PDB: 1302 件ウェブページステータス検索Chemie searchBIRD

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8W07	Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-402 分子名称: (1R,2S,4R)-N-cyclohexyl-5,6-bis(4-hydroxyphenyl)-N-(4-methoxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, (1S,2R,4S)-N-cyclohexyl-5,6-bis(4-hydroxyphenyl)-N-(4-methoxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, Estrogen receptor 著者 Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.K, Nettles, K.W. 登録日 2024-02-13 公開日 2024-06-12 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu. Proc.Natl.Acad.Sci.USA, 121, 2024
6AWB	Structure of 30S ribosomal subunit and RNA polymerase complex in non-rotated state 分子名称: 16S rRNA, 30S ribosomal protein S1, 30S ribosomal protein S10, ... 著者 Demo, G, Rasouly, A, Vasilyev, N, Loveland, A.B, Diaz-Avalos, R, Grigorieff, N, Nudler, E, Korostelev, A.A. 登録日 2017-09-05 公開日 2017-10-18 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (6.7 Å) 主引用文献 Structure of RNA polymerase bound to ribosomal 30S subunit. Elife, 6, 2017
6AWD	Structure of 30S (S1 depleted) ribosomal subunit and RNA polymerase complex 分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Demo, G, Rasouly, A, Vasilyev, N, Loveland, A.B, Diaz-Avalos, R, Grigorieff, N, Nudler, E, Korostelev, A.A. 登録日 2017-09-05 公開日 2017-10-18 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (8.1 Å) 主引用文献 Structure of RNA polymerase bound to ribosomal 30S subunit. Elife, 6, 2017
6TE3	Crystal Structure of full-length Human Lysyl Hydroxylase LH3 - Cocrystal with Fe2+, Mn2+, UDP 分子名称: 2-OXOGLUTARIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Chiapparino, A, De Giorgi, F, Scietti, L, Faravelli, S, Roscioli, T, Forneris, F. 登録日 2019-11-11 公開日 2021-05-19 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Identification of Regulatory Molecular 'Hot Spots' for LH/PLOD Collagen Glycosyltransferase Activity Int J Mol Sci, 2023
6AWC	Structure of 30S ribosomal subunit and RNA polymerase complex in rotated state 分子名称: 16S rRNA, 30S ribosomal protein S1, 30S ribosomal protein S10, ... 著者 Demo, G, Rasouly, A, Vasilyev, N, Loveland, A.B, Diaz-Avalos, R, Grigorieff, N, Nudler, E, Korostelev, A.A. 登録日 2017-09-05 公開日 2017-10-18 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (7.9 Å) 主引用文献 Structure of RNA polymerase bound to ribosomal 30S subunit. Elife, 6, 2017
6GDY	Crystal structure of 2OG oxygenase JMJD6 (aa 1-343) in complex with Fe(II) and 2OG 分子名称: 2-OXOGLUTARIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, ... 著者 Islam, M.S, Schofield, C.J, McDonough, M.A. 登録日 2018-04-24 公開日 2019-04-03 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Biochemical and structural investigations clarify the substrate selectivity of the 2-oxoglutarate oxygenase JMJD6. J.Biol.Chem., 294, 2019
6TEC	Crystal Structure of full-length Human Lysyl Hydroxylase LH3 - Cocrystal with Fe2+, Mn2+, UDP-Xylose 分子名称: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Chiapparino, A, De Giorgi, F, Scietti, L, Faravelli, S, Roscioli, T, Forneris, F. 登録日 2019-11-11 公開日 2021-05-19 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Identification of Regulatory Molecular 'Hot Spots' for LH/PLOD Collagen Glycosyltransferase Activity Int J Mol Sci, 2023
6TES	Crystal Structure of full-length Human Lysyl Hydroxylase LH3 - Cocrystal with Fe2+, Mn2+, UDP-Glucuronic Acid 分子名称: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Chiapparino, A, De Giorgi, F, Scietti, L, Faravelli, S, Roscioli, T, Forneris, F. 登録日 2019-11-12 公開日 2021-05-19 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Identification of Regulatory Molecular 'Hot Spots' for LH/PLOD Collagen Glycosyltransferase Activity Int J Mol Sci, 2023
6TEU	Crystal Structure of full-length Human Lysyl Hydroxylase LH3 - Val80Lys mutant - Cocrystal with Fe2+, Mn2+ 分子名称: 2-OXOGLUTARIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Chiapparino, A, De Giorgi, F, Scietti, L, Faravelli, S, Roscioli, T, Forneris, F. 登録日 2019-11-12 公開日 2021-05-19 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Identification of Regulatory Molecular 'Hot Spots' for LH/PLOD Collagen Glycosyltransferase Activity Int J Mol Sci, 2023
6TEZ	Crystal Structure of full-length Human Lysyl Hydroxylase LH3 - Val80Lys mutant - Cocrystal with Fe2+, Mn2+, UDP-Glucuronic Acid 分子名称: 2-OXOGLUTARIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Chiapparino, A, De Giorgi, F, Scietti, L, Faravelli, S, Roscioli, T, Forneris, F. 登録日 2019-11-12 公開日 2021-05-19 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Identification of Regulatory Molecular 'Hot Spots' for LH/PLOD Collagen Glycosyltransferase Activity Int J Mol Sci, 2023
