7A18
 
 | | 50S Deinococcus radiodurans ribosome bounded with mycinamicin IV | | 分子名称: | 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L15, ... | | 著者 | Breiner, E, Eyal, Z, Matzov, D, Halfon, Y, Cimicata, G, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A. | | 登録日 | 2020-08-12 | | 公開日 | 2021-10-06 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida.
Nucleic Acids Res., 49, 2021
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7NJU
 | | Mycobacterium smegmatis ATP synthase Fo combined class 1 | | 分子名称: | ATP synthase subunit a, ATP synthase subunit b, ATP synthase subunit b-delta, ... | | 著者 | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | 登録日 | 2021-02-17 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | | 主引用文献 | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJV
 | | Mycobacterium smegmatis ATP synthase Fo combined class 2 | | 分子名称: | ATP synthase subunit a, ATP synthase subunit b, ATP synthase subunit b-delta, ... | | 著者 | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | 登録日 | 2021-02-17 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NKN
 | | Mycobacterium smegmatis ATP synthase rotor state 3 | | 分子名称: | ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit alpha, ... | | 著者 | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | 登録日 | 2021-02-18 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | | 主引用文献 | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJX
 | | Mycobacterium smegmatis ATP synthase Fo combined class 4 | | 分子名称: | ATP synthase subunit a, ATP synthase subunit b, ATP synthase subunit b-delta, ... | | 著者 | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | 登録日 | 2021-02-17 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (4.32 Å) | | 主引用文献 | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJY
 | | Mycobacterium smegmatis ATP synthase Fo combined class 5 | | 分子名称: | ATP synthase subunit a, ATP synthase subunit b, ATP synthase subunit b-delta, ... | | 著者 | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | 登録日 | 2021-02-17 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | | 主引用文献 | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6P58
 | | Dark and Steady State-Illuminated Crystal Structure of Cyanobacteriochrome Receptor PixJ at 150K | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, Methyl-accepting chemotaxis protein, ... | | 著者 | Clinger, J.A, Miller, M.D, Buirgie, E.S, Vierstra, R.D, Phillips Jr, G.N. | | 登録日 | 2019-05-29 | | 公開日 | 2019-12-18 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.499 Å) | | 主引用文献 | Photoreversible interconversion of a phytochrome photosensory module in the crystalline state.
Proc.Natl.Acad.Sci.USA, 117, 2020
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7NKP
 | | Mycobacterium smegmatis ATP synthase Fo state 2 | | 分子名称: | ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit a, ... | | 著者 | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | 登録日 | 2021-02-18 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (4.06 Å) | | 主引用文献 | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NKK
 | | Mycobacterium smegmatis ATP synthase rotor state 2 | | 分子名称: | ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit alpha, ... | | 著者 | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | 登録日 | 2021-02-18 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NL9
 | | Mycobacterium smegmatis ATP synthase Fo state 3 | | 分子名称: | ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit a, ... | | 著者 | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | 登録日 | 2021-02-22 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | | 主引用文献 | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NJT
 | | Mycobacterium smegmatis ATP synthase Fo combined all classes | | 分子名称: | ATP synthase subunit a, ATP synthase subunit b, ATP synthase subunit b-delta, ... | | 著者 | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | 登録日 | 2021-02-17 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NKB
 | | Mycobacterium smegmatis ATP synthase rotor state 1 | | 分子名称: | ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit alpha, ... | | 著者 | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | 登録日 | 2021-02-17 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7NK9
 | | Mycobacterium smegmatis ATP synthase Fo domain state 1 | | 分子名称: | ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit a, ... | | 著者 | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | | 登録日 | 2021-02-17 | | 公開日 | 2021-11-03 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7YWL
 | | Six DNA Helix Bundle nanopore - State 3 | | 分子名称: | DNA (50-MER) | | 著者 | Javed, A, Ahmad, K, Lanphere, C, Coveney, P, Howorka, S, Orlova, E.V. | | 登録日 | 2022-02-14 | | 公開日 | 2023-05-24 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (8 Å) | | 主引用文献 | Structure and dynamics of an archetypal DNA nanoarchitecture revealed via cryo-EM and molecular dynamics simulations.
