PDB: 9786 件ウェブページステータス検索Chemie searchBIRD

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4XXD	Crystal Structure of mid-region amyloid beta capture by solanezumab 分子名称: Amyloid-beta fragment, Fab Heavy Chain, Fab Light Chain 著者 Hermans, S.J, Crespi, G.A.N, Parker, M.W, Miles, L.A. 登録日 2015-01-30 公開日 2015-04-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Molecular basis for mid-region amyloid-beta capture by leading Alzheimer's disease immunotherapies. Sci Rep, 5, 2015
1HDK	Charcot-Leyden Crystal Protein - pCMBS Complex 分子名称: EOSINOPHIL LYSOPHOSPHOLIPASE, PARA-MERCURY-BENZENESULFONIC ACID 著者 Ackerman, S.J, Savage, M.P, Liu, L, Leonidas, D.D, Kwatia, M.A, Swaminathan, G.J, Acharya, K.R. 登録日 2000-11-16 公開日 2001-11-15 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Charcot-Leyden Crystal Protein (Galectin-10) is not a Dual Function Galectin with Lysophospholipase Activity But Binds a Lysophospholipase Inhibitor in a Novel Structural Fashion. J.Biol.Chem., 277, 2002
7JG1	Dimeric Immunoglobin A (dIgA) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Igh protein, ... 著者 Kumar Bharathkar, S, Parker, B.P, Malyutin, A.G, Stadtmueller, B.M. 登録日 2020-07-18 公開日 2020-11-11 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 The structures of Secretory and dimeric Immunoglobulin A. Elife, 9, 2020
7JG2	Secretory Immunoglobin A (SIgA) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Igh protein, ... 著者 Kumar Bharathkar, S, Parker, B.P, Malyutin, A.G, Stadtmueller, B.M. 登録日 2020-07-18 公開日 2020-11-11 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 The structures of Secretory and dimeric Immunoglobulin A. Elife, 9, 2020
2NYT	The APOBEC2 Crystal Structure and Functional Implications for AID 分子名称: Probable C->U-editing enzyme APOBEC-2, ZINC ION 著者 Prochnow, C, Bransteitter, R, Klein, M, Goodman, M, Chen, X. 登録日 2006-11-21 公開日 2007-01-09 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The APOBEC-2 crystal structure and functional implications for the deaminase AID. Nature, 445, 2007
2J88	Hyaluronidase in complex with a monoclonal IgG Fab fragment 分子名称: FAB, HYALURONONGLUCOSAMINIDASE 著者 Padavattan, S, Schirmer, T, Markovic-Housley, Z. 登録日 2006-10-23 公開日 2007-04-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Identification of a B-Cell Epitope of Hyaluronidase, a Major Bee Venom Allergen, from its Crystal Structure in Complex with a Specific Fab. J.Mol.Biol., 368, 2007
4TSA	Structure of a lysozyme FAb complex 分子名称: FAb Heavy Chain, FAb Light Chain, Lysozyme C 著者 Wensley, B. 登録日 2014-06-18 公開日 2015-07-08 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Structure of a lysozyme FAb complex To Be Published
2ZB5	Crystal structure of the measles virus hemagglutinin (complex-sugar-type) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin protein 著者 Hashiguchi, T, Kajikawa, M, Maita, N, Takeda, M, Kuroki, K, Sasaki, K, Kohda, D, Yanagi, Y, Maenaka, K. 登録日 2007-10-16 公開日 2007-11-06 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of measles virus hemagglutinin provides insight into effective vaccines Proc.Natl.Acad.Sci.Usa, 104, 2007
4HBC	Crystal structure of a conformation-dependent rabbit IgG Fab specific for amyloid prefibrillar oligomers 分子名称: Antigen Binding Fragment, Immunoglobulin IgG - Heavy Chain, Immunoglobulin IgG - Light Chain, ... 著者 Arai, H. 登録日 2012-09-27 公開日 2012-10-31 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Crystal structure of a conformation-dependent rabbit IgG Fab specific for amyloid prefibrillar oligomers. Biochim.Biophys.Acta, 1820, 2012
4KHT	Triple helix bundle of GP41 complexed with fab 8066 分子名称: 8066 heavy chain, 8066 light chain, Gp41 helix 著者 Li, M, Gustchina, A, Wlodawer, A. 登録日 2013-05-01 公開日 2014-03-12 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.817 Å) 主引用文献 Complexes of neutralizing and non-neutralizing affinity matured Fabs with a mimetic of the internal trimeric coiled-coil of HIV-1 gp41. Plos One, 8, 2013
2ZB6	Crystal structure of the measles virus hemagglutinin (oligo-sugar type) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin protein 著者 Hashiguchi, T, Kajikawa, M, Maita, N, Takeda, M, Kuroki, K, Sasaki, K, Kohda, D, Yanagi, Y, Maenaka, K. 登録日 2007-10-16 公開日 2007-11-06 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of measles virus hemagglutinin provides insight into effective vaccines Proc.Natl.Acad.Sci.Usa, 104, 2007
3DEL	The structure of CT381, the arginine binding protein from the periplasm Chlamydia trachomatis 分子名称: Arginine Binding Protein 著者 Petit, P, Vuillard, L, Spinelli, S. 登録日 2008-06-10 公開日 2009-06-16 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Exploiting antigenic diversity for vaccine design: the Chlamydia ArtJ paradigm. J.Biol.Chem., 2010
