5YY9
 
 | | Crystal structure of Tandem Tudor Domain of human UHRF1 in complex with LIG1-K126me3 | | 分子名称: | E3 ubiquitin-protein ligase UHRF1, Ligase 1 | | 著者 | Kori, S, Defossez, P.A, Arita, K. | | 登録日 | 2017-12-08 | | 公開日 | 2018-12-12 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.653 Å) | | 主引用文献 | Structure of the UHRF1 Tandem Tudor Domain Bound to a Methylated Non-histone Protein, LIG1, Reveals Rules for Binding and Regulation.
Structure, 27, 2019
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8RCF
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2PI2
 | | Full-length Replication protein A subunits RPA14 and RPA32 | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, Replication protein A 14 kDa subunit, Replication protein A 32 kDa subunit | | 著者 | Deng, X, Borgstahl, G.E. | | 登録日 | 2007-04-12 | | 公開日 | 2007-10-16 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of the Full-length Human RPA14/32 Complex Gives Insights into the Mechanism of DNA Binding and Complex Formation.
J.Mol.Biol., 374, 2007
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8RCD
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5YYA
 | | Crystal structure of Tandem Tudor Domain of human UHRF1 | | 分子名称: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase UHRF1, SULFATE ION | | 著者 | Kori, S, Defossez, P.A, Arita, K. | | 登録日 | 2017-12-08 | | 公開日 | 2018-12-12 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of the UHRF1 Tandem Tudor Domain Bound to a Methylated Non-histone Protein, LIG1, Reveals Rules for Binding and Regulation.
Structure, 27, 2019
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8S24
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6B40
 | | BbRAGL-3'TIR synaptic complex with nicked DNA refined with C2 symmetry | | 分子名称: | 31TIR intact strand, 31TIR pre-nicked strand of flanking DNA, 31TIR pre-nicked strand of signal DNA, ... | | 著者 | Zhang, Y, Cheng, T.C, Xiong, Y, Schatz, D.G. | | 登録日 | 2017-09-25 | | 公開日 | 2019-03-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Transposon molecular domestication and the evolution of the RAG recombinase.
Nature, 569, 2019
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6FLF
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6FM1
 | | Deoxyguanylosuccinate synthase (DgsS) quaternary structure with ATPanddGMP at 2.3 Angstrom resolution | | 分子名称: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Adenylosuccinate synthetase, ... | | 著者 | Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A. | | 登録日 | 2018-01-29 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes.
Science, 372, 2021
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6FM0
 | | Deoxyguanylosuccinate synthase (DgsS) and ATP structure at 1.7 Angstrom resolution | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Adenylosuccinate synthetase | | 著者 | Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A. | | 登録日 | 2018-01-29 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes.
Science, 372, 2021
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1ZDN
 | | Ubiquitin-conjugating enzyme E2S | | 分子名称: | SODIUM ION, Ubiquitin-conjugating enzyme E2S | | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2005-04-14 | | 公開日 | 2005-05-03 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
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6TNH
 | | Deoxyguanylosuccinate synthase (DgsS) quaternary structure with AMPPcP, dGMP, Asp, Magnesium at 2.21 Angstrom resolution | | 分子名称: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ASPARTIC ACID, Adenylosuccinate synthetase, ... | | 著者 | Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A. | | 登録日 | 2019-12-08 | | 公開日 | 2020-12-16 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes.
Science, 372, 2021
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6H09
 | | HIV capsid hexamer with IP6 ligand | | 分子名称: | Gag polyprotein, INOSITOL HEXAKISPHOSPHATE | | 著者 | James, L.C. | | 登録日 | 2018-07-06 | | 公開日 | 2018-08-15 | | 最終更新日 | 2020-10-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | IP6 is an HIV pocket factor that prevents capsid collapse and promotes DNA synthesis.
Elife, 7, 2018
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5YZ1
 | | Crystal structure of human Archease | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Protein archease | | 著者 | Duan, S.Y, Li, J.X. | | 登録日 | 2017-12-11 | | 公開日 | 2019-01-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Crystal structure of human archease, a key cofactor of tRNA splicing ligase complex.
Int.J.Biochem.Cell Biol., 122, 2020
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2M6N
 | | 3D solution structure of EMI1 (Early Mitotic Inhibitor 1) | | 分子名称: | F-box only protein 5, ZINC ION | | 著者 | Frye, J.J, Brown, N.G, Petzold, G, Watson, E.R, Royappa, G.R, Nourse, A, Jarvis, M, Kriwacki, R.W, Peters, J, Stark, H, Schulman, B.A. | | 登録日 | 2013-04-06 | | 公開日 | 2013-05-29 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Electron microscopy structure of human APC/C(CDH1)-EMI1 reveals multimodal mechanism of E3 ligase shutdown.
Nat.Struct.Mol.Biol., 20, 2013
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2N9E
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3MUD
 | | Structure of the Tropomyosin Overlap Complex from Chicken Smooth Muscle | | 分子名称: | 1,2-ETHANEDIOL, DNA repair protein XRCC4,Tropomyosin alpha-1 chain, SULFATE ION, ... | | 著者 | Klenchin, V.A, Frye, J, Rayment, I. | | 登録日 | 2010-05-02 | | 公開日 | 2010-06-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of the tropomyosin overlap complex from chicken smooth muscle: insight into the diversity of N-terminal recognition .
Biochemistry, 49, 2010
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2KNB
 | | Solution NMR structure of the parkin Ubl domain in complex with the endophilin-A1 SH3 domain | | 分子名称: | E3 ubiquitin-protein ligase parkin, Endophilin-A1 | | 著者 | Trempe, J, Guennadi, K, Edna, C.M, Kalle, G. | | 登録日 | 2009-08-20 | | 公開日 | 2009-12-22 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination.
Mol.Cell, 36, 2009
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6VZE
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6VZ0
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5JK7
 | | The X-ray structure of the DDB1-DCAF1-Vpr-UNG2 complex | | 分子名称: | DNA damage-binding protein 1, Protein VPRBP, Protein Vpr, ... | | 著者 | Calero, G, Ahn, J, Wu, Y. | | 登録日 | 2016-04-26 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.49 Å) | | 主引用文献 | The DDB1-DCAF1-Vpr-UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destruction.
Nat.Struct.Mol.Biol., 23, 2016
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5IYD
 | | Human core-PIC in the initial transcribing state (no IIS) | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | | 著者 | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | | 登録日 | 2016-03-24 | | 公開日 | 2016-05-18 | | 最終更新日 | 2019-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
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5IYC
 | | Human core-PIC in the initial transcribing state | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | | 著者 | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | | 登録日 | 2016-03-24 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
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5IYB
 | | Human core-PIC in the open state | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | | 著者 | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | | 登録日 | 2016-03-24 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
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5BPC
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