6FJY
| Crystal structure of CsuC-CsuE chaperone-tip adhesion subunit pre-assembly complex from archaic chaperone-usher Csu pili of Acinetobacter baumannii | 分子名称: | CsuC, Protein CsuE | 著者 | Pakharukova, N.A, Tuitilla, M, Paavilainen, S, Zavialov, A.V. | 登録日 | 2018-01-23 | 公開日 | 2018-05-16 | 最終更新日 | 2018-09-19 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Structural basis forAcinetobacter baumanniibiofilm formation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6FPV
| A llama-derived JBP1-targeting nanobody | 分子名称: | GLYCEROL, Nanobody | 著者 | van Beusekom, B, Adamopoulos, A, Heidebrecht, T, Joosten, R.P, Perrakis, A. | 登録日 | 2018-02-12 | 公開日 | 2018-10-31 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Characterization and structure determination of a llama-derived nanobody targeting the J-base binding protein 1. Acta Crystallogr F Struct Biol Commun, 74, 2018
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1D1U
| USE OF AN N-TERMINAL FRAGMENT FROM MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE TO FACILITATE CRYSTALLIZATION AND ANALYSIS OF A PSEUDO-16-MER DNA MOLECULE CONTAINING G-A MISPAIRS | 分子名称: | DNA (5'-D(*AP*CP*GP*GP*CP*AP*CP*GP*AP*G)-3'), DNA (5'-D(*CP*TP*CP*GP*TP*G)-3'), PROTEIN (REVERSE TRANSCRIPTASE) | 著者 | Cote, M.L, Yohannan, S, Georgiadis, M.M. | 登録日 | 1999-09-21 | 公開日 | 2000-04-02 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Use of an N-terminal fragment from moloney murine leukemia virus reverse transcriptase to facilitate crystallization and analysis of a pseudo-16-mer DNA molecule containing G-A mispairs. Acta Crystallogr.,Sect.D, 56, 2000
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6FZR
| Crystal structure of scFv-SM3 in complex with compound 2 | 分子名称: | 1,2-ETHANEDIOL, 2-deoxy-2-[(fluoroacetyl)amino]-alpha-D-galactopyranose, Mucin-1, ... | 著者 | Bermejo, I.A, Usabiaga, I, Companon, I, Castro-Lopez, J, Insausti, A, Fernandez, J.A, Avenoza, A, Busto, J.H, Jimenez-Barbero, J, Asensio, J.L, Jimenez-Oses, G, Peregrina, J.M, Hurtado-Guerrero, R, Cocinero, E.J, Corzana, F. | 登録日 | 2018-03-15 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition. J.Am.Chem.Soc., 140, 2018
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3QJ3
| Structure of digestive procathepsin L2 proteinase from Tenebrio molitor larval midgut | 分子名称: | ACETATE ION, Cathepsin L-like protein | 著者 | Beton, D, Guzzo, C.R, Terra, W.R, Farah, C.S. | 登録日 | 2011-01-28 | 公開日 | 2012-02-01 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The 3D structure and function of digestive cathepsin L-like proteinases of Tenebrio molitor larval midgut. Insect Biochem.Mol.Biol., 42, 2012
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5FF6
| Cetuximab Fab in complex with L10Q meditope variant | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab heavy chain, Cetuximab Fab light chain, ... | 著者 | Bzymek, K.P, Williams, J.C. | 登録日 | 2015-12-17 | 公開日 | 2016-10-26 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes. Acta Crystallogr F Struct Biol Commun, 72, 2016
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1CG2
| CARBOXYPEPTIDASE G2 | 分子名称: | CARBOXYPEPTIDASE G2, ZINC ION | 著者 | Rowsell, S, Pauptit, R.A, Tucker, A.D, Melton, R.G, Blow, D.M, Brick, P. | 登録日 | 1996-12-20 | 公開日 | 1997-12-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of carboxypeptidase G2, a bacterial enzyme with applications in cancer therapy. Structure, 5, 1997
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5HVF
| Crystal Structure of Thrombin-activatable Fibrinolysis Inhibitor in Complex with an Inhibitory Nanobody (VHH-i83) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, Carboxypeptidase B2, ... | 著者 | Zhou, X, Weeks, S.D, Strelkov, S.V, Declerck, P.J. | 登録日 | 2016-01-28 | 公開日 | 2016-06-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Elucidation of the molecular mechanisms of two nanobodies that inhibit thrombin-activatable fibrinolysis inhibitor activation and activated thrombin-activatable fibrinolysis inhibitor activity. J.Thromb.Haemost., 14, 2016
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1DXZ
| M2 TRANSMEMBRANE SEGMENT OF ALPHA-SUBUNIT OF NICOTINIC ACETYLCHOLINE RECEPTOR FROM TORPEDO CALIFORNICA, NMR, 20 STRUCTURES | 分子名称: | ACETYLCHOLINE RECEPTOR PROTEIN, ALPHA CHAIN | 著者 | Pashkov, V.S, Maslennikov, I.V, Tchikin, L.D, Efremov, R.G, Ivanov, V.T, Arseniev, A.S. | 登録日 | 2000-01-20 | 公開日 | 2000-02-02 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Spatial Structure of the M2 Transmembrane Segment of the Nicotinic Acetylcholine Receptor Alpha-Subunit FEBS Lett., 457, 1999
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3RHU