6TEX	Crystal Structure of full-length Human Lysyl Hydroxylase LH3 - Val80Lys mutant - Cocrystal with Fe2+, Mn2+, UDP-Glucose 分子名称: 2-OXOGLUTARIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Chiapparino, A, De Giorgi, F, Scietti, L, Faravelli, S, Roscioli, T, Forneris, F. 登録日 2019-11-12 公開日 2021-05-19 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Identification of Regulatory Molecular 'Hot Spots' for LH/PLOD Collagen Glycosyltransferase Activity Int J Mol Sci, 2023
8B0F	CryoEM structure of C5b8-CD59 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Bubeck, D, Couves, E.C, Gardner, S. 登録日 2022-09-07 公開日 2023-02-22 最終更新日 2023-03-01 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural basis for membrane attack complex inhibition by CD59. Nat Commun, 14, 2023
6IGM	Cryo-EM Structure of Human SRCAP Complex 分子名称: Actin-related protein 6, Helicase SRCAP, RuvB-like 1, ... 著者 Feng, Y, Tian, Y, Wu, Z, Xu, Y. 登録日 2018-09-25 公開日 2019-07-24 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Cryo-EM structure of human SRCAP complex. Cell Res., 28, 2018
5X0V	Reduced form of regulatory domain of OxyR2 from Vibrio vulnificus 分子名称: CHLORIDE ION, CITRIC ACID, LysR family transcriptional regulator 著者 Jo, I, Ha, N.-C. 登録日 2017-01-23 公開日 2017-03-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The hydrogen peroxide hypersensitivity of OxyR2 in Vibrio vulnificus depends on conformational constraints J. Biol. Chem., 292, 2017
3LL8	Crystal Structure of Calcineurin in Complex with AKAP79 Peptide 分子名称: AKAP79 peptide, CALCIUM ION, Calcineurin subunit B type 1, ... 著者 Li, H, Hogan, P.G. 登録日 2010-01-28 公開日 2011-01-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Balanced interactions of calcineurin with AKAP79 regulate Ca(2+)-calcineurin-NFAT signaling. Nat.Struct.Mol.Biol., 19, 2012
2W57	Crystal structure of the Vibrio cholerae ferric uptake regulator (Fur) reveals structural rearrangement of the DNA-binding domains 分子名称: FERRIC UPTAKE REGULATION PROTEIN, ZINC ION 著者 Sheikh, M.A, Taylor, G.L. 登録日 2008-12-05 公開日 2009-01-20 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of the Vibrio Cholerae Ferric Uptake Regulator (Fur) Reveals Insights Into Metal Co-Ordination. Mol.Microbiol., 72, 2009
4ZDV	Crystal structure of LC3 in complex with FAM134B LIR 分子名称: Microtubule-associated proteins 1A/1B light chain 3A 著者 Khaminets, A, Grumati, P, Dikic, I, Akutsu, M. 登録日 2015-04-19 公開日 2015-06-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Regulation of endoplasmic reticulum turnover by selective autophagy. Nature, 522, 2015
6TQO	rrn anti-termination complex 分子名称: 30S ribosomal protein S10, 30S ribosomal protein S4, DNA-directed RNA polymerase subunit alpha, ... 著者 Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N. 登録日 2019-12-17 公開日 2020-08-05 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis. Mol.Cell, 79, 2020
4FTV	The complex between the high affinity version of A6 TCR (A6c134) and human Class I MHC HLA-A2 with the bound TAX nonameric peptide 分子名称: A6 alpha chain, A6 beta chain, Beta-2-microglobulin, ... 著者 Borbulevych, O.Y, Baker, B.M. 登録日 2012-06-28 公開日 2013-07-03 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Structure of a high affinity TCR reveals native binding to MHC with enhanced peptide specificity To be Published
8EHI	Cryo-EM structure of his-elemental paused elongation complex with an unfolded TL (2) 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. 登録日 2022-09-14 公開日 2023-03-01 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (5.5 Å) 主引用文献 An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
8EHF	Cryo-EM structure of his-elemental paused elongation complex with an unfolded TL (1) 分子名称: (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. 登録日 2022-09-14 公開日 2023-03-01 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
8EG8	Cryo-EM structure of consensus elemental paused elongation complex with a folded TL 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. 登録日 2022-09-12 公開日 2023-03-01 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
8EGB	Cryo-EM structure of consensus elemental paused elongation complex with an unfolded TL 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. 登録日 2022-09-12 公開日 2023-03-01 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
8EG7	Cryo-EM structure of pre-consensus elemental paused elongation complex 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. 登録日 2022-09-11 公開日 2023-03-01 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
8EHA	Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (out) 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. 登録日 2022-09-14 公開日 2023-03-01 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023

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