PDB: 22634 件ウェブページステータス検索Chemie searchBIRD

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3MKA	Crystal Structure of Mycobacterium Tuberculosis Proteasome with propetide and an T1A mutation at beta-subunit 分子名称: Proteasome subunit alpha, Proteasome subunit beta 著者 Li, D, Li, H. 登録日 2010-04-14 公開日 2010-05-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Structural basis for the assembly and gate closure mechanisms of the Mycobacterium tuberculosis 20S proteasome. Embo J., 29, 2010
5J5D	Crystal structure of Dihydrodipicolinate Synthase from Mycobacterium tuberculosis in complex with alpha-ketopimelic acid 分子名称: 2-oxoheptanedioic acid, 4-hydroxy-tetrahydrodipicolinate synthase, SODIUM ION 著者 Navratna, V, Gopal, B. 登録日 2016-04-02 公開日 2016-08-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Inhibition of Mycobacterium tuberculosis dihydrodipicolinate synthase by alpha-ketopimelic acid and its other structural analogues Sci Rep, 6, 2016
5U3F	Structure of Mycobacterium tuberculosis IlvE, a branched-chain amino acid transaminase, in complex with D-cycloserine derivative 分子名称: (5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate, Branched-chain-amino-acid aminotransferase 著者 Favrot, L, Amorim Franco, T.M, Blanchard, J.S. 登録日 2016-12-02 公開日 2017-03-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.695 Å) 主引用文献 Mechanism-Based Inhibition of the Mycobacterium tuberculosis Branched-Chain Aminotransferase by d- and l-Cycloserine. ACS Chem. Biol., 12, 2017
5D19	Crystal structure of Mycobacterium tuberculosis Rv0302, form II 分子名称: TetR family transcriptional regulator 著者 Chou, T.-H, Delmar, J, Su, C.-C, Yu, E. 登録日 2015-08-04 公開日 2015-10-07 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.655 Å) 主引用文献 Crystal structure of the Mycobacterium tuberculosis transcriptional regulator Rv0302. Protein Sci., 2015
5JZX	Crystal Structure of UDP-N-acetylenolpyruvoylglucosamine reductase (MurB) from Mycobacterium tuberculosis 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, POTASSIUM ION, UDP-N-acetylenolpyruvoylglucosamine reductase 著者 Dharavath, S, Eniyan, K, Bajpai, U, Gourinath, S. 登録日 2016-05-17 公開日 2017-05-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of UDP-N-acetylglucosamine-enolpyruvate reductase (MurB) from Mycobacterium tuberculosis Biochim. Biophys. Acta, 1866, 2017
5D18	Crystal structure of Mycobacterium tuberculosis Rv0302, form I 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ISOPROPYL ALCOHOL, SODIUM ION, ... 著者 Chou, T.-H, Delmar, J, Su, C.-C, Yu, E. 登録日 2015-08-04 公開日 2015-10-07 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Crystal structure of the Mycobacterium tuberculosis transcriptional regulator Rv0302. Protein Sci., 2015
4Z0M	EchA5 Mycobacterium tuberculosis 分子名称: Enoyl-CoA hydratase 著者 Chaudhary, S, Gokhale, R.S. 登録日 2015-03-26 公開日 2016-02-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Unsaturated Lipid Assimilation by Mycobacteria Requires Auxiliary cis-trans Enoyl CoA Isomerase Chem.Biol., 22, 2015
3MI0	Crystal Structure of Mycobacterium Tuberculosis Proteasome at 2.2 A 分子名称: (2R,3S,4R)-2-[(S)-(1S)-cyclohex-2-en-1-yl(hydroxy)methyl]-4-ethyl-3-hydroxy-3-methyl-5-oxopyrrolidine-2-carbaldehyde, DIMETHYLFORMAMIDE, Proteasome subunit alpha, ... 著者 Li, D, Li, H. 登録日 2010-04-09 公開日 2010-06-23 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis for the assembly and gate closure mechanisms of the Mycobacterium tuberculosis 20S proteasome. Embo J., 2010
