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2R0N
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The effect of a Glu370Asp mutation in Glutaryl-CoA Dehydrogenase on Proton Transfer to the Dienolate Intermediate
分子名称: 3-thiaglutaryl-CoA, FLAVIN-ADENINE DINUCLEOTIDE, Glutaryl-CoA dehydrogenase
著者Rao, K.S, Albro, M, Fu, Z, Narayanan, B, Baddam, S, Lee, H.J, Kim, J.J, Frerman, F.E.
登録日2007-08-20
公開日2008-04-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The effect of a Glu370Asp mutation in glutaryl-CoA dehydrogenase on proton transfer to the dienolate intermediate.
Biochemistry, 46, 2007
2R0M
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The effect of a Glu370Asp Mutation in Glutaryl-CoA Dehydrogenase on Proton Transfer to the Dienolate Intermediate
分子名称: 4-nitrobutanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Glutaryl-CoA dehydrogenase
著者Rao, K.S, Fu, Z, Albro, M, Narayanan, B, Baddam, S, Lee, H.J, Kim, J.J, Frerman, F.E.
登録日2007-08-20
公開日2008-04-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The effect of a Glu370Asp mutation in glutaryl-CoA dehydrogenase on proton transfer to the dienolate intermediate.
Biochemistry, 46, 2007
5I4N
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Crystal Structure of the E596A V617F Mutant JAK2 Pseudokinase Domain Bound to Mg-ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
著者Shiau, A.K, Motamedi, A.
登録日2016-02-12
公開日2016-04-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Uncoupling JAK2 V617F activation from cytokine-induced signalling by modulation of JH2 alpha C helix.
Biochem.J., 473, 2016
2NO5
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Crystal Structure analysis of a Dehalogenase with intermediate complex
分子名称: (2S)-2-CHLOROPROPANOIC ACID, (S)-2-haloacid dehalogenase IVA, CHLORIDE ION, ...
著者Schmidberger, J.W, Wilce, M.C.J.
登録日2006-10-24
公開日2007-09-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of the substrate free-enzyme, and reaction intermediate of the HAD superfamily member, haloacid dehalogenase DehIVa from Burkholderia cepacia MBA4
J.Mol.Biol., 368, 2007
3RTY
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BU of 3rty by Molmil
Structure of an Enclosed Dimer Formed by The Drosophila Period Protein
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Period circadian protein
著者King, H.A, Hoelz, A, Crane, B.R, Young, M.W.
登録日2011-05-04
公開日2011-12-21
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure of an enclosed dimer formed by the Drosophila period protein.
J.Mol.Biol., 413, 2011
3D1K
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BU of 3d1k by Molmil
R/T intermediate quaternary structure of an antarctic fish hemoglobin in an alpha(CO)-beta(pentacoordinate) state
分子名称: ACETYL GROUP, CARBON MONOXIDE, Hemoglobin subunit alpha-1, ...
著者Vitagliano, L, Vergara, A, Bonomi, G, Merlino, A, Mazzarella, L.
登録日2008-05-06
公開日2008-08-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Spectroscopic and crystallographic characterization of a tetrameric hemoglobin oxidation reveals structural features of the functional intermediate relaxed/tense state.
J.Am.Chem.Soc., 130, 2008
3O91
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High resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into catalytic mechanism and inhibition by aldehydes
分子名称: ZINC ION, nicotinamidase
著者French, J.B, Cen, Y, Sauve, A.A, Ealick, S.E.
登録日2010-08-03
公開日2011-01-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献High-resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into the catalytic mechanism and inhibition by aldehydes .
Biochemistry, 49, 2010
3O90
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High resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into catalytic mechanism and inhibition by aldehydes
分子名称: ZINC ION, nicotinamidase
著者French, J.B, Cen, Y, Sauve, A.A, Ealick, S.E.
登録日2010-08-03
公開日2011-01-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献High-resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into the catalytic mechanism and inhibition by aldehydes .
Biochemistry, 49, 2010
2P04
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2.1 Ang structure of the dimerized PAS domain of signal transduction histidine kinase from Nostoc punctiforme PCC 73102 with homology to the H-NOXA/H-NOBA domain of the soluble guanylyl cyclase
分子名称: signal transduction histidine kinase
著者van den Akker, F, Ma, X.
