PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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4OII	West Nile Virus NS1 in complex with neutralizing 22NS1 antibody Fab 分子名称: Heavy Chain of Fab fragment of 22NS1 Antibody, Light Chain of Fab fragment of 22NS1 Antibody, NON-STRUCTURAL PROTEIN NS1 著者 Edeling, M.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2014-01-19 公開日 2014-03-05 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of Flavivirus NS1 assembly and antibody recognition. Proc.Natl.Acad.Sci.USA, 111, 2014
4OKS	Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Compound 19 [[6-(3,5-diaminophenyl)-1-(2-methoxy-5-nitrobenzyl)-1H-indol-3-yl]acetic acid] 分子名称: CALCIUM ION, Serine protease NS3, [6-(3,5-diaminophenyl)-1-(2-methoxy-5-nitrobenzyl)-1H-indol-3-yl]acetic acid 著者 Padyana, A.K. 登録日 2014-01-22 公開日 2014-03-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Integrated strategies for identifying leads that target the NS3 helicase of the hepatitis C virus. J.Med.Chem., 57, 2014
3UWP	Crystal structure of Dot1l in complex with 5-iodotubercidin 分子名称: (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, Histone-lysine N-methyltransferase, H3 lysine-79 specific, ... 著者 Yu, W, Tempel, W, Smil, D, Schapira, M, Li, Y, Vedadi, M, Nguyen, K.T, Wernimont, A.K, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Brown, P.J, Structural Genomics Consortium (SGC) 登録日 2011-12-02 公開日 2012-03-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors. Nat Commun, 3, 2012
3ENT	Crystal structure of Nitrollin, a betagamma-crystallin from Nitrosospira multiformis-in alternate space group (P65) 分子名称: Putative uncharacterized protein 著者 Aravind, P, Sankaranarayanan, R. 登録日 2008-09-26 公開日 2009-03-31 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Three-dimensional domain swapping in nitrollin, a single-domain betagamma-crystallin from Nitrosospira multiformis, controls protein conformation and stability but not dimerization J.Mol.Biol., 385, 2009
3UZZ	Crystal structure of 5beta-reductase (AKR1D1) E120H mutant in complex with NADP+ and delta4-androstenedione 分子名称: 3-oxo-5-beta-steroid 4-dehydrogenase, 4-ANDROSTENE-3-17-DIONE, CHLORIDE ION, ... 著者 Chen, M, Christianson, D.W, Penning, T.M. 登録日 2011-12-07 公開日 2012-03-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Conversion of Human Steroid 5beta-Reductase (AKR1D1) into 3β-Hydroxysteroid Dehydrogenase by Single Point Mutation E120H: EXAMPLE OF PERFECT ENZYME ENGINEERING. J.Biol.Chem., 287, 2012
3V61	Structure of S. cerevisiae PCNA conjugated to SUMO on lysine 164 分子名称: BARIUM ION, N-ETHYLMALEIMIDE, Proliferating cell nuclear antigen, ... 著者 Armstrong, A.A, Mohideen, F, Lima, C.D. 登録日 2011-12-18 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2. Nature, 483, 2012
3V6C	Crystal Structure of USP2 in complex with mutated ubiquitin 分子名称: CHLORIDE ION, GLYCEROL, Ubiquitin, ... 著者 Neculai, M, Ernst, A, Sidhu, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2011-12-19 公開日 2012-12-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of USP2 in complex with mutated ubiquitin To be Published
3UOA	Crystal structure of the MALT1 paracaspase (P21 form) 分子名称: MAGNESIUM ION, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, Z-Val-Arg-Pro-DL-Arg-fluoromethylketone 著者 Jeffrey, P.D, Yu, J.W, Shi, Y. 登録日 2011-11-16 公開日 2011-12-21 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of the mucosa-associated lymphoid tissue lymphoma translocation 1 (MALT1) paracaspase region. Proc.Natl.Acad.Sci.USA, 108, 2011
