3R6I
AKR1C3 complex with meclofenamic acid
Summary for 3R6I
| Entry DOI | 10.2210/pdb3r6i/pdb |
| Related | 3R43 3R58 |
| Descriptor | Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-[(2,6-dichloro-3-methyl-phenyl)amino]benzoic acid, ... (5 entities in total) |
| Functional Keywords | tim barrel, aldo-keto reductase, nitro reductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P42330 |
| Total number of polymer chains | 1 |
| Total formula weight | 39141.06 |
| Authors | Yosaatmadja, Y.,Teague, R.M.,Flanagan, J.U.,Squire, C.J. (deposition date: 2011-03-21, release date: 2012-05-02, Last modification date: 2024-02-21) |
| Primary citation | Flanagan, J.U.,Yosaatmadja, Y.,Teague, R.M.,Chai, M.Z.,Turnbull, A.P.,Squire, C.J. Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3. Plos One, 7:e43965-e43965, 2012 Cited by PubMed: 22937138DOI: 10.1371/journal.pone.0043965 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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