6ZMU
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![BU of 6zmu by Molmil](/molmil-images/mine/6zmu) | Crystal structure of the germline-specific thioredoxin protein Deadhead (Thioredoxin-1) from Drospohila melanogaster, P43212 | 分子名称: | SODIUM ION, SULFATE ION, Thioredoxin-1 | 著者 | Baginski, B, Pluta, R, Macias, M.J. | 登録日 | 2020-07-03 | 公開日 | 2020-10-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structures of the germline-specific Deadhead and thioredoxin T proteins from Drosophila melanogaster reveal unique features among thioredoxins. Iucrj, 8, 2021
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6ZMD
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![BU of 6zmd by Molmil](/molmil-images/mine/6zmd) | Crystal structure of HYPE covalently tethered to BiP bound to AMP-PNP | 分子名称: | Endoplasmic reticulum chaperone BiP, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Fauser, J, Gulen, B, Pett, C, Hedberg, C, Itzen, A, Pogenberg, V. | 登録日 | 2020-07-02 | 公開日 | 2021-04-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Specificity of AMPylation of the human chaperone BiP is mediated by TPR motifs of FICD. Nat Commun, 12, 2021
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6ZME
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![BU of 6zme by Molmil](/molmil-images/mine/6zme) | SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2020-07-02 | 公開日 | 2020-08-12 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
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7CGN
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![BU of 7cgn by Molmil](/molmil-images/mine/7cgn) | The overall structure of the MlaFEDB complex in ATP-bound EQtall conformation (Mutation of E170Q on MlaF) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, ... | 著者 | Chi, X.M, Fan, Q.X, Zhang, Y.Y, Liang, K, Zhou, Q, Li, Y.Y. | 登録日 | 2020-07-01 | 公開日 | 2020-09-09 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural mechanism of phospholipids translocation by MlaFEDB complex. Cell Res., 30, 2020
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7CGE
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![BU of 7cge by Molmil](/molmil-images/mine/7cge) | The overall structure of nucleotide free MlaFEDB complex | 分子名称: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, ... | 著者 | Chi, X.M, Fan, Q.X, Zhang, Y.Y, Liang, K, Zhou, Q, Li, Y.Y. | 登録日 | 2020-07-01 | 公開日 | 2020-09-09 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural mechanism of phospholipids translocation by MlaFEDB complex. Cell Res., 30, 2020
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7CGC
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7CGD
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![BU of 7cgd by Molmil](/molmil-images/mine/7cgd) | Silver-bound E.coli malate dehydrogenase | 分子名称: | Malate dehydrogenase, SILVER ION | 著者 | Wang, H, Wang, M, Sun, H. | 登録日 | 2020-07-01 | 公開日 | 2020-09-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Atomic differentiation of silver binding preference in protein targets: Escherichia coli malate dehydrogenase as a paradigm. Chem Sci, 11, 2020
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6XMN
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7CG3
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![BU of 7cg3 by Molmil](/molmil-images/mine/7cg3) | Staggered ring conformation of CtHsp104 (Hsp104 from Chaetomium Thermophilum) | 分子名称: | Heat shock protein 104 | 著者 | Inoue, Y, Hanazono, Y, Noi, K, Kawamoto, A, Kimatsuka, M, Harada, R, Takeda, K, Iwamasa, N, Shibata, K, Noguchi, K, Shigeta, Y, Namba, K, Ogura, T, Miki, K, Shinohara, K, Yohda, M. | 登録日 | 2020-06-30 | 公開日 | 2021-04-28 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (5.1 Å) | 主引用文献 | Split conformation of Chaetomium thermophilum Hsp104 disaggregase. Structure, 29, 2021
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7CGA
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6ZLI
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![BU of 6zli by Molmil](/molmil-images/mine/6zli) | CRYSTAL STRUCTURE OF KRAS-G12D IN COMPLEX WITH COMPOUND 13 AND GCP | 分子名称: | 2-[(2~{R})-piperidin-2-yl]-1~{H}-indole, GTPase KRas, MAGNESIUM ION, ... | 著者 | Kessler, D, Fischer, G, Boettcher, J. | 登録日 | 2020-06-30 | 公開日 | 2020-08-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Drugging all RAS isoforms with one pocket. Future Med Chem, 12, 2020
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6ZLN
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![BU of 6zln by Molmil](/molmil-images/mine/6zln) | CLK1 bound with GW807982X (Cpd 8) | 分子名称: | 1,2-ETHANEDIOL, 4-(6-ethoxypyrazolo[1,5-b]pyridazin-3-yl)-~{N}-[3-methoxy-5-(trifluoromethyl)phenyl]pyrimidin-2-amine, Dual specificity protein kinase CLK1 | 著者 | Schroeder, M, Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2020-06-30 | 公開日 | 2020-08-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | DFG-1 Residue Controls Inhibitor Binding Mode and Affinity, Providing a Basis for Rational Design of Kinase Inhibitor Selectivity. J.Med.Chem., 63, 2020
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6ZL5
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![BU of 6zl5 by Molmil](/molmil-images/mine/6zl5) | CRYSTAL STRUCTURE OF KRAS-G12D(C118S) IN COMPLEX WITH BI-2852 AND GDP | 分子名称: | (3~{S})-3-[2-[[[1-[(1-methylimidazol-4-yl)methyl]indol-6-yl]methylamino]methyl]-1~{H}-indol-3-yl]-5-oxidanyl-2,3-dihydroisoindol-1-one, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Kessler, D, Fischer, G, Boettcher, J. | 登録日 | 2020-06-30 | 公開日 | 2020-08-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.645 Å) | 主引用文献 | Drugging all RAS isoforms with one pocket. Future Med Chem, 12, 2020
