3QES
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![BU of 3qes by Molmil](/molmil-images/mine/3qes) | RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dGTP Opposite Difluorotoluene Nucleoside | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... | 著者 | Xia, S, Konigsberg, W.H, Wang, J. | 登録日 | 2011-01-20 | 公開日 | 2012-01-25 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structural Basis for Differential Insertion Kinetics of dNMPs Opposite a Difluorotoluene Nucleotide Residue. Biochemistry, 51, 2012
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2VA2
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![BU of 2va2 by Molmil](/molmil-images/mine/2va2) | Complex structure of Sulfolobus solfataricus DPO4 and DNA duplex containing a hydrophobic thymine isostere 2,4-difluorotoluene nucleotide in the template strand | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *CP*TP*A)-3', 5'-D(*TP*TP*CP*AP*GP*DFTP*AP*GP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ... | 著者 | Irimia, A, Pallan, P.S, Egli, M. | 登録日 | 2007-08-28 | 公開日 | 2007-10-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure and Activity of Y-Class DNA Polymerase Dpo4 from Sulfolobus Solfataricus with Templates Containing the Hydrophobic Thymine Analog 2,4- Difluorotoluene. J.Biol.Chem., 282, 2007
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7ZKE
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![BU of 7zke by Molmil](/molmil-images/mine/7zke) | Mot1:TBP:DNA - pre-hydrolysis state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (36-MER), ... | 著者 | Woike, S, Eustermann, S, Jung, J, Wenzl, S.J, Hagemann, G, Bartho, J.D, Lammens, K, Butryn, A, Herzog, F, Hopfner, K.-P. | 登録日 | 2022-04-12 | 公開日 | 2023-04-26 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1. Nat.Struct.Mol.Biol., 30, 2023
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3R6I
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![BU of 3r6i by Molmil](/molmil-images/mine/3r6i) | AKR1C3 complex with meclofenamic acid | 分子名称: | 1,2-ETHANEDIOL, 2-[(2,6-dichloro-3-methyl-phenyl)amino]benzoic acid, Aldo-keto reductase family 1 member C3, ... | 著者 | Yosaatmadja, Y, Teague, R.M, Flanagan, J.U, Squire, C.J. | 登録日 | 2011-03-21 | 公開日 | 2012-05-02 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3. Plos One, 7, 2012
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3R8H
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![BU of 3r8h by Molmil](/molmil-images/mine/3r8h) | AKR1C3 complex with zomepirac | 分子名称: | 1,2-ETHANEDIOL, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Yosaatmadja, Y, Teague, R.M, Flanagan, J.U, Squire, C.J. | 登録日 | 2011-03-24 | 公開日 | 2012-05-02 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3. Plos One, 7, 2012
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8BIP
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![BU of 8bip by Molmil](/molmil-images/mine/8bip) | Structure of a yeast 80S ribosome-bound N-Acetyltransferase B complex | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Knorr, A.G, Mackens-Kiani, T, Musial, J, Berninghausen, O, Becker, T, Beatrix, B, Beckmann, R. | 登録日 | 2022-11-02 | 公開日 | 2023-02-08 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The dynamic architecture of Map1- and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains. Plos Biol., 21, 2023
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8BJQ
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![BU of 8bjq by Molmil](/molmil-images/mine/8bjq) | Structure of a yeast 80S ribosome-bound N-Acetyltransferase B complex | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Knorr, A.G, Mackens-Kiani, T, Musial, J, Berninghausen, O, Becker, T, Beatrix, B, Beckmann, R. | 登録日 | 2022-11-05 | 公開日 | 2023-02-08 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | The dynamic architecture of Map1- and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains. Plos Biol., 21, 2023
