6TEX

Crystal Structure of full-length Human Lysyl Hydroxylase LH3 - Val80Lys mutant - Cocrystal with Fe2+, Mn2+, UDP-Glucose

Summary for 6TEX

• Entry DOI: 10.2210/pdb6tex/pdb
• Descriptor: Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... (9 entities in total)
• Functional Keywords: collagen, lysyl hydroxylase, hydroxylysine, galactosyltransferase, glucosyltransferase, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 84361.14

Authors

Chiapparino, A.,De Giorgi, F.,Scietti, L.,Faravelli, S.,Roscioli, T.,Forneris, F. (deposition date: 2019-11-12, release date: 2021-05-19, Last modification date: 2024-02-07)

• Primary citation: Mattoteia, D.,Chiapparino, A.,Fumagalli, M.,De Marco, M.,De Giorgi, F.,Negro, L.,Pinnola, A.,Faravelli, S.,Roscioli, T.,Scietti, L.,Forneris, F.; Identification of Regulatory Molecular 'Hot Spots' for LH/PLOD Collagen Glycosyltransferase Activity; Int J Mol Sci, 2023; DOI: 10.3390/ijms241311213

Experimental method

X-RAY DIFFRACTION (2.3 Å)