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6FJY
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Crystal structure of CsuC-CsuE chaperone-tip adhesion subunit pre-assembly complex from archaic chaperone-usher Csu pili of Acinetobacter baumannii
分子名称: CsuC, Protein CsuE
著者Pakharukova, N.A, Tuitilla, M, Paavilainen, S, Zavialov, A.V.
登録日2018-01-23
公開日2018-05-16
最終更新日2018-09-19
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural basis forAcinetobacter baumanniibiofilm formation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FPV
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BU of 6fpv by Molmil
A llama-derived JBP1-targeting nanobody
分子名称: GLYCEROL, Nanobody
著者van Beusekom, B, Adamopoulos, A, Heidebrecht, T, Joosten, R.P, Perrakis, A.
登録日2018-02-12
公開日2018-10-31
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Characterization and structure determination of a llama-derived nanobody targeting the J-base binding protein 1.
Acta Crystallogr F Struct Biol Commun, 74, 2018
1D1U
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BU of 1d1u by Molmil
USE OF AN N-TERMINAL FRAGMENT FROM MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE TO FACILITATE CRYSTALLIZATION AND ANALYSIS OF A PSEUDO-16-MER DNA MOLECULE CONTAINING G-A MISPAIRS
分子名称: DNA (5'-D(*AP*CP*GP*GP*CP*AP*CP*GP*AP*G)-3'), DNA (5'-D(*CP*TP*CP*GP*TP*G)-3'), PROTEIN (REVERSE TRANSCRIPTASE)
著者Cote, M.L, Yohannan, S, Georgiadis, M.M.
登録日1999-09-21
公開日2000-04-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Use of an N-terminal fragment from moloney murine leukemia virus reverse transcriptase to facilitate crystallization and analysis of a pseudo-16-mer DNA molecule containing G-A mispairs.
Acta Crystallogr.,Sect.D, 56, 2000
6FZR
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BU of 6fzr by Molmil
Crystal structure of scFv-SM3 in complex with compound 2
分子名称: 1,2-ETHANEDIOL, 2-deoxy-2-[(fluoroacetyl)amino]-alpha-D-galactopyranose, Mucin-1, ...
著者Bermejo, I.A, Usabiaga, I, Companon, I, Castro-Lopez, J, Insausti, A, Fernandez, J.A, Avenoza, A, Busto, J.H, Jimenez-Barbero, J, Asensio, J.L, Jimenez-Oses, G, Peregrina, J.M, Hurtado-Guerrero, R, Cocinero, E.J, Corzana, F.
登録日2018-03-15
公開日2019-02-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition.
J.Am.Chem.Soc., 140, 2018
3QJ3
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BU of 3qj3 by Molmil
Structure of digestive procathepsin L2 proteinase from Tenebrio molitor larval midgut
分子名称: ACETATE ION, Cathepsin L-like protein
著者Beton, D, Guzzo, C.R, Terra, W.R, Farah, C.S.
登録日2011-01-28
公開日2012-02-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The 3D structure and function of digestive cathepsin L-like proteinases of Tenebrio molitor larval midgut.
Insect Biochem.Mol.Biol., 42, 2012
5FF6
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BU of 5ff6 by Molmil
Cetuximab Fab in complex with L10Q meditope variant
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab heavy chain, Cetuximab Fab light chain, ...
著者Bzymek, K.P, Williams, J.C.
登録日2015-12-17
公開日2016-10-26
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
1CG2
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CARBOXYPEPTIDASE G2
分子名称: CARBOXYPEPTIDASE G2, ZINC ION
著者Rowsell, S, Pauptit, R.A, Tucker, A.D, Melton, R.G, Blow, D.M, Brick, P.
登録日1996-12-20
公開日1997-12-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of carboxypeptidase G2, a bacterial enzyme with applications in cancer therapy.
Structure, 5, 1997
5HVF
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Crystal Structure of Thrombin-activatable Fibrinolysis Inhibitor in Complex with an Inhibitory Nanobody (VHH-i83)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, Carboxypeptidase B2, ...
著者Zhou, X, Weeks, S.D, Strelkov, S.V, Declerck, P.J.
登録日2016-01-28
公開日2016-06-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Elucidation of the molecular mechanisms of two nanobodies that inhibit thrombin-activatable fibrinolysis inhibitor activation and activated thrombin-activatable fibrinolysis inhibitor activity.