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2XU1
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![BU of 2xu1 by Molmil](/molmil-images/mine/2xu1) | CATHEPSIN L WITH A NITRILE INHIBITOR | 分子名称: | (2S,4R)-1-[1-(4-chlorophenyl)cyclopropyl]carbonyl-4-(2-chlorophenyl)sulfonyl-N-[1-(iminomethyl)cyclopropyl]pyrrolidine-2-carboxamide, CATHEPSIN L1 | 著者 | Banner, D.W, Benz, J.M, Steinbacher, S, Haap, W. | 登録日 | 2010-10-14 | 公開日 | 2011-01-12 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Systematic Investigation of Halogen Bonding in Protein-Ligand Interactions. Angew.Chem.Int.Ed.Engl., 50, 2011
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2X0U
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![BU of 2x0u by Molmil](/molmil-images/mine/2x0u) | STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO A 2-amino substituted benzothiazole scaffold | 分子名称: | 6,7-DIHYDRO[1,4]DIOXINO[2,3-F][1,3]BENZOTHIAZOL-2-AMINE, CELLULAR TUMOR ANTIGEN P53, ZINC ION | 著者 | Joerger, A.C, Kaar, J.L, Basse, N, Fersht, A.R. | 登録日 | 2009-12-17 | 公開日 | 2010-01-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Toward the Rational Design of P53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant. Chem.Biol., 17, 2010
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5UPJ
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![BU of 5upj by Molmil](/molmil-images/mine/5upj) | HIV-2 PROTEASE/U99283 COMPLEX | 分子名称: | 5,6,7,8,9,10-HEXAHYDRO-4-HYDROXY-3-(1-PHENYLPROPYL)CYCLOOCTA[B]PYRAN-2-ONE, HIV-2 PROTEASE | 著者 | Watenpaugh, K.D, Mulichak, A.M, Finzel, B.C. | 登録日 | 1996-12-10 | 公開日 | 1997-04-21 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Use of medium-sized cycloalkyl rings to enhance secondary binding: discovery of a new class of human immunodeficiency virus (HIV) protease inhibitors. J.Med.Chem., 38, 1995
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5UP7
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![BU of 5up7 by Molmil](/molmil-images/mine/5up7) | Crystal Structure of the Ni-bound Human Heavy-Chain Ferritin 122H-delta C-star variant | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Bailey, J.B, Zhang, L, Chiong, J.A, Ahn, S, Tezcan, F.A. | 登録日 | 2017-02-01 | 公開日 | 2017-06-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Synthetic Modularity of Protein-Metal-Organic Frameworks. J. Am. Chem. Soc., 139, 2017
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3SZA
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![BU of 3sza by Molmil](/molmil-images/mine/3sza) | |
1DJC
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![BU of 1djc by Molmil](/molmil-images/mine/1djc) | |
3QEI
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![BU of 3qei by Molmil](/molmil-images/mine/3qei) | RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dCTP Opposite Difluorotoluene Nucleoside | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... | 著者 | Xia, S, Konigsberg, W.H, Wang, J. | 登録日 | 2011-01-20 | 公開日 | 2012-01-25 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.178 Å) | 主引用文献 | Structural Basis for Differential Insertion Kinetics of dNMPs Opposite a Difluorotoluene Nucleotide Residue. Biochemistry, 51, 2012
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5VN0
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![BU of 5vn0 by Molmil](/molmil-images/mine/5vn0) | Water-forming NADH oxidase from Lactobacillus brevis (LbNOX) bound to NADH. | 分子名称: | 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Cracan, V, Grabarek, Z. | 登録日 | 2017-04-28 | 公開日 | 2017-08-02 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | A genetically encoded tool for manipulation of NADP(+)/NADPH in living cells. Nat. Chem. Biol., 13, 2017
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2Y4O
