4B40
 
 | | Probing the active center of catalase-phenol oxidase from Scytalidium thermophilum | | 分子名称: | CALCIUM ION, CATALASE-PHENOL OXIDASE, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE | | 著者 | Yuzugullu, Y, Trinh, C.H, Pearson, A.R, Ogel, Z.B, McPherson, M.J. | | 登録日 | 2012-07-27 | | 公開日 | 2013-04-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Investigating the Active Centre of the Scytalidium Thermophilum Catalase
Acta Crystallogr.,Sect.F, 69, 2013
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8T9H
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8TDM
 | | Cryo-EM structure of AtMSL10-K539E | | 分子名称: | Mechanosensitive ion channel protein 10 | | 著者 | Zhang, J, Yuan, P. | | 登録日 | 2023-07-03 | | 公開日 | 2023-10-18 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Open structure and gating of the Arabidopsis mechanosensitive ion channel MSL10.
Nat Commun, 14, 2023
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6DF2
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8PEU
 | | Rho-ATPgS-Psu complex I | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Polarity suppression protein, ... | | 著者 | Gjorgjevikj, D, Wahl, M.C, Hilal, T, Loll, B. | | 登録日 | 2023-06-15 | | 公開日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Rho-ATPgS-Psu complex I
To Be Published
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8PEY
 | | Rho P167L-ATPgS-Psu complex II | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Polarity suppression protein, ... | | 著者 | Gjorgjevikj, D, Wahl, M.C, Hilal, T, Loll, B. | | 登録日 | 2023-06-15 | | 公開日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Rho P167L-ATPgS-Psu complex II
To Be Published
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5LLD
 | | Flavodiiron core of Escherichia coli flavorubredoxin in the reduced form. | | 分子名称: | Anaerobic nitric oxide reductase flavorubredoxin, FE (III) ION, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Romao, C.V, Borges, P.T, Vicente, J.B, Carrondo, M.A, Teixeira, M, Frazao, C. | | 登録日 | 2016-07-27 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.651 Å) | | 主引用文献 | Structure of Escherichia coli Flavodiiron Nitric Oxide Reductase.
J.Mol.Biol., 428, 2016
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8PEX
 | | Rho P167L-ATPgS-Psu complex I | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Polarity suppression protein, ... | | 著者 | Gjorgjevikj, D, Wahl, M.C, Hilal, T, Loll, B. | | 登録日 | 2023-06-15 | | 公開日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Rho P167L-ATPgS-Psu complex I
To Be Published
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8PEW
 | | Rho-ATPgS-Psu complex II | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Polarity suppression protein, ... | | 著者 | Gjorgjevikj, D, Wahl, M.C, Hilal, T, Loll, B. | | 登録日 | 2023-06-15 | | 公開日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Rho-ATPgS-Psu complex II
To Be Published
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5K9C
 | | Crystal structure of human dihydroorotate dehydrogenase with ML390 | | 分子名称: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, ACETATE ION, CHLORIDE ION, ... | | 著者 | Lewis, T.A, Sykes, D.B, Law, J.M, Munoz, B, Scadden, D.T, Rustiguel, J.K, Nonato, M.C, Schreiber, S.L. | | 登録日 | 2016-05-31 | | 公開日 | 2016-10-12 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia.
ACS Med Chem Lett, 7, 2016
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5LXX
 | | High-resolution structure of human collapsin response mediator protein 2 | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dihydropyrimidinase-related protein 2, SULFATE ION | | 著者 | Myllykoski, M, Hensley, K, Kursula, P. | | 登録日 | 2016-09-23 | | 公開日 | 2017-01-11 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Collapsin response mediator protein 2: high-resolution crystal structure sheds light on small-molecule binding, post-translational modifications, and conformational flexibility.
Amino Acids, 49, 2017
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6UTW
 | | E. coli sigma-S transcription initiation complex with a 4-nt RNA ("Fresh" crystal) | | 分子名称: | DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Zuo, Y, De, S, Steitz, T.A. | | 登録日 | 2019-10-30 | | 公開日 | 2020-08-26 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.854 Å) | | 主引用文献 | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
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8TDJ
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6FF4
 | | human Bact spliceosome core structure | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | | 著者 | Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. | | 登録日 | 2018-01-03 | | 公開日 | 2018-08-29 | | 最終更新日 | 2020-10-07 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
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8TDL
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8TDK
 | | Cryo-EM structure of AtMSL10-G556V | | 分子名称: | Mechanosensitive ion channel protein 10 | | 著者 | Zhang, J, Yuan, P. | | 登録日 | 2023-07-03 | | 公開日 | 2023-10-18 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Open structure and gating of the Arabidopsis mechanosensitive ion channel MSL10.
Nat Commun, 14, 2023
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4B5K
 | | Probing the active center of catalase-phenol oxidase from Scytalidium thermophilum | | 分子名称: | CALCIUM ION, CATALASE-PHENOL OXIDASE, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE | | 著者 | Yuzugullu, Y, Trinh, C.H, Pearson, A.R, Ogel, Z.B, McPherson, M.J. | | 登録日 | 2012-08-03 | | 公開日 | 2013-04-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Investigating the Active Centre of the Scytalidium Thermophilum Catalase
Acta Crystallogr.,Sect.F, 69, 2013
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2FV2
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5L1Z
 | | TAR complex with HIV-1 Tat-AFF4-P-TEFb | | 分子名称: | AF4/FMR2 family member 4, Cyclin-T1, Cyclin-dependent kinase 9, ... | | 著者 | Schulze-Gahmen, U, Hurley, J. | | 登録日 | 2016-07-29 | | 公開日 | 2016-10-26 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (5.9 Å) | | 主引用文献 | Insights into HIV-1 proviral transcription from integrative structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex.
Elife, 5, 2016
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7K0K
 | | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa, 3KS-bound | | 分子名称: | 3-Dehydrosphinganine, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | | 著者 | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | | 登録日 | 2020-09-04 | | 公開日 | 2021-02-24 | | 最終更新日 | 2021-03-24 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
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7K0N
 | | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 2 | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | | 登録日 | 2020-09-04 | | 公開日 | 2021-02-24 | | 最終更新日 | 2021-03-24 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
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7K0O
 | | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 3 | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | | 登録日 | 2020-09-04 | | 公開日 | 2021-02-24 | | 最終更新日 | 2021-03-24 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
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7K0J
 | | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa protomer | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | | 著者 | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | | 登録日 | 2020-09-04 | | 公開日 | 2021-02-24 | | 最終更新日 | 2021-03-24 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
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7K0Q
 | | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, myriocin-bound | | 分子名称: | Myriocin, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | | 登録日 | 2020-09-04 | | 公開日 | 2021-02-24 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
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6EIV
 | | DYRK1A in complex with JWD-065 | | 分子名称: | Dual specificity tyrosine-phosphorylation-regulated kinase 1A, ~{N}-[3-[[4-azanyl-2-[[4-(4-methylpiperazin-1-yl)phenyl]amino]-1,3-thiazol-5-yl]carbonyl]phenyl]propanamide | | 著者 | Rothweiler, U. | | 登録日 | 2017-09-19 | | 公開日 | 2018-08-29 | | 最終更新日 | 2018-09-26 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Novel Scaffolds for Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase (DYRK1A) Inhibitors.
J. Med. Chem., 61, 2018
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