3R8H

AKR1C3 complex with zomepirac

Summary for 3R8H

• Entry DOI: 10.2210/pdb3r8h/pdb
• Descriptor: Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrol-2-yl]acetic acid, ... (5 entities in total)
• Functional Keywords: tim barrel, zomepirac, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P42330
• Total number of polymer chains: 1
• Total formula weight: 39136.64

Authors

Yosaatmadja, Y.,Teague, R.M.,Flanagan, J.U.,Squire, C.J. (deposition date: 2011-03-24, release date: 2012-05-02, Last modification date: 2023-09-13)

• Primary citation: Flanagan, J.U.,Yosaatmadja, Y.,Teague, R.M.,Chai, M.Z.,Turnbull, A.P.,Squire, C.J.; Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3.; Plos One, 7:e43965-e43965, 2012; PubMed: 22937138; DOI: 10.1371/journal.pone.0043965

Experimental method

X-RAY DIFFRACTION (1.9 Å)