PDB: 37044 件ウェブページステータス検索Chemie searchBIRD

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1YHV	Crystal Structure of PAK1 kinase domain with two point mutations (K299R, T423E) 分子名称: Serine/threonine-protein kinase PAK 1 著者 Lei, M, Robinson, M.A, Harrison, S.C. 登録日 2005-01-10 公開日 2005-05-24 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Active Conformation of the PAK1 Kinase Domain Structure, 13, 2005
1YI3	Crystal Structure of Pim-1 bound to LY294002 分子名称: 2-MORPHOLIN-4-YL-7-PHENYL-4H-CHROMEN-4-ONE, Proto-oncogene serine/threonine-protein kinase Pim-1 著者 Jacobs, M.D, Black, J, Futer, O, Swenson, L, Hare, B, Fleming, M, Saxena, K. 登録日 2005-01-11 公開日 2005-01-25 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Pim-1 ligand-bound structures reveal the mechanism of serine/threonine kinase inhibition by LY294002. J.Biol.Chem., 280, 2005
6CSW	Crystal Structure of the Human vaccinia-related kinase bound to a N-methyl-N-propyl-dihydropteridine inhibitor 分子名称: (7R)-5-butyl-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7,8-dimethyl-7,8-dihydropteridin-6(5H)-one, ACETATE ION, CHLORIDE ION, ... 著者 dos Reis, C.V, de Souza, G.P, Counago, R.M, Chiodi, C.G, Azevedo, A, Guimaraes, C, Mascarello, A, Gama, F, Ferreira, M, Massirer, K.B, Arruda, P, Edwards, A.M, Elkins, J.M, Structural Genomics Consortium (SGC) 登録日 2018-03-21 公開日 2018-04-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of the Human vaccinia-related kinase bound to a N-methyl-N-propyl-dihydropteridine inhibitor To Be Published
1Y09	T-to-T(High) Quaternary Transitions in Human Hemoglobin: alphaN97A deoxy low-salt 分子名称: Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE 著者 Kavanaugh, J.S, Rogers, P.H, Arnone, A. 登録日 2004-11-15 公開日 2004-11-30 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions. Biochemistry, 44, 2005
1Y0M	Crystal structure of of the SH3 domain of phospholipase C Gamma-1 分子名称: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 著者 Mariuzza, R, Sangwoo, C. 登録日 2004-11-15 公開日 2006-02-21 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Crystal structure of of the SH3 domain of phospholipase C Gamma-1 To be Published
1Y4F	T-To-T(High) quaternary transitions in human hemoglobin: betaW37A deoxy low-salt (10 test sets) 分子名称: Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE 著者 Kavanaugh, J.S, Rogers, P.H, Arnone, A. 登録日 2004-11-30 公開日 2004-12-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions. Biochemistry, 44, 2005
1Y4V	T-To-T(High) quaternary transitions in human hemoglobin: betaC93A deoxy low-salt (1 test set) 分子名称: Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE 著者 Kavanaugh, J.S, Rogers, P.H, Arnone, A. 登録日 2004-12-01 公開日 2004-12-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions. Biochemistry, 44, 2005
7STZ	Crystal Structure of Human E-cadherin EC1-5 bound by mouse monoclonal antibody Fab mAb-1_19A11 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-11-15 公開日 2022-01-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Regulation of multiple dimeric states of E-cadherin by adhesion activating antibodies revealed through Cryo-EM and X-ray crystallography. Pnas Nexus, 1, 2022
1Y7C	T-To-T(High) quaternary transitions in human hemoglobin: betaP100A deoxy low-salt (1 test set) 分子名称: Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE 著者 Kavanaugh, J.S, Rogers, P.H, Arnone, A. 登録日 2004-12-08 公開日 2004-12-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions. Biochemistry, 44, 2005
1Y85	T-To-T(High) quaternary transitions in human hemoglobin: desHIS146beta deoxy low-salt 分子名称: Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE 著者 Kavanaugh, J.S, Rogers, P.H, Arnone, A. 登録日 2004-12-10 公開日 2004-12-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions. Biochemistry, 44, 2005
1Y8K	Horse methemoglobin low salt, PH 7.0 (88% relative humidity) 分子名称: Hemoglobin alpha chains, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE 著者 Sankaranarayanan, R, Biswal, B.K, Vijayan, M. 登録日 2004-12-13 公開日 2005-07-26 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A new relaxed state in horse methemoglobin characterized by crystallographic studies. Proteins, 60, 2005
6CR2	Crystal structure of sterol 14-alpha demethylase (CYP51B) from Aspergillus fumigatus in complex with the VNI derivative N-(1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethyl)-4-(5-(2-fluoro-4-(2,2,2-trifluoroethoxy)phenyl)-1,3,4-oxadiazol-2-yl)benzamide 分子名称: 14-alpha sterol demethylase Cyp51B, N-[(1R)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethyl]-4-{5-[2-fluoro-4-(2,2,2-trifluoroethoxy)phenyl]-1,3,4-oxadiazol-2-yl}benzamide, PROTOPORPHYRIN IX CONTAINING FE 著者 Friggeri, L, Hargrove, T.Y, Wawrzak, Z, Lepesheva, G.I. 登録日 2018-03-16 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Sterol 14 alpha-Demethylase Structure-Based Design of VNI (( R)- N-(1-(2,4-Dichlorophenyl)-2-(1 H-imidazol-1-yl)ethyl)-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide)) Derivatives To Target Fungal Infections: Synthesis, Biological Evaluation, and Crystallographic Analysis. J. Med. Chem., 61, 2018