3NFW	Crystal structure of nitrilotriacetate monooxygenase component B (A0R521 homolog) from Mycobacterium thermoresistibile 分子名称: Flavin reductase-like, FMN-binding protein, GLYCEROL 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-06-10 公開日 2010-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of nitrilotriacetate monooxygenase component B from Mycobacterium thermoresistibile. Acta Crystallogr.,Sect.F, 67, 2011
6G7D	Structure of MeT1 from Mycobacterium hassiacum in complex with SAM and glycerol. 分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... 著者 Pereira, P.J.B, Ripoll-Rozada, J. 登録日 2018-04-05 公開日 2019-01-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Biosynthesis of mycobacterial methylmannose polysaccharides requires a unique 1-O-methyltransferase specific for 3-O-methylated mannosides. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
5EBV	Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor 11c and CoA 分子名称: 5-(4-chlorophenyl)-~{N}-[3-(3,4-dihydro-1~{H}-isoquinolin-2-yl)propyl]-4-methyl-1,1-bis(oxidanylidene)-1,2-thiazol-3-amine, CHLORIDE ION, COENZYME A, ... 著者 Gajadeera, C.S, Hou, C, Garneau-Tsodikova, S, Tsodikov, O.V. 登録日 2015-10-19 公開日 2016-03-30 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Potent Inhibitors of Acetyltransferase Eis Overcome Kanamycin Resistance in Mycobacterium tuberculosis. Acs Chem.Biol., 11, 2016
5EC4	Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor 13g and CoA 分子名称: 5-(3-chlorophenyl)-4-methyl-~{N}-(3-morpholin-4-ylpropyl)-1,1-bis(oxidanylidene)-1,2-thiazol-3-amine, COENZYME A, Enhanced intracellular survival protein 著者 Gajadeera, C.S, Hou, C, Garneau-Tsodikova, S, Tsodikov, O.V. 登録日 2015-10-20 公開日 2016-03-30 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Potent Inhibitors of Acetyltransferase Eis Overcome Kanamycin Resistance in Mycobacterium tuberculosis. Acs Chem.Biol., 11, 2016
6G80	Structure of Mycobacterium hassiacum MeT1 from orthorhombic crystals. 分子名称: GLYCEROL, Methyltransferase domain protein, S-ADENOSYL-L-HOMOCYSTEINE 著者 Pereira, P.J.B, Ripoll-Rozada, J. 登録日 2018-04-06 公開日 2019-01-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Biosynthesis of mycobacterial methylmannose polysaccharides requires a unique 1-O-methyltransferase specific for 3-O-methylated mannosides. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
3LWB	Crystal Structure of apo D-alanine:D-alanine Ligase (Ddl) from Mycobacterium tuberculosis 分子名称: D-alanine--D-alanine ligase, NITRATE ION 著者 Bruning, J.B, Murillo, A.C, Chacon, O, Barletta, R.G, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2010-02-23 公開日 2010-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of the Mycobacterium tuberculosis D-Alanine:D-Alanine Ligase, a Target of the Antituberculosis Drug D-Cycloserine. Antimicrob.Agents Chemother., 55, 2011
2BMX	Mycobacterium tuberculosis AhpC 分子名称: ALKYL HYDROPEROXIDASE C 著者 Guimaraes, B.G, Alzari, P.M. 登録日 2005-03-16 公開日 2005-05-10 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure and Mechanism of the Alkyl Hydroperoxidase Ahpc, a Key Element of the Mycobacterium Tuberculosis Defense System Against Oxidative Stress. J.Biol.Chem., 280, 2005
2BVC	Crystal structure of Mycobacterium tuberculosis glutamine synthetase in complex with a transition state mimic 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLUTAMINE SYNTHETASE 1, ... 著者 Krajewski, W.W, Jones, T.A, Mowbray, S.L. 登録日 2005-06-23 公開日 2005-07-07 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of Mycobacterium Tuberculosis Glutamine Synthetase in Complex with a Transition-State Mimic Provides Functional Insights. Proc.Natl.Acad.Sci.USA, 102, 2005