登録日2007-02-28
公開日2007-11-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献PAS-mediated dimerization of soluble guanylyl cyclase revealed by signal transduction histidine kinase domain crystal structure.
J.Biol.Chem., 283, 2008
3O92
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High resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into catalytic mechanism and inhibition by aldehydes
分子名称: ZINC ION, nicotinamidase
著者French, J.B, Cen, Y, Sauve, A.A, Ealick, S.E.
登録日2010-08-03
公開日2011-01-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献High-resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into the catalytic mechanism and inhibition by aldehydes .
Biochemistry, 49, 2010
3O94
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High resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into catalytic mechanism and inhibition by aldehydes
分子名称: NICOTINAMIDE, ZINC ION, nicotinamidase
著者French, J.B, Cen, Y, Sauve, A.A, Ealick, S.E.
登録日2010-08-03
公開日2011-01-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献High-resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into the catalytic mechanism and inhibition by aldehydes .
Biochemistry, 49, 2010
2OWW
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Covalent intermediate in amylomaltase in complex with the acceptor analog 4-deoxyglucose
分子名称: 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4-alpha-glucanotransferase, 4-deoxy-alpha-D-glucopyranose, ...
著者Barends, T.R.M, Bultema, J.B, Kaper, T, van der Maarel, M.J.E.C, Dijkhuizen, L, Dijkstra, B.W.
登録日2007-02-17
公開日2007-04-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Three-way stabilization of the covalent intermediate in amylomaltase, an alpha-amylase-like transglycosylase.
J.Biol.Chem., 282, 2007
2OWC
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Structure of a covalent intermediate in Thermus thermophilus amylomaltase
分子名称: 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4-alpha-glucanotransferase, GLYCEROL, ...
著者Barends, T.R.M, Bultema, J.B, Kaper, T, van der Maarel, M.J.E.C, Dijkhuizen, L, Dijkstra, B.W.
登録日2007-02-16
公開日2007-04-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Three-way stabilization of the covalent intermediate in amylomaltase, an alpha-amylase-like transglycosylase.
J.Biol.Chem., 282, 2007
2PQ9
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E. coli EPSPS liganded with (R)-difluoromethyl tetrahedral reaction intermediate analog
分子名称: (3R,4S,5R)-5-[(1R)-1-CARBOXY-2,2-DIFLUORO-1-(PHOSPHONOOXY)ETHOXY]-4-HYDROXY-3-(PHOSPHONOOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC ACID, 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID
著者Healy-Fried, M.L, Funke, T, Han, H, Schonbrunn, E.
登録日2007-05-01
公開日2008-03-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Differential inhibition of class I and class II 5-enolpyruvylshikimate-3-phosphate synthases by tetrahedral reaction intermediate analogues.
Biochemistry, 46, 2007
2ZCT
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Oxidation of archaeal peroxiredoxin involves a hypervalent sulfur intermediate
分子名称: Probable peroxiredoxin
著者Nakamura, T, Hagihara, Y, Abe, M, Inoue, T, Yamamoto, T, Matsumura, H.
登録日2007-11-12
公開日2008-05-27
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Oxidation of archaeal peroxiredoxin involves a hypervalent sulfur intermediate
Proc.Natl.Acad.Sci.Usa, 105, 2008
3O93
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High resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into catalytic mechanism and inhibition by aldehydes
分子名称: ZINC ION, nicotinamidase
著者French, J.B, Cen, Y, Sauve, A.A, Ealick, S.E.
登録日2010-08-03
公開日2011-01-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献High-resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into the catalytic mechanism and inhibition by aldehydes .
Biochemistry, 49, 2010
5TCU
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Methicillin sensitive Staphylococcus aureus 70S ribosome
分子名称: 16S RRNA, 23S RRNA, 30S ribosomal protein S10, ...
著者Eyal, Z, Ahmed, T, Belousoff, N, Mishra, S, Matzov, D, Bashan, A, Zimmerman, E, Lithgow, T, Bhushan, S, Yonath, A.
登録日2016-09-15
公開日2017-05-24
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome.
