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6PUI
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BU of 6pui by Molmil
Structure of human MAIT A-F7 TCR in complex with human MR1-4'OH-Butyl-5-OP-U
分子名称: 6-[(4-hydroxybutyl)amino]-5-[(E)-(2-oxopropylidene)amino]pyrimidine-2,4(1H,3H)-dione, Beta-2-microglobulin, GLYCEROL, ...
著者Awad, W, Keller, A.N, Rossjohn, J.
登録日2019-07-18
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献The molecular basis underpinning the potency and specificity of MAIT cell antigens.
Nat.Immunol., 21, 2020
3KPL
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BU of 3kpl by Molmil
Crystal Structure of HLA B*4402 in complex with EEYLQAFTY a self peptide from the ABCD3 protein
分子名称: Beta-2-microglobulin, EEYLQAFTY, self peptide from the ATP binding cassette protein ABCD3, ...
著者Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J.
登録日2009-11-16
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
7L1C
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BU of 7l1c by Molmil
Crystal structure of HLA-A*03:01 in complex with a mutant PIK3CA peptide
分子名称: Beta-2-microglobulin, FORMIC ACID, GLYCEROL, ...
著者Ma, J, Baker, B.M.
登録日2020-12-14
公開日2022-03-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.
Nat Med, 28, 2022
6BLR
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BU of 6blr by Molmil
Crystal Structure of IAg7 in complex with insulin mimotope p8E9E6SS
分子名称: 1,2-ETHANEDIOL, H2-Ab1 protein, IAg7 alpha chain
著者Wang, Y, Dai, S.
登録日2017-11-11
公開日2017-12-20
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5T7G
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BU of 5t7g by Molmil
Crystal Structure of Murine MHC-I H-2Dd in complex with Murine Beta2-Microglobulin and a Variant of Peptide (PT9) of HIV gp120 MN Isolate (IGPGRAFYT)
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
著者Jiang, J, Natarajan, K, Margulies, D.
登録日2016-09-04
公開日2017-10-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.961 Å)
主引用文献Effects of Cross-Presentation, Antigen Processing, and Peptide Binding in HIV Evasion of T Cell Immunity.
J. Immunol., 200, 2018
5D7J
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BU of 5d7j by Molmil
Structure of human MR1-5-OP-RU in complex with human MAIT M33.64(Y95alphaF) TCR
分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ...
著者Keller, A.N, Woolley, R.E, Rossjohn, J.
登録日2015-08-14
公開日2016-01-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition.
Immunity, 44, 2016
4EOW
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BU of 4eow by Molmil
Crystal structure of a disease-associated anti-human GM-CSF autoantibody MB007
分子名称: MB007 IgG1 Fab fragment light chain, MB007 human IgG1 Fab fragment heavy chain
著者Blech, M.
登録日2012-04-16
公開日2012-08-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Molecular structure of human GM-CSF in complex with a disease-associated anti-human GM-CSF autoantibody and its potential biological implications.
Biochem.J., 447, 2012
7EMB
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BU of 7emb by Molmil
Mooring Stone-Like Arg114 Pulls Diverse Bulged Peptides: First Insight into African Swine Fever Virus-Derived T Cell Epitopes Presented by Swine Major Histocompatibility Complex Class I
分子名称: ALA-ALA-ALA-ILE-GLU-GLU-GLU-ASP-ILE, Beta-2-microglobulin, Leucocyte antigen
著者Yue, C, Xiang, W, Huang, X, Sun, Y, Xiao, J, Liu, K, Sun, Z, Qiao, P, Li, H, Gan, J, Ba, L, Chai, Y, Qi, J, Liu, P, Qi, P, Zhao, Y, Li, Y, Qiu, H.J, Gao, G.F, Gao, G, Liu, W.J.