| Epitope backbone grafting by computational design for improved presentation of linear epitopes on scaffold proteins | 分子名称: | SC_1wnu | 著者 | Azoitei, M.L, Ban, Y.A, Julien, J.P, Bryson, S, Schroeter, A, Kalyuzhniy, O, Porter, J.R, Adachi, Y, Baker, D, Szabo, E, Pai, E.F, Schief, W.R. | 登録日 | 2011-04-12 | 公開日 | 2011-11-09 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope. J.Mol.Biol., 415, 2012
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5EUK
| Cetuximab Fab in complex with F3H meditope variant | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab heavy chain, Cetuximab Fab light chain, ... | 著者 | Bzymek, K.P, Williams, J.C. | 登録日 | 2015-11-18 | 公開日 | 2016-10-26 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes. Acta Crystallogr F Struct Biol Commun, 72, 2016
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3OZ9
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3OY8
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3OYW
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6H16
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6FZQ
| Crystal structure of scFv-SM3 in complex with compound 3 | 分子名称: | 1,2-ETHANEDIOL, 2-deoxy-2-[(difluoroacetyl)amino]-alpha-D-galactopyranose, Mucin-1, ... | 著者 | Bermejo, I.A, Usabiaga, I, Companon, I, Castro-Lopez, J, Insausti, A, Fernandez, J.A, Avenoza, A, Busto, J.H, Jimenez-Barbero, J, Asensio, J.L, Jimenez-Oses, G, Peregrina, J.M, Hurtado-Guerrero, R, Cocinero, E.J, Corzana, F. | 登録日 | 2018-03-15 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition. J.Am.Chem.Soc., 140, 2018
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1G84
| THE SOLUTION STRUCTURE OF THE C EPSILON2 DOMAIN FROM IGE | 分子名称: | IMMUNOGLOBULIN E | 著者 | McDonnell, J.M, Cowburn, D, Gould, H.J, Sutton, B.J, Calvert, R, Beavil, R.E, Beavil, A.J, Henry, A.J. | 登録日 | 2000-11-16 | 公開日 | 2001-05-16 | 最終更新日 | 2021-10-27 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure of the IgE Cepsilon2 domain and its role in stabilizing the complex with its high-affinity receptor FcepsilonRIalpha. Nat.Struct.Biol., 8, 2001
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5G5R
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6GOL
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3RFN
| Epitope backbone grafting by computational design for improved presentation of linear epitopes on scaffold proteins | 分子名称: | BB_1wnu_001, ZINC ION | 著者 | Azoitei, M.L, Ban, Y.A, Julien, J.P, Bryson, S, Schroeter, A, Kalyuzhniy, O, Porter, J.R, Adachi, Y, Baker, D, Szabo, E, Pai, E.F, Schief, W.R. | 登録日 | 2011-04-06 | 公開日 | 2011-11-09 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope. J.Mol.Biol., 415, 2012
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5FIA
| Structure of the effector protein LpiR1 (Lpg0634) from Legionella pneumophila | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, LpiR1 | 著者 | Beyrakhova, K, van Straaten, K, Cygler, M. | 登録日 | 2015-12-22 | 公開日 | 2016-01-27 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural and Functional Investigations of the Effector Protein LpiR1 from Legionella pneumophila. J.Biol.Chem., 291, 2016
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6FWW
| GFP/KKK. A redesigned GFP with improved solubility | 分子名称: | Green fluorescent protein | 著者 | Varejao, N, Lascorz, J, Gil-Garcia, M, Diaz-Caballero, M, Navarro, S, Ventura, S, Reverter, D. | 登録日 | 2018-03-07 | 公開日 | 2018-08-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.131 Å) | 主引用文献 | Combining Structural Aggregation Propensity and Stability Predictions To Redesign Protein Solubility. Mol. Pharm., 15, 2018
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3O6M
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6GCU
| MET receptor in complex with InlB internalin domain and DARPin A3A | 分子名称: | DARPin A3A, Hepatocyte growth factor receptor, Internalin B | 著者 | Meyer, T, Andres, F, Iamele, L, Gherardi, E, Pluckthun, A, Niemann, H.H. | 登録日 | 2018-04-19 | 公開日 | 2019-05-15 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (6.001 Å) | 主引用文献 | Inhibition of the MET Kinase Activity and Cell Growth in MET-Addicted Cancer Cells by Bi-Paratopic Linking. J.Mol.Biol., 431, 2019
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5HVH
| Crystal Structure of Thrombin-activatable Fibrinolysis Inhibitor in Complex with two Inhibitory Nanobodies | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase B2, ... | 著者 | Zhou, X, Weeks, S.D, Strelkov, S.V, Declerck, P.J. | 登録日 | 2016-01-28 | 公開日 | 2016-06-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Elucidation of the molecular mechanisms of two nanobodies that inhibit thrombin-activatable fibrinolysis inhibitor activation and activated thrombin-activatable fibrinolysis inhibitor activity. J.Thromb.Haemost., 14, 2016
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