7XEJ
 
 | | SufS with D-cysteine for 5 min | | 分子名称: | (2~{S})-2-[(~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3-sulfanyl-propanoic acid, 1,2-ETHANEDIOL, Cysteine desulfurase SufS, ... | | 著者 | Nakamiura, R, Fujishiro, T. | | 登録日 | 2022-03-31 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | X-ray crystallographic snapshots of the thioazolidine formation upon the PLP during inhibition of SufS by D-cysteine
to be published
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7XED
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7XEB
 | | Collagenase from Grimontia (Vibrio) hollisae 1706B complexed with Gly-Pro-Hyp | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, GLY-PRO-HYP peptide, ... | | 著者 | Ikeuchi, T, Yasumoto, M, Takita, T, Mizutani, K, Mikami, B, Tanaka, K, Hattori, S, Yasukawa, K. | | 登録日 | 2022-03-30 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Crystal structure of Grimontia hollisae collagenase provides insights into its novel substrate specificity toward collagen.
J.Biol.Chem., 298, 2022
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7XEA
 | | T4 lysozyme mutant-S44C/C54T/N68C/A93C/C97A/T115C, DMSO 40%, and then backsoaking | | 分子名称: | CHLORIDE ION, Endolysin, GLYCEROL, ... | | 著者 | Tamada, T, Hiromoto, T. | | 登録日 | 2022-03-30 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Creation of Cross-Linked Crystals With Intermolecular Disulfide Bonds Connecting Symmetry-Related Molecules Allows Retention of Tertiary Structure in Different Solvent Conditions.
Front Mol Biosci, 9, 2022
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7XE9
 | | T4 lysozyme mutant-S44C/C54T/N68C/A93C/C97A/T115C, DMSO 20% | | 分子名称: | CHLORIDE ION, DIMETHYL SULFOXIDE, Endolysin, ... | | 著者 | Tamada, T, Hiromoto, T. | | 登録日 | 2022-03-30 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Creation of Cross-Linked Crystals With Intermolecular Disulfide Bonds Connecting Symmetry-Related Molecules Allows Retention of Tertiary Structure in Different Solvent Conditions.
Front Mol Biosci, 9, 2022
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7XE7
 | | T4 lysozyme mutant-S44C/C54T/N68C/A93C/C97A/T115C, pH10 | | 分子名称: | Endolysin, GLYCEROL, HEXANE-1,6-DIOL | | 著者 | Tamada, T, Hiromoto, T. | | 登録日 | 2022-03-30 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Creation of Cross-Linked Crystals With Intermolecular Disulfide Bonds Connecting Symmetry-Related Molecules Allows Retention of Tertiary Structure in Different Solvent Conditions.
Front Mol Biosci, 9, 2022
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7XE6
 | | T4 lysozyme mutant-S44C/C54T/N68C/A93C/C97A/T115C, pH7 | | 分子名称: | Endolysin, GLYCEROL, HEXANE-1,6-DIOL, ... | | 著者 | Tamada, T, Hiromoto, T. | | 登録日 | 2022-03-30 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Creation of Cross-Linked Crystals With Intermolecular Disulfide Bonds Connecting Symmetry-Related Molecules Allows Retention of Tertiary Structure in Different Solvent Conditions.
Front Mol Biosci, 9, 2022
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7XE5
 | | T4 lysozyme mutant-S44C/C54T/N68C/A93C/C97A/T115C, pH4 | | 分子名称: | Endolysin, GLYCEROL, HEXANE-1,6-DIOL, ... | | 著者 | Tamada, T, Hiromoto, T. | | 登録日 | 2022-03-30 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Creation of Cross-Linked Crystals With Intermolecular Disulfide Bonds Connecting Symmetry-Related Molecules Allows Retention of Tertiary Structure in Different Solvent Conditions.
Front Mol Biosci, 9, 2022
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7XE4
 | | structure of a membrane-bound glycosyltransferase | | 分子名称: | (11R,14S)-17-amino-14-hydroxy-8,14-dioxo-9,13,15-trioxa-14lambda~5~-phosphaheptadecan-11-yl decanoate, 1,3-beta-glucan synthase component FKS1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Hu, X.L, Yang, P, Zhang, M, Liu, X.T, Yu, H.J. | | 登録日 | 2022-03-29 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-04-19 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural and mechanistic insights into fungal beta-1,3-glucan synthase FKS1.
Nature, 616, 2023
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7XE3
 | | Crystal structure of LSD2 in complex with cis-4-Br-2,5-F2-PCPA (S1024) | | 分子名称: | 1,2-ETHANEDIOL, 3-[4-bromanyl-2,5-bis(fluoranyl)phenyl]propanal, CITRATE ANION, ... | | 著者 | Niwa, H, Sato, S, Umehara, T. | | 登録日 | 2022-03-29 | | 公開日 | 2022-09-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | | 主引用文献 | Structure-Activity Relationship and In Silico Evaluation of cis- and trans-PCPA-Derived Inhibitors of LSD1 and LSD2
Acs Med.Chem.Lett., 13, 2022
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7XE2
 | | Crystal structure of LSD2 in complex with trans-4-Br-PCPA | | 分子名称: | 3-(4-bromophenyl)propanal, CITRATE ANION, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Niwa, H, Sato, S, Umehara, T. | | 登録日 | 2022-03-29 | | 公開日 | 2022-09-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure-Activity Relationship and In Silico Evaluation of cis- and trans-PCPA-Derived Inhibitors of LSD1 and LSD2
Acs Med.Chem.Lett., 13, 2022
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7XE1
 | | Crystal structure of LSD2 in complex with cis-4-Br-PCPA | | 分子名称: | 3-(4-bromophenyl)propanal, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Niwa, H, Sato, S, Umehara, T. | | 登録日 | 2022-03-29 | | 公開日 | 2022-09-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Structure-Activity Relationship and In Silico Evaluation of cis- and trans-PCPA-Derived Inhibitors of LSD1 and LSD2
Acs Med.Chem.Lett., 13, 2022
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7XDU
 | | TtherAmDH-NAD+ | | 分子名称: | 4-hydroxy-tetrahydrodipicolinate reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Chen, C, Qian, Y.Y, Pan, J, Bai, Y.P, Xu, J.H. | | 登録日 | 2022-03-28 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Stereoselective synthesis of chiral lactams via an engineered natural amine dehydrogenase.