3UQ7	X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) mutant L240S F247L (L9S F16L) in presence of 10 mM cysteamine 分子名称: Gamma-aminobutyric-acid receptor subunit beta-1 著者 Gonzalez-Gutierrez, G, Lukk, T, Agarwal, V, Papke, D, Nair, S.K, Grosman, C. 登録日 2011-11-19 公開日 2012-04-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals. Proc.Natl.Acad.Sci.USA, 109, 2012
3EI2	Structure of hsDDB1-drDDB2 bound to a 16 bp abasic site containing DNA-duplex 分子名称: 5'-D(*DAP*DAP*DAP*DTP*DGP*DAP*DAP*DTP*(3DR)P*DAP*DAP*DGP*DCP*DAP*DGP*DG)-3', 5'-D(*DCP*DCP*DTP*DGP*DCP*DTP*DTP*DTP*DAP*DTP*DTP*DCP*DAP*DTP*DTP*DT)-3', DNA damage-binding protein 1, ... 著者 Scrima, A, Thoma, N.H. 登録日 2008-09-15 公開日 2009-01-20 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex. Cell(Cambridge,Mass.), 135, 2008
4OTN	Crystal structure of the C-terminal regulatory domain of murine GCN2 分子名称: 1,2-ETHANEDIOL, Eukaryotic translation initiation factor 2-alpha kinase 4, SULFATE ION 著者 He, H, Georgiadis, M.M. 登録日 2014-02-13 公開日 2014-04-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structures of GCN2 Protein Kinase C-terminal Domains Suggest Regulatory Differences in Yeast and Mammals. J.Biol.Chem., 289, 2014
3EAJ	Crystal structure of SARS-CoV main protease quadruple mutant STIF/A with two molecules in one asymmetric unit 分子名称: 3C-like proteinase 著者 Shi, J.H, Jayaraman, S, Song, J.X. 登録日 2008-08-26 公開日 2009-09-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 crystal structure of SARS-CoV Mpro mutant with two molecules one ASU To be Published
3UTE	Crystal structure of Aspergillus fumigatus UDP galactopyranose mutase sulfate complex 分子名称: ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... 著者 Dhatwalia, R, Singh, H, Tanner, J.J. 登録日 2011-11-25 公開日 2012-02-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal Structures and Small-angle X-ray Scattering Analysis of UDP-galactopyranose Mutase from the Pathogenic Fungus Aspergillus fumigatus. J.Biol.Chem., 287, 2012
3EB0	Crystal Structure of cgd4_240 from cryptosporidium Parvum in complex with indirubin E804 分子名称: 3-({[(3S)-3,4-dihydroxybutyl]oxy}amino)-1H,2'H-2,3'-biindol-2'-one, GLYCEROL, Putative uncharacterized protein 著者 Wernimont, A.K, Fedorov, O, Lam, A, Ali, A, Zhao, Y, Lew, J, Wasney, G, Vedadi, M, Kozieradzki, I, Schapira, M, Bochkarev, A, Wilstrom, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Hui, R, Lin, Y.H, Structural Genomics Consortium (SGC) 登録日 2008-08-26 公開日 2008-09-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal Structure of cgd4_240 from cryptosporidium Parvum in complex with indirubin E804 TO BE PUBLISHED
3EBK	Crystal structure of major allergens, Bla g 4 from cockroaches 分子名称: Allergen Bla g 4 著者 Tan, Y.W, Chan, S.L, Chew, F.T, Sivaraman, J, Mok, Y.K. 登録日 2008-08-28 公開日 2008-12-02 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of two major allergens, Bla g 4 and Per a 4, from cockroaches and their IgE binding epitopes. J.Biol.Chem., 284, 2008
4OAN	Crystal structure of a TRAP periplasmic solute binding protein from rhodopseudomonas palustris HaA2 (RPB_2686), TARGET EFI-510221, with density modeled as (S)-2-hydroxy-2-methyl-3-oxobutanoate ((S)-2-Acetolactate) 分子名称: (2S)-2-hydroxy-2-methyl-3-oxobutanoic acid, CHLORIDE ION, GLYCEROL, ... 著者 Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) 登録日 2014-01-05 公開日 2014-01-22 最終更新日 2015-02-25 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry, 54, 2015
3V4S	Crystal Structure of ADP-ATP complex of purK: N5-carboxyaminoimidazole ribonucleotide synthetase 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CARBONATE ION, ... 著者 Fung, L.W, Tuntland, M.L, Santarsiero, B.D, Johnson, M.E. 登録日 2011-12-15 公開日 2013-02-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Elucidation of the bicarbonate binding site and insights into the carboxylation mechanism of (N(5))-carboxyaminoimidazole ribonucleotide synthase (PurK) from Bacillus anthracis. Acta Crystallogr.,Sect.D, 70, 2014