登録日2021-04-13
公開日2021-12-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Mooring Stone-Like Arg 114 Pulls Diverse Bulged Peptides: First Insight into African Swine Fever Virus-Derived T Cell Epitopes Presented by Swine Major Histocompatibility Complex Class I.
J.Virol., 96, 2022
7APZ
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BU of 7apz by Molmil
CLIP peptide bound to chicken MHC class II molecule (BL-2) from B2 haplotype with a decamer mode of binding
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYL GROUP, DI(HYDROXYETHYL)ETHER, ...
著者Halabi, S, Kaufman, J.
登録日2020-10-20
公開日2021-11-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献CLIP peptide bound to chicken MHC class II molecule (BL-2) from B2 haplotype with a decamer mode of binding
To Be Published
5EU3
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BU of 5eu3 by Molmil
HLA Class I antigen
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K.
登録日2015-11-18
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
5M3V
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BU of 5m3v by Molmil
BEAT Fc
分子名称: Ig gamma-1 chain C region, Ig gamma-1 chain C region,Ig gamma-3 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Skegro, D, Stutz, C, Bourquin, F, Blein, S.
登録日2016-10-17
公開日2017-05-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Immunoglobulin domain interface exchange as a platform technology for the generation of Fc heterodimers and bispecific antibodies.
J. Biol. Chem., 292, 2017
7LGT
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BU of 7lgt by Molmil
HLA-B*07:02 in complex with 229E-derived coronavirus nucleocapsid peptide N75-83
分子名称: BROMIDE ION, Beta-2-microglobulin, CHLORIDE ION, ...
著者Gras, S, Szeto, C, Chatzileontiadou, D.S.M.
登録日2021-01-21
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献CD8 + T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses.
Immunity, 54, 2021
5C0C
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BU of 5c0c by Molmil
1E6 TCR in complex with HLA-A02 carrying RQFGPDWIVA
分子名称: 1,2-ETHANEDIOL, 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, ...
著者Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K.
登録日2015-06-12
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.974 Å)
主引用文献Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
3QCU
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BU of 3qcu by Molmil
Crystal structure of the LT3015 antibody Fab fragment in complex with lysophosphatidic acid (14:0)
分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, LT3015 antibody Fab fragment, heavy chain, ...
著者Fleming, J.K, Wojciak, J.M, Campbell, M.-A, Huxford, T.
登録日2011-01-17
公開日2011-03-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.979 Å)
主引用文献Biochemical and structural characterization of lysophosphatidic Acid binding by a humanized monoclonal antibody.
J.Mol.Biol., 408, 2011
5E8O
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BU of 5e8o by Molmil
The structure of the TEIPP associated altered peptide ligand Trh4-p2ABU in complex with H-2D(b)
分子名称: Beta-2-microglobulin, Ceramide synthase 5, H-2 class I histocompatibility antigen, ...
著者Hafstrand, I, Doorduijn, E, Duru, A.D, Buratto, J, Oliveira, C.C, Sandalova, T, van Hall, T, Achour, A.
登録日2015-10-14
公開日2016-02-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献The MHC Class I Cancer-Associated Neoepitope Trh4 Linked with Impaired Peptide Processing Induces a Unique Noncanonical TCR Conformer.
J Immunol., 196, 2016
6V3J
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BU of 6v3j by Molmil
KIR3DL1 in complex with HLA-B*57:03 presenting the peptide LSSPVTKSF
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, HLA-B alpha chain (B*5703GB), ...
著者Maclachlan, B, Rossjohn, J, Vivian, J.P.
登録日2019-11-25
公開日2020-05-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ATI
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BU of 6ati by Molmil
HLA-DRB1*1402 in complex with Vimentin-64Cit59-71
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ...
著者Scally, S.W, Ting, Y.T, Rossjohn, J.
登録日2017-08-29
公開日2017-09-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis.
Ann. Rheum. Dis., 76, 2017
3WS6
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BU of 3ws6 by Molmil
Crystal Structure of H-2D in complex with a mimotopic peptide
分子名称: Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ...
