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1N2G
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Crystal Structure of a Pantothenate Synthetase from M. tuberculosis in complex with AMPCPP
分子名称: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ETHANOL, GLYCEROL, ...
著者Wang, S, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2002-10-22
公開日2003-04-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of a pantothenate synthetase from M. tuberculosis and its complexes with substrates and a reaction intermediate
Protein Sci., 12, 2003
6CN5
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HUMAN RETENOID-RELATED ORPHAN RECEPTOR-GAMMA LIGAND- BINDING DOMAIN IN COMPLEX WITH INDOLE LIGAND CP9b IN INVERSE AGONIST CONFORMATION
分子名称: 4-cyano-N-{3-[1-(cyclohexanecarbonyl)piperidin-4-yl]-1-methyl-1H-indol-5-yl}pyridine-2-carboxamide, Nuclear receptor ROR-gamma
著者Kauppi, B, Vajdos, F.
登録日2018-03-07
公開日2018-09-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist.
J. Med. Chem., 61, 2018
1L9Y
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FEZ-1-Y228A, A Mutant of the Metallo-beta-lactamase from Legionella gormanii
分子名称: CHLORIDE ION, FEZ-1 b-lactamase, GLYCEROL, ...
著者Garcia-Saez, I, Mercuri, P.S, Galleni, M, Dideberg, O.
登録日2002-03-27
公開日2003-07-01
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Three-dimensional Structure of FEZ-1, a Monomeric Subclass B3 Metallo-beta-lactamase from Fluoribacter gormanii, in Native Form and in Complex with -Captopril
J.Mol.Biol., 325, 2003
4DR4
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Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with codon, cognate transfer RNA anticodon stem-loop and multiple copies of paromomycin molecules bound
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G.
登録日2012-02-16
公開日2012-11-14
最終更新日2013-01-30
実験手法X-RAY DIFFRACTION (3.969 Å)
主引用文献A structural basis for streptomycin-induced misreading of the genetic code.
Nat Commun, 4, 2013
2KPE
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Refined structure of Glycophorin A transmembrane segment dimer in DPC micelles
分子名称: Glycophorin-A
著者Mineev, K.S, Bocharov, E.V, Goncharuk, M.V, Arseniev, A.S, Volynsky, P.E, Efremov, R.G.
登録日2009-10-13
公開日2010-09-22
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Dimeric structure of the transmembrane domain of glycophorin a in lipidic and detergent environments.
Acta Naturae, 3, 2011
2X7Y
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P450 BM3 F87A in complex with DMSO
分子名称: BIFUNCTIONAL P-450/NADPH-P450 REDUCTASE, DIMETHYL SULFOXIDE, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Kuper, J, Wong, T.S, Roccatano, D, Wilmanns, M, Schwaneberg, U.
登録日2010-03-04
公開日2011-03-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Role of Active-Site Phe87 in Modulating the Organic Co-Solvent Tolerance of Cytochrome P450 Bm3 Monooxygenase.
Acta Crystallogr.,Sect.F, 68, 2012
1MWW
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THE STRUCTURE OF THE HYPOTHETICAL PROTEIN HI1388.1 FROM HAEMOPHILUS INFLUENZAE REVEALS A TAUTOMERASE/MIF FOLD
分子名称: CHLORIDE ION, GLUTAMIC ACID, HYPOTHETICAL PROTEIN HI1388.1
著者Lehmann, C, Pullalarevu, S, Krajewski, W, Galkin, A, Howard, A, Herzberg, O, Structure 2 Function Project (S2F)
登録日2002-10-01
公開日2003-11-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structure of the Hypothetical Protein HI1388.1 from Haemophilus influenzae
To be Published
2WRX
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Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 3.0
分子名称: INSULIN A CHAIN, INSULIN B CHAIN, SODIUM ION
著者Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G.
登録日2009-09-02
公開日2010-02-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues.