J.Thromb.Haemost., 14, 2016
1DXZ
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BU of 1dxz by Molmil
M2 TRANSMEMBRANE SEGMENT OF ALPHA-SUBUNIT OF NICOTINIC ACETYLCHOLINE RECEPTOR FROM TORPEDO CALIFORNICA, NMR, 20 STRUCTURES
分子名称: ACETYLCHOLINE RECEPTOR PROTEIN, ALPHA CHAIN
著者Pashkov, V.S, Maslennikov, I.V, Tchikin, L.D, Efremov, R.G, Ivanov, V.T, Arseniev, A.S.
登録日2000-01-20
公開日2000-02-02
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Spatial Structure of the M2 Transmembrane Segment of the Nicotinic Acetylcholine Receptor Alpha-Subunit
FEBS Lett., 457, 1999
3RHU
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BU of 3rhu by Molmil
Epitope backbone grafting by computational design for improved presentation of linear epitopes on scaffold proteins
分子名称: SC_1wnu
著者Azoitei, M.L, Ban, Y.A, Julien, J.P, Bryson, S, Schroeter, A, Kalyuzhniy, O, Porter, J.R, Adachi, Y, Baker, D, Szabo, E, Pai, E.F, Schief, W.R.
登録日2011-04-12
公開日2011-11-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope.
J.Mol.Biol., 415, 2012
5EUK
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BU of 5euk by Molmil
Cetuximab Fab in complex with F3H meditope variant
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab heavy chain, Cetuximab Fab light chain, ...
著者Bzymek, K.P, Williams, J.C.
登録日2015-11-18
公開日2016-10-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72, 2016
3OZ9
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BU of 3oz9 by Molmil
Crystal Structure of anti-gp41 Fab NC-1
分子名称: Fab NC-1 IgG2a heavy chain, Fab NC-1 kappa light chain, GLYCEROL
著者Stanfield, R.L, Calarese, D.A, Jiang, S, Wilson, I.A.
登録日2010-09-24
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of anti-gp41 Fab NC-1
TO BE PUBLISHED
3OY8
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BU of 3oy8 by Molmil
Crystal structure of human galectin-1 in complex with lactobionic acid
分子名称: Galectin-1, beta-D-galactopyranose-(1-4)-D-gluconic acid
著者Blanchard, H, Collins, P.M.
登録日2010-09-23
公開日2010-11-03
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model
CANCER LETT., 2010
3OYW
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BU of 3oyw by Molmil
Crystal structure of human galectin-1 in complex with thiodigalactoside
分子名称: Galectin-1, beta-D-galactopyranose-(1-1)-1-thio-beta-D-galactopyranose
著者Blanchard, H, Collins, P.M.
登録日2010-09-23
公開日2010-11-03
最終更新日2020-08-12
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model
CANCER LETT., 2010
6H16
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BU of 6h16 by Molmil
Structure of LRP6 P3E3P4E4 in complex with VHH L-P2-D07
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Low-density lipoprotein receptor-related protein 6, ...
著者Gros, P, van Scherpenzeel, R.C.
登録日2018-07-11
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells.
Nat Commun, 10, 2019
6FZQ
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BU of 6fzq by Molmil
Crystal structure of scFv-SM3 in complex with compound 3
分子名称: 1,2-ETHANEDIOL, 2-deoxy-2-[(difluoroacetyl)amino]-alpha-D-galactopyranose, Mucin-1, ...
著者Bermejo, I.A, Usabiaga, I, Companon, I, Castro-Lopez, J, Insausti, A, Fernandez, J.A, Avenoza, A, Busto, J.H, Jimenez-Barbero, J, Asensio, J.L, Jimenez-Oses, G, Peregrina, J.M, Hurtado-Guerrero, R, Cocinero, E.J, Corzana, F.
登録日2018-03-15
公開日2019-02-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition.
J.Am.Chem.Soc., 140, 2018
1G84
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BU of 1g84 by Molmil
THE SOLUTION STRUCTURE OF THE C EPSILON2 DOMAIN FROM IGE
分子名称: IMMUNOGLOBULIN E
著者McDonnell, J.M, Cowburn, D, Gould, H.J, Sutton, B.J, Calvert, R, Beavil, R.E, Beavil, A.J, Henry, A.J.