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![BU of 2y4o by Molmil](/molmil-images/mine/2y4o) | Crystal Structure of PaaK2 in complex with phenylacetyl adenylate | 分子名称: | 5'-O-[HYDROXY(PHENYLACETYL)PHOSPHORYL]ADENOSINE, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ... | 著者 | Law, A, Boulanger, M.J. | 登録日 | 2011-01-07 | 公開日 | 2011-03-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Defining a Structural and Kinetic Rationale for Paralogous Copies of Phenylacetate-Coa Ligases from the Cystic Fibrosis Pathogen Burkholderia Cenocepacia J2315. J.Biol.Chem., 286, 2011
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2XWR
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![BU of 2xwr by Molmil](/molmil-images/mine/2xwr) | |
2Y27
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![BU of 2y27 by Molmil](/molmil-images/mine/2y27) | |
2Y4N
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![BU of 2y4n by Molmil](/molmil-images/mine/2y4n) | PaaK1 in complex with phenylacetyl adenylate | 分子名称: | 2-PHENYLACETIC ACID, 5'-O-[HYDROXY(PHENYLACETYL)PHOSPHORYL]ADENOSINE, BETA-MERCAPTOETHANOL, ... | 著者 | Law, A, Boulanger, M.J. | 登録日 | 2011-01-07 | 公開日 | 2011-03-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Defining a Structural and Kinetic Rationale for Paralogous Copies of Phenylacetate-Coa Ligases from the Cystic Fibrosis Pathogen Burkholderia Cenocepacia J2315. J.Biol.Chem., 286, 2011
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1DJB
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1DUH
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![BU of 1duh by Molmil](/molmil-images/mine/1duh) | CRYSTAL STRUCTURE OF THE CONSERVED DOMAIN IV OF E. COLI 4.5S RNA | 分子名称: | 4.5S RNA DOMAIN IV, LUTETIUM (III) ION, MAGNESIUM ION, ... | 著者 | Jovine, L, Hainzl, T, Oubridge, C, Scott, W.G, Li, J, Sixma, T.K, Wonacott, A, Skarzynski, T, Nagai, K. | 登録日 | 2000-01-17 | 公開日 | 2000-05-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of the ffh and EF-G binding sites in the conserved domain IV of Escherichia coli 4.5S RNA. Structure Fold.Des., 8, 2000
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5VTD
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![BU of 5vtd by Molmil](/molmil-images/mine/5vtd) | Crystal Structure of the Co-bound Human Heavy-Chain Ferritin variant 122H-delta C-star | 分子名称: | CALCIUM ION, CHLORIDE ION, COBALT (II) ION, ... | 著者 | Bailey, J.B, Zhang, L, Chiong, J.A, Tezcan, F.A. | 登録日 | 2017-05-16 | 公開日 | 2017-06-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Synthetic Modularity of Protein-Metal-Organic Frameworks. J. Am. Chem. Soc., 139, 2017
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2XU3
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![BU of 2xu3 by Molmil](/molmil-images/mine/2xu3) | CATHEPSIN L WITH A NITRILE INHIBITOR | 分子名称: | (2S,4R)-4-(2-chlorophenyl)sulfonyl-1-[1-(5-chlorothiophen-2-yl)cyclopropyl]carbonyl-N-[1-(iminomethyl)cyclopropyl]pyrrolidine-2-carboxamide, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CATHEPSIN L1, ... | 著者 | Banner, D.W, Benz, J.M, Haap, W. | 登録日 | 2010-10-14 | 公開日 | 2011-01-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (0.9 Å) | 主引用文献 | Systematic Investigation of Halogen Bonding in Protein-Ligand Interactions. Angew.Chem.Int.Ed.Engl., 50, 2011
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3RGP
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![BU of 3rgp by Molmil](/molmil-images/mine/3rgp) | |
3R94
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![BU of 3r94 by Molmil](/molmil-images/mine/3r94) | AKR1C3 complex with flurbiprofen | 分子名称: | (2R)-2-(3-fluoro-4-phenyl-phenyl)propanoic acid, 1,2-ETHANEDIOL, Aldo-keto reductase family 1 member C3, ... | 著者 | Yosaatmadja, Y, Teague, R.M, Flanagan, J.U, Squire, C.J. | 登録日 | 2011-03-24 | 公開日 | 2012-05-02 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.013 Å) | 主引用文献 | Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3. Plos One, 7, 2012
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