Proc.Natl.Acad.Sci.USA, 107, 2010
1N2E
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Crystal Structure of a Pantothenate Synthetase from M. tuberculosis in complex with AMPCPP and pantoate
分子名称: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ETHANOL, GLYCEROL, ...
著者Wang, S, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2002-10-22
公開日2003-04-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structures of a pantothenate synthetase from M. tuberculosis and its complexes with substrates and a reaction intermediate
Protein Sci., 12, 2003
1MX0
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Structure of topoisomerase subunit
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SODIUM ION, ...
著者Corbett, K.D, Berger, J.M.
登録日2002-10-01
公開日2003-01-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the topoisomerase VI-B subunit: implications for type II topoisomerase mechanism and evolution
Embo J., 22, 2003
4PHY
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Functional conservation despite structural divergence in ligand-responsive RNA switches
分子名称: ACETATE ION, MAGNESIUM ION, RNA (26-MER), ...
著者Boerneke, M.A, Dibrov, S.M, Hermann, T.H.
登録日2014-05-07
公開日2015-02-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Functional conservation despite structural divergence in ligand-responsive RNA switches.
Proc.Natl.Acad.Sci.USA, 111, 2014
2X55
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Yersinia Pestis Plasminogen Activator Pla (Native)
分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, COAGULASE/FIBRINOLYSIN, SULFATE ION
著者Eren, E, Murphy, M, Goguen, J, van den Berg, B.
登録日2010-02-05
公開日2010-07-28
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献An Active Site Water Network in the Plasminogen Activator Pla from Yersinia Pestis
Structure, 18, 2010
6QKJ
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EgtB from Chloracidobacterium thermophilum, a type II sulfoxide synthase in complex with N,N,N-trimethyl-histidine
分子名称: CHLORIDE ION, FE (III) ION, IMIDAZOLE, ...
著者Stampfli, A.R, Badri, B.N, Schirmer, T, Seebeck, F.P.
登録日2019-01-29
公開日2019-03-27
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献An Alternative Active Site Architecture for O2Activation in the Ergothioneine Biosynthetic EgtB from Chloracidobacterium thermophilum.
J.Am.Chem.Soc., 141, 2019
2WSB
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BU of 2wsb by Molmil
Crystal structure of the short-chain dehydrogenase Galactitol- Dehydrogenase (GatDH) of Rhodobacter sphaeroides in complex with NAD
分子名称: GALACTITOL DEHYDROGENASE, MAGNESIUM ION, N-PROPANOL, ...
著者Carius, Y, Christian, H, Faust, A, Kornberger, P, Kohring, G.W, Giffhorn, F, Scheidig, A.J.
登録日2009-09-04
公開日2010-04-28
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structural Insight Into Substrate Differentiation of the Sugar-Metabolizing Enzyme Galactitol Dehydrogenase from Rhodobacter Sphaeroides D.
J.Biol.Chem., 285, 2010
2GN8
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Crystal structure of UDP-GlcNAc inverting 4,6-dehydratase in complex with NADP and UDP
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, UDP-GlcNAc C6 dehydratase, ...
著者Ishiyama, N, Creuzenet, C, Lam, J.S, Berghuis, A.M.
登録日2006-04-09
公開日2006-05-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Studies of FlaA1 from Helicobacter pylori Reveal the Mechanism for Inverting 4,6-Dehydratase Activity.
J.Biol.Chem., 281, 2006
1K2E
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BU of 1k2e by Molmil
crystal structure of a nudix protein from Pyrobaculum aerophilum
分子名称: ACETIC ACID, GLYCEROL, NICKEL (II) ION, ...
著者Wang, S, Mura, C, Sawaya, M.R, Cascio, D, Eisenberg, D.
登録日2001-09-26
公開日2002-04-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of a Nudix protein from Pyrobaculum aerophilum reveals a dimer with two intersubunit beta-sheets.