登録日2000-11-16
公開日2001-05-16
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献The structure of the IgE Cepsilon2 domain and its role in stabilizing the complex with its high-affinity receptor FcepsilonRIalpha.
Nat.Struct.Biol., 8, 2001
5G5R
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BU of 5g5r by Molmil
CBS domain tandem of site-2 protease from Archaeoglobus fulgidus in complex with llama Nanobody - apo form
分子名称: NANOBODY, SITE-2 PROTEASE, SULFATE ION
著者Schacherl, M, Baumann, U.
登録日2016-06-02
公開日2017-05-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystallographic and biochemical characterization of the dimeric architecture of site-2 protease.
Biochim. Biophys. Acta, 1859, 2017
6GOL
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BU of 6gol by Molmil
Three dimensional structure of a novel influenza hemagglutinin tri-stalk protein
分子名称: Hemagglutinin tri-stalk
著者Kirsteina, A, Kazaks, A, Tars, K.
登録日2018-06-01
公開日2018-10-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and applications of novel influenza HA tri-stalk protein for evaluation of HA stem-specific immunity.
PLoS ONE, 13, 2018
3RFN
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BU of 3rfn by Molmil
Epitope backbone grafting by computational design for improved presentation of linear epitopes on scaffold proteins
分子名称: BB_1wnu_001, ZINC ION
著者Azoitei, M.L, Ban, Y.A, Julien, J.P, Bryson, S, Schroeter, A, Kalyuzhniy, O, Porter, J.R, Adachi, Y, Baker, D, Szabo, E, Pai, E.F, Schief, W.R.
登録日2011-04-06
公開日2011-11-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope.
J.Mol.Biol., 415, 2012
5FIA
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BU of 5fia by Molmil
Structure of the effector protein LpiR1 (Lpg0634) from Legionella pneumophila
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, LpiR1
著者Beyrakhova, K, van Straaten, K, Cygler, M.
登録日2015-12-22
公開日2016-01-27
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural and Functional Investigations of the Effector Protein LpiR1 from Legionella pneumophila.
J.Biol.Chem., 291, 2016
6FWW
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BU of 6fww by Molmil
GFP/KKK. A redesigned GFP with improved solubility
分子名称: Green fluorescent protein
著者Varejao, N, Lascorz, J, Gil-Garcia, M, Diaz-Caballero, M, Navarro, S, Ventura, S, Reverter, D.
登録日2018-03-07
公開日2018-08-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.131 Å)
主引用文献Combining Structural Aggregation Propensity and Stability Predictions To Redesign Protein Solubility.
Mol. Pharm., 15, 2018
3O6M
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BU of 3o6m by Molmil
Anti-Tat HIV 11H6H1 Fab' complexed with a 9-mer Tat peptide
分子名称: 11H6H1 Fab' heavy chain, 11H6H1 Fab' light chain, Protein Tat 9-mer peptide
著者Serriere, J, Gouet, P, Guillon, C.
登録日2010-07-29
公開日2010-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Fab'-induced folding of antigenic N-terminal peptides from intrinsically disordered HIV-1 Tat revealed by X-ray crystallography.
J.Mol.Biol., 405, 2011
6GCU
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MET receptor in complex with InlB internalin domain and DARPin A3A
分子名称: DARPin A3A, Hepatocyte growth factor receptor, Internalin B
著者Meyer, T, Andres, F, Iamele, L, Gherardi, E, Pluckthun, A, Niemann, H.H.
登録日2018-04-19
公開日2019-05-15
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (6.001 Å)
主引用文献Inhibition of the MET Kinase Activity and Cell Growth in MET-Addicted Cancer Cells by Bi-Paratopic Linking.
J.Mol.Biol., 431, 2019
5HVH
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BU of 5hvh by Molmil
Crystal Structure of Thrombin-activatable Fibrinolysis Inhibitor in Complex with two Inhibitory Nanobodies
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase B2, ...
著者Zhou, X, Weeks, S.D, Strelkov, S.V, Declerck, P.J.
登録日2016-01-28
公開日2016-06-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Elucidation of the molecular mechanisms of two nanobodies that inhibit thrombin-activatable fibrinolysis inhibitor activation and activated thrombin-activatable fibrinolysis inhibitor activity.
J.Thromb.Haemost., 14, 2016

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