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6ZL3
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![BU of 6zl3 by Molmil](/molmil-images/mine/6zl3) | CRYSTAL STRUCTURE OF HRAS IN COMPLEX WITH COMPOUND 18 and GDP | 分子名称: | (3~{S})-3-[2-[(dimethylamino)methyl]-1~{H}-indol-3-yl]-5-oxidanyl-2,3-dihydroisoindol-1-one, GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Kessler, D, Fischer, G, Boettcher, J. | 登録日 | 2020-06-30 | 公開日 | 2020-08-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.031 Å) | 主引用文献 | Drugging all RAS isoforms with one pocket. Future Med Chem, 12, 2020
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6XLW
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![BU of 6xlw by Molmil](/molmil-images/mine/6xlw) | Crystal structure of U2AF65 bound to AdML splice site sequence | 分子名称: | DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(P*UP*UP*(UD)P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), GLYCEROL, ... | 著者 | Maji, D, Jenkins, J.L, Kielkopf, C.L. | 登録日 | 2020-06-29 | 公開日 | 2020-10-07 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing. J.Biol.Chem., 295, 2020
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7CFW
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![BU of 7cfw by Molmil](/molmil-images/mine/7cfw) | Crystal structure of the receiver domain of sensor histidine kinase PA1611 (PA1611REC) from Pseudomonas aeruginosa PAO1 with calcium ion coordinated in the active site cleft | 分子名称: | CALCIUM ION, Histidine kinase | 著者 | Chen, S.K, Guan, H.H, Wu, P.H, Lin, L.T, Wu, M.C, Chang, H.Y, Chen, N.C, Lin, C.C, Chuankhayan, P, Huang, Y.C, Lin, P.J, Chen, C.J. | 登録日 | 2020-06-29 | 公開日 | 2020-11-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | 主引用文献 | Structural insights into the histidine-containing phospho-transfer protein and receiver domain of sensor histidine kinase suggest a complex model in the two-component regulatory system in Pseudomonas aeruginosa Iucrj, 7, 2020
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6XLX
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6XM2
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7CFZ
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6XLV
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6ZJN
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![BU of 6zjn by Molmil](/molmil-images/mine/6zjn) | Respiratory complex I from Thermus thermophilus, NADH dataset, minor state | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, NADH-quinone oxidoreductase subunit 1, ... | 著者 | Kaszuba, K, Tambalo, M, Gallagher, G.T, Sazanov, L.A. | 登録日 | 2020-06-29 | 公開日 | 2020-09-02 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | 主引用文献 | Key role of quinone in the mechanism of respiratory complex I. Nat Commun, 11, 2020
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6ZJL
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![BU of 6zjl by Molmil](/molmil-images/mine/6zjl) | Respiratory complex I from Thermus thermophilus, NAD+ dataset, major state | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ... | 著者 | Kaszuba, K, Tambalo, M, Gallagher, G.T, Sazanov, L.A. | 登録日 | 2020-06-29 | 公開日 | 2020-09-02 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Key role of quinone in the mechanism of respiratory complex I. Nat Commun, 11, 2020
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6ZJY
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![BU of 6zjy by Molmil](/molmil-images/mine/6zjy) | Respiratory complex I from Thermus thermophilus, NAD+ dataset, minor state | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, NADH-quinone oxidoreductase subunit 1, ... | 著者 | Kaszuba, K, Tambalo, M, Gallagher, G.T, Sazanov, L.A. | 登録日 | 2020-06-29 | 公開日 | 2020-09-02 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | 主引用文献 | Key role of quinone in the mechanism of respiratory complex I. Nat Commun, 11, 2020
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6ZJC
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![BU of 6zjc by Molmil](/molmil-images/mine/6zjc) | Crystal structure of Equus ferus caballus glutathione transferase A3-3 in complex with glutathione and triethyltin | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLUTATHIONE, Glutathione S-transferase, ... | 著者 | Skerlova, J, Ismail, A, Lindstrom, H, Sjodin, B, Mannervik, B, Stenmark, P. | 登録日 | 2020-06-28 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and functional analysis of the inhibition of equine glutathione transferase A3-3 by organotin endocrine disrupting pollutants. Environ Pollut, 268, 2021
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6ZJ9
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![BU of 6zj9 by Molmil](/molmil-images/mine/6zj9) | Crystal structure of Equus ferus caballus glutathione transferase A3-3 in complex with glutathione | 分子名称: | 1,2-ETHANEDIOL, GLUTATHIONE, Glutathione S-transferase | 著者 | Skerlova, J, Ismail, A, Lindstrom, H, Sjodin, B, Mannervik, B, Stenmark, P. | 登録日 | 2020-06-28 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and functional analysis of the inhibition of equine glutathione transferase A3-3 by organotin endocrine disrupting pollutants. Environ Pollut, 268, 2021
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