1Y45	T-To-T(high) quaternary transitions in human hemoglobin: betaP36A deoxy low-salt (10 test sets) 分子名称: Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE 著者 Kavanaugh, J.S, Rogers, P.H, Arnone, A. 登録日 2004-11-30 公開日 2004-12-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions. Biochemistry, 44, 2005
1Y4P	T-To-T(high) quaternary transitions in human hemoglobin: betaW37E deoxy low-salt (10 test sets) 分子名称: Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE 著者 Kavanaugh, J.S, Rogers, P.H, Arnone, A. 登録日 2004-12-01 公開日 2004-12-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions. Biochemistry, 44, 2005
7STA	X-ray Crystal Structure of Truncated Human Chemokine CCL19 (7-70) 分子名称: C-C motif chemokine 19 著者 Lewandowski, E.M, Kroeck, K, Chen, Y. 登録日 2021-11-12 公開日 2022-02-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Insights into Molecular Recognition by Human Chemokine CCL19. Biochemistry, 61, 2022
6CUN	Engineered Cytochrome c from Rhodothermus marinus (Rma TDE) bound to carbene intermediate (1-ethoxy-1-oxopropan-2-ylidene) 分子名称: Cytochrome c, ETHYL PROPIONATE, HEME C 著者 Lewis, R.D, Buller, A.R, Arnold, F.H. 登録日 2018-03-26 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 Catalytic iron-carbene intermediate revealed in a cytochromeccarbene transferase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1Y8W	T-To-T(High) quaternary transitions in human hemoglobin: alphaR92A oxy (2mM IHP, 20% PEG) (10 test sets) 分子名称: Hemoglobin alpha chain, Hemoglobin beta chain, OXYGEN MOLECULE, ... 著者 Kavanaugh, J.S, Rogers, P.H, Arnone, A. 登録日 2004-12-13 公開日 2005-01-04 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions. Biochemistry, 44, 2005
1Y94	Crystal structure of the G16S/N17T/P19A/S20A/N67D Variant Of Bovine seminal Ribonuclease 分子名称: Seminal ribonuclease 著者 Picone, D, Di Fiore, A, Ercole, C, Franzese, M, Sica, F, Tomaselli, S, Mazzarella, L. 登録日 2004-12-14 公開日 2004-12-28 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Role of the Hinge Loop in Domain Swapping: THE SPECIAL CASE OF BOVINE SEMINAL RIBONUCLEASE. J.Biol.Chem., 280, 2005
1YI4	Structure of Pim-1 bound to adenosine 分子名称: ADENOSINE, Proto-oncogene serine/threonine-protein kinase Pim-1 著者 Jacobs, M.D, Black, J, Futer, O, Swenson, L, Hare, B, Fleming, M, Saxena, K. 登録日 2005-01-11 公開日 2005-01-25 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Pim-1 ligand-bound structures reveal the mechanism of serine/threonine kinase inhibition by LY294002. J.Biol.Chem., 280, 2005
1Y0A	T-to-THigh Quaternary Transitions in Human Hemoglobin: alphaY140A deoxy low-salt 分子名称: Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE 著者 Kavanaugh, J.S, Rogers, P.H, Arnone, A. 登録日 2004-11-15 公開日 2004-12-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions. Biochemistry, 44, 2005
1YF4	Crystal Structure of trypsin-vasopressin complex 分子名称: CALCIUM ION, Trypsin, Vasopressin 著者 Syed Ibrahim, B, Pattabhi, V. 登録日 2004-12-30 公開日 2005-05-24 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Trypsin inhibition by a Peptide hormone: crystal structure of trypsin-vasopressin complex J.Mol.Biol., 348, 2005
1YGF	T-to-T(high) quaternary transitions in human hemoglobin: betaH97A oxy (2MM IHP, 20% PEG) (1 test set) 分子名称: Hemoglobin alpha chain, Hemoglobin beta chain, OXYGEN MOLECULE, ... 著者 Kavanaugh, J.S, Rogers, P.H, Arnone, A. 登録日 2005-01-04 公開日 2005-01-11 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions. Biochemistry, 44, 2005
6CPF	Structure of dephosphorylated Aurora A (122-403) bound to AMPPCP in an active conformation 分子名称: Aurora kinase A, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER 著者 Otten, R, Zorba, A, Padua, R.A.P, Kern, D. 登録日 2018-03-13 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Dynamics of human protein kinase Aurora A linked to drug selectivity. Elife, 7, 2018
1Y3W	TRYPSIN INHIBITOR COMPLEX 分子名称: (1R,3AS,4R,8AS,8BR)-4-(2-BENZO[1,3]DIOXOL-5-YLMETHYL-1-ETHYL-3-OXO-DECAHYDRO-PYRROLO[3,4-A]PYRROLIZIN-4-YL)-BENZAMIDINE, CALCIUM ION, Trypsinogen, ... 著者 Fokkens, J, Klebe, G. 登録日 2004-11-26 公開日 2005-12-06 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A simple protocol to estimate differences in protein binding affinity for enantiomers without prior resolution of racemates. Angew.Chem.Int.Ed.Engl., 45, 2006
1Y46	T-To-T(High) quaternary transitions in human hemoglobin: betaW37Y deoxy low-salt (10 test sets) 分子名称: Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE 著者 Kavanaugh, J.S, Rogers, P.H, Arnone, A. 登録日 2004-11-30 公開日 2004-12-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions. Biochemistry, 44, 2005

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