Nat Commun, 14, 2023
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7Q41
 | | Crystal structure of RCC1-Like domain 2 of ubiquitin ligase HERC2 in complex with DXDKDED motif of ubiquitin-protein ligase E3A (E6AP) | | 分子名称: | CITRIC ACID, E3 ubiquitin-protein ligase HERC2, Ubiquitin-protein ligase E3A (E6AP) peptide | | 著者 | Demenge, A, Howard, E, Cousido-Siah, A, Mitschler, A, Podjarny, A, McEwen, A.G, Trave, G. | | 登録日 | 2021-10-29 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.01478052 Å) | | 主引用文献 | Crystal structure of RCC1-Like domain 2 of ubiquitin ligase HERC2 in complex with DXDKDED motif of ubiquitin-protein ligase E3A (E6AP)
To Be Published
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7Q45
 | | Crystal structure of RCC1-Like domain 2 of ubiquitin ligase HERC2 in complex with DXDKDED motif of Myelin transcription factor 1 | | 分子名称: | CITRIC ACID, E3 ubiquitin-protein ligase HERC2, Myelin transcription factor 1 | | 著者 | Demenge, A, Howard, E, Cousido-Siah, A, Mitschler, A, Podjarny, A, McEwen, A.G, Trave, G. | | 登録日 | 2021-10-29 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.09999585 Å) | | 主引用文献 | Crystal structure of RCC1-Like domain 2 of ubiquitin ligase HERC2 in complex with DXDKDED motif of Myelin transcription factor 1
To Be Published
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8C5V
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6OYU
 | | Structure of an ancestral-reconstructed cytochrome P450 1B1 with alpha-naphthoflavone | | 分子名称: | 2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE, Cytochrome P450 1B1, GLYCEROL, ... | | 著者 | Bart, A.G, Harris, K.L, Scott, E.E. | | 登録日 | 2019-05-15 | | 公開日 | 2020-03-18 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structure of an ancestral mammalian family 1B1 cytochrome P450 with increased thermostability.
J.Biol.Chem., 295, 2020
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8TTM
 | | IgG1 Fc Heterodimer combYSelect1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin gamma-1 heavy chain | | 著者 | Azzam, T, Du, J.J, Sundberg, E.J. | | 登録日 | 2023-08-14 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Combinatorially restricted computational design of protein-protein interfaces to produce IgG heterodimers.
Sci Adv, 10, 2024
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8EK5
 | | Engineered scFv 10LH bound to PHOX2B/HLA-A24:02 | | 分子名称: | 10LH single chain fragment variable (scFv), Beta-2-microglobulin, GLYCEROL, ... | | 著者 | Garfinkle, S.E, Florio, T.J, Sgourakis, N.G. | | 登録日 | 2022-09-20 | | 公開日 | 2023-12-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion.
Sci Immunol, 8, 2023
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8TUD
 | | IgG1 Fc Heterodimer combYSelect2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin gamma-1 heavy chain | | 著者 | Azzam, T, Du, J.J, Sundberg, E.J. | | 登録日 | 2023-08-16 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Combinatorially restricted computational design of protein-protein interfaces to produce IgG heterodimers.
Sci Adv, 10, 2024
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6P07
 | | Spastin hexamer in complex with substrate | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Sandate, C.R, Szyk, A, Zehr, E, Roll-Mecak, A, Lander, G.C. | | 登録日 | 2019-05-16 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | An allosteric network in spastin couples multiple activities required for microtubule severing.
Nat.Struct.Mol.Biol., 26, 2019
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7AQJ
 | | Structure of SARS-CoV-2 Main Protease bound to Triglycidyl isocyanurate. | | 分子名称: | 1-[(2~{R})-2-oxidanylpropyl]-3-[[(2~{R})-oxiran-2-yl]methyl]-5-[[(2~{S})-oxiran-2-yl]methyl]-1,3,5-triazinane-2,4,6-trione, 3C-like proteinase, Triglycidyl isocyanurate | | 著者 | Ewert, W, Guenther, S, Reinke, P, Oberthuer, D, Yefanov, O, Gelisio, L, Ginn, H, Lieske, J, Domaracky, M, Brehm, W, Rahmani Mashour, A, White, T.A, Knoska, J, Pena Esperanza, G, Koua, F, Tolstikova, A, Groessler, M, Fischer, P, Hennicke, V, Fleckenstein, H, Trost, F, Galchenkova, M, Gevorkov, Y, Li, C, Awel, S, Paulraj, L.X, Ullah, N, Falke, S, Alves Franca, B, Schwinzer, M, Brognaro, H, Werner, N, Perbandt, M, Tidow, H, Seychell, B, Beck, T, Meier, S, Doyle, J.J, Giseler, H, Melo, D, Dunkel, I, Lane, T.J, Peck, A, Saouane, S, Hakanpaeae, J, Meyer, J, Noei, H, Gribbon, P, Ellinger, B, Kuzikov, M, Wolf, M, Zhang, L, Ehrt, C, Pletzer-Zelgert, J, Wollenhaupt, J, Feiler, C, Weiss, M, Schulz, E.C, Mehrabi, P, Norton-Baker, B, Schmidt, C, Lorenzen, K, Schubert, R, Han, H, Chari, A, Fernandez Garcia, Y, Turk, D, Hilgenfeld, R, Rarey, M, Zaliani, A, Chapman, H.N, Pearson, A, Betzel, C, Meents, A. | | 登録日 | 2020-10-22 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease.
Science, 372, 2021
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7AWU
 | | Structure of SARS-CoV-2 Main Protease bound to LSN2463359. | | 分子名称: | 3C-like proteinase, CHLORIDE ION, ~{N}-propan-2-yl-5-(2-pyridin-4-ylethynyl)pyridine-2-carboxamide | | 著者 | Ewert, W, Guenther, S, Reinke, P, Oberthuer, D, Yefanov, O, Gelisio, L, Ginn, H, Lieske, J, Domaracky, M, Brehm, W, Rahmani Mashour, A, White, T.A, Knoska, J, Pena Esperanza, G, Koua, F, Tolstikova, A, Groessler, M, Fischer, P, Hennicke, V, Fleckenstein, H, Trost, F, Galchenkova, M, Gevorkov, Y, Li, C, Awel, S, Paulraj, L.X, Ullah, N, Falke, S, Alves Franca, B, Schwinzer, M, Brognaro, H, Werner, N, Perbandt, M, Tidow, H, Seychell, B, Beck, T, Meier, S, Doyle, J.J, Giseler, H, Melo, D, Dunkel, I, Lane, T.J, Peck, A, Saouane, S, Hakanpaeae, J, Meyer, J, Noei, H, Gribbon, P, Ellinger, B, Kuzikov, M, Wolf, M, Zhang, L, Ehrt, C, Pletzer-Zelgert, J, Wollenhaupt, J, Feiler, C, Weiss, M, Schulz, E.C, Mehrabi, P, Norton-Baker, B, Schmidt, C, Lorenzen, K, Schubert, R, Han, H, Chari, A, Fernandez Garcia, Y, Turk, D, Hilgenfeld, R, Rarey, M, Zaliani, A, Chapman, H.N, Pearson, A, Betzel, C, Meents, A. | | 登録日 | 2020-11-09 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease.
Science, 372, 2021
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6S4O
 | | The crystal structure of glycogen phosphorylase in complex with 9 | | 分子名称: | (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(2-naphthalen-2-yl-1~{H}-imidazol-4-yl)oxane-3,4,5-triol, Glycogen phosphorylase, muscle form, ... | | 著者 | Kyriakis, E, Solovou, T.G.A, Papaioannou, O.S.E, Skamnaki, V.T, Leonidas, D.D. | | 登録日 | 2019-06-28 | | 公開日 | 2020-02-19 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | The architecture of hydrogen and sulfur sigma-hole interactions explain differences in the inhibitory potency of C-beta-d-glucopyranosyl thiazoles, imidazoles and an N-beta-d glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insights to structure-based design.
Bioorg.Med.Chem., 28, 2020
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