PDB: 17012 件ウェブページステータス検索Chemie searchBIRD

---

2FFL	Crystal Structure of Dicer from Giardia intestinalis 分子名称: Dicer, MANGANESE (II) ION 著者 Doudna, J.A, MacRae, I.J, Adams, P.D. 登録日 2005-12-19 公開日 2006-01-24 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.33 Å) 主引用文献 Structural Basis of Double-Stranded RNA Processing by Dicer Science, 311, 2006
4HLW	Targeting the Binding Function 3 (BF3) Site of the Human Androgen Receptor Through Virtual Screening. 2. Development of 2-((2-phenoxyethyl) thio)-1H-benzoimidazole derivatives. 分子名称: 2-[(2-phenoxyethyl)sulfanyl]-1H-benzimidazole, Androgen receptor, GLYCEROL, ... 著者 Ravi, S.N.M, Leblanc, E, Axerio-Cilies, P, Labriere, C, Frewin, K, Hassona, M.D.H, Lack, N.A, Han, F.Q, Guns, E.S, Young, R, Ban, F, Rennie, P.S, Cherkasov, A. 登録日 2012-10-17 公開日 2013-01-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Targeting the Binding Function 3 (BF3) Site of the Androgen Receptor Through Virtual Screening. 2. Development of 2-((2-phenoxyethyl) thio)-1H-benzimidazole Derivatives. J.Med.Chem., 56, 2013
4MGS	BiXyn10A CBM1 APO 分子名称: Putative glycosyl hydrolase family 10 著者 Chekan, J.R, Nair, S.K. 登録日 2013-08-28 公開日 2014-08-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Xylan utilization in human gut commensal bacteria is orchestrated by unique modular organization of polysaccharide-degrading enzymes. Proc.Natl.Acad.Sci.USA, 111, 2014
3PF3	Crystal structure of a mutant (C202A) of Triosephosphate isomerase from Giardia lamblia derivatized with MMTS 分子名称: CALCIUM ION, GLYCEROL, SULFATE ION, ... 著者 Enriquez-Flores, S, Rodriguez-Romero, A, Hernandez-Santoyo, A, Reyes-Vivas, H. 登録日 2010-10-27 公開日 2011-06-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.098 Å) 主引用文献 Determining the molecular mechanism of inactivation by chemical modification of triosephosphate isomerase from the human parasite Giardia lamblia: A study for antiparasitic drug design. Proteins, 79, 2011
4EVH	Crystal structure of calcium-bound alpha-1 giardin 分子名称: CALCIUM ION, Giardin subunit alpha-1 著者 Weeratunga, S, Hofmann, A. 登録日 2012-04-26 公開日 2012-07-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Alpha-1 giardin is an annexin with highly unusual calcium-regulated mechanisms J.Mol.Biol., 423, 2012
4QPW	BiXyn10A CBM1 with Xylohexaose Bound 分子名称: beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, glycosyl hydrolase family 10 著者 Chekan, J.R, Nair, S.K. 登録日 2014-06-25 公開日 2014-08-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.14 Å) 主引用文献 Xylan utilization in human gut commensal bacteria is orchestrated by unique modular organization of polysaccharide-degrading enzymes. Proc.Natl.Acad.Sci.USA, 111, 2014
4EVF	Crystal structure of apo alpha-1 giardin 分子名称: Giardin subunit alpha-1 著者 Weeratunga, S, Hofmann, A. 登録日 2012-04-26 公開日 2012-07-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Alpha-1 giardin is an annexin with highly unusual calcium-regulated mechanisms J.Mol.Biol., 423, 2012
4RJY	Crystal structure of E. coli L-Threonine Aldolase in complex with a non-covalently uncleaved bound L-serine substrate 分子名称: Low specificity L-threonine aldolase, SERINE, SODIUM ION 著者 Safo, M.K, Chowdhury, N, Gandhi, A.K. 登録日 2014-10-11 公開日 2014-10-29 最終更新日 2015-02-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Molecular basis of E. colil-threonine aldolase catalytic inactivation at low pH. Biochim.Biophys.Acta, 1854, 2015
5KYA	Brain penetrant liver X receptor (LXR) modulators based on a 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole core 分子名称: Oxysterols receptor LXR-beta, Retinoic acid receptor RXR-beta, [2-[(6~{R})-2-(3-methylsulfonylphenyl)-6-propan-2-yl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-4-(trifluoromethyl)pyrimidin-5-yl]methanol 著者 Chen, G, McKeever, B.M. 登録日 2016-07-21 公開日 2016-09-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.598 Å) 主引用文献 Brain penetrant liver X receptor (LXR) modulators based on a 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole core. Bioorg.Med.Chem.Lett., 26, 2016
5LDY	Structure of Yersinia pseudotuberculosis InvD 分子名称: Ig domain protein group 1 domain protein, PHOSPHATE ION 著者 Sadana, P, Scrima, A. 登録日 2016-06-28 公開日 2017-06-14 最終更新日 2020-06-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The invasin D protein from Yersinia pseudotuberculosis selectively binds the Fab region of host antibodies and affects colonization of the intestine J.Biol.Chem., 2018
2GSA	CRYSTAL STRUCTURE OF GLUTAMATE-1-SEMIALDEHYDE AMINOMUTASE (AMINOTRANSFERASE, WILD-TYPE FORM) 分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, GLUTAMATE SEMIALDEHYDE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE 著者 Hennig, M, Jansonius, J.N. 登録日 1997-02-26 公開日 1998-03-04 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of glutamate-1-semialdehyde aminomutase: an alpha2-dimeric vitamin B6-dependent enzyme with asymmetry in structure and active site reactivity. Proc.Natl.Acad.Sci.USA, 94, 1997