6D5A	Crystal structure of L,D-transpeptidase 5 from Mycobacterium tuberculosis in apo form 分子名称: L,D-transpeptidase 5, TETRAETHYLENE GLYCOL 著者 Libreros, G.A, Dias, M.V. 登録日 2018-04-19 公開日 2019-02-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.622 Å) 主引用文献 Structural Basis for the Interaction and Processing of beta-Lactam Antibiotics by l,d-Transpeptidase 3 (LdtMt3) from Mycobacterium tuberculosis. ACS Infect Dis, 5, 2019
6B0U	Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with a Lys-containing peptide 分子名称: COENZYME A, N-acetyltransferase Eis, Synthetic peptide ATKAPAKKA 著者 Biswas, T, Pang, A.H, Garneau-Tsodikova, S, Tsodikov, O.V. 登録日 2017-09-15 公開日 2018-01-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Acetylation by Eis and Deacetylation by Rv1151c of Mycobacterium tuberculosis HupB: Biochemical and Structural Insight. Biochemistry, 57, 2018
6EDZ	Crystal structure of Mycobacterium tuberculosis ICL2 in complex with acetyl-CoA, form I 分子名称: ACETYL COENZYME *A, Isocitrate lyase 2 著者 Bashiri, G, Bhusal, R, Leung, I. 登録日 2018-08-12 公開日 2019-08-14 最終更新日 2019-10-23 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2. Nat Commun, 10, 2019
6I2P	Crystal structure of the Mycobacterium tuberculosis PknB kinase domain (L33E mutant) in complex with its substrate GarA 分子名称: Glycogen accumulation regulator GarA, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... 著者 Andre-Leroux, G, Hindie, V, Barilone, N, Bellinzoni, M, Alzari, P.M. 登録日 2018-11-01 公開日 2019-05-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling. Sci.Signal., 12, 2019
6EDW	Crystal structure of Mycobacterium tuberculosis ICL2 in the apo form 分子名称: GLYCEROL, Isocitrate lyase 2, MAGNESIUM ION 著者 Bashiri, G, Bhusal, R, Leung, I. 登録日 2018-08-12 公開日 2019-08-14 最終更新日 2019-10-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2. Nat Commun, 10, 2019
6EE1	Crystal structure of Mycobacterium tuberculosis ICL2 in complex with acetyl-CoA 分子名称: ACETYL COENZYME *A, Isocitrate lyase 2, MAGNESIUM ION 著者 Bashiri, G, Bhusal, R, Leung, I. 登録日 2018-08-12 公開日 2019-08-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2. Nat Commun, 10, 2019
5CRF	Structure of the penicillin-binding protein PonA1 from Mycobacterium Tuberculosis 分子名称: PHOSPHATE ION, Penicillin-binding protein 1A 著者 Filippova, E.V, Wawrzak, Z, Kiryukhina, O, Kieser, K, Endres, M, Rubin, E, Sacchettini, J, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) 登録日 2015-07-22 公開日 2016-05-04 最終更新日 2016-07-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structures of the transpeptidase domain of the Mycobacterium tuberculosis penicillin-binding protein PonA1 reveal potential mechanisms of antibiotic resistance. Febs J., 283, 2016
5UH7	Crystal structure of beta'MtbSI of Mycobacterium tuberculosis RNA polymerase 分子名称: DNA-directed RNA polymerase subunit beta' 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2017-01-11 公開日 2017-04-12 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.199 Å) 主引用文献 Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
6ITO	Crystal structure of pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate, AMP and inhibitor Ribose 5-Phosphate 分子名称: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, OXALATE ION, ... 著者 Zhong, W, Cai, Q, El Sahili, A, Mu, Y, Lescar, J, Dedon, P.C. 登録日 2018-11-24 公開日 2019-08-14 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Pyruvate Kinase Regulates the Pentose-Phosphate Pathway in Response to Hypoxia in Mycobacterium tuberculosis. J.Mol.Biol., 431, 2019

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