2R0N

The effect of a Glu370Asp mutation in Glutaryl-CoA Dehydrogenase on Proton Transfer to the Dienolate Intermediate

Summary for 2R0N

• Entry DOI: 10.2210/pdb2r0n/pdb
• Related: 2R0M
• Descriptor: Glutaryl-CoA dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, 3-thiaglutaryl-CoA, ... (4 entities in total)
• Functional Keywords: glutaryl-coa dehydrogenase, flavoprotein, isomerase, alternative splicing, disease mutation, fad, mitochondrion, oxidoreductase, polymorphism, transit peptide
• Biological source: Homo sapiens (human)
• Cellular location: Mitochondrion matrix: Q92947
• Total number of polymer chains: 1
• Total formula weight: 45201.93

Authors

Rao, K.S.,Albro, M.,Fu, Z.,Narayanan, B.,Baddam, S.,Lee, H.J.,Kim, J.J.,Frerman, F.E. (deposition date: 2007-08-20, release date: 2008-04-22, Last modification date: 2023-08-30)

• Primary citation: Rao, K.S.,Fu, Z.,Albro, M.,Narayanan, B.,Baddam, S.,Lee, H.J.,Kim, J.J.,Frerman, F.E.; The effect of a Glu370Asp mutation in glutaryl-CoA dehydrogenase on proton transfer to the dienolate intermediate.; Biochemistry, 46:14468-14477, 2007; PubMed: 18020372; DOI: 10.1021/bi7009597

Experimental method

X-RAY DIFFRACTION (2.3 Å)