5DEF	Crystal structure of B*27:04 complex bound to the pVIPR peptide 分子名称: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ... 著者 Loll, B, Fabian, H, Huser, H, Hee, C.S, Uchanska-Ziegler, B, Ziegler, A. 登録日 2015-08-25 公開日 2015-11-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Increased Conformational Flexibility of HLA-B*27 Subtypes Associated With Ankylosing Spondylitis. Arthritis Rheumatol, 68, 2016
4APN	Structure of TR from Leishmania infantum in complex with a diarylpirrole-based inhibitor 分子名称: 4-[[1-(4-ethylphenyl)-2-methyl-5-(4-methylsulfanylphenyl)pyrrol-3-yl]methyl]thiomorpholine, FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Baiocco, P, Ilari, A, Colotti, G, Biava, M. 登録日 2012-04-04 公開日 2013-04-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Inhibition of Leishmania Infantum Trypanothione Reductase by Azole-Based Compounds: A Comparative Analysis with its Physiological Substrate by X-Ray Crystallography. Chemmedchem, 8, 2013
5DEG	Crystal structure of B*27:06 bound to the pVIPR peptide 分子名称: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... 著者 Loll, B, Fabian, H, Hee, C.S, Huser, H, Uchanska-Ziegler, B, Ziegler, A. 登録日 2015-08-25 公開日 2015-11-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Increased Conformational Flexibility of HLA-B*27 Subtypes Associated With Ankylosing Spondylitis. Arthritis Rheumatol, 68, 2016
5LS9	Humanized Archaeal ferritin 分子名称: Ferritin, putative, MAGNESIUM ION 著者 Baiocco, P, Trabuco, M.C, Boffi, A. 登録日 2016-08-23 公開日 2016-11-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.93 Å) 主引用文献 Humanized archaeal ferritin as a tool for cell targeted delivery. Nanoscale, 9, 2017
5O3I	Human Brd2(BD2) mutant in complex with AL-tBu 分子名称: (2~{S})-1-[(2~{S})-2-oxidanylpropoxy]propan-2-ol, Bromodomain-containing protein 2, CHLORIDE ION, ... 著者 Chan, K.-H, Runcie, A.C, Ciulli, A. 登録日 2017-05-23 公開日 2018-02-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Optimization of a "bump-and-hole" approach to allele-selective BET bromodomain inhibition. Chem Sci, 9, 2018
4GSA	CRYSTAL STRUCTURE OF GLUTAMATE-1-SEMIALDEHYDE AMINOMUTASE (AMINOTRANSFERASE) REDUCED WITH CYANOBOROHYDRATE 分子名称: GLUTAMATE SEMIALDEHYDE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE 著者 Hennig, M, Jansonius, J.N. 登録日 1997-02-26 公開日 1998-03-04 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of glutamate-1-semialdehyde aminomutase: an alpha2-dimeric vitamin B6-dependent enzyme with asymmetry in structure and active site reactivity. Proc.Natl.Acad.Sci.USA, 94, 1997
4LNL	Structure of Escherichia coli Threonine Aldolase in Complex with Allo-Thr 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Low-specificity L-threonine aldolase, ... 著者 Safo, M.K. 登録日 2013-07-11 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 On the catalytic mechanism and stereospecificity of Escherichia coli l-threonine aldolase. Febs J., 281, 2014
3N45	Human FPPS complex with FBS_04 and zoledronic acid/MG2+ 分子名称: (2S)-1-[(benzyloxy)carbonyl]-2,3-dihydro-1H-indole-2-carboxylic acid, FARNESYL PYROPHOSPHATE SYNTHASE, MAGNESIUM ION, ... 著者 Rondeau, J.-M. 登録日 2010-05-21 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3N5H	Human fpps complex with NOV_304 分子名称: 3-(carboxymethyl)-4,7-dichloro-1H-indole-2-carboxylic acid, FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION 著者 Rondeau, J.-M. 登録日 2010-05-25 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3N6K	Human FPPS complex with NOV_823 分子名称: 1-(carboxymethyl)-1H-benzo[g]indole-2-carboxylic acid, FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION 著者 Rondeau, J.-M. 登録日 2010-05-26 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3N5J	Human fpps complex with NOV_311 分子名称: 3-(carboxymethyl)-5,7-dichloro-1H-indole-2-carboxylic acid, FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION 著者 Rondeau, J.-M. 登録日 2010-05-25 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3N1V	Human FPPS COMPLEX WITH FBS_01 分子名称: (5-chloro-3-methyl-1-benzothiophen-2-yl)acetic acid, FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION 著者 Rondeau, J.-M. 登録日 2010-05-17 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3N49	Human FPPS COMPLEX WITH NOV_292 分子名称: FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION, naphtho[2,1-b]thiophen-1-ylacetic acid 著者 Rondeau, J.-M. 登録日 2010-05-21 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3N3L	Human FPPS complex with FBS_03 分子名称: (6-methoxy-1-benzofuran-3-yl)acetic acid, FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION 著者 Rondeau, J.-M. 登録日 2010-05-20 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010

<27282930313233343536373839404142>