To Be Published
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7XD9
 | | Crystal Structure of Dengue Virus serotype 2 (DENV2) Polymerase Elongation Complex (CTP Form) | | 分子名称: | CYTIDINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Wu, J, Wang, X, Gong, P. | | 登録日 | 2022-03-26 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Structural basis of transition from initiation to elongation in de novo viral RNA-dependent RNA polymerases.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7XD8
 | | Crystal Structure of Dengue Virus Serotype 2 (DENV2) Polymerase Elongation Complex (Native Form) | | 分子名称: | GLYCEROL, NS5, RNA (30-mer), ... | | 著者 | Wu, J, Wang, X, Gong, P. | | 登録日 | 2022-03-26 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structural basis of transition from initiation to elongation in de novo viral RNA-dependent RNA polymerases.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7XCN
 | | Crystal structure of the MttB-MttC complex at 2.7 A resolution | | 分子名称: | 5-HYDROXYBENZIMIDAZOLYLCOBAMIDE, GLYCEROL, Trimethylamine methyltransferase, ... | | 著者 | Li, J, Chan, M.K. | | 登録日 | 2022-03-24 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Insights into pyrrolysine function from structures of a trimethylamine methyltransferase and its corrinoid protein complex.
Commun Biol, 6, 2023
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7XCM
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7XCL
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7XCE
 | | Crystal structure of Ankyrin G in complex with neurofascin | | 分子名称: | GLYCEROL, Neurofascin,Ankyrin-3, SULFATE ION | | 著者 | He, L, Li, J, Wang, C. | | 登録日 | 2022-03-24 | | 公開日 | 2022-09-21 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of Ankyrin-G in complex with a fragment of Neurofascin reveals binding mechanisms required for integrity of the axon initial segment.
J.Biol.Chem., 298, 2022
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7XCA
 | | Crystal structure of the porcine astrovirus capsid spike domain | | 分子名称: | CHLORIDE ION, Capsid protein spike domain, MAGNESIUM ION | | 著者 | Pan, L.X, Zhang, W.C, Yang, D.F, Yang, L.Y, Liu, H. | | 登録日 | 2022-03-23 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure analysis of porcine astrovirus capsid spike and spike/neutralizing antibody complexes.
To Be Published
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7XC8
 | | Crystal structure of cotton alpha-like expansin GhEXLA1 | | 分子名称: | Beta-expansin, DI(HYDROXYETHYL)ETHER, GLYCEROL | | 著者 | Zhao, F, Men, S, Xue, Y, Tu, L.L, Yin, P, Zhang, X.L. | | 登録日 | 2022-03-23 | | 公開日 | 2023-05-17 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Crystal structure of cotton alpha-like expansin GhEXLA1
To Be Published
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7XC4
 | | Crystal structure of SARS-CoV-2 NSP3 Macrodomain 3 (SARS-unique domain-M) in complex with Oxaprozin | | 分子名称: | 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid, Papain-like protease nsp3 | | 著者 | Li, J, Liu, Y, Gao, J, Ruan, K. | | 登録日 | 2022-03-22 | | 公開日 | 2022-11-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Two Binding Sites of SARS-CoV-2 Macrodomain 3 Probed by Oxaprozin and Meclomen.
J.Med.Chem., 65, 2022
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7XC1
 | | Crystal structure of ERK2 with an allosteric inhibitor 3 | | 分子名称: | (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... | | 著者 | Yoshida, M, Kinoshita, T. | | 登録日 | 2022-03-22 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structural basis for ERK2 allosteric inhibitors.
To Be Published
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7XBZ
 | | Crystal structure of Staphylococcus aureus ClpP in complex with R-ZG197 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, (6S,9aS)-6-[(2S)-butan-2-yl]-8-[(1R)-1-naphthalen-1-ylethyl]-4,7-bis(oxidanylidene)-N-[4,4,4-tris(fluoranyl)butyl]-3,6,9,9a-tetrahydro-2H-pyrazino[1,2-a]pyrimidine-1-carboxamide, ATP-dependent Clp protease proteolytic subunit, ... | | 著者 | Wei, B.Y, Gan, J.H, Yang, C.-G. | | 登録日 | 2022-03-22 | | 公開日 | 2022-11-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP.
Nat Commun, 13, 2022
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7XBY
 | | The crystal structure of SARS-CoV-2 Omicron BA.1 variant RBD in complex with equine ACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, BROMIDE ION, ... | | 著者 | Xu, Z.P, Liu, K.F, Han, P, Qi, J.X. | | 登録日 | 2022-03-22 | | 公開日 | 2022-06-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Binding and structural basis of equine ACE2 to RBDs from SARS-CoV, SARS-CoV-2 and related coronaviruses.
Nat Commun, 13, 2022
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