Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0020037 | molecular_function | heme binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| B | 0020037 | molecular_function | heme binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue BHF A 601 |
| Chain | Residue |
| A | VAL126 |
| A | ALA330 |
| A | ASP333 |
| A | ALA133 |
| A | PHE134 |
| A | HIS227 |
| A | ASN228 |
| A | PHE231 |
| A | THR325 |
| A | ASP326 |
| A | GLY329 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue BHF A 602 |
| Chain | Residue |
| A | SER239 |
| A | ILE399 |
| A | PRO400 |
| A | PHE421 |
| A | BHF603 |
| A | GOL606 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue BHF A 603 |
| Chain | Residue |
| A | SER122 |
| A | PHE123 |
| A | PHE134 |
| A | PHE231 |
| A | SER239 |
| A | LEU509 |
| A | BHF602 |
| A | GOL606 |
| A | HOH701 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue BHF A 604 |
| Chain | Residue |
| A | PRO58 |
| A | PRO70 |
| A | LEU89 |
| A | SER239 |
| A | LEU240 |
| A | TYR507 |
| A | GLY508 |
| B | TRP246 |
| site_id | AC5 |
| Number of Residues | 20 |
| Details | binding site for residue HEM A 605 |
| Chain | Residue |
| A | ARG117 |
| A | LEU132 |
| A | ALA133 |
| A | TRP141 |
| A | ARG145 |
| A | ILE327 |
| A | SER331 |
| A | THR334 |
| A | LEU335 |
| A | VAL395 |
| A | THR398 |
| A | ILE399 |
| A | HIS401 |
| A | ILE462 |
| A | PHE463 |
| A | SER464 |
| A | ARG468 |
| A | CYS470 |
| A | ILE471 |
| A | LEU475 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 606 |
| Chain | Residue |
| A | PRO70 |
| A | HIS71 |
| A | PRO396 |
| A | TYR507 |
| A | GLY508 |
| A | BHF602 |
| A | BHF603 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 607 |
| Chain | Residue |
| A | PHE391 |
| A | SER392 |
| A | TRP425 |
| A | HIS429 |
| A | GLU438 |
| A | PHE505 |
| A | ILE511 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | binding site for residue BHF B 601 |
| Chain | Residue |
| B | VAL126 |
| B | PHE134 |
| B | HIS227 |
| B | ASN228 |
| B | PHE231 |
| B | PHE268 |
| B | THR325 |
| B | ASP326 |
| B | GLY329 |
| B | ALA330 |
| B | ASP333 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | binding site for residue BHF B 602 |
| Chain | Residue |
| B | PHE120 |
| B | SER239 |
| B | ASP242 |
| B | VAL397 |
| B | THR398 |
| B | ILE399 |
| B | PRO400 |
| B | BHF603 |
| B | BHF604 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue BHF B 603 |
| Chain | Residue |
| B | SER122 |
| B | PHE134 |
| B | SER239 |
| B | BHF602 |
| B | HOH708 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue BHF B 604 |
| Chain | Residue |
| A | TRP246 |
| A | PHE250 |
| B | PRO58 |
| B | VAL243 |
| B | GLY508 |
| B | BHF602 |
| site_id | AD3 |
| Number of Residues | 19 |
| Details | binding site for residue HEM B 605 |
| Chain | Residue |
| B | ARG117 |
| B | ALA133 |
| B | TRP141 |
| B | ARG145 |
| B | ILE327 |
| B | SER331 |
| B | THR334 |
| B | LEU335 |
| B | VAL395 |
| B | ILE399 |
| B | HIS401 |
| B | ILE462 |
| B | PHE463 |
| B | SER464 |
| B | ARG468 |
| B | ARG469 |
| B | CYS470 |
| B | ILE471 |
| B | SER476 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 606 |
| Chain | Residue |
| B | PRO70 |
| B | HIS71 |
| B | TYR507 |
| B | GLY508 |
| B | LEU509 |
| B | ILE511 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 607 |
| Chain | Residue |
| A | ARG164 |
| B | GLN159 |
| B | ARG161 |
| B | ARG164 |
| B | ALA288 |
| B | PRO289 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 608 |
| Chain | Residue |
| B | PHE123 |
| B | GLN124 |
| B | VAL126 |
| B | GLY129 |
| B | SER131 |
| B | PHE134 |
| B | GLY135 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 609 |
| Chain | Residue |
| B | GLU220 |
| B | GLY223 |
| B | LEU224 |
| B | ASP267 |
| B | PHE271 |
Functional Information from PROSITE/UniProt
| site_id | PS00086 |
| Number of Residues | 10 |
| Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FSvGKRRCIG |
| Chain | Residue | Details |
| A | PHE463-GLY472 | |