Acta Crystallogr.,Sect.D, 58, 2002
2X04
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BU of 2x04 by Molmil
Crystal structure of the PABC-TNRC6C complex
分子名称: POLYADENYLATE-BINDING PROTEIN 1, SULFATE ION, TRINUCLEOTIDE REPEAT-CONTAINING GENE 6C PROTEIN
著者Jinek, M, Fabian, M.R, Coyle, S.M, Sonenberg, N, Doudna, J.A.
登録日2009-12-04
公開日2010-01-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Structural Insights Into the Human Gw182-Pabc Interaction in Microrna-Mediated Deadenylation
Nat.Struct.Mol.Biol., 17, 2010
4DT9
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Crystal Structure of Aminoglycoside-2''-Phosphotransferase Type IVa in Complex with Guanosine
分子名称: APH(2'')-Id, GUANOSINE
著者Shi, K, Berghuis, A.M.
登録日2012-02-20
公開日2012-03-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for Dual Nucleotide Selectivity of Aminoglycoside 2''-Phosphotransferase IVa Provides Insight on Determinants of Nucleotide Specificity of Aminoglycoside Kinases.
J.Biol.Chem., 287, 2012
1N2J
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BU of 1n2j by Molmil
Crystal Structure of a Pantothenate Synthetase from M. tuberculosis in complex with pantoate
分子名称: BETA-ALANINE, ETHANOL, GLYCEROL, ...
著者Wang, S, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2002-10-22
公開日2003-04-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of a pantothenate synthetase from M. tuberculosis and its complexes with substrates and a reaction intermediate
Protein Sci., 12, 2003
4DTS
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BU of 4dts by Molmil
RB69 DNA Polymerase Ternary Complex with dCTP Opposite an Abasic Site and ddC/dG as the Penultimate Base-pair
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ...
著者Xia, S, Wang, J, Konigsberg, W.H.
登録日2012-02-21
公開日2012-06-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA.
Biochemistry, 51, 2012
4DTU
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RB69 DNA Polymerase Ternary Complex with dGTP Opposite an Abasic Site and ddC/dG as the Penultimate Base-pair
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ...
著者Xia, S, Wang, J, Konigsberg, W.H.
登録日2012-02-21
公開日2012-06-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA.
Biochemistry, 51, 2012
1JER
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CUCUMBER STELLACYANIN, CU2+, PH 7.0
分子名称: COPPER (II) ION, CUCUMBER STELLACYANIN
著者Hart, P.J, Nersissian, A.M, Herrmann, R.G, Nalbandyan, R.M, Valentine, J.S, Eisenberg, D.
登録日1996-08-21
公開日1997-02-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A missing link in cupredoxins: crystal structure of cucumber stellacyanin at 1.6 A resolution.
Protein Sci., 5, 1996
4DUZ
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Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, U13C, bound with streptomycin
分子名称: 16S rRNA, MAGNESIUM ION, STREPTOMYCIN, ...
著者Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G.
登録日2012-02-22
公開日2013-02-27
実験手法X-RAY DIFFRACTION (3.651 Å)
主引用文献A structural basis for streptomycin resistance
To be Published
1PU7
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Crystal structure of H.pylori 3-methyladenine DNA glycosylase (MagIII) bound to 3,9-dimethyladenine
分子名称: 3-METHYLADENINE DNA GLYCOSYLASE, 6-AMINO-3,9-DIMETHYL-9H-PURIN-3-IUM, BETA-MERCAPTOETHANOL
著者Eichman, B.F, O'Rourke, E.J, Radicella, J.P, Ellenberger, T.
登録日2003-06-24
公開日2003-10-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal structures of 3-methyladenine DNA glycosylase MagIII and the recognition of alkylated bases
Embo J., 22, 2003
2H2G
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The Structural Basis of Sirtuin substrate affinity
分子名称: HISTONE H3 PEPTIDE, NAD-dependent deacetylase, ZINC ION
著者Cosgrove, M.S, Wolberger, C.
登録日2006-05-18
公開日2006-11-28
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献The structural basis of sirtuin substrate affinity
Biochemistry, 45, 2006

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