著者Kumar, P.R, Mukherjee, G, Samanta, D, DiLorenzo, T.P, Almo, S.C, Immune Function Network, New York Structural Genomics Research Consortium (NYSGRC)
登録日2014-02-28
公開日2014-03-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Compensatory mechanisms allow undersized anchor-deficient class I MHC ligands to mediate pathogenic autoreactive T cell responses
J. Immunol., 193, 2014
4O2E
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BU of 4o2e by Molmil
A peptide complexed with HLA-B*3901
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-39 alpha chain, ...
著者Sun, M, Liu, J, Qi, J, Tefsen, B, Shi, Y, Yan, J, Gao, G.F.
登録日2013-12-17
公開日2014-07-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.981 Å)
主引用文献N alpha-terminal acetylation for T cell recognition: molecular basis of MHC class I-restricted n alpha-acetylpeptide presentation
J.Immunol., 192, 2014
6C5H
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BU of 6c5h by Molmil
S25-5 Fab in complex with Chlamydiaceae-specific LPS antigen
分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-8)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-amino-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Evans, S.V, Haji-Ghassemi, O.
登録日2018-01-16
公開日2019-01-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody-Carbohydrate Binding Affinity by an Order of Magnitude.
Biochemistry, 58, 2019
5JLZ
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BU of 5jlz by Molmil
Crystal structure of HLA-DRB1*04:01 in complex with modified alpha-enolase peptide 26-40 with citrulline at the position 32
分子名称: Alpha-enolase, HLA class II histocompatibility antigen, DR alpha chain, ...
著者Dubnovitsky, A, Kozhukh, G, Sandalova, T, Achour, A.
登録日2016-04-28
公開日2016-12-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted alpha-Enolase T Cell Epitope in Rheumatoid Arthritis.
Front Immunol, 7, 2016
1S7S
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BU of 1s7s by Molmil
Crystal structures of the murine class I major histocompatibility complex H-2Kb in complex with LCMV-derived gp33 index peptide and three of its escape variants
分子名称: Beta-2-microglobulin, Glycoprotein 9-residue peptide, H-2 class I histocompatibility antigen, ...
著者Velloso, L.M, Michaelsson, J, Ljunggren, H.G, Schneider, G, Achour, A.
登録日2004-01-30
公開日2004-05-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition.
J.Immunol., 172, 2004
1S7Q
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BU of 1s7q by Molmil
Crystal structures of the murine class I major histocompatibility complex H-2Kb in complex with LCMV-derived gp33 index peptide and three of its escape variants
分子名称: Beta-2-microglobulin, Glycoprotein 9-residue peptide, H-2 class I histocompatibility antigen, ...
著者Velloso, L.M, Michaelsson, J, Ljunggren, H.G, Schneider, G, Achour, A.
登録日2004-01-30
公開日2004-05-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition.
J.Immunol., 172, 2004
7SU9
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BU of 7su9 by Molmil
KRAS-G12D specific TCR9a in complex with C*05-GADGVGKSL
分子名称: Beta-2-microglobulin, GLYCEROL, KRAS-G12D-9mer with A18L substitution, ...
著者Sim, M.J.W, Sun, P.D.
登録日2021-11-16
公開日2022-06-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献T cells discriminate between groups C1 and C2 HLA-C.
Elife, 11, 2022
6E1I
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BU of 6e1i by Molmil
HLA-A*0201 single chain trimer with murine H2K alpha 3 domain and HPV.16 E7 peptide YMLDLQPET
分子名称: HLA-A*0201 single chain trimer with murine H2K alpha 3 domain and HPV.16 E7 peptide YMLDLQPET
著者Finton, K.A.K, Rusnac, D.V.
登録日2018-07-09
公開日2019-07-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Effects of HLA single chain trimer design on peptide presentation and stability
To Be Published

221716

件を2024-06-26に公開中

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