3V78	Crystal Structure of Transcriptional Regulator 分子名称: ETHIDIUM, PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY DEOR-FAMILY) 著者 Do, S.V, Bolla, J.R, Chen, X, Yu, E.W. 登録日 2011-12-20 公開日 2012-12-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.299 Å) 主引用文献 Structural and functional analysis of the transcriptional regulator Rv3066 of Mycobacterium tuberculosis. Nucleic Acids Res., 40, 2012
3V5Y	Structure of FBXL5 hemerythrin domain, P2(1) cell 分子名称: F-box/LRR-repeat protein 5, MU-OXO-DIIRON 著者 Tomchick, D.R, Bruick, R.K, Thompson, J.W, Brautigam, C.A. 登録日 2011-12-17 公開日 2012-01-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and Molecular Characterization of Iron-sensing Hemerythrin-like Domain within F-box and Leucine-rich Repeat Protein 5 (FBXL5). J.Biol.Chem., 287, 2012
3V7I	Germicidin synthase (Gcs) from Streptomyces coelicolor, a type III polyketide synthase 分子名称: Putative polyketide synthase 著者 Akey, D.L, Smith, J.L, Geders, T.W. 登録日 2011-12-21 公開日 2012-04-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Biochemical and Structural Characterization of Germicidin Synthase: Analysis of a Type III Polyketide Synthase That Employs Acyl-ACP as a Starter Unit Donor. J.Am.Chem.Soc., 134, 2012
3ENB	Crystal Structure of PRP8 core domain IV 分子名称: Pre-mRNA-processing-splicing factor 8 著者 Schellenberg, M.J, Ritchie, D.B, MacMillan, A.M. 登録日 2008-09-25 公開日 2008-10-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural elucidation of a PRP8 core domain from the heart of the spliceosome. Nat.Struct.Mol.Biol., 15, 2008
4OGN	Co-Crystal Structure of MDM2 with Inhbitor Compound 3 分子名称: 6-{[(3R,5R,6S)-1-[(1S)-2-(tert-butylsulfonyl)-1-cyclopropylethyl]-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-2-oxopiperidin-3-yl]methyl}pyridine-3-carboxylic acid, E3 ubiquitin-protein ligase Mdm2, SULFATE ION 著者 Shaffer, P.L, Huang, X, Yakowec, P, Long, A.M. 登録日 2014-01-16 公開日 2014-04-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.377 Å) 主引用文献 Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydrogen Bond Acceptors as Carboxylic Acid Isosteres. J.Med.Chem., 57, 2014
4O8C	Structure of the H170Y mutant of thermostable p-nitrophenylphosphatase from Bacillus Stearothermophilus 分子名称: MAGNESIUM ION, SULFATE ION, Thermostable NPPase 著者 Shen, T, Guo, Z, Wang, F, Gong, W, Ji, C. 登録日 2013-12-27 公開日 2014-06-18 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of a His170Tyr mutant of thermostable pNPPase from Geobacillus stearothermophilus. Acta Crystallogr.,Sect.F, 70, 2014
3EOY	Structure of Reovirus sigma1 in Complex with Its Receptor Junctional Adhesion Molecule-A 分子名称: Junctional adhesion molecule A, Outer capsid protein sigma-1 著者 Kirchner, E, Guglielmi, K.M, Dermody, T.S, Stehle, T. 登録日 2008-09-29 公開日 2008-11-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structure of reovirus sigma1 in complex with its receptor junctional adhesion molecule-A Plos Pathog., 4, 2008
4OGT	Co-Crystal Structure of MDM2 with Inhbitor Compound 46 分子名称: 6-{[(2R,5R,6R)-4-[(1S)-2-(tert-butylsulfonyl)-1-cyclopropylethyl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-2-methyl-3-oxomorpholin-2-yl]methyl}pyridine-3-carboxylic acid, E3 ubiquitin-protein ligase Mdm2, SULFATE ION 著者 Shaffer, P.L, Huang, X, Yakowec, P, Long, A.M. 登録日 2014-01-16 公開日 2014-04-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5361 Å) 主引用文献 Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydrogen Bond Acceptors as Carboxylic Acid Isosteres. J.Med.Chem., 57, 2014

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