL, 3-[(2R)-2-{[(2R)-2-amino-2-phenylacetyl]amino}-2-(dihydroxyboranyl)ethyl]benzoic acid, ACETATE ION, ... 著者 Dellus-Gur, E, Elias, M, Fraser, J.S, Tawfik, D.S. 登録日 2014-02-07 公開日 2015-05-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Negative Epistasis and Evolvability in TEM-1 beta-Lactamase--The Thin Line between an Enzyme's Conformational Freedom and Disorder. J. Mol. Biol., 427, 2015
1KGE	STRUCTURE OF BETA-LACTAMASE ASN 170 MET MUTANT 分子名称: BETA-LACTAMASE 著者 Chen, C.C.H, Zawadzke, L.E, Herzberg, O. 登録日 1996-10-17 公開日 1997-04-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Elimination of the hydrolytic water molecule in a class A beta-lactamase mutant: crystal structure and kinetics. Biochemistry, 35, 1996
1N4O	Crystal structure of the Class A beta-lactamase L2 from Stenotrophomonas maltophilia 分子名称: L2 beta-lactamase, SULFATE ION 著者 Pernot, L, Petrella, S, Sougakoff, W. 登録日 2002-11-01 公開日 2003-11-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Role of the disulfide bridge Cys69-Cys238 in class A b-lactamases : a structural and biochemical investigation on the b-lactamase L2 from Stenotrophomonas maltophilia To be Published
3C4O	Crystal Structure of the SHV-1 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) E73M/S130K/S146M complex 分子名称: Beta-lactamase SHV-1, Beta-lactamase inhibitory protein, SULFATE ION 著者 Reynolds, K.A, Hanes, M.S, Thomson, J.M, Antczak, A.J, Berger, J.M, Bonomo, R.A, Kirsch, J.F, Handel, T.M. 登録日 2008-01-30 公開日 2008-05-27 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Computational redesign of the SHV-1 beta-lactamase/beta-lactamase inhibitor protein interface. J.Mol.Biol., 382, 2008

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