MBio, 8, 2017
2P08
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Structure of the N-terminally truncated PAS domain of signal transduction histidine kinase from Nostoc punctiforme PCC 73102 with homology to the H-NOXA/H-NOBA domain of the soluble guanylyl cyclase
分子名称: SULFATE ION, signal transduction histidine kinase
著者van den Akker, F, Ma, X.
登録日2007-02-28
公開日2007-11-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献PAS-mediated dimerization of soluble guanylyl cyclase revealed by signal transduction histidine kinase domain crystal structure.
J.Biol.Chem., 283, 2008
5RNT
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X-RAY ANALYSIS OF CUBIC CRYSTALS OF THE COMPLEX FORMED BETWEEN RIBONUCLEASE T1 AND GUANOSINE-3',5'-BISPHOSPHATE
分子名称: GUANOSINE-3',5'-DIPHOSPHATE, RIBONUCLEASE T1
著者Saenger, W, Heinemann, U, Lenz, A.
登録日1991-03-28
公開日1993-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献X-ray analysis of cubic crystals of the complex formed between ribonuclease T1 and guanosine-3',5'-bisphosphate.
Acta Crystallogr.,Sect.B, 47, 1991
2LBY
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G-quadruplex structure formed at the 5'-end of NHEIII_1 element in human c-MYC promoter
分子名称: DNA (5'-D(*TP*AP*GP*GP*GP*AP*GP*GP*GP*TP*AP*GP*GP*GP*AP*GP*GP*GP*T)-3')
著者Mathad, R, Hatzakis, E, Yang, D.
登録日2011-04-07
公開日2012-02-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献c-MYC promoter G-quadruplex formed at the 5'-end of NHE III1 element: insights into biological relevance and parallel-stranded G-quadruplex stability.
Nucleic Acids Res., 39, 2011
5DWX
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Structural Insights into the Quadruplex-Duplex 3' Interface formed from a Telomeric Repeat - TLOOP
分子名称: DNA (24-MER), DNA complementary strand, POTASSIUM ION
著者Parkinson, G.N, Russo Krauss, I.
登録日2015-09-23
公開日2016-01-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structural Insights into the Quadruplex-Duplex 3' Interface Formed from a Telomeric Repeat: A Potential Molecular Target.
J.Am.Chem.Soc., 138, 2016
2MY2
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Snu17p-Bud13p structure intermediate during RES complex assembly
分子名称: Pre-mRNA-splicing factor CWC26, U2 snRNP component IST3
著者Wysoczanski, P, Becker, S, Zweckstetter, M.
登録日2015-01-19
公開日2015-08-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structures of intermediates during RES complex assembly.
Sci Rep, 5, 2015
2DRW
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The crystal structutre of D-amino acid amidase from Ochrobactrum anthropi SV3
分子名称: BARIUM ION, D-Amino acid amidase
著者Okazaki, S, Suzuki, A, Komeda, H, Asano, Y, Yamane, T.
登録日2006-06-15
公開日2006-07-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure and Functional Characterization of a D-Stereospecific Amino Acid Amidase from Ochrobactrum anthropi SV3, a New Member of the Penicillin-recognizing Proteins
J.Mol.Biol., 368, 2007
2DNS
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The crystal structure of D-amino acid amidase from Ochrobactrum anthropi SV3 complexed with D-Phenylalanine
分子名称: BARIUM ION, D-PHENYLALANINE, D-amino acid amidase
著者Okazaki, S, Suzuki, A, Komeda, H, Asano, Y, Yamane, T.
登録日2006-04-26
公開日2006-05-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure and Functional Characterization of a D-Stereospecific Amino Acid Amidase from Ochrobactrum anthropi SV3, a New Member of the Penicillin-recognizing Proteins
J.Mol.Biol., 368, 2007
1FP2
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CRYSTAL STRUCTURE ANALYSIS OF ISOFLAVONE O-METHYLTRANSFERASE
分子名称: 4'-HYDROXY-7-METHOXYISOFLAVONE, ISOFLAVONE O-METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE
著者Zubieta, C, Dixon, R.A, Noel, J.P.
登録日2000-08-29
公開日2001-03-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structures of two natural product methyltransferases reveal the basis for substrate specificity in plant O-methyltransferases.
Nat.Struct.Biol., 8, 2001

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