7AQX	Co-Crystal Structure of Variant Surface Glycoprotein VSG2 in complex with Nanobody VSG2(NB9) 分子名称: CITRIC ACID, Nanobody VSG2(NB9), SODIUM ION, ... 著者 Stebbins, C.E, Hempelmann, A. 登録日 2020-10-23 公開日 2021-11-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.499 Å) 主引用文献 Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome. Cell Rep, 37, 2021
7AQY	Co-Crystal Structure of Variant Surface Glycoprotein VSG2 in complex with Nanobody VSG2(NB11) 分子名称: Nanobody VSG2(NB11), Variant surface glycoprotein MITAT 1.2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Stebbins, C.E, Hempelmann, A, VanStraaten, M. 登録日 2020-10-23 公開日 2021-11-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome. Cell Rep, 37, 2021
7AR0	Co-Crystal Structure of Variant Surface Glycoprotein VSG2 in complex with Nanobody VSG2(NB19) 分子名称: Nanobody VSG2(NB19), Variant surface glycoprotein MITAT 1.2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Stebbins, C.E, Hempelmann, A. 登録日 2020-10-23 公開日 2021-11-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.139 Å) 主引用文献 Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome. Cell Rep, 37, 2021
7AQZ	Co-Crystal Structure of Variant Surface Glycoprotein VSG2 in complex with Nanobody VSG2(NB14) 分子名称: CITRIC ACID, Nanobody VSG2(NB14), SODIUM ION, ... 著者 Stebbins, C.E, Hempelmann, A, VanStraaten, M. 登録日 2020-10-23 公開日 2021-11-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome. Cell Rep, 37, 2021
7A65	Nanodisc reconstituted, drug-free human ABCB1 in complex with MRK16 Fab 分子名称: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ... 著者 Nosol, K, Locher, K.P. 登録日 2020-08-25 公開日 2020-10-14 最終更新日 2020-10-28 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1. Proc.Natl.Acad.Sci.USA, 117, 2020
7A6E	Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and tariquidar 分子名称: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ... 著者 Nosol, K, Locher, K.P. 登録日 2020-08-25 公開日 2020-10-14 最終更新日 2020-10-28 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1. Proc.Natl.Acad.Sci.USA, 117, 2020
7A25	Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing sybodies (Sb23) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... 著者 Hallberg, B.M, Das, H. 登録日 2020-08-16 公開日 2020-11-25 実験手法 ELECTRON MICROSCOPY (3.06 Å) 主引用文献 Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2. Nat Commun, 11, 2020
7A69	Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and vincristine 分子名称: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ... 著者 Nosol, K, Locher, K.P. 登録日 2020-08-25 公開日 2020-10-21 最終更新日 2020-10-28 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1. Proc.Natl.Acad.Sci.USA, 117, 2020
7A6F	Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and zosuquidar 分子名称: CHOLESTEROL, MRK16 Fab-fragment heavy chain, MRK16 Fab-fragment light chain, ... 著者 Nosol, K, Locher, K.P. 登録日 2020-08-25 公開日 2020-10-14 最終更新日 2020-10-28 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1. Proc.Natl.Acad.Sci.USA, 117, 2020
7A6C	Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and elacridar 分子名称: CHOLESTEROL, If kappa light chain, MRK16 Fab-fragment heavy chain, ... 著者 Nosol, K, Locher, K.P. 登録日 2020-08-25 公開日 2020-10-14 最終更新日 2020-10-28 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1. Proc.Natl.Acad.Sci.USA, 117, 2020
7A29	Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing sybodies (Sb23) 2-up conformation 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neutralising sybody (Sb23), ... 著者 Hallberg, B.M, Das, H. 登録日 2020-08-16 公開日 2020-10-21 最終更新日 2020-11-18 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2. Nat Commun, 11, 2020
5NQY	Structure of a fHbp(V1.4):PorA(P1.16) chimera. Fusion at fHbp position 309. 分子名称: Factor H binding protein variant B16_001,Major outer membrane protein P.IA,Factor H binding protein variant B16_001 著者 Johnson, S, Hollingshead, S, Lea, S.M, Tang, C.M. 登録日 2017-04-21 公開日 2018-02-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure-based design of chimeric antigens for multivalent protein vaccines. Nat Commun, 9, 2018
6DWZ	Hermes transposase deletion dimer complex with (C/G) DNA 分子名称: DNA (26-MER), DNA (5'-D(*GP*AP*GP*AP*AP*CP*AP*AP*CP*AP*AP*CP*AP*AP*G)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*AP*C)-3'), ... 著者 Dyda, F, Hickman, A.B. 登録日 2018-06-28 公開日 2018-09-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase. Nucleic Acids Res., 46, 2018

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