6OYU

Structure of an ancestral-reconstructed cytochrome P450 1B1 with alpha-naphthoflavone

Summary for 6OYU

Entry DOI	10.2210/pdb6oyu/pdb
Descriptor	Cytochrome P450 1B1, 2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total)
Functional Keywords	cyp1b1, ancestral reconstruction, mammalian, oxidoreductase
Biological source	synthetic construct
Total number of polymer chains	2
Total formula weight	114663.87
Authors	Bart, A.G.,Harris, K.L.,Scott, E.E. (deposition date: 2019-05-15, release date: 2020-03-18, Last modification date: 2023-10-11)
Primary citation	Bart, A.G.,Harris, K.L.,Gillam, E.M.J.,Scott, E.E. Structure of an ancestral mammalian family 1B1 cytochrome P450 with increased thermostability. J.Biol.Chem., 295:5640-5653, 2020 Cited by PubMed: 32156703 DOI: 10.1074/jbc.RA119.010727 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.95 Å)

Structure validation