PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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6OM7	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-18 公開日 2019-06-19 最終更新日 2025-01-29 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6PUC	Structure of human MAIT A-F7 TCR in complex with human MR1-5-OP-RU 分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, CHLORIDE ION, ... 著者 Awad, W, Rossjohn, J. 登録日 2019-07-18 公開日 2020-02-19 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 The molecular basis underpinning the potency and specificity of MAIT cell antigens. Nat.Immunol., 21, 2020
6ZVJ	Structure of a human ABCE1-bound 43S pre-initiation complex - State II 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-07-24 公開日 2020-10-07 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes. Embo J., 40, 2021
4X46	X-RAY structure thymidine phosphorylase from Salmonella typhimurium complex with SO4 at 2.19 A 分子名称: 1,2-ETHANEDIOL, SULFATE ION, Thymidine phosphorylase 著者 Balaev, V.V, Lashkov, A.A, Prokofev, I.I, Gabdoulkhakov, A.G, Betzel, C, Mikhailov, A.M. 登録日 2014-12-02 公開日 2015-12-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 X-RAY structure thymidine phosphorylase from Salmonella typhimurium complex with SO4 at 2.19 A To Be Published
8CDR	Translocation intermediate 2 (TI-2) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. 登録日 2023-01-31 公開日 2023-09-20 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.04 Å) 主引用文献 mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
8CF5	Translocation intermediate 1 (TI-1) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. 登録日 2023-02-02 公開日 2023-09-20 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.71 Å) 主引用文献 mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
8CCS	80S S. cerevisiae ribosome with ligands in hybrid-1 pre-translocation (PRE-H1) complex 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. 登録日 2023-01-27 公開日 2023-09-20 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (1.97 Å) 主引用文献 mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
8CDL	80S S. cerevisiae ribosome with ligands in hybrid-2 pre-translocation (PRE-H2) complex 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. 登録日 2023-01-31 公開日 2023-09-20 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.72 Å) 主引用文献 mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
6PUD	Structure of human MAIT A-F7 TCR in complex with human MR1-5'OH-Pentyl-5-OP-U 分子名称: 6-[(5-hydroxypentyl)amino]-5-[(E)-propylideneamino]pyrimidine-2,4(1H,3H)-dione, Beta-2-microglobulin, Human TCR alpha chain, ... 著者 Awad, W, Rossjohn, J. 登録日 2019-07-18 公開日 2020-02-19 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The molecular basis underpinning the potency and specificity of MAIT cell antigens. Nat.Immunol., 21, 2020
6OLF	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-16 公開日 2019-06-19 最終更新日 2025-01-29 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OLE	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-16 公開日 2019-06-19 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OLI	Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC) 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-16 公開日 2019-06-19 最終更新日 2024-11-20 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
4OU1	Crystal structure of a computationally designed retro-aldolase covalently bound to folding probe 1 [(6-methoxynaphthalen-2-yl)(oxiran-2-yl)methanol] 分子名称: (1S,2S)-1-(6-methoxynaphthalen-2-yl)propane-1,2-diol, BENZOIC ACID, PHOSPHATE ION, ... 著者 Bhabha, G, Zhang, X, Ekiert, D.C. 登録日 2014-02-14 公開日 2014-03-05 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts. Proc.Natl.Acad.Sci.USA, 111, 2014
4MUM	Crystal structure of mitochondrial 5'(3')-deoxy ribonucleotidase alternative spliced variant 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Pachl, P, Rezacova, P. 登録日 2013-09-22 公開日 2014-02-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.271 Å) 主引用文献 Kinetic and structural characterization of an alternatively spliced variant of human mitochondrial 5'(3')-deoxyribonucleotidase. J Enzyme Inhib Med Chem, 30, 2015
5CZP	70S termination complex containing E. coli RF2 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Hoffer, E.D, Dunham, C.M. 登録日 2015-07-31 公開日 2016-10-12 最終更新日 2025-03-19 実験手法 X-RAY DIFFRACTION (3.29995918 Å) 主引用文献 Uniformity of Peptide Release Is Maintained by Methylation of Release Factors. Cell Rep, 17, 2016
4WZD	Complex of 70S ribosome with cognate tRNA-Tyr in the P-site 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. 登録日 2014-11-19 公開日 2015-06-10 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
7N2O	AS4.2-YEIH-HLA*B27 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ... 著者 Yang, X, Jude, K.M, Garcia, K.C. 登録日 2021-05-29 公開日 2022-12-07 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
7N2Q	AS4.3-YEIH-HLA*B27 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, AS4.3 T cell receptor beta chain, ... 著者 Yang, X, Jude, K.M, Garcia, K.C. 登録日 2021-05-29 公開日 2022-12-07 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
7N2S	AS3.1-PRPF3-HLA*B27 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ... 著者 Yang, X, Jude, K.M, Garcia, K.C. 登録日 2021-05-29 公開日 2022-12-07 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
7N2R	AS4.3-PRPF3-HLA*B27 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, ... 著者 Yang, X, Jude, K.M, Garcia, K.C. 登録日 2021-05-29 公開日 2022-12-07 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
7N2N	TCR-antigen complex AS4.2-PRPF3-HLA*B27 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ... 著者 Yang, X, Jude, K.M, Garcia, K.C. 登録日 2021-05-29 公開日 2022-12-07 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
7N2P	AS4.3-RNASEH2b-HLA*B27 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, AS4.3 T cell receptor beta chain, ... 著者 Yang, X, Jude, K.M, Garcia, K.C. 登録日 2021-05-29 公開日 2022-12-07 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
7R0D	Structure of NUDT15 in complex with Geranyl monophosphate 分子名称: Geranyl phosphate, MAGNESIUM ION, Probable 8-oxo-dGTP diphosphatase NUDT15 著者 Scaletti, E.R, Stenmark, P. 登録日 2022-02-01 公開日 2023-11-29 最終更新日 2024-09-04 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Kinetic and structural characterization of NUDT15 and NUDT18 as catalysts of isoprene pyrophosphate hydrolysis. Febs J., 2024
4WQY	Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G in the post-translocational state (without fusitic acid) 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Lin, J, Gagnon, M.G, Steitz, T.A. 登録日 2014-10-22 公開日 2015-01-28 最終更新日 2024-12-25 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation. Cell, 160, 2015
7NUI	Crystal structure of HLA-B*08:01 in complex with ELRSRYWAI viral peptide 分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... 著者 Mavridis, G, Giastas, P, Mpakali, A. 登録日 2021-03-12 公開日 2021-04-14 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of HLA-B*08:01 in complex with ELRSRYWAI viral